LT4078B - Therapeutic peptide derivatives - Google Patents
Therapeutic peptide derivatives Download PDFInfo
- Publication number
- LT4078B LT4078B LT96-025A LT96025A LT4078B LT 4078 B LT4078 B LT 4078B LT 96025 A LT96025 A LT 96025A LT 4078 B LT4078 B LT 4078B
- Authority
- LT
- Lithuania
- Prior art keywords
- phe
- cys
- peptide
- thr
- trp
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Obesity (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10419493A | 1993-08-09 | 1993-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
LT96025A LT96025A (en) | 1996-07-25 |
LT4078B true LT4078B (en) | 1996-12-27 |
Family
ID=22299154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LT96-025A LT4078B (en) | 1993-08-09 | 1996-03-06 | Therapeutic peptide derivatives |
Country Status (30)
Country | Link |
---|---|
US (1) | US5552520A (de) |
EP (3) | EP1288224B1 (de) |
JP (3) | JP3618750B2 (de) |
KR (1) | KR100325972B1 (de) |
CN (1) | CN1055700C (de) |
AT (3) | ATE284413T1 (de) |
AU (1) | AU689490B2 (de) |
CA (1) | CA2168113C (de) |
CZ (3) | CZ292586B6 (de) |
DE (3) | DE69434181T2 (de) |
DK (3) | DK1288223T3 (de) |
ES (3) | ES2196031T3 (de) |
FI (1) | FI960584A0 (de) |
GE (1) | GEP20002146B (de) |
HK (2) | HK1053314A1 (de) |
HU (1) | HU224350B1 (de) |
LT (1) | LT4078B (de) |
LV (1) | LV11549B (de) |
MD (1) | MD1591B2 (de) |
NZ (1) | NZ271238A (de) |
PL (1) | PL180612B1 (de) |
PT (2) | PT1288223E (de) |
RO (1) | RO117259B1 (de) |
RU (1) | RU2133252C1 (de) |
SG (1) | SG75092A1 (de) |
SI (2) | SI0788509T1 (de) |
SK (1) | SK15096A3 (de) |
UA (1) | UA44707C2 (de) |
WO (1) | WO1995004752A1 (de) |
ZA (1) | ZA945966B (de) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2774769B2 (ja) * | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
CA2190633A1 (en) * | 1995-03-20 | 1996-09-26 | Kenji Shibata | Novel calcitonin derivatives |
US5824772A (en) * | 1995-04-04 | 1998-10-20 | Advanced Bioconcept, Inc. | Fluorescent somatostatin |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US6479457B2 (en) * | 1995-06-06 | 2002-11-12 | Kinerton Limited | Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides |
US5830431A (en) * | 1995-06-07 | 1998-11-03 | Mallinckrodt Medical, Inc. | Radiolabeled peptide compositions for site-specific targeting |
US7410948B2 (en) | 1995-07-13 | 2008-08-12 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Analogs of parathyroid hormone |
US6544949B1 (en) | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
US5766620A (en) * | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
US7078413B2 (en) | 1996-04-19 | 2006-07-18 | Wisconsin Alumni Research Foundation | Compositions and methods of use for a bombesin peptide |
US6492330B1 (en) * | 1996-08-16 | 2002-12-10 | National Institute Of Immunology | Antiangiogenic drugs |
US5968903A (en) * | 1998-05-07 | 1999-10-19 | Biomeasure, Incorporated | Inhibition of H. pylori proliferation |
US6124263A (en) * | 1998-11-16 | 2000-09-26 | Asta Medica Ag | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists |
US6864234B1 (en) | 1999-06-25 | 2005-03-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Somatostatin agonists |
CZ20014534A3 (cs) * | 1999-06-25 | 2002-06-12 | Societe De Conseils De Recherches Et D´Applic Atio | Peptid, farmaceutický prostředek a způsob |
IES990700A2 (en) | 1999-08-18 | 2001-08-22 | Kinerton Ltd | Process to make a sustained release formulation |
DE60027334T2 (de) * | 1999-08-18 | 2007-03-29 | Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. | Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist |
AU2004200688B2 (en) * | 1999-08-18 | 2007-01-25 | Ipsen Pharma S.A.S. | Sustained release formulation of a peptide |
EP1348444B1 (de) * | 1999-08-18 | 2006-04-12 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist |
US7109166B1 (en) | 1999-08-18 | 2006-09-19 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Sustained release formulation of a peptide |
GB0018891D0 (en) | 2000-08-01 | 2000-09-20 | Novartis Ag | Organic compounds |
US6316414B1 (en) | 2000-07-31 | 2001-11-13 | Dabur Research Foundation | Somatostatin analogs for the treatment of cancer |
MD2074G2 (ro) * | 2000-12-29 | 2003-06-30 | Юрий НИКИТИН | Procedeu şi instalaţie de captare a vaporilor de carburant la staţiile de alimentare cu petrol, condensator al vaporilor de carburant utilizat în instalaţia menţionată |
DE60220157T2 (de) | 2001-03-06 | 2008-01-17 | Il Consorzio Ferrara Richerche | Verfahren zur modulierung der proliferation von medullären schilddrüsen-karzinomzellen |
CA2439498A1 (en) * | 2001-03-08 | 2002-09-19 | The Administrators Of The Tulane Educational Fund | Somatostatin antagonists |
US20030229013A1 (en) * | 2001-12-07 | 2003-12-11 | Shih-Kwang Wu | Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same |
FR2833596B1 (fr) * | 2001-12-14 | 2005-02-18 | Aventis Pharma Sa | Procede de preparation de derives d'echinocandine |
US20040171070A1 (en) * | 2002-05-20 | 2004-09-02 | Ramagauri Bhikhabhai | Peptide analysis using a solid support |
US7186692B2 (en) | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
US7166575B2 (en) | 2002-12-17 | 2007-01-23 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity |
US7229966B2 (en) | 2002-12-17 | 2007-06-12 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity |
EA008829B1 (ru) | 2002-12-17 | 2007-08-31 | Нэстек Фармасьютикал Кампани Инк. | Композиции и способы для усовершенствованной доставки пептидов, связывающихся с y-рецепторами, которую осуществляют через слизистые оболочки, и способы лечения и предотвращения ожирения |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US20090220587A1 (en) * | 2005-02-01 | 2009-09-03 | United State Army | Liposomal drug delivery constructs targeted by lipid-conjugated peptide ligands |
US7741431B2 (en) * | 2005-02-01 | 2010-06-22 | The United States Of America As Represented By The Secretary Of The Army | Liposomes containing novel targeting and/or fusogenic peptides, preparations containing them and therapeutic use thereof |
AU2006297443B2 (en) | 2005-09-29 | 2010-08-12 | Merck Sharp & Dohme Corp. | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
CA2664113C (en) | 2006-09-22 | 2013-05-28 | Merck & Co., Inc. | Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer |
WO2008095063A1 (en) | 2007-01-31 | 2008-08-07 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
EP2508531B1 (de) | 2007-03-28 | 2016-10-19 | President and Fellows of Harvard College | Geheftete Polypeptide |
CA2682727C (en) | 2007-04-02 | 2016-03-22 | Banyu Pharmaceutical Co., Ltd. | Indoledione derivative |
EP2719392B1 (de) | 2008-06-12 | 2019-07-24 | Ipsen Bioinnovation Limited | Fusionproteine zur Verwendung bei der Behandlung von Akromegalie |
JP5799397B2 (ja) | 2008-06-12 | 2015-10-28 | イプセン・バイオイノベーション・リミテッドIpsen Bioinnovation Limited | 癌の抑制 |
GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
US20120172650A1 (en) * | 2009-03-18 | 2012-07-05 | Laurence Katznelson | Use of somatostatin or an analogue thereof in combination with external radiation therapy |
RU2547990C2 (ru) | 2009-09-28 | 2015-04-10 | Интарсия Терапьютикс, Инк. | Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства |
AU2010323117B2 (en) | 2009-11-25 | 2015-09-03 | Capsugel Belgium Nv | Mucosal delivery compositions comprising a peptide complexed with a crown comppound and/or a counter ion |
CN105456206B (zh) | 2010-01-13 | 2018-12-14 | 益普生制药股份有限公司 | 用于延缓释放生长抑素类似物的药物组合物的制备方法 |
CN102260352B (zh) * | 2010-05-28 | 2013-11-20 | 山东先声麦得津生物制药有限公司 | 靶向性白细胞介素融合蛋白及其制备方法与应用 |
EP2399931A1 (de) * | 2010-06-22 | 2011-12-28 | Ipsen Pharma S.A.S. | Neue Oktapeptid-Verbindungen und ihr therapeutischer Einsatz |
SI2603600T1 (sl) | 2010-08-13 | 2019-04-30 | Aileron Therapeutics, Inc. | Peptidomimetični makrocikli |
AU2012326026B2 (en) | 2011-10-18 | 2017-04-13 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
CN112500466B (zh) | 2012-02-15 | 2022-05-03 | 艾瑞朗医疗公司 | 拟肽大环化合物 |
WO2013123267A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
AU2013337388B2 (en) | 2012-11-01 | 2018-08-02 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
KR20170129879A (ko) | 2015-03-20 | 2017-11-27 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
CN108659100A (zh) * | 2017-03-28 | 2018-10-16 | 上海新生源医药集团有限公司 | 具有镇痛作用的多肽及其应用 |
AU2019357621A1 (en) | 2018-10-11 | 2021-05-27 | Intarcia Therapeutics, Inc. | Human amylin analog polypeptides and methods of use |
KR20220017695A (ko) * | 2020-08-05 | 2022-02-14 | 주식회사 레미바이오 | 아스코르브산 유도체 및 이를 포함하는 조성물 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988002756A2 (en) | 1986-10-13 | 1988-04-21 | Sandoz Ag | Peptide derivatives |
US4837303A (en) | 1985-06-25 | 1989-06-06 | Diamalt Aktiengesellschaft | Novel somatostatin derivatives |
US4861755A (en) | 1986-01-16 | 1989-08-29 | Hoechst Aktiengesellschaft | Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use |
WO1989009786A1 (en) | 1988-04-08 | 1989-10-19 | Sandoz Ag | Peptide derivatives |
EP0363589A2 (de) | 1988-08-18 | 1990-04-18 | Syntex (U.S.A.) Inc. | Somatostatin-Analoge |
EP0374089A2 (de) | 1988-11-11 | 1990-06-20 | Sandoz Ag | Verwendung von Somatostatinderivaten als Substanzen zum Schutz der Lunge |
WO1991009837A1 (en) | 1989-12-22 | 1991-07-11 | Commonwealth Scientific And Industrial Research Organisation | Amino acids, peptides or derivatives thereof coupled to fats |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1246055A (en) * | 1980-03-24 | 1988-12-06 | Joseph H. Cort | N-.omega.-substituted hormonogens of vasopressin and its synthetic analogs |
GB9209032D0 (en) * | 1992-04-25 | 1992-06-10 | Ciba Geigy Ag | New peptide derivatives |
-
1994
- 1994-08-08 AT AT02026862T patent/ATE284413T1/de not_active IP Right Cessation
- 1994-08-08 DK DK02026862T patent/DK1288223T3/da active
- 1994-08-08 AT AT94924590T patent/ATE241643T1/de not_active IP Right Cessation
- 1994-08-08 SI SI9430451T patent/SI0788509T1/xx unknown
- 1994-08-08 GE GEAP19943038A patent/GEP20002146B/en unknown
- 1994-08-08 WO PCT/US1994/008875 patent/WO1995004752A1/en active IP Right Grant
- 1994-08-08 RO RO96-00225A patent/RO117259B1/ro unknown
- 1994-08-08 ES ES94924590T patent/ES2196031T3/es not_active Expired - Lifetime
- 1994-08-08 PL PL94312989A patent/PL180612B1/pl not_active IP Right Cessation
- 1994-08-08 PT PT02026862T patent/PT1288223E/pt unknown
- 1994-08-08 CZ CZ1996390A patent/CZ292586B6/cs not_active IP Right Cessation
- 1994-08-08 JP JP50654195A patent/JP3618750B2/ja not_active Expired - Lifetime
- 1994-08-08 ES ES02026863T patent/ES2309131T3/es not_active Expired - Lifetime
- 1994-08-08 UA UA96020456A patent/UA44707C2/uk unknown
- 1994-08-08 SI SI9420051A patent/SI9420051A/sl unknown
- 1994-08-08 SG SG1996005779A patent/SG75092A1/en unknown
- 1994-08-08 EP EP02026863A patent/EP1288224B1/de not_active Expired - Lifetime
- 1994-08-08 SK SK150-96A patent/SK15096A3/sk unknown
- 1994-08-08 EP EP94924590A patent/EP0788509B1/de not_active Expired - Lifetime
- 1994-08-08 AT AT02026863T patent/ATE399177T1/de not_active IP Right Cessation
- 1994-08-08 DE DE69434181T patent/DE69434181T2/de not_active Expired - Lifetime
- 1994-08-08 HU HU9600281A patent/HU224350B1/hu not_active IP Right Cessation
- 1994-08-08 DE DE69435105T patent/DE69435105D1/de not_active Expired - Lifetime
- 1994-08-08 DK DK02026863T patent/DK1288224T3/da active
- 1994-08-08 AU AU74819/94A patent/AU689490B2/en not_active Ceased
- 1994-08-08 DE DE69432758T patent/DE69432758T2/de not_active Expired - Lifetime
- 1994-08-08 KR KR1019960700664A patent/KR100325972B1/ko not_active IP Right Cessation
- 1994-08-08 RU RU96104340A patent/RU2133252C1/ru not_active IP Right Cessation
- 1994-08-08 CN CN94193717A patent/CN1055700C/zh not_active Expired - Fee Related
- 1994-08-08 NZ NZ271238A patent/NZ271238A/en not_active IP Right Cessation
- 1994-08-08 CA CA002168113A patent/CA2168113C/en not_active Expired - Fee Related
- 1994-08-08 ES ES02026862T patent/ES2229045T3/es not_active Expired - Lifetime
- 1994-08-08 EP EP02026862A patent/EP1288223B1/de not_active Expired - Lifetime
- 1994-08-08 DK DK94924590T patent/DK0788509T3/da active
- 1994-08-08 PT PT94924590T patent/PT788509E/pt unknown
- 1994-08-08 MD MD96-0137A patent/MD1591B2/ro unknown
- 1994-08-09 US US08/287,957 patent/US5552520A/en not_active Expired - Lifetime
- 1994-08-09 ZA ZA945966A patent/ZA945966B/xx unknown
-
1996
- 1996-02-08 FI FI960584A patent/FI960584A0/fi not_active Application Discontinuation
- 1996-03-06 LT LT96-025A patent/LT4078B/lt not_active IP Right Cessation
- 1996-03-08 LV LVP-96-71A patent/LV11549B/en unknown
-
2000
- 2000-03-22 CZ CZ20001033A patent/CZ289552B6/cs not_active IP Right Cessation
- 2000-03-22 CZ CZ20001032A patent/CZ289590B6/cs not_active IP Right Cessation
-
2003
- 2003-08-04 HK HK03105592A patent/HK1053314A1/xx not_active IP Right Cessation
- 2003-08-04 HK HK03105591A patent/HK1053313A1/xx not_active IP Right Cessation
-
2004
- 2004-08-12 JP JP2004235535A patent/JP3785179B2/ja not_active Expired - Lifetime
- 2004-08-12 JP JP2004235503A patent/JP3869439B2/ja not_active Expired - Lifetime
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4837303A (en) | 1985-06-25 | 1989-06-06 | Diamalt Aktiengesellschaft | Novel somatostatin derivatives |
US4861755A (en) | 1986-01-16 | 1989-08-29 | Hoechst Aktiengesellschaft | Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use |
WO1988002756A2 (en) | 1986-10-13 | 1988-04-21 | Sandoz Ag | Peptide derivatives |
WO1989009786A1 (en) | 1988-04-08 | 1989-10-19 | Sandoz Ag | Peptide derivatives |
EP0363589A2 (de) | 1988-08-18 | 1990-04-18 | Syntex (U.S.A.) Inc. | Somatostatin-Analoge |
EP0374089A2 (de) | 1988-11-11 | 1990-06-20 | Sandoz Ag | Verwendung von Somatostatinderivaten als Substanzen zum Schutz der Lunge |
WO1991009837A1 (en) | 1989-12-22 | 1991-07-11 | Commonwealth Scientific And Industrial Research Organisation | Amino acids, peptides or derivatives thereof coupled to fats |
Non-Patent Citations (2)
Title |
---|
PAUL A. SEIB ET AL.: "Synthesis and stability of L-ascorbate 2-sulphate", J. CHEM. SOC., PERKIN TRANS. 1,, 1974, pages 1220 - 1224 |
WANG LH ET AL.: "des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor antagonists, partial agonists, or agonists.", J. BIOL. CHEM., 1990, pages 15695 - 703, XP000151168 |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LT4078B (en) | Therapeutic peptide derivatives | |
CA3084004C (en) | Incretin analogs and uses thereof | |
US20140162943A1 (en) | N-terminus conformationally constrained glp-1 receptor agonist compounds | |
SK211290A3 (en) | Octapeptide and therapeutical agent containing the same | |
JP2023078367A (ja) | 新規glp-1類似体 | |
EP0438566B1 (de) | Substance P Antagoniste | |
AU2020408139B2 (en) | Incretin analogs and uses thereof | |
JP3514754B2 (ja) | 肝臓癌の治療 | |
HUT62604A (en) | Process for producing peptides for treating tissue proliferation and pharmaceutical compositions comprising same | |
MXPA00000455A (en) | Therapeutic peptide derivatives | |
DE4431121A1 (de) | Herstellung von konformationsstabilisierten Calcitonin-Analoga mit erhöhter hypocalcämischer Wirkung in vivo |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM9A | Lapsed patents |
Effective date: 19970808 |