CL2007002766A1 - Composicion farmaceutica en forma de capsula que comprende un granulo con un compuesto derivado de pirimidil-amino-benzamida en mezcla intima con al menos un excipiente farmaceuticamente aceptable; metodo de preparacion de dicha composicion, util par - Google Patents
Composicion farmaceutica en forma de capsula que comprende un granulo con un compuesto derivado de pirimidil-amino-benzamida en mezcla intima con al menos un excipiente farmaceuticamente aceptable; metodo de preparacion de dicha composicion, util parInfo
- Publication number
- CL2007002766A1 CL2007002766A1 CL200702766A CL2007002766A CL2007002766A1 CL 2007002766 A1 CL2007002766 A1 CL 2007002766A1 CL 200702766 A CL200702766 A CL 200702766A CL 2007002766 A CL2007002766 A CL 2007002766A CL 2007002766 A1 CL2007002766 A1 CL 2007002766A1
- Authority
- CL
- Chile
- Prior art keywords
- composition
- granulum
- pyrimidil
- benzamide
- capsule
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title 1
- 239000002131 composite material Substances 0.000 title 1
- 239000011872 intimate mixture Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000546 pharmaceutical excipient Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06121371A EP1923053A1 (en) | 2006-09-27 | 2006-09-27 | Pharmaceutical compositions comprising nilotinib or its salt |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2007002766A1 true CL2007002766A1 (es) | 2008-08-08 |
Family
ID=37684496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200702766A CL2007002766A1 (es) | 2006-09-27 | 2007-09-26 | Composicion farmaceutica en forma de capsula que comprende un granulo con un compuesto derivado de pirimidil-amino-benzamida en mezcla intima con al menos un excipiente farmaceuticamente aceptable; metodo de preparacion de dicha composicion, util par |
Country Status (35)
Country | Link |
---|---|
US (2) | US8293756B2 (es) |
EP (4) | EP1923053A1 (es) |
JP (2) | JP5567340B2 (es) |
KR (2) | KR20090076931A (es) |
CN (2) | CN104306350A (es) |
AR (1) | AR062980A1 (es) |
AU (1) | AU2007301977B2 (es) |
BR (1) | BRPI0719438B1 (es) |
CA (1) | CA2662571C (es) |
CL (1) | CL2007002766A1 (es) |
CO (1) | CO6160288A2 (es) |
CY (2) | CY1117021T1 (es) |
DK (2) | DK2068839T3 (es) |
ES (3) | ES2957912T3 (es) |
FI (2) | FI3984528T3 (es) |
HK (1) | HK1133193A1 (es) |
HR (2) | HRP20230753T3 (es) |
HU (2) | HUE028204T2 (es) |
IL (1) | IL197496A (es) |
JO (1) | JO3757B1 (es) |
LT (1) | LT3984528T (es) |
MA (1) | MA30807B1 (es) |
MX (1) | MX2009003184A (es) |
MY (1) | MY148237A (es) |
NO (2) | NO347404B1 (es) |
NZ (1) | NZ575317A (es) |
PE (2) | PE20081379A1 (es) |
PL (2) | PL2068839T5 (es) |
PT (2) | PT3984528T (es) |
RU (1) | RU2469707C2 (es) |
SI (2) | SI3984528T1 (es) |
TN (1) | TN2009000093A1 (es) |
TW (3) | TW201418245A (es) |
WO (1) | WO2008037716A2 (es) |
ZA (1) | ZA200901511B (es) |
Families Citing this family (29)
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EP1923053A1 (en) * | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
AU2010299756A1 (en) | 2009-09-28 | 2012-04-19 | Medizinische Universitat Wien | PDGFRbeta inhibitors for use in the treatment of T-cell lymphoma |
RU2012120901A (ru) * | 2009-10-23 | 2013-12-10 | Новартис Аг | Способ лечения пролиферативных расстройств и других патологических состояний, опосредованных действием киназ bcr-abl, c-kit, ddr1, ddr2 или pdgf-r |
JO3634B1 (ar) | 2009-11-17 | 2020-08-27 | Novartis Ag | طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r |
WO2012164578A1 (en) * | 2011-06-02 | 2012-12-06 | Hetero Research Foundation | Compositions and methods for preparing immediate release formulations of nilotinib |
AR086913A1 (es) * | 2011-06-14 | 2014-01-29 | Novartis Ag | 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas |
CN102321073A (zh) * | 2011-08-12 | 2012-01-18 | 西安交通大学 | 一种尼罗替尼的制备方法 |
WO2013063003A1 (en) | 2011-10-28 | 2013-05-02 | Novartis Ag | Method of treating gastrointestinal stromal tumors |
WO2013063000A1 (en) | 2011-10-28 | 2013-05-02 | Novartis Ag | Method of treating gastrointestinal stromal tumors |
AR088844A1 (es) * | 2011-11-14 | 2014-07-10 | Novartis Ag | Formulacion de liberacion inmediata de 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida |
US9301957B2 (en) | 2011-11-14 | 2016-04-05 | Novartis Ag | Immediate release 4-methyl-3-4[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-YL)-3-(trifluoromethyl)phenyl] benzamide formulation |
IN2014DN10801A (es) | 2012-07-11 | 2015-09-04 | Novartis Ag | |
WO2014174496A1 (en) | 2013-04-25 | 2014-10-30 | Ranbaxy Laboratories Limited | Pharmaceutical gastro-retentive solid oral dosage form of nilotinib |
US9636340B2 (en) | 2013-11-12 | 2017-05-02 | Ayyappan K. Rajasekaran | Kinase inhibitors |
WO2016024289A2 (en) | 2014-08-11 | 2016-02-18 | Sun Pharmaceutical Industries Ltd | Novel salts of nilotinib and polymorphs thereof |
WO2016033304A1 (en) * | 2014-08-28 | 2016-03-03 | Codexis, Inc. | Imidazoyl anilide derivatives and methods of use |
AU2017232868B2 (en) * | 2016-03-17 | 2021-07-22 | Sun Pharmaceutical Industries Ltd. | Pharmaceutical composition of nilotinib |
CN107582531B (zh) * | 2016-07-06 | 2020-12-29 | 四川科伦药物研究院有限公司 | 一种利伐沙班固体制剂及其制备方法 |
CN107320460B (zh) * | 2017-08-04 | 2020-11-03 | 北京化工大学 | 一种尼罗替尼口服纳米制剂及其制备方法 |
CN107441094B (zh) * | 2017-08-08 | 2020-05-22 | 南方医科大学 | 尼罗替尼作为治疗登革病毒感染的药物及其制药用途 |
CZ2017821A3 (cs) | 2017-12-20 | 2019-07-03 | Zentiva, K.S. | Léková forma obsahující krystalický nilotinib |
AU2019285066B2 (en) | 2018-06-15 | 2024-06-13 | Handa Pharmaceuticals, Inc. | Kinase inhibitor salts and compositions thereof |
IL295007A (en) | 2020-01-31 | 2022-09-01 | Nanocopoeia Llc | Amorphous nilotinib microparticles and uses thereof |
WO2021222739A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
JP7489849B2 (ja) | 2020-07-20 | 2024-05-24 | 日本化薬株式会社 | ニロチニブ錠剤 |
AU2022292092A1 (en) | 2021-06-19 | 2024-02-01 | Helm Ag | Granulate composition comprising nilotinib |
WO2023285981A1 (en) * | 2021-07-15 | 2023-01-19 | Torrent Pharmaceuticals Limited | Stable pharmaceutical liquid composition of nilotinib |
EP4122452A1 (en) | 2021-07-23 | 2023-01-25 | KRKA, d.d., Novo mesto | Pharmaceutical composition comprising nilotinib and method of manufacturing the same |
EP4260848A1 (en) | 2022-04-11 | 2023-10-18 | Lotus Pharmaceutical Co., Ltd. | Pharmaceutical composition for solid dosage form containing nilotinib and process for its preparation |
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EP1923053A1 (en) | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
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2006
- 2006-09-27 EP EP06121371A patent/EP1923053A1/en not_active Ceased
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2007
- 2007-09-23 JO JOP/2007/0402A patent/JO3757B1/ar active
- 2007-09-25 EP EP21194622.3A patent/EP3984528B1/en active Active
- 2007-09-25 HR HRP20230753TT patent/HRP20230753T3/hr unknown
- 2007-09-25 CA CA2662571A patent/CA2662571C/en active Active
- 2007-09-25 MY MYPI20091044A patent/MY148237A/en unknown
- 2007-09-25 ES ES15184282T patent/ES2957912T3/es active Active
- 2007-09-25 HU HUE07820560A patent/HUE028204T2/en unknown
- 2007-09-25 NO NO20220946A patent/NO347404B1/no unknown
- 2007-09-25 LT LTEP21194622.3T patent/LT3984528T/lt unknown
- 2007-09-25 MX MX2009003184A patent/MX2009003184A/es active IP Right Grant
- 2007-09-25 CN CN201410535689.8A patent/CN104306350A/zh active Pending
- 2007-09-25 PT PT211946223T patent/PT3984528T/pt unknown
- 2007-09-25 KR KR1020097008418A patent/KR20090076931A/ko not_active Application Discontinuation
- 2007-09-25 FI FIEP21194622.3T patent/FI3984528T3/fi active
- 2007-09-25 RU RU2009115782/15A patent/RU2469707C2/ru active
- 2007-09-25 DK DK07820560.6T patent/DK2068839T3/da active
- 2007-09-25 WO PCT/EP2007/060165 patent/WO2008037716A2/en active Application Filing
- 2007-09-25 KR KR1020147027439A patent/KR101598747B1/ko active IP Right Grant
- 2007-09-25 SI SI200732199T patent/SI3984528T1/sl unknown
- 2007-09-25 PE PE2007001294A patent/PE20081379A1/es active IP Right Grant
- 2007-09-25 NZ NZ575317A patent/NZ575317A/en unknown
- 2007-09-25 AR ARP070104231A patent/AR062980A1/es not_active Application Discontinuation
- 2007-09-25 SI SI200731724T patent/SI2068839T2/sl unknown
- 2007-09-25 FI FIEP07820560.6T patent/FI2068839T4/fi active
- 2007-09-25 PL PL07820560.6T patent/PL2068839T5/pl unknown
- 2007-09-25 ES ES07820560T patent/ES2556625T5/es active Active
- 2007-09-25 HR HRP20151383TT patent/HRP20151383T4/hr unknown
- 2007-09-25 US US12/442,544 patent/US8293756B2/en active Active
- 2007-09-25 PE PE2012000043A patent/PE20120626A1/es not_active Application Discontinuation
- 2007-09-25 AU AU2007301977A patent/AU2007301977B2/en active Active
- 2007-09-25 EP EP07820560.6A patent/EP2068839B2/en active Active
- 2007-09-25 BR BRPI0719438-2A patent/BRPI0719438B1/pt active IP Right Grant
- 2007-09-25 JP JP2009529688A patent/JP5567340B2/ja active Active
- 2007-09-25 PT PT78205606T patent/PT2068839E/pt unknown
- 2007-09-25 HU HUE21194622A patent/HUE063083T2/hu unknown
- 2007-09-25 NO NO20091501A patent/NO346639B1/no unknown
- 2007-09-25 DK DK21194622.3T patent/DK3984528T3/da active
- 2007-09-25 EP EP15184282.0A patent/EP3009128B1/en active Active
- 2007-09-25 ES ES21194622T patent/ES2951547T3/es active Active
- 2007-09-25 PL PL21194622.3T patent/PL3984528T3/pl unknown
- 2007-09-25 CN CNA2007800353567A patent/CN101516344A/zh active Pending
- 2007-09-26 TW TW103101056A patent/TW201418245A/zh unknown
- 2007-09-26 CL CL200702766A patent/CL2007002766A1/es unknown
- 2007-09-26 TW TW102144088A patent/TWI540128B/zh active
- 2007-09-26 TW TW096135768A patent/TWI428333B/zh active
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2009
- 2009-03-03 ZA ZA2009/01511A patent/ZA200901511B/en unknown
- 2009-03-09 IL IL197496A patent/IL197496A/en active IP Right Grant
- 2009-03-19 TN TN2009000093A patent/TN2009000093A1/fr unknown
- 2009-04-22 MA MA31809A patent/MA30807B1/fr unknown
- 2009-04-24 CO CO09041795A patent/CO6160288A2/es unknown
- 2009-12-04 HK HK09111400.2A patent/HK1133193A1/xx active IP Right Maintenance
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2012
- 2012-09-21 US US13/624,354 patent/US8501760B2/en active Active
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2013
- 2013-11-07 JP JP2013231327A patent/JP2014065715A/ja active Pending
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2015
- 2015-12-16 CY CY20151101150T patent/CY1117021T1/el unknown
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2023
- 2023-07-27 CY CY20231100367T patent/CY1126116T1/el unknown
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