FR2456116A1 - Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques - Google Patents

Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques

Info

Publication number
FR2456116A1
FR2456116A1 FR7911964A FR7911964A FR2456116A1 FR 2456116 A1 FR2456116 A1 FR 2456116A1 FR 7911964 A FR7911964 A FR 7911964A FR 7911964 A FR7911964 A FR 7911964A FR 2456116 A1 FR2456116 A1 FR 2456116A1
Authority
FR
France
Prior art keywords
caulophyllogenin
therapeutic applications
saponin
saponin derived
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7911964A
Other languages
English (en)
Other versions
FR2456116B1 (fr
Inventor
Henri Combier
Gisele Prat
Henri Pontagnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda Pharma SAS
Original Assignee
Laboratoires Sarget
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Sarget filed Critical Laboratoires Sarget
Priority to FR7911964A priority Critical patent/FR2456116A1/fr
Priority to DE19803015363 priority patent/DE3015363A1/de
Priority to PT71167A priority patent/PT71167A/pt
Priority to IT21712/80A priority patent/IT1141945B/it
Priority to MA19028A priority patent/MA18832A1/fr
Priority to BE0/200502A priority patent/BE883152A/fr
Priority to NL8002673A priority patent/NL8002673A/nl
Priority to ES491354A priority patent/ES8101626A1/es
Priority to CH367280A priority patent/CH645386A5/fr
Priority to CA000351653A priority patent/CA1148936A/fr
Priority to OA57111A priority patent/OA06531A/fr
Priority to US06/148,932 priority patent/US4335113A/en
Priority to ZA00802829A priority patent/ZA802829B/xx
Publication of FR2456116A1 publication Critical patent/FR2456116A1/fr
Application granted granted Critical
Publication of FR2456116B1 publication Critical patent/FR2456116B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE UNE NOUVELLE SAPONINE TRITERPENIQUE DERIVEES DE LA CAULOPHYLLOGENINE, SON PROCEDE D'EXTRACTION A PARTIR DE VARIETES DE CHRYSANTELLUM ET SON UTILISATION THERAPEUTIQUE. CETTE SAPONINE EST CARACTERISEE COMME ETANT L'ESTER DE LA O-B-D-GLUCOSYL-3B-CAULOPHYLLOGENINE ET D'UN OLIGOSACCHARIDE COMPRENANT DEUX UNITES L-RHAMNOSE ET DEUX UNITES D-XYLOSE. ELLE EST EXTRAITE DU MATERIAU VEGETAL ET PURIFIEE PAR DES TECHNIQUES DE CHROMATOGRAPHIE LIQUIDE PREPARATIVE SOUS PRESSION. CETTE SAPONINE EST UTILE EN THERAPEUTIQUE HUMAINE ET VETERINAIRE EN PHLEBOLOGIE, RHUMATOLOGIE, TRAUMATOLOGIE.
FR7911964A 1979-05-11 1979-05-11 Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques Granted FR2456116A1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR7911964A FR2456116A1 (fr) 1979-05-11 1979-05-11 Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques
DE19803015363 DE3015363A1 (de) 1979-05-11 1980-04-22 Glucosylcaulophyllogeninester, verfahren zu seiner herstellung und diesen enthaltende arzneimittel
PT71167A PT71167A (pt) 1979-05-11 1980-04-29 Procede pour preparer nouvelle saponine triterpenique derivee de la caulophyllogenine et ses application therapeutiques
IT21712/80A IT1141945B (it) 1979-05-11 1980-04-29 Derivato triterpenico di saponina con proprieta' farmacologiche
MA19028A MA18832A1 (fr) 1979-05-11 1980-05-05 Nouvelle saponine triterpenique,son procede d'obtention et son emploi comme medicament
BE0/200502A BE883152A (fr) 1979-05-11 1980-05-07 Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques
NL8002673A NL8002673A (nl) 1979-05-11 1980-05-09 Een nieuw triterpenisch saponine en werkwijze voor het bereiden en toepassen van dit saponine.
ES491354A ES8101626A1 (es) 1979-05-11 1980-05-09 Procedimiento de preparacion, a partir de variedades de chrysanthellum, de una nueva saponina triterpenica
CH367280A CH645386A5 (fr) 1979-05-11 1980-05-09 Saponine, procede pour sa preparation et medicaments contenant cette saponine.
CA000351653A CA1148936A (fr) 1979-05-11 1980-05-09 Saponine triterpenique utilisee en pharmacologie
OA57111A OA06531A (fr) 1979-05-11 1980-05-10 Nouvelle saponine triterpénique et son procédé d'obtention.
US06/148,932 US4335113A (en) 1979-05-11 1980-05-12 Triterpenic saponin having pharmacological potency
ZA00802829A ZA802829B (en) 1979-05-11 1980-05-12 New terpenic saponin, its method of obtaining and its use as medicines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7911964A FR2456116A1 (fr) 1979-05-11 1979-05-11 Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques

Publications (2)

Publication Number Publication Date
FR2456116A1 true FR2456116A1 (fr) 1980-12-05
FR2456116B1 FR2456116B1 (fr) 1982-05-28

Family

ID=9225333

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7911964A Granted FR2456116A1 (fr) 1979-05-11 1979-05-11 Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques

Country Status (13)

Country Link
US (1) US4335113A (fr)
BE (1) BE883152A (fr)
CA (1) CA1148936A (fr)
CH (1) CH645386A5 (fr)
DE (1) DE3015363A1 (fr)
ES (1) ES8101626A1 (fr)
FR (1) FR2456116A1 (fr)
IT (1) IT1141945B (fr)
MA (1) MA18832A1 (fr)
NL (1) NL8002673A (fr)
OA (1) OA06531A (fr)
PT (1) PT71167A (fr)
ZA (1) ZA802829B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579907A1 (en) * 1985-04-09 1986-10-10 Couderc Pierre Method for enriching chrysantellum with active ingredients by physical processes
FR2618071A1 (fr) * 1987-07-17 1989-01-20 Guillot Bernard Compositions cosmetiques et dermatologiques a base d'extraits de chrysanthellum
FR2758085A1 (fr) * 1997-01-09 1998-07-10 Lanatech Composition amincissante incluant un extrait de chrysanthellum indicum
FR2842109A1 (fr) * 2002-07-11 2004-01-16 Sicobel Lab Utilisation d'un extrait de chrysanthellum
EP1687320A1 (fr) * 2003-11-27 2006-08-09 Griffith University Nouveaux composes analgesiques, extraits les contenant et procedes de preparation associe

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501734A (en) * 1981-03-06 1985-02-26 Wakunaga Yakuhin Kabushiki Kaisha Promotion of absorption of drugs administered through the alimentary system
JPS59118053A (ja) * 1982-12-24 1984-07-07 Hayashibara Biochem Lab Inc 飲食物とその製造方法
FR2540707A1 (fr) * 1983-02-16 1984-08-17 Hugues Coffinet Gomme a macher contenant du ginseng
IT1207504B (it) * 1985-09-26 1989-05-25 Crinos Industria Farmaco Composizione moderatrice dell'appetito ed antigastrica.
US5352449A (en) * 1986-05-30 1994-10-04 Cambridge Biotech Corporation Vaccine comprising recombinant feline leukemia antigen and saponin adjuvant
US5166139A (en) * 1987-02-26 1992-11-24 Indena, S.P.A. Complexes of saponins and their aglycons with phospholipids and pharmaceutical and cosmetic compositions containing them
CA1331443C (fr) * 1987-05-29 1994-08-16 Charlotte A. Kensil Adjuvant a saponine
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US5583112A (en) * 1987-05-29 1996-12-10 Cambridge Biotech Corporation Saponin-antigen conjugates and the use thereof
US5650398A (en) * 1992-07-02 1997-07-22 Cambridge Biotech Corporation Drug delivery enhancement via modified saponins
US5273965A (en) * 1992-07-02 1993-12-28 Cambridge Biotech Corporation Methods for enhancing drug delivery with modified saponins
FR2755609B1 (fr) * 1996-11-14 1998-12-24 Lanatech Composition pour la prevention du vieillissement cutane
US6172106B1 (en) 1998-02-09 2001-01-09 R. Armour Forse Sesamol inhibition of Δ-5-desaturase activity and uses therefor
WO1999053933A1 (fr) 1998-04-17 1999-10-28 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agrigulture And Agri-Food Canada Procede de recuperation et de purification de saponines et de sapogenines provenant de quinoa (chenopodium quinoa)
PT1625135E (pt) * 2003-02-27 2009-07-10 Glaxo Group Ltd Composição de fondaparinux sódico de pureza elevada

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378044A1 (fr) * 1977-01-20 1978-08-18 Sarget Lab Nouvel extrait vegetal a partir de varietes de chrysanthellum

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH410283A (de) * 1960-06-14 1966-03-31 Klinge Co Chem Pharm Fab Verfahren zur Gewinnung von genuinem Aescin aus Extrakten der Rosskastanie
US3238190A (en) * 1963-10-23 1966-03-01 Madaus & Co K G Fa Dr Aescin recovery
US3713980A (en) * 1969-11-25 1973-01-30 Merck Patent Gmbh Process for the preparation of peruvoside
US3723410A (en) * 1970-12-01 1973-03-27 Amazon Natural Drug Co Method of producing stevioside
IT1064709B (it) * 1976-07-02 1985-02-25 Snam Progetti Processo di estrazione di composti glucosidici indesiderabili e.o tossici presenti nei vegetali
JPS5338669A (en) * 1976-09-16 1978-04-08 Toyo Soda Mfg Co Ltd Separation of natural sweetening agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378044A1 (fr) * 1977-01-20 1978-08-18 Sarget Lab Nouvel extrait vegetal a partir de varietes de chrysanthellum

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1976 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579907A1 (en) * 1985-04-09 1986-10-10 Couderc Pierre Method for enriching chrysantellum with active ingredients by physical processes
FR2618071A1 (fr) * 1987-07-17 1989-01-20 Guillot Bernard Compositions cosmetiques et dermatologiques a base d'extraits de chrysanthellum
FR2758085A1 (fr) * 1997-01-09 1998-07-10 Lanatech Composition amincissante incluant un extrait de chrysanthellum indicum
WO1998030200A1 (fr) * 1997-01-09 1998-07-16 Lanatech Laboratoire Nature Et Technique Composition cosmetique amincissante incluant un extrait de chrysanthellum indicum
US6001366A (en) * 1997-01-09 1999-12-14 Lanatech Laboratoire Nature Et Technique Slimming cosmetic composition containing a Chrysanthellum indicum extract
FR2842109A1 (fr) * 2002-07-11 2004-01-16 Sicobel Lab Utilisation d'un extrait de chrysanthellum
WO2004006943A2 (fr) * 2002-07-11 2004-01-22 Laboratoire Sicobel Utilisation d'un extrait de chrysanthellum
WO2004006943A3 (fr) * 2002-07-11 2004-04-08 Sicobel Lab Utilisation d'un extrait de chrysanthellum
EP1687320A1 (fr) * 2003-11-27 2006-08-09 Griffith University Nouveaux composes analgesiques, extraits les contenant et procedes de preparation associe
EP1687320A4 (fr) * 2003-11-27 2011-01-19 Univ Griffith Nouveaux composes analgesiques, extraits les contenant et procedes de preparation associe

Also Published As

Publication number Publication date
NL8002673A (nl) 1980-11-13
ES491354A0 (es) 1980-12-16
FR2456116B1 (fr) 1982-05-28
ZA802829B (en) 1981-05-27
ES8101626A1 (es) 1980-12-16
IT8021712A0 (it) 1980-04-29
IT1141945B (it) 1986-10-08
PT71167A (pt) 1980-05-01
BE883152A (fr) 1980-09-01
OA06531A (fr) 1981-07-31
DE3015363C2 (fr) 1988-12-22
CA1148936A (fr) 1983-06-28
US4335113A (en) 1982-06-15
MA18832A1 (fr) 1980-12-31
DE3015363A1 (de) 1980-11-27
CH645386A5 (fr) 1984-09-28

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