ECSP099536A - Métodos y formulaciones para biodisponibilidad mejorada de antiprogestinas - Google Patents
Métodos y formulaciones para biodisponibilidad mejorada de antiprogestinasInfo
- Publication number
- ECSP099536A ECSP099536A EC2009009536A ECSP099536A ECSP099536A EC SP099536 A ECSP099536 A EC SP099536A EC 2009009536 A EC2009009536 A EC 2009009536A EC SP099536 A ECSP099536 A EC SP099536A EC SP099536 A ECSP099536 A EC SP099536A
- Authority
- EC
- Ecuador
- Prior art keywords
- antiprogestines
- formulations
- methods
- improved
- biodisponibility
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
La presente invención se refiere en términos generales a composiciones con biodisponibilidad mejorada que comprenden por lo menos una antiprogestina. Más particularmente, la invención presente se relaciona con una potente actividad antiporgestacional, actividad antiglucocorticoide mínima y biodisponibilidad mejorada, comprendiendo un derivado de 19-norprogesterona I y opcionalmente un excipiente farmacéuticamente aceptable.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88242306P | 2006-12-28 | 2006-12-28 | |
US88537207P | 2007-01-17 | 2007-01-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099536A true ECSP099536A (es) | 2009-08-28 |
Family
ID=39589194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009536A ECSP099536A (es) | 2006-12-28 | 2009-07-23 | Métodos y formulaciones para biodisponibilidad mejorada de antiprogestinas |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP2094275A2 (es) |
JP (1) | JP2010514793A (es) |
KR (1) | KR20090086470A (es) |
AR (1) | AR064697A1 (es) |
AU (1) | AU2007339820A1 (es) |
CA (1) | CA2672888A1 (es) |
CL (1) | CL2007003855A1 (es) |
CO (1) | CO6190605A2 (es) |
EA (1) | EA200970646A1 (es) |
EC (1) | ECSP099536A (es) |
MX (1) | MX2009006912A (es) |
NO (1) | NO20092271L (es) |
TW (1) | TW200831110A (es) |
WO (1) | WO2008083192A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8299050B2 (en) | 2008-01-29 | 2012-10-30 | Laboratoire Hra-Pharma | Method for treating uterine fibroids |
US8512745B2 (en) | 2008-12-08 | 2013-08-20 | Laboratoire Hra Pharma | Ulipristal acetate tablets |
ME02548B (me) | 2009-04-14 | 2017-02-20 | Hra Pharma Lab | Postupak za kontracepciju po potrebi |
EP2471537A1 (en) * | 2010-12-30 | 2012-07-04 | PregLem S.A. | Treatment of pain associated with dislocation of basal endometrium |
EP2545922A1 (en) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Treatment of excessive menstrual bleeding associated with uterine fibroids |
WO2013059664A1 (en) * | 2011-10-21 | 2013-04-25 | Seachaid Pharmaceuticals, Inc. | Pharmaceutical compositions and uses thereof |
FR2997627B1 (fr) * | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant de l'ulipristal acetate |
FR2997628B1 (fr) * | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone |
FR2999081B1 (fr) * | 2012-12-06 | 2015-02-27 | Hra Pharma Lab | Dispersion solide d'un modulateur selectif du recepteur a la progesterone |
SG11201507260QA (en) | 2013-04-10 | 2015-10-29 | Preglem Sa | Progesteron receptor modulators for use in the therapy of uterine fibroids |
WO2018106914A1 (en) * | 2016-12-09 | 2018-06-14 | Repros Therapeutics Inc. | Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent |
WO2017216637A2 (en) | 2017-08-04 | 2017-12-21 | Alvogen Malta Operations (Row) Ltd | Tablet form including ulipristal acetate and the methods for its preparation |
WO2023033900A1 (en) | 2021-09-06 | 2023-03-09 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2668824A1 (en) * | 1996-05-01 | 1997-11-06 | The Government Of The United States Of America, Represented By The Secre Tary Of The Department Of Health And Human Services | 21-substituted progesterone derivatives as new antiprogestational agents |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
FR2821555B1 (fr) * | 2001-03-01 | 2003-05-16 | Besins Int Lab | Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations |
US20050220825A1 (en) * | 2004-03-10 | 2005-10-06 | Adrian Funke | Molecular dispersions of drospirenone |
CA2623678A1 (en) * | 2005-09-29 | 2007-04-05 | Repros Therapeutics Inc. | Formulations with improved bioavailability, comprising a steroid derivative and a polyglycolysed glyceride |
-
2007
- 2007-12-27 CA CA002672888A patent/CA2672888A1/en not_active Abandoned
- 2007-12-27 MX MX2009006912A patent/MX2009006912A/es not_active Application Discontinuation
- 2007-12-27 TW TW096150635A patent/TW200831110A/zh unknown
- 2007-12-27 KR KR1020097014099A patent/KR20090086470A/ko not_active Application Discontinuation
- 2007-12-27 JP JP2009544257A patent/JP2010514793A/ja active Pending
- 2007-12-27 WO PCT/US2007/088891 patent/WO2008083192A2/en active Application Filing
- 2007-12-27 EA EA200970646A patent/EA200970646A1/ru unknown
- 2007-12-27 AU AU2007339820A patent/AU2007339820A1/en not_active Abandoned
- 2007-12-27 EP EP07869940A patent/EP2094275A2/en not_active Withdrawn
- 2007-12-28 CL CL200703855A patent/CL2007003855A1/es unknown
- 2007-12-28 AR ARP070105971A patent/AR064697A1/es unknown
-
2009
- 2009-06-12 NO NO20092271A patent/NO20092271L/no not_active Application Discontinuation
- 2009-06-25 CO CO09066124A patent/CO6190605A2/es not_active Application Discontinuation
- 2009-07-23 EC EC2009009536A patent/ECSP099536A/es unknown
Also Published As
Publication number | Publication date |
---|---|
TW200831110A (en) | 2008-08-01 |
WO2008083192A8 (en) | 2009-07-09 |
AU2007339820A1 (en) | 2008-07-10 |
NO20092271L (no) | 2009-08-06 |
WO2008083192A2 (en) | 2008-07-10 |
EP2094275A2 (en) | 2009-09-02 |
EA200970646A1 (ru) | 2009-12-30 |
KR20090086470A (ko) | 2009-08-12 |
JP2010514793A (ja) | 2010-05-06 |
CL2007003855A1 (es) | 2008-03-14 |
CA2672888A1 (en) | 2008-07-10 |
AR064697A1 (es) | 2009-04-22 |
CO6190605A2 (es) | 2010-08-19 |
MX2009006912A (es) | 2009-08-12 |
WO2008083192A3 (en) | 2008-11-27 |
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