LU84562A1 - 2-(4-((4,4-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyridines - Google Patents
2-(4-((4,4-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyridines Download PDFInfo
- Publication number
- LU84562A1 LU84562A1 LU84562A LU84562A LU84562A1 LU 84562 A1 LU84562 A1 LU 84562A1 LU 84562 A LU84562 A LU 84562A LU 84562 A LU84562 A LU 84562A LU 84562 A1 LU84562 A1 LU 84562A1
- Authority
- LU
- Luxembourg
- Prior art keywords
- formula
- piperazinyl
- addition salts
- butyl
- dioxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33468981 | 1981-12-28 | ||
US06/334,689 US4361565A (en) | 1981-12-28 | 1981-12-28 | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
Publications (1)
Publication Number | Publication Date |
---|---|
LU84562A1 true LU84562A1 (fr) | 1983-09-08 |
Family
ID=23308356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU84562A LU84562A1 (fr) | 1981-12-28 | 1982-12-29 | 2-(4-((4,4-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyridines |
Country Status (27)
Country | Link |
---|---|
US (1) | US4361565A (xx) |
JP (1) | JPS58118583A (xx) |
KR (1) | KR880002011B1 (xx) |
AT (1) | AT380880B (xx) |
AU (1) | AU560667B2 (xx) |
BE (1) | BE895505A (xx) |
CA (1) | CA1237722A (xx) |
CH (1) | CH653682A5 (xx) |
CY (1) | CY1378A (xx) |
DE (1) | DE3248138A1 (xx) |
DK (1) | DK162284C (xx) |
ES (1) | ES8402832A1 (xx) |
FI (1) | FI70892C (xx) |
FR (1) | FR2518994B1 (xx) |
GB (1) | GB2114121B (xx) |
GR (1) | GR77101B (xx) |
HK (1) | HK5188A (xx) |
HU (1) | HU190827B (xx) |
IE (1) | IE54620B1 (xx) |
IT (1) | IT1158040B (xx) |
KE (1) | KE3714A (xx) |
LU (1) | LU84562A1 (xx) |
NL (1) | NL8204974A (xx) |
PT (1) | PT76037B (xx) |
SE (1) | SE449748B (xx) |
SG (1) | SG29687G (xx) |
ZA (1) | ZA828546B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT387221B (de) * | 1980-09-08 | 1988-12-27 | Bristol Myers Co | Verfahren zur herstellung des neuen |
AT387773B (de) * | 1983-09-12 | 1989-03-10 | Bristol Myers Co | Verfahren zur herstellung von 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)aklyl) iperazin-derivaten |
US4524206A (en) * | 1983-09-12 | 1985-06-18 | Mead Johnson & Company | 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives |
US4619930A (en) * | 1985-01-16 | 1986-10-28 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use |
US4677104A (en) * | 1985-05-06 | 1987-06-30 | Bristol-Myers Company | Antipsychotic fused-ring pyridinylpiperazine derivatives |
CA1278792C (en) * | 1985-05-06 | 1991-01-08 | Joseph P. Yevich | Antipsychotic fused-ring pyridinylpiperazine derivatives |
US4757073A (en) * | 1986-09-30 | 1988-07-12 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylipiperazin-1-yl) pyridines, compositions and use |
US4855430A (en) * | 1987-11-12 | 1989-08-08 | American Home Products Corporation | Polycyclicamine with psychotropic activity |
EP0348460A4 (en) * | 1987-11-12 | 1991-11-27 | American Home Products Corporation | Polycyclicamines with psychotropic activity |
US4880930A (en) * | 1987-11-30 | 1989-11-14 | New James S | Psychotropic acyclic amide derivatives |
US5001130A (en) * | 1988-02-18 | 1991-03-19 | Bristol-Myers Company | Psychotropic heterobicycloalkylpiperazine derivatives |
US5116970A (en) * | 1988-02-18 | 1992-05-26 | New James S | Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones |
US5098904A (en) * | 1990-06-27 | 1992-03-24 | Bristol-Myers Squibb Company | Cerebral function enhancing pyrimidinyl derivatives |
ATE132866T1 (de) * | 1990-10-23 | 1996-01-15 | Akzo Nobel Nv | 4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame |
JPH06504279A (ja) * | 1990-12-24 | 1994-05-19 | メレルダウファーマス−ティカルズ インコーポレイテッド | 欝病及び躁病の治療におけるある種のグルタルイミド誘導体の用途 |
SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
DE69919707T2 (de) | 1998-06-19 | 2005-09-01 | Chiron Corp., Emeryville | Glycogen synthase kinase 3 inhibitoren |
US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
EA017351B1 (ru) * | 2007-03-29 | 2012-11-30 | Общество С Ограниченной Ответственностью "Фармвинг" | Средство противогистаминного антиаллергического действия и способ его получения |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3398151A (en) * | 1966-02-01 | 1968-08-20 | Mead Johnson & Co | Azaspirodecanediones and azaspiroundecanediones |
BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
US3976776A (en) * | 1972-12-06 | 1976-08-24 | Mead Johnson & Company | Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones |
US4182763A (en) * | 1978-05-22 | 1980-01-08 | Mead Johnson & Company | Buspirone anti-anxiety method |
DK251079A (da) * | 1978-06-20 | 1979-12-21 | Synthelabo | Fremgangsmaade til fremstilling af phenylpiperazinderivater |
US4305944A (en) * | 1980-09-08 | 1981-12-15 | Mead Johnson & Company | N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones |
-
1981
- 1981-12-28 US US06/334,689 patent/US4361565A/en not_active Expired - Fee Related
-
1982
- 1982-11-19 ZA ZA828546A patent/ZA828546B/xx unknown
- 1982-11-22 CA CA000416080A patent/CA1237722A/en not_active Expired
- 1982-12-02 AU AU91084/82A patent/AU560667B2/en not_active Ceased
- 1982-12-03 KR KR8205431A patent/KR880002011B1/ko active
- 1982-12-08 GR GR70020A patent/GR77101B/el unknown
- 1982-12-22 IT IT49720/82A patent/IT1158040B/it active
- 1982-12-23 IE IE3068/82A patent/IE54620B1/en not_active IP Right Cessation
- 1982-12-23 CY CY137882A patent/CY1378A/xx unknown
- 1982-12-23 DK DK573282A patent/DK162284C/da active
- 1982-12-23 NL NL8204974A patent/NL8204974A/nl unknown
- 1982-12-23 AT AT0467682A patent/AT380880B/de not_active Expired
- 1982-12-23 ES ES518511A patent/ES8402832A1/es not_active Expired
- 1982-12-23 FI FI824443A patent/FI70892C/fi not_active IP Right Cessation
- 1982-12-23 JP JP57225099A patent/JPS58118583A/ja active Granted
- 1982-12-23 GB GB08236592A patent/GB2114121B/en not_active Expired
- 1982-12-24 FR FR8221751A patent/FR2518994B1/fr not_active Expired
- 1982-12-27 SE SE8207426A patent/SE449748B/sv not_active IP Right Cessation
- 1982-12-27 PT PT76037A patent/PT76037B/pt not_active IP Right Cessation
- 1982-12-27 CH CH7565/82A patent/CH653682A5/de not_active IP Right Cessation
- 1982-12-27 HU HU824172A patent/HU190827B/hu not_active IP Right Cessation
- 1982-12-27 DE DE19823248138 patent/DE3248138A1/de active Granted
- 1982-12-28 BE BE0/209827A patent/BE895505A/fr not_active IP Right Cessation
- 1982-12-29 LU LU84562A patent/LU84562A1/fr unknown
-
1987
- 1987-03-27 SG SG296/87A patent/SG29687G/en unknown
- 1987-03-31 KE KE3714A patent/KE3714A/xx unknown
-
1988
- 1988-01-21 HK HK51/88A patent/HK5188A/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LU84561A1 (fr) | 2-(4-((4,4,-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyrimidines | |
LU84562A1 (fr) | 2-(4-((4,4-dialcoyl-2,6-piperidinedione-1-yl)butyl)-1-piperazinyl)pyridines | |
LU85442A1 (fr) | Agents antidepression a base de 1,2,4-triazol-3-one | |
LU79761A1 (fr) | Procede de preparation de nouveaux composes de phtalazine et de composition pharmaceutique les contenant | |
LU84550A1 (fr) | Derives de piperazine portant un radical de benzisothiazole ou de benzisoxazole | |
LU85796A1 (fr) | Derives antipsychotiques de la 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine | |
JP3160371B2 (ja) | 4−ピリミジンカルボキサミド誘導体、その製造方法および治療への応用 | |
EP0377528B1 (fr) | Pipéridines, procédés de préparation et médicaments les contenant | |
FR2675800A1 (fr) | Derives heterocycliques antiserotonines leur preparation et les medicaments les contenant. | |
FR2567519A1 (fr) | Nouvelles isoindolinyl-alcoyl-piperazines, compositions pharmaceutiques les contenant, et leur procede de preparation | |
WO1998031669A1 (fr) | Nouvelles arylpiperazines derivees de piperidine comme medicaments antidepresseurs | |
EP0084993B1 (fr) | Nouveaux dérivés de benzodioxine, leurs procédés de préparation et les compositions pharmaceutiques les renfermant | |
US4088764A (en) | Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol | |
SU1340585A3 (ru) | Способ получени производных тетразола | |
CN1046158A (zh) | 新硫尿嘧啶衍生物,含这些衍生物的药物组合物及其制备方法 | |
AU644605B2 (en) | Pyridone nitriles useful in treating cardiovascular disease | |
FR2643373A1 (fr) | Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent | |
US5401762A (en) | Aminoalkyl-substituted thiazolin-2-ones, the preparation and use thereof | |
JPS63185948A (ja) | 置換アミノプロピオンアミドおよびその製造方法 | |
CA1025865A (fr) | Procedes de preparation de nouvelles amides heterocycliques | |
JPH01156966A (ja) | リポキシゲナーゼ抑制作用を有するピリダジノン、トリアジノンおよびオキサピリダジノン化合物 | |
JP3492433B2 (ja) | 3−(フェニルアルキルアミノアルキルオキシ)−5−フェニルピラゾール−化合物、その製造のための方法及び中間体、及びこれを含有する心臓循環作用薬剤 | |
FR2543952A1 (fr) | Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique | |
EP1511728B1 (fr) | Derives d oxophenyl-cyclohexyl-propanolamine, leur preparati on et leur application en therapeutique | |
KR900005021B1 (ko) | 1-펜옥시-3-히드록시 인돌릴 알킬아미노-3-프로판올류 및 그 제조방법 |