LV10181B - A nicotine containing stimulant unit - Google Patents
A nicotine containing stimulant unit Download PDFInfo
- Publication number
- LV10181B LV10181B LVP-92-552A LV920552A LV10181B LV 10181 B LV10181 B LV 10181B LV 920552 A LV920552 A LV 920552A LV 10181 B LV10181 B LV 10181B
- Authority
- LV
- Latvia
- Prior art keywords
- nicotine
- water
- composition according
- mixture
- stimulant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
- A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Addiction (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Peptides Or Proteins (AREA)
- Manufacture Of Tobacco Products (AREA)
Claims (15)
- LV 10181 NIKOTĪNU SATUROŠS STIMULĒJOŠS SASTĀVS 5 PATENTA FORMULA 1. Siekalās šķīstošs stimulējošs sastāvs, kas satur aktīvu ingredientu un, pēc izvēles, ingredientus, kas satur gēlā ieslēgtas garšas un smaržas piedevas, kas iegūtas ar ūdeni saistošu gēlu 10 veidojošu aģentu, kurā aktīvais ingredients satur nikotīnu vai citus alkaloīdus ar tieši tādu pašu aktivitāti, minētam sastāvam ir i) tekstūras profils, kas noteikts ar tekstūras profila analīzi ar parametru rādītājiem sekojošās robežās : 15 a) izturība, t. i. modulis, lielāks kā 100 N/cm^; b) cietība, t. i. maksimālais spēks, kas pielikts pirmā saspiešanas ciklā, lielāks kā 5N/cm2; c) trauslums, t. i. deformācija procentos, kas vajadzīga, lai sagrautu gēlu, vismaz 30 %; 20 d) adhēzijas spēja, t. i. attiecība starp negatīvā pīķa laukumu starp diviem saspiešanas cikliem un pirmā pīķa laukumu, no 0 līdz 70 %; e) elastība, t. i. attiecība 100 x (D - d) / D, kur D ir parauga augstums (cm) pirms pirmā saspiešanas cikla, 25 un d ir parauga paliekošā deformācija (cm) pirms otra saspiešanas cikla, robežās no 25 līdz 100 %; f) kohēzijas spēja, t. i. kopējā darba attiecība starp pirmo un otro saspiešanas ciklu, robežās no 25 līdz 100 %; 30 ii) dezintegrācijas laiks, kas noteikts pie 37 °C, izmantojot dezintegrācijas testa aparātus atbilstoši Ph. Eur. otram izdevumam, robežās 5-60 minūtes; un 2 iii) nikotīna saturs no 0.5 līdz 10 mg vai tāda paša alkaloīda atbilstošs saturs.
- 2. Stimulējošs sastāvs, saskaņā ar 1. punktu, atšķirīgs ar to, 5 ka tekstūras profilam ir parametru rādītāji sekojošās robežās : a) izturība lielāka kā 200 N/cm^; b) cietība lielāka kā 25 N/cm^; c) trauslums vismaz 30 %; d) adhēzijas spēja no 0 līdz 40%; 10 e) elastība robežās no 50 līdz 100 %; f) kohēzijas spēja robežās no 40 līdz 100 %; un, ka dezintegrācijas laiks ir robežās 6 - 45 minūtes.
- 3. Stimulējošs sastāvs, saskaņā ar 1. un 2. punktiem, 15 atšķirīgs ar to, ka tekstūras profilam ir parametru rādītāji sekojošās robežās: a) izturība lielāka kā 400 N/cm^; b) cietība no 80 līdz 300 N/cm^; c) trauslums vismaz 30 %; 20 d) adhēzijas spēja no 0 līdz 20 %; e) elastība robežās no 80 līdz' 100 %; 0 kohēzijas spēja robežās no 40 līdz 100 %; un, ka dezintegrācijas laiks ir robežās 15 - 40 minūtes.
- 4. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. - 3. punktiem, atšķirīgs ar to, ka gēlu veidojošais aģents satur želatīnu vai vienu vai vairākus sintētiskus vai dabīgus polisaharidus, labāk polisaharīdus, ko izmanto konditorejas produktu ražošanā.
- 5. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. - 3. punktiem, atšķirīgs ar to, ka gēlu veidojošais aģents ir izvēlēts no grupas, kas satur agaru, algīnu, karagēnu (carrageenan), guāra (guar) sveķus, gumiarābiku, gata (ghatti) sveķus, astragāla (tragacanth) sveķus, karaija (karaya) sveķus, robinījas (locust) 35 sēklu sveķus, pektīnu, ksantāna (xanthan) sveķus, šajā gadījuma gumiarabiku un karagēnu (carrageenan), labāk gumiarābiku.
- 6. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. - 5. punktiem, atšķirīgs ar to, ka garšas un smaržas piedevas satur vienu vai vairākus sintētiskus vai dabīgus garšas aģentus, kas izvēlēti no ēteriskām eļļām, esencēm, augļu sulām, un pulveriem, miltiem vai sasmalcināta augu materiāla, ieskaitot tabaku, kafiju, tēju un piparmētru.
- 7. Stimulējošs sastāvs saskaņā ar jebkuru no 1. - 6. punktiem, atšķirīgs ar to, ka piedevas satur vienu vai vairākus vitamīnus vai minerālus.
- 8. Stimulējošs sastāvs saskaņā ar jebkuru no 1. - 7. punktiem, atšķirīgs ar to, ka piedevas satur fizioloģiski saderīgu bufervielu vai aģentu.
- 9. Stimulējošs sastāvs saskaņā ar 8. punktu, atšķirīgs ar to, ka bufervielu vai aģentu un tā daudzumu izvēlas, lai, dezintegrējot sastāvu, nodrošinātu siekalās pH 8 -10.
- 10. Stimulējošs sastāvs saskaņā ar jebkuru no 8. - 9. punktiem, atšķirīgs ar to, ka bufervielas vai aģenta daudzums sastāvā ir no 5 mg līdz 50 mg.
- 11. Stimulējošs sastāvs, saskaņā ar jebkuru no 8. -10. punktiem, atšķirīgs ar to, ka buferviela vai aģents ietver sārmu metālu karbonātus, bikarbonātus, fosfātus, un/vai hidrogenfosfatus.
- 12. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. -11. punktiem, atšķirīgs ar to, ka tas satur nikotīna daudzumu, kas izvēlēts robežās no 0,5 līdz 5.0 mg nikotīna, labāk robežās no 1.0 līdz 1.5 mg, no 1.5 līdz 2.5 mg, vai no 2.5 līdz 3.0 mg nikotīna, lai nodrošinātu vajadzīgo nikotīna stimulēšanu. 4
- 13. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. -12. punktiem, atšķirīgs ar to, ka būtībā stabila nikotīna izdalīšana ir nodrošināta ar vienmērīgu nikotīna sadalījumu sastāvā. 5
- 14. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. -12. punktiem, atšķirīgs ar to, ka izdalīšanās, kas ietver sākuma un uzturošu izdalīšanos, pakāpeniska izmainīšanās ir nodrošināta ar nikotīna strukturāli neviendabīgu sadalījumu daudzslāņainā 10 sastāvā.
- 15. Stimulējošs sastāvs, saskaņā ar jebkuru no 1. -14. punktiem, atšķirīgs ar to, ka tas ir noformēts tādā veidā, kas ir piemērots, lai pieliptu pie aukslējām.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK556089A DK556089D0 (da) | 1989-11-07 | 1989-11-07 | Ryge supplement eller rygeerstatningsprodukt |
| DK615689A DK615689A (da) | 1989-11-07 | 1989-12-04 | Rygesupplement eller rygeerstatningsprodukt |
| PCT/DK1990/000280 WO1991006288A1 (en) | 1989-11-07 | 1990-11-06 | A nicotine containing stimulant unit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV10181A LV10181A (lv) | 1994-10-20 |
| LV10181B true LV10181B (en) | 1995-04-20 |
Family
ID=26067888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-92-552A LV10181B (en) | 1989-11-07 | 1992-12-29 | A nicotine containing stimulant unit |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0500658B1 (lv) |
| JP (2) | JP2958663B2 (lv) |
| KR (1) | KR0154341B1 (lv) |
| AT (1) | ATE100707T1 (lv) |
| AU (1) | AU648522B2 (lv) |
| BR (1) | BR9007821A (lv) |
| CA (1) | CA2073055C (lv) |
| DE (1) | DE69006363T2 (lv) |
| DK (2) | DK615689A (lv) |
| ES (1) | ES2048510T3 (lv) |
| FI (1) | FI101599B1 (lv) |
| HU (2) | HUT62783A (lv) |
| IE (1) | IE62388B1 (lv) |
| LV (1) | LV10181B (lv) |
| NO (1) | NO177082C (lv) |
| NZ (1) | NZ235988A (lv) |
| PT (1) | PT95813B (lv) |
| WO (1) | WO1991006288A1 (lv) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5783207A (en) * | 1985-05-01 | 1998-07-21 | University Of Utah Research Foundation | Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine |
| US5824334A (en) * | 1989-09-05 | 1998-10-20 | University Of Utah Research Foundation | Tobacco substitute |
| GB2299756A (en) * | 1995-03-29 | 1996-10-16 | Gilbert Falkingham Clayton | Gelatinous pastille containing nicotine |
| US6082370A (en) * | 1998-02-09 | 2000-07-04 | Rousseau Research, Inc. | Cigarette with dry powered Vitamin E |
| SE0103211D0 (sv) * | 2001-09-27 | 2001-09-27 | Pharmacia Ab | New formulations and use thereof |
| KR100443722B1 (ko) * | 2002-09-26 | 2004-08-09 | 이용원 | 니코틴을 함유한 하드츄잉캔디 및 그의 제조방법 |
| ES2285233T3 (es) | 2002-12-20 | 2007-11-16 | Niconovum Ab | Un material en particulas que contiene nicotina y celulosa microcristalina fisicamente y quimicamente estable. |
| GB0320854D0 (en) * | 2003-09-05 | 2003-10-08 | Arrow No 7 Ltd | Buccal drug delivery |
| CA2576344C (en) * | 2004-08-11 | 2010-10-05 | Cadbury Adams Usa Llc | Warming compositions and delivery systems therefor |
| SE527323C2 (sv) * | 2004-11-11 | 2006-02-07 | Mahmood Valadi | Cigarett |
| GB0501655D0 (en) * | 2005-01-26 | 2005-03-02 | Veritron Ltd | Therapeutic use |
| WO2007104573A2 (en) | 2006-03-16 | 2007-09-20 | Niconovum Ab | Improved snuff composition |
| US9032971B2 (en) | 2006-11-15 | 2015-05-19 | Philip Morris Usa Inc. | Moist tobacco product and method of making |
| PT2361081T (pt) * | 2008-10-14 | 2016-09-05 | Mcneil Ab | Forma de dosagem intra-oral multiporção e seu uso |
| US9687023B2 (en) | 2009-10-09 | 2017-06-27 | Philip Morris Usa Inc. | Moist smokeless tobacco product for oral usage having on a portion of the outer surface at least one friction reducing strip that provides texture during use |
| JP5845194B2 (ja) * | 2010-02-18 | 2016-01-20 | サッカー・ジャティン・ヴァサントＴＨＡＫＫＡＲ， Ｊａｔｉｎ Ｖａｓａｎｔ | ニコチン含有ソフトゼラチントローチ |
| US9775376B2 (en) | 2010-12-01 | 2017-10-03 | R.J. Reynolds Tobacco Company | Smokeless tobacco pastille and moulding process for forming smokeless tobacco products |
| US20140044857A1 (en) * | 2011-03-02 | 2014-02-13 | Feellife Bioscience International Co., Ltd. | Method for Preparing Water-Soluble Tobacco Flavor in Gel State |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| GB2542192A (en) * | 2015-09-11 | 2017-03-15 | Revolymer (Uk) Ltd | Chewable medicament |
| US20180199617A1 (en) * | 2017-01-18 | 2018-07-19 | Bianca Iodice | Tobacco Free Hookah Smoking Gel |
| CN108693029A (zh) * | 2018-04-09 | 2018-10-23 | 上海烟草集团有限责任公司 | 一种利用物性测试仪测试再造烟叶弹性的方法 |
| US20210169784A1 (en) * | 2019-12-09 | 2021-06-10 | Nicoventures Trading Limited | Buffered oral compositions |
| CN113197327B (zh) * | 2021-05-13 | 2022-11-04 | 云南中烟工业有限责任公司 | 基于长链烷基二元脂肪酸尼古丁盐胶凝剂的凝胶 |
| EP4371421A1 (en) | 2022-11-18 | 2024-05-22 | JT International SA | A nicotine pouch product container, and a method of consuming nicotine pouch products therein |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58128314A (ja) * | 1982-01-26 | 1983-07-30 | Nitto Electric Ind Co Ltd | 粘膜製剤 |
| GB2142822B (en) * | 1983-06-29 | 1987-02-11 | Alec Stanley Walter Shaw | Nicotine lozenges |
| GB8317576D0 (en) * | 1983-06-29 | 1983-08-03 | Shaw A S W | Consumer tobacco products |
| JPS60142927A (ja) * | 1983-12-28 | 1985-07-29 | Lion Corp | 医療用バンド |
| JPS61122211A (ja) * | 1984-11-20 | 1986-06-10 | Mitsubishi Acetate Co Ltd | 口腔粘膜用徐放性付着剤 |
| US4774093A (en) * | 1985-06-25 | 1988-09-27 | Fmc Corporation | Polysaccharide compositions, preparation and uses |
| JPH072632B2 (ja) * | 1985-12-16 | 1995-01-18 | ニチバン株式会社 | 口腔粘膜付着用錠剤 |
| AU579282B2 (en) * | 1986-06-06 | 1988-11-17 | National Starch & Chemical Corporation | Starch-based jelly gum confections |
| GB8615676D0 (en) * | 1986-06-26 | 1986-07-30 | Stoppers Co Ltd | Nicotine containing lozenge |
-
1989
- 1989-12-04 DK DK615689A patent/DK615689A/da not_active Application Discontinuation
-
1990
- 1990-11-06 CA CA002073055A patent/CA2073055C/en not_active Expired - Lifetime
- 1990-11-06 KR KR1019920701074A patent/KR0154341B1/ko not_active IP Right Cessation
- 1990-11-06 IE IE399590A patent/IE62388B1/en not_active IP Right Cessation
- 1990-11-06 ES ES90916715T patent/ES2048510T3/es not_active Expired - Lifetime
- 1990-11-06 WO PCT/DK1990/000280 patent/WO1991006288A1/en active IP Right Grant
- 1990-11-06 DK DK90916715.7T patent/DK0500658T3/da active
- 1990-11-06 JP JP2515318A patent/JP2958663B2/ja not_active Expired - Lifetime
- 1990-11-06 EP EP90916715A patent/EP0500658B1/en not_active Expired - Lifetime
- 1990-11-06 HU HU9201521A patent/HUT62783A/hu unknown
- 1990-11-06 AU AU67254/90A patent/AU648522B2/en not_active Expired
- 1990-11-06 BR BR909007821A patent/BR9007821A/pt not_active Application Discontinuation
- 1990-11-06 DE DE69006363T patent/DE69006363T2/de not_active Expired - Lifetime
- 1990-11-06 AT AT90916715T patent/ATE100707T1/de not_active IP Right Cessation
- 1990-11-07 PT PT95813A patent/PT95813B/pt not_active IP Right Cessation
- 1990-11-07 NZ NZ235988A patent/NZ235988A/xx unknown
-
1992
- 1992-05-06 NO NO921791A patent/NO177082C/no not_active IP Right Cessation
- 1992-05-06 HU HU9201521A patent/HU9201521D0/hu unknown
- 1992-05-07 FI FI922066A patent/FI101599B1/fi active
- 1992-12-29 LV LVP-92-552A patent/LV10181B/en unknown
-
1999
- 1999-03-01 JP JP05273499A patent/JP3357618B2/ja not_active Expired - Fee Related
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