DK0770070T3 - Fremgangsmåde til fremstilling af 4-acetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1,7beta,10beta-trihydoxy-9-oxo-tax-11-en-13alfa - Google Patents

Fremgangsmåde til fremstilling af 4-acetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1,7beta,10beta-trihydoxy-9-oxo-tax-11-en-13alfa

Info

Publication number
DK0770070T3
DK0770070T3 DK95925022T DK95925022T DK0770070T3 DK 0770070 T3 DK0770070 T3 DK 0770070T3 DK 95925022 T DK95925022 T DK 95925022T DK 95925022 T DK95925022 T DK 95925022T DK 0770070 T3 DK0770070 T3 DK 0770070T3
Authority
DK
Denmark
Prior art keywords
beta
benzoyloxy
tax
acetoxy
oxo
Prior art date
Application number
DK95925022T
Other languages
Danish (da)
English (en)
Inventor
Jacques Doveze
Elie Fouque
Bernadette Mandard
Isabelle Taillepied
Jean-Rene Authelin
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0770070(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0770070T3 publication Critical patent/DK0770070T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK95925022T 1994-07-08 1995-07-07 Fremgangsmåde til fremstilling af 4-acetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1,7beta,10beta-trihydoxy-9-oxo-tax-11-en-13alfa DK0770070T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9408479A FR2722191B1 (fr) 1994-07-08 1994-07-08 Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
PCT/FR1995/000910 WO1996001815A1 (fr) 1994-07-08 1995-07-07 PROCEDE DE PREPARATION DU TRIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4-ACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1,7β,10β-TRIHYDROXY-9-OXO-TAX-11-EN-13α-YLE

Publications (1)

Publication Number Publication Date
DK0770070T3 true DK0770070T3 (da) 1999-03-01

Family

ID=9465183

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95925022T DK0770070T3 (da) 1994-07-08 1995-07-07 Fremgangsmåde til fremstilling af 4-acetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1,7beta,10beta-trihydoxy-9-oxo-tax-11-en-13alfa

Country Status (38)

Country Link
US (1) US6022985A (enEXAMPLES)
EP (1) EP0770070B1 (enEXAMPLES)
JP (1) JP3753155B2 (enEXAMPLES)
KR (1) KR100391753B1 (enEXAMPLES)
CN (1) CN1067996C (enEXAMPLES)
AT (1) ATE171702T1 (enEXAMPLES)
AU (1) AU706519B2 (enEXAMPLES)
BR (1) BR9508789A (enEXAMPLES)
CA (1) CA2193531C (enEXAMPLES)
CO (1) CO4410189A1 (enEXAMPLES)
CZ (1) CZ284695B6 (enEXAMPLES)
DE (1) DE69505128T2 (enEXAMPLES)
DK (1) DK0770070T3 (enEXAMPLES)
DZ (1) DZ1905A1 (enEXAMPLES)
ES (1) ES2121404T3 (enEXAMPLES)
FI (1) FI119246B (enEXAMPLES)
FR (1) FR2722191B1 (enEXAMPLES)
GR (1) GR3027558T3 (enEXAMPLES)
HU (1) HU220634B1 (enEXAMPLES)
IL (1) IL114274A (enEXAMPLES)
IN (1) IN183947B (enEXAMPLES)
IS (1) IS2032B (enEXAMPLES)
MA (1) MA23606A1 (enEXAMPLES)
MX (1) MX9700173A (enEXAMPLES)
MY (1) MY118481A (enEXAMPLES)
NO (1) NO314500B1 (enEXAMPLES)
NZ (1) NZ289455A (enEXAMPLES)
PE (1) PE8697A1 (enEXAMPLES)
PL (1) PL179876B1 (enEXAMPLES)
RU (1) RU2126397C1 (enEXAMPLES)
SI (1) SI0770070T1 (enEXAMPLES)
SK (1) SK280520B6 (enEXAMPLES)
TN (1) TNSN95071A1 (enEXAMPLES)
TW (1) TW419473B (enEXAMPLES)
UA (1) UA51624C2 (enEXAMPLES)
UY (1) UY23991A1 (enEXAMPLES)
WO (1) WO1996001815A1 (enEXAMPLES)
ZA (1) ZA955646B (enEXAMPLES)

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US6891050B2 (en) * 2001-08-10 2005-05-10 Dabur India Limited Process for the preparation of taxanes such as paclitaxel, docetaxel and structurally similar analogs
US6881852B2 (en) * 2002-02-05 2005-04-19 Dabur India Limited Process of purification of paclitaxel and docetaxel
US7247738B2 (en) * 2002-05-07 2007-07-24 Dabur India Limited Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids
US6900342B2 (en) * 2002-05-10 2005-05-31 Dabur India Limited Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
US6838569B2 (en) * 2002-12-16 2005-01-04 Dabur India Limited Process for preparation of paclitaxel trihydrate and docetaxel trihydrate
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US8703982B2 (en) 2003-03-17 2014-04-22 Phyton Holdings Llc Purification of taxanes
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FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
US7838551B2 (en) 2003-12-12 2010-11-23 Quiral Quimica do Basil S.A. Process for the preparation of concentrated, sterile injectable solutions containing docetaxel
US7142986B2 (en) * 2005-02-01 2006-11-28 Smith International, Inc. System for optimizing drilling in real time
CN100420681C (zh) * 2005-04-29 2008-09-24 上海奥锐特国际贸易有限公司 多烯紫杉醇三水物的制备方法
CA2620585C (en) 2005-08-31 2015-04-28 Abraxis Bioscience, Llc Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
AU2006284657B2 (en) 2005-08-31 2012-07-19 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
BRPI0606132A2 (pt) * 2005-10-12 2009-06-02 Sicor Inc formas cristalinas de docetaxel e processos para seu preparo
KR100995390B1 (ko) 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
MX2008009308A (es) * 2006-01-20 2008-10-03 Landmark Graphics Corp Administracion del sistema de produccion dinamica.
EP2001874A4 (en) * 2006-03-21 2010-04-07 Reddys Lab Ltd Dr DOCETAXEL POLYMORPH AND CORRESPONDING METHODS
EP2094084A4 (en) * 2006-10-20 2010-01-13 Scinopharm Singapore Pte Ltd PROCESS FOR PREPARING CRYSTALLINE WATER-FREE DOCETAXEL
KR100868116B1 (ko) * 2007-04-09 2008-11-10 한미약품 주식회사 도세탁셀·모노프로필렌글라이콜 내포화합물 및 이의제조방법
KR100878455B1 (ko) * 2007-04-10 2009-01-13 한미약품 주식회사 안정한 무수결정형 도세탁셀 및 이의 제조방법
US20100197944A1 (en) * 2007-07-04 2010-08-05 Dr. Reddy's Laboratories Limited Docetaxel process and polymorphs
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PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
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FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
EP0770070A1 (fr) 1997-05-02
MA23606A1 (fr) 1996-04-01
NO314500B1 (no) 2003-03-31
US6022985A (en) 2000-02-08
IN183947B (enEXAMPLES) 2000-05-20
FR2722191B1 (fr) 1996-08-23
CA2193531A1 (fr) 1996-01-25
CA2193531C (fr) 2006-12-05
CZ284695B6 (cs) 1999-02-17
RU2126397C1 (ru) 1999-02-20
IS2032B (is) 2005-08-15
NO970007D0 (no) 1997-01-02
JP3753155B2 (ja) 2006-03-08
NZ289455A (en) 1997-12-19
IS4411A (is) 1997-01-07
DZ1905A1 (fr) 2002-02-17
TNSN95071A1 (fr) 1996-02-06
ZA955646B (en) 1996-02-21
PE8697A1 (es) 1997-03-26
EP0770070B1 (fr) 1998-09-30
MY118481A (en) 2004-11-30
PL179876B1 (pl) 2000-11-30
BR9508789A (pt) 1997-10-21
CZ3597A3 (en) 1997-04-16
KR100391753B1 (ko) 2004-02-11
CO4410189A1 (es) 1997-01-09
WO1996001815A1 (fr) 1996-01-25
SK697A3 (en) 1997-06-04
JPH10502627A (ja) 1998-03-10
CN1067996C (zh) 2001-07-04
SK280520B6 (sk) 2000-03-13
KR970704721A (ko) 1997-09-06
UY23991A1 (es) 1995-09-20
NO970007L (no) 1997-01-02
FI119246B (fi) 2008-09-15
HU9700041D0 (en) 1997-02-28
DE69505128D1 (de) 1998-11-05
ATE171702T1 (de) 1998-10-15
DE69505128T2 (de) 1999-04-01
AU706519B2 (en) 1999-06-17
UA51624C2 (uk) 2002-12-16
PL318195A1 (en) 1997-05-26
IL114274A0 (en) 1995-10-31
FI970069A0 (fi) 1997-01-07
HUT76833A (en) 1997-11-28
ES2121404T3 (es) 1998-11-16
AU2930595A (en) 1996-02-09
TW419473B (en) 2001-01-21
CN1151741A (zh) 1997-06-11
GR3027558T3 (en) 1998-11-30
FI970069L (fi) 1997-01-07
FR2722191A1 (fr) 1996-01-12
MX9700173A (es) 1997-04-30
IL114274A (en) 1999-04-11
HU220634B1 (hu) 2002-03-28
SI0770070T1 (en) 1998-12-31

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