MA23606A1 - Procede de preparation du trihydrate du (2r, 3s) -3-tert-butoxycarbonylamino -2-hydroxy-3- phenylpropionate de 4-acetoxy-2a- benzoyloxy-5b , 20-epoxy-1.7b, 10b- trihydroxy- 9- oxo-tax-11- en-13 a-yle. - Google Patents

Procede de preparation du trihydrate du (2r, 3s) -3-tert-butoxycarbonylamino -2-hydroxy-3- phenylpropionate de 4-acetoxy-2a- benzoyloxy-5b , 20-epoxy-1.7b, 10b- trihydroxy- 9- oxo-tax-11- en-13 a-yle.

Info

Publication number
MA23606A1
MA23606A1 MA23945A MA23945A MA23606A1 MA 23606 A1 MA23606 A1 MA 23606A1 MA 23945 A MA23945 A MA 23945A MA 23945 A MA23945 A MA 23945A MA 23606 A1 MA23606 A1 MA 23606A1
Authority
MA
Morocco
Prior art keywords
beta
butoxycarbonylamino
benzoyloxy
tax
acetoxy
Prior art date
Application number
MA23945A
Other languages
English (en)
French (fr)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA23606(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MA23606A1 publication Critical patent/MA23606A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
MA23945A 1994-07-08 1995-07-06 Procede de preparation du trihydrate du (2r, 3s) -3-tert-butoxycarbonylamino -2-hydroxy-3- phenylpropionate de 4-acetoxy-2a- benzoyloxy-5b , 20-epoxy-1.7b, 10b- trihydroxy- 9- oxo-tax-11- en-13 a-yle. MA23606A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9408479A FR2722191B1 (fr) 1994-07-08 1994-07-08 Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle

Publications (1)

Publication Number Publication Date
MA23606A1 true MA23606A1 (fr) 1996-04-01

Family

ID=9465183

Family Applications (1)

Application Number Title Priority Date Filing Date
MA23945A MA23606A1 (fr) 1994-07-08 1995-07-06 Procede de preparation du trihydrate du (2r, 3s) -3-tert-butoxycarbonylamino -2-hydroxy-3- phenylpropionate de 4-acetoxy-2a- benzoyloxy-5b , 20-epoxy-1.7b, 10b- trihydroxy- 9- oxo-tax-11- en-13 a-yle.

Country Status (38)

Country Link
US (1) US6022985A (enEXAMPLES)
EP (1) EP0770070B1 (enEXAMPLES)
JP (1) JP3753155B2 (enEXAMPLES)
KR (1) KR100391753B1 (enEXAMPLES)
CN (1) CN1067996C (enEXAMPLES)
AT (1) ATE171702T1 (enEXAMPLES)
AU (1) AU706519B2 (enEXAMPLES)
BR (1) BR9508789A (enEXAMPLES)
CA (1) CA2193531C (enEXAMPLES)
CO (1) CO4410189A1 (enEXAMPLES)
CZ (1) CZ284695B6 (enEXAMPLES)
DE (1) DE69505128T2 (enEXAMPLES)
DK (1) DK0770070T3 (enEXAMPLES)
DZ (1) DZ1905A1 (enEXAMPLES)
ES (1) ES2121404T3 (enEXAMPLES)
FI (1) FI119246B (enEXAMPLES)
FR (1) FR2722191B1 (enEXAMPLES)
GR (1) GR3027558T3 (enEXAMPLES)
HU (1) HU220634B1 (enEXAMPLES)
IL (1) IL114274A (enEXAMPLES)
IN (1) IN183947B (enEXAMPLES)
IS (1) IS2032B (enEXAMPLES)
MA (1) MA23606A1 (enEXAMPLES)
MX (1) MX9700173A (enEXAMPLES)
MY (1) MY118481A (enEXAMPLES)
NO (1) NO314500B1 (enEXAMPLES)
NZ (1) NZ289455A (enEXAMPLES)
PE (1) PE8697A1 (enEXAMPLES)
PL (1) PL179876B1 (enEXAMPLES)
RU (1) RU2126397C1 (enEXAMPLES)
SI (1) SI0770070T1 (enEXAMPLES)
SK (1) SK280520B6 (enEXAMPLES)
TN (1) TNSN95071A1 (enEXAMPLES)
TW (1) TW419473B (enEXAMPLES)
UA (1) UA51624C2 (enEXAMPLES)
UY (1) UY23991A1 (enEXAMPLES)
WO (1) WO1996001815A1 (enEXAMPLES)
ZA (1) ZA955646B (enEXAMPLES)

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KR20010020342A (ko) 1997-04-28 2001-03-15 자끄 사비나 종양치료용 맥관형성 길항제의 아데노바이러스-매개 종양내 전달방법
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
US6266619B1 (en) * 1999-07-20 2001-07-24 Halliburton Energy Services, Inc. System and method for real time reservoir management
US6853921B2 (en) 1999-07-20 2005-02-08 Halliburton Energy Services, Inc. System and method for real time reservoir management
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
US6891050B2 (en) * 2001-08-10 2005-05-10 Dabur India Limited Process for the preparation of taxanes such as paclitaxel, docetaxel and structurally similar analogs
US6881852B2 (en) * 2002-02-05 2005-04-19 Dabur India Limited Process of purification of paclitaxel and docetaxel
US7247738B2 (en) * 2002-05-07 2007-07-24 Dabur India Limited Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids
US6900342B2 (en) * 2002-05-10 2005-05-31 Dabur India Limited Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
US6838569B2 (en) * 2002-12-16 2005-01-04 Dabur India Limited Process for preparation of paclitaxel trihydrate and docetaxel trihydrate
US7584165B2 (en) * 2003-01-30 2009-09-01 Landmark Graphics Corporation Support apparatus, method and system for real time operations and maintenance
US8703982B2 (en) 2003-03-17 2014-04-22 Phyton Holdings Llc Purification of taxanes
CN1268619C (zh) * 2003-05-08 2006-08-09 上海迪赛诺化学制药有限公司 多烯紫杉醇三水化合物的制备方法
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
US7838551B2 (en) 2003-12-12 2010-11-23 Quiral Quimica do Basil S.A. Process for the preparation of concentrated, sterile injectable solutions containing docetaxel
US7142986B2 (en) * 2005-02-01 2006-11-28 Smith International, Inc. System for optimizing drilling in real time
CN100420681C (zh) * 2005-04-29 2008-09-24 上海奥锐特国际贸易有限公司 多烯紫杉醇三水物的制备方法
CA2620585C (en) 2005-08-31 2015-04-28 Abraxis Bioscience, Llc Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
AU2006284657B2 (en) 2005-08-31 2012-07-19 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
BRPI0606132A2 (pt) * 2005-10-12 2009-06-02 Sicor Inc formas cristalinas de docetaxel e processos para seu preparo
KR100995390B1 (ko) 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
MX2008009308A (es) * 2006-01-20 2008-10-03 Landmark Graphics Corp Administracion del sistema de produccion dinamica.
EP2001874A4 (en) * 2006-03-21 2010-04-07 Reddys Lab Ltd Dr DOCETAXEL POLYMORPH AND CORRESPONDING METHODS
EP2094084A4 (en) * 2006-10-20 2010-01-13 Scinopharm Singapore Pte Ltd PROCESS FOR PREPARING CRYSTALLINE WATER-FREE DOCETAXEL
KR100868116B1 (ko) * 2007-04-09 2008-11-10 한미약품 주식회사 도세탁셀·모노프로필렌글라이콜 내포화합물 및 이의제조방법
KR100878455B1 (ko) * 2007-04-10 2009-01-13 한미약품 주식회사 안정한 무수결정형 도세탁셀 및 이의 제조방법
US20100197944A1 (en) * 2007-07-04 2010-08-05 Dr. Reddy's Laboratories Limited Docetaxel process and polymorphs
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
EP2330100B1 (en) 2009-11-04 2017-01-11 Emcure Pharmaceuticals Limited An improved process for preparation of taxane derivatives
NZ603828A (en) 2010-05-03 2015-09-25 Teikoku Pharma Usa Inc Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
WO2012160568A1 (en) * 2011-05-23 2012-11-29 Shilpa Medicare Limited Process for preparing docetaxel trihydrate polymorph
LT2753355T (lt) 2011-09-08 2019-01-25 New York University Onkolitinis herpes simplex virusas ir jo terapinis panaudojimas
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EA031986B1 (ru) 2012-04-04 2019-03-29 Галозим, Инк. Способ и комбинация для лечения солидной раковой опухоли и набор, содержащий комбинацию
AU2013266243A1 (en) 2012-05-24 2014-12-18 Beth Israel Deaconess Medical Center, Inc. Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer
WO2014014518A1 (en) 2012-07-18 2014-01-23 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
EP2968406A4 (en) 2013-03-14 2016-10-26 Icahn School Med Mount Sinai WITH AUTOLOGOUS TUMORLYSAT-LOADED DENDRITIC CELL VACCINE FOR THE TREATMENT OF LIVER CANCER
WO2015050844A1 (en) 2013-10-01 2015-04-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
US10350264B2 (en) 2014-03-27 2019-07-16 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating NCOA4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
WO2016205429A1 (en) 2015-06-15 2016-12-22 New York University Method of treatment using oncolytic viruses
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FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
EP0770070A1 (fr) 1997-05-02
DK0770070T3 (da) 1999-03-01
NO314500B1 (no) 2003-03-31
US6022985A (en) 2000-02-08
IN183947B (enEXAMPLES) 2000-05-20
FR2722191B1 (fr) 1996-08-23
CA2193531A1 (fr) 1996-01-25
CA2193531C (fr) 2006-12-05
CZ284695B6 (cs) 1999-02-17
RU2126397C1 (ru) 1999-02-20
IS2032B (is) 2005-08-15
NO970007D0 (no) 1997-01-02
JP3753155B2 (ja) 2006-03-08
NZ289455A (en) 1997-12-19
IS4411A (is) 1997-01-07
DZ1905A1 (fr) 2002-02-17
TNSN95071A1 (fr) 1996-02-06
ZA955646B (en) 1996-02-21
PE8697A1 (es) 1997-03-26
EP0770070B1 (fr) 1998-09-30
MY118481A (en) 2004-11-30
PL179876B1 (pl) 2000-11-30
BR9508789A (pt) 1997-10-21
CZ3597A3 (en) 1997-04-16
KR100391753B1 (ko) 2004-02-11
CO4410189A1 (es) 1997-01-09
WO1996001815A1 (fr) 1996-01-25
SK697A3 (en) 1997-06-04
JPH10502627A (ja) 1998-03-10
CN1067996C (zh) 2001-07-04
SK280520B6 (sk) 2000-03-13
KR970704721A (ko) 1997-09-06
UY23991A1 (es) 1995-09-20
NO970007L (no) 1997-01-02
FI119246B (fi) 2008-09-15
HU9700041D0 (en) 1997-02-28
DE69505128D1 (de) 1998-11-05
ATE171702T1 (de) 1998-10-15
DE69505128T2 (de) 1999-04-01
AU706519B2 (en) 1999-06-17
UA51624C2 (uk) 2002-12-16
PL318195A1 (en) 1997-05-26
IL114274A0 (en) 1995-10-31
FI970069A0 (fi) 1997-01-07
HUT76833A (en) 1997-11-28
ES2121404T3 (es) 1998-11-16
AU2930595A (en) 1996-02-09
TW419473B (en) 2001-01-21
CN1151741A (zh) 1997-06-11
GR3027558T3 (en) 1998-11-30
FI970069L (fi) 1997-01-07
FR2722191A1 (fr) 1996-01-12
MX9700173A (es) 1997-04-30
IL114274A (en) 1999-04-11
HU220634B1 (hu) 2002-03-28
SI0770070T1 (en) 1998-12-31

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