LT4276B - Eritromicino a 9-o-oksimo dariniai, pasižymintys antibiotiniu aktyvumu - Google Patents

Eritromicino a 9-o-oksimo dariniai, pasižymintys antibiotiniu aktyvumu Download PDF

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Publication number
LT4276B
LT4276B LT97-116A LT97116A LT4276B LT 4276 B LT4276 B LT 4276B LT 97116 A LT97116 A LT 97116A LT 4276 B LT4276 B LT 4276B
Authority
LT
Lithuania
Prior art keywords
erythromycin
ethyl
oxime
formula
hexylamino
Prior art date
Application number
LT97-116A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT97116A (en
Inventor
Franco Pellacini
Giovanna Schioppacassi
Enrico Albini
Daniela Botta
Stefano Romagnano
Francesco Santangelo
Original Assignee
Zambon Group S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group S.P.A. filed Critical Zambon Group S.P.A.
Publication of LT97116A publication Critical patent/LT97116A/xx
Publication of LT4276B publication Critical patent/LT4276B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
LT97-116A 1994-12-13 1997-07-07 Eritromicino a 9-o-oksimo dariniai, pasižymintys antibiotiniu aktyvumu LT4276B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT94MI002496A IT1276901B1 (it) 1994-12-13 1994-12-13 Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica

Publications (2)

Publication Number Publication Date
LT97116A LT97116A (en) 1997-10-27
LT4276B true LT4276B (lt) 1998-01-26

Family

ID=11369979

Family Applications (1)

Application Number Title Priority Date Filing Date
LT97-116A LT4276B (lt) 1994-12-13 1997-07-07 Eritromicino a 9-o-oksimo dariniai, pasižymintys antibiotiniu aktyvumu

Country Status (35)

Country Link
US (1) US5847092A (zh)
EP (1) EP0797579B1 (zh)
JP (1) JPH10510520A (zh)
KR (1) KR100367559B1 (zh)
CN (1) CN1046535C (zh)
AP (1) AP739A (zh)
AT (1) ATE190620T1 (zh)
AU (1) AU690791B2 (zh)
BG (1) BG63261B1 (zh)
BR (1) BR9510015A (zh)
CA (1) CA2207029A1 (zh)
CZ (1) CZ289943B6 (zh)
DE (1) DE69515694T2 (zh)
DK (1) DK0797579T3 (zh)
EE (1) EE03401B1 (zh)
ES (1) ES2144154T3 (zh)
FI (1) FI972493A (zh)
GE (1) GEP20012391B (zh)
GR (1) GR3033622T3 (zh)
HU (1) HU220631B1 (zh)
IT (1) IT1276901B1 (zh)
LT (1) LT4276B (zh)
LV (1) LV11898B (zh)
MD (1) MD1788G2 (zh)
NO (1) NO309816B1 (zh)
NZ (1) NZ297446A (zh)
OA (1) OA10491A (zh)
PL (1) PL182053B1 (zh)
PT (1) PT797579E (zh)
RO (1) RO116282B1 (zh)
RU (1) RU2152951C1 (zh)
SI (1) SI9520124A (zh)
TJ (1) TJ306B (zh)
UA (1) UA48958C2 (zh)
WO (1) WO1996018633A1 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1290447B1 (it) * 1997-03-28 1998-12-03 Zambon Spa Derivati 1,3-ossatiolanici ad attivita' antivirale
IT1301967B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivato di eritromicina ad attivita' antibiotica
IT1301968B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivati di eritromicina ad attivita' antibiotica
IT1306205B1 (it) * 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6947844B2 (en) 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
JP5383037B2 (ja) 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033255A1 (fr) 1980-01-11 1981-08-05 Roussel-Uclaf Nouvelles oximes dérivées de l'érythromycine A, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
EP0216169A2 (en) 1985-08-28 1987-04-01 Beecham Group Plc Erythromycin derivatives
EP0284203A2 (en) 1987-02-24 1988-09-28 Beecham Group Plc Erythromycin derivatives, process for their preparation and their pharmaceutical use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4740502A (en) * 1986-06-20 1988-04-26 Abbott Laboratories Semisynthetic erythromycin antibiotics
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033255A1 (fr) 1980-01-11 1981-08-05 Roussel-Uclaf Nouvelles oximes dérivées de l'érythromycine A, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
EP0216169A2 (en) 1985-08-28 1987-04-01 Beecham Group Plc Erythromycin derivatives
EP0284203A2 (en) 1987-02-24 1988-09-28 Beecham Group Plc Erythromycin derivatives, process for their preparation and their pharmaceutical use

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GASC JC ET AL.: "New ether oxime of erythromycin A a structure activity relationship study", THE JOURNAL OF ANTIBIOTICS, 1991, pages 313 - 330
HERBERT A. KIRST: "Chapter 13. Macrolide Antibiotics", ANNUAL REPORTS IN MEDICINAL CHEMISTRY, 1989, pages 119 - 128
P.A. LARTEY, H. N. NELLANS, S. K. TANAKA: "New Developments in Macrolides: Structures and Antibacterial and Prokinetic Activities", ADVANCES IN PHARMACOLOGY, 1994, pages 307 - 343
RED. T. W. GREENE, P. G. M. WUTS: "Protective Groups in Organic Synthesis (2nd) Second Edition", pages: 309 - 405

Also Published As

Publication number Publication date
HU220631B1 (hu) 2002-03-28
FI972493A0 (fi) 1997-06-12
GEP20012391B (en) 2001-03-25
IT1276901B1 (it) 1997-11-03
MD1788F2 (en) 2001-11-30
MD1788G2 (ro) 2002-05-31
NZ297446A (en) 1999-06-29
AU690791B2 (en) 1998-04-30
EE03401B1 (et) 2001-04-16
FI972493A (fi) 1997-06-12
DE69515694D1 (de) 2000-04-20
ITMI942496A0 (it) 1994-12-13
HUT77126A (hu) 1998-03-02
US5847092A (en) 1998-12-08
EE9700124A (et) 1997-12-15
EP0797579B1 (en) 2000-03-15
PT797579E (pt) 2000-08-31
ES2144154T3 (es) 2000-06-01
TJ306B (en) 2001-08-06
MD970243A (en) 1999-05-31
SI9520124A (sl) 1998-04-30
JPH10510520A (ja) 1998-10-13
CZ289943B6 (cs) 2002-04-17
CN1169727A (zh) 1998-01-07
GR3033622T3 (en) 2000-10-31
RO116282B1 (ro) 2000-12-29
OA10491A (en) 2002-04-10
LV11898A (lv) 1997-12-20
RU2152951C1 (ru) 2000-07-20
KR100367559B1 (ko) 2003-04-21
BR9510015A (pt) 1997-10-28
PL182053B1 (pl) 2001-10-31
BG101570A (en) 1998-02-27
CA2207029A1 (en) 1996-06-20
WO1996018633A1 (en) 1996-06-20
AP9700989A0 (en) 1997-07-31
LT97116A (en) 1997-10-27
CN1046535C (zh) 1999-11-17
PL320688A1 (en) 1997-10-27
ITMI942496A1 (it) 1996-06-13
UA48958C2 (uk) 2002-09-16
LV11898B (en) 1998-03-20
NO972702L (no) 1997-08-13
CZ178697A3 (en) 1997-12-17
DK0797579T3 (da) 2000-06-05
ATE190620T1 (de) 2000-04-15
NO972702D0 (no) 1997-06-12
MX9704253A (es) 1997-09-30
DE69515694T2 (de) 2000-10-26
NO309816B1 (no) 2001-04-02
AU4260396A (en) 1996-07-03
BG63261B1 (bg) 2001-07-31
EP0797579A1 (en) 1997-10-01
AP739A (en) 1999-03-24

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Effective date: 20051207