NO970007L - Fremgangsmåte for fremstilling av 4-acetoksy-2<alfa>-benzoyloksy-5<beta>, 20-epoksy-1, 7<beta>, 10<beta>-trihydroksy-9-okso-tax-11-en-13<alfa>-yl (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenyl-propionat trihydrat - Google Patents

Fremgangsmåte for fremstilling av 4-acetoksy-2<alfa>-benzoyloksy-5<beta>, 20-epoksy-1, 7<beta>, 10<beta>-trihydroksy-9-okso-tax-11-en-13<alfa>-yl (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenyl-propionat trihydrat

Info

Publication number
NO970007L
NO970007L NO970007A NO970007A NO970007L NO 970007 L NO970007 L NO 970007L NO 970007 A NO970007 A NO 970007A NO 970007 A NO970007 A NO 970007A NO 970007 L NO970007 L NO 970007L
Authority
NO
Norway
Prior art keywords
beta
alpha
hydroxy
butoxycarbonylamino
benzoyloxy
Prior art date
Application number
NO970007A
Other languages
English (en)
Other versions
NO970007D0 (no
NO314500B1 (no
Inventor
Jean-Rene Authelin
Jaques Doveze
Elie Fouque
Bernadette Mandard
Isabelle Taillepied
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO970007(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO970007D0 publication Critical patent/NO970007D0/no
Publication of NO970007L publication Critical patent/NO970007L/no
Publication of NO314500B1 publication Critical patent/NO314500B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
NO19970007A 1994-07-08 1997-01-02 Fremgangsmåte for fremstilling av 4-acetoksy-2<alfa>- benzoyloksy-5<beta>, 20-epoksy-1, 7<beta>, 10<beta>-trihydroksy-9-okso-tax-11-en-13<alfa>-yl (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylpropionat trihydrat NO314500B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9408479A FR2722191B1 (fr) 1994-07-08 1994-07-08 Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
PCT/FR1995/000910 WO1996001815A1 (fr) 1994-07-08 1995-07-07 PROCEDE DE PREPARATION DU TRIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4-ACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1,7β,10β-TRIHYDROXY-9-OXO-TAX-11-EN-13α-YLE

Publications (3)

Publication Number Publication Date
NO970007D0 NO970007D0 (no) 1997-01-02
NO970007L true NO970007L (no) 1997-01-02
NO314500B1 NO314500B1 (no) 2003-03-31

Family

ID=9465183

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970007A NO314500B1 (no) 1994-07-08 1997-01-02 Fremgangsmåte for fremstilling av 4-acetoksy-2<alfa>- benzoyloksy-5<beta>, 20-epoksy-1, 7<beta>, 10<beta>-trihydroksy-9-okso-tax-11-en-13<alfa>-yl (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylpropionat trihydrat

Country Status (38)

Country Link
US (1) US6022985A (no)
EP (1) EP0770070B1 (no)
JP (1) JP3753155B2 (no)
KR (1) KR100391753B1 (no)
CN (1) CN1067996C (no)
AT (1) ATE171702T1 (no)
AU (1) AU706519B2 (no)
BR (1) BR9508789A (no)
CA (1) CA2193531C (no)
CO (1) CO4410189A1 (no)
CZ (1) CZ284695B6 (no)
DE (1) DE69505128T2 (no)
DK (1) DK0770070T3 (no)
DZ (1) DZ1905A1 (no)
ES (1) ES2121404T3 (no)
FI (1) FI119246B (no)
FR (1) FR2722191B1 (no)
GR (1) GR3027558T3 (no)
HU (1) HU220634B1 (no)
IL (1) IL114274A (no)
IN (1) IN183947B (no)
IS (1) IS2032B (no)
MA (1) MA23606A1 (no)
MX (1) MX9700173A (no)
MY (1) MY118481A (no)
NO (1) NO314500B1 (no)
NZ (1) NZ289455A (no)
PE (1) PE8697A1 (no)
PL (1) PL179876B1 (no)
RU (1) RU2126397C1 (no)
SI (1) SI0770070T1 (no)
SK (1) SK280520B6 (no)
TN (1) TNSN95071A1 (no)
TW (1) TW419473B (no)
UA (1) UA51624C2 (no)
UY (1) UY23991A1 (no)
WO (1) WO1996001815A1 (no)
ZA (1) ZA955646B (no)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1177934C (zh) 1997-04-28 2004-12-01 阿文蒂斯药物股份有限公司 腺病毒介导的肿瘤内投送血管生成拮抗剂用于肿瘤的治疗
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
US6266619B1 (en) * 1999-07-20 2001-07-24 Halliburton Energy Services, Inc. System and method for real time reservoir management
US6853921B2 (en) 1999-07-20 2005-02-08 Halliburton Energy Services, Inc. System and method for real time reservoir management
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
US6891050B2 (en) * 2001-08-10 2005-05-10 Dabur India Limited Process for the preparation of taxanes such as paclitaxel, docetaxel and structurally similar analogs
US6881852B2 (en) * 2002-02-05 2005-04-19 Dabur India Limited Process of purification of paclitaxel and docetaxel
US7247738B2 (en) * 2002-05-07 2007-07-24 Dabur India Limited Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids
US6900342B2 (en) * 2002-05-10 2005-05-31 Dabur India Limited Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof
US6838569B2 (en) * 2002-12-16 2005-01-04 Dabur India Limited Process for preparation of paclitaxel trihydrate and docetaxel trihydrate
US7584165B2 (en) * 2003-01-30 2009-09-01 Landmark Graphics Corporation Support apparatus, method and system for real time operations and maintenance
US8703982B2 (en) * 2003-03-17 2014-04-22 Phyton Holdings Llc Purification of taxanes
CN1268619C (zh) * 2003-05-08 2006-08-09 上海迪赛诺化学制药有限公司 多烯紫杉醇三水化合物的制备方法
ES2325506T3 (es) 2003-12-12 2009-09-07 Quiral Quimica Do Brasil Procedimiento para la preparacion de principios activos farmaceuticos (api) anhidros e hidratados; composiciones farmaceuticas estables preparadas a partir de los mismos y usos de dichas composiciones.
US7142986B2 (en) * 2005-02-01 2006-11-28 Smith International, Inc. System for optimizing drilling in real time
CN100420681C (zh) * 2005-04-29 2008-09-24 上海奥锐特国际贸易有限公司 多烯紫杉醇三水物的制备方法
ES2719093T3 (es) * 2005-08-31 2019-07-08 Abraxis Bioscience Llc Composiciones de fármacos poco solubles en agua con mayor estabilidad y métodos para su preparación
TR200801336T1 (tr) * 2005-08-31 2008-08-21 Abraxis Bioscience, Inc. Kararlılığı artmış zayıf su çöznurluğune sahip ilaçların preparasyonuna yönelik kompozisyonlar ve yöntemler.
BRPI0606132A2 (pt) * 2005-10-12 2009-06-02 Sicor Inc formas cristalinas de docetaxel e processos para seu preparo
KR100995390B1 (ko) 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
CN101371164A (zh) * 2006-01-20 2009-02-18 界标制图有限公司 动态生产系统管理
US20100160653A1 (en) * 2006-03-21 2010-06-24 Dr. Reddy's Laboratories Ltd. Docetaxel polymorphs and processes
NZ576355A (en) * 2006-10-20 2012-04-27 Scinopharm Singapore Pte Ltd Process for making crystalline anhydrous docetaxel
KR100868116B1 (ko) * 2007-04-09 2008-11-10 한미약품 주식회사 도세탁셀·모노프로필렌글라이콜 내포화합물 및 이의제조방법
KR100878455B1 (ko) * 2007-04-10 2009-01-13 한미약품 주식회사 안정한 무수결정형 도세탁셀 및 이의 제조방법
WO2009006590A2 (en) * 2007-07-04 2009-01-08 Dr. Reddy's Laboratories Ltd. Docetaxel process and polymorphs
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
EP2080764B1 (en) * 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
ES2621613T3 (es) 2009-11-04 2017-07-04 Emcure Pharmaceuticals Limited Un proceso mejorado para la preparación de derivados de taxano
BR112012028037A2 (pt) 2010-05-03 2016-08-02 Teikoku Pharma Usa Inc formulação de pró-emulsão líquida de taxano não aquosa, métodos para administrar um taxano a um paciente e para fabricar uma formulação de pró-emulsão de taxano, composição de emulsão de taxano, e, kit
WO2012160568A1 (en) * 2011-05-23 2012-11-29 Shilpa Medicare Limited Process for preparing docetaxel trihydrate polymorph
PT2753355T (pt) 2011-09-08 2019-02-01 Univ New York Vírus herpes simplex oncolítico e suas utilizações terapêuticas
WO2013096455A1 (en) 2011-12-20 2013-06-27 Dana-Farber Cancer Institute, Inc. Methods for diagnosing and treating oncogenic kras-associated cancer
WO2013151774A1 (en) 2012-04-04 2013-10-10 Halozyme, Inc. Combination therapy with an anti - hyaluronan agent and a tumor - targeted taxane
US10138479B2 (en) 2012-05-24 2018-11-27 Dana-Farber Cancer Institute, Inc. Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer
US20150285802A1 (en) 2012-07-18 2015-10-08 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US10238723B2 (en) 2013-03-14 2019-03-26 Icahn School Of Medicine At Mount Sinai Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
US10130590B2 (en) 2013-10-01 2018-11-20 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
US10350264B2 (en) 2014-03-27 2019-07-16 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating NCOA4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
EP3307330B1 (en) 2015-06-15 2021-03-10 New York University Method of treatment using oncolytic viruses
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
PL318195A1 (en) 1997-05-26
DE69505128T2 (de) 1999-04-01
DZ1905A1 (fr) 2002-02-17
NO970007D0 (no) 1997-01-02
MY118481A (en) 2004-11-30
KR970704721A (ko) 1997-09-06
MX9700173A (es) 1997-04-30
UY23991A1 (es) 1995-09-20
RU2126397C1 (ru) 1999-02-20
CA2193531A1 (fr) 1996-01-25
ZA955646B (en) 1996-02-21
CN1067996C (zh) 2001-07-04
TNSN95071A1 (fr) 1996-02-06
IS2032B (is) 2005-08-15
SK280520B6 (sk) 2000-03-13
IN183947B (no) 2000-05-20
HU220634B1 (hu) 2002-03-28
FI970069A0 (fi) 1997-01-07
US6022985A (en) 2000-02-08
EP0770070A1 (fr) 1997-05-02
CN1151741A (zh) 1997-06-11
EP0770070B1 (fr) 1998-09-30
MA23606A1 (fr) 1996-04-01
NO314500B1 (no) 2003-03-31
SK697A3 (en) 1997-06-04
ATE171702T1 (de) 1998-10-15
HU9700041D0 (en) 1997-02-28
AU2930595A (en) 1996-02-09
FI970069A (fi) 1997-01-07
GR3027558T3 (en) 1998-11-30
AU706519B2 (en) 1999-06-17
FR2722191A1 (fr) 1996-01-12
IL114274A (en) 1999-04-11
PE8697A1 (es) 1997-03-26
JP3753155B2 (ja) 2006-03-08
CA2193531C (fr) 2006-12-05
DE69505128D1 (de) 1998-11-05
IL114274A0 (en) 1995-10-31
WO1996001815A1 (fr) 1996-01-25
FR2722191B1 (fr) 1996-08-23
IS4411A (is) 1997-01-07
NZ289455A (en) 1997-12-19
KR100391753B1 (ko) 2004-02-11
DK0770070T3 (da) 1999-03-01
FI119246B (fi) 2008-09-15
CO4410189A1 (es) 1997-01-09
ES2121404T3 (es) 1998-11-16
UA51624C2 (uk) 2002-12-16
CZ284695B6 (cs) 1999-02-17
BR9508789A (pt) 1997-10-21
HUT76833A (en) 1997-11-28
CZ3597A3 (en) 1997-04-16
SI0770070T1 (en) 1998-12-31
JPH10502627A (ja) 1998-03-10
TW419473B (en) 2001-01-21
PL179876B1 (pl) 2000-11-30

Similar Documents

Publication Publication Date Title
NO970007D0 (no) Fremgangsmåte for fremstilling av 4-acetoksy-2&lt;alfa&gt;-benzoyloksy-5&lt;beta&gt;, 20-epoksy-1, 7&lt;beta&gt;, 10&lt;beta&gt;-trihydroksy-9-okso-tax-11-en-13&lt;alfa&gt;-yl (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenyl-propionat trihydrat
DE69120500D1 (de) Azasteroide zur Behandlung prostatischer Hypertrophie, ihre Herstellung und Verwendung
IL77010A0 (en) Fatty acid esters,process for the preparation thereof and cosmetic preparations containing the same
BE875142A (fr) Compositions anaerobies stabilisees contenant des acides
IE822442L (en) Diesel fuel fibre felt production
DE3061749D1 (en) Allethrolone derivatives and process for their preparation
ES2120055T3 (es) Procedimiento para la obtencion biotecnologica de alcoholes, aldehidos y acidos carboxilicos.
ATE53011T1 (de) Herstellung von chlorothalonyl.
PL310207A1 (en) Nisatidin containing pharmaceutical agent, method of obtaining nisatidin in its specific form and specific form of nisatidin as such
FR2705959B1 (fr) Procédé de synthèse stéréospécifique de leucotriène B4 sous sa configuration 6Z, 8E, 10E et produits intermédiaires.
ES477163A1 (es) Procedimiento para la preparacion de compuestos de acidos 4-(8x-6,11-dihidro-dibenzo- b.e. -tiepin-11-on-3-il)-4-oxobu- tiricos.
EP0345719A3 (en) Compounds containing at least three functional ester groups, and process for their preparation
JPS5432457A (en) Preparation of 2-alkyl-3-hydroxycyclo-pentylacetic acid esters and perfume composition containing the same
ES332787A3 (es) Procedimiento de produccion de acido l-glutamico.
ES474071A2 (es) Procedimiento para la preparacion de 2-(2&#39;2&#39;2&#39;-trihalogene- til)-4-halogenciclobutan 1 ona
RU95116993A (ru) Способ отбеливания глиносодержащего керамического сырья
DK0549593T3 (da) Fremgangsmåde til racemicering af ikke-racemisk 3-oxocyclopentancarboxylsyre eller hexancarboxylsyre eller estere heraf med C1-C6-alkoholer

Legal Events

Date Code Title Description
MK1K Patent expired