LT3986890T - Benzizoksazolo sulfonamido dariniai - Google Patents

Benzizoksazolo sulfonamido dariniai

Info

Publication number
LT3986890T
LT3986890T LTEPPCT/IB2020/055589T LTIB2020055589T LT3986890T LT 3986890 T LT3986890 T LT 3986890T LT IB2020055589 T LTIB2020055589 T LT IB2020055589T LT 3986890 T LT3986890 T LT 3986890T
Authority
LT
Lithuania
Prior art keywords
sulfonamide derivatives
benzisoxazole
benzisoxazole sulfonamide
derivatives
sulfonamide
Prior art date
Application number
LTEPPCT/IB2020/055589T
Other languages
English (en)
Lithuanian (lt)
Inventor
Ylva Elisabet Bergman BOZIKIS
Oleg Brodsky
Michelle Ang CAMERINO
Samantha Elizabeth GREASLEY
Robert Louis Hoffman
Robert Arnold Kumpf
Pei-Pei Kung
Paul Francis Richardson
Paul Anthony Stupple
Scott Channing Sutton
Original Assignee
Pfizer Inc.
Ctxt Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc., Ctxt Pty Ltd filed Critical Pfizer Inc.
Publication of LT3986890T publication Critical patent/LT3986890T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
LTEPPCT/IB2020/055589T 2019-06-18 2020-06-16 Benzizoksazolo sulfonamido dariniai LT3986890T (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962863199P 2019-06-18 2019-06-18
US201962953223P 2019-12-24 2019-12-24
US202063025278P 2020-05-15 2020-05-15
PCT/IB2020/055589 WO2020254946A1 (en) 2019-06-18 2020-06-16 Benzisoxazole sulfonamide derivatives

Publications (1)

Publication Number Publication Date
LT3986890T true LT3986890T (lt) 2023-12-11

Family

ID=71738189

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/IB2020/055589T LT3986890T (lt) 2019-06-18 2020-06-16 Benzizoksazolo sulfonamido dariniai

Country Status (29)

Country Link
US (2) US11492346B2 (zh)
EP (2) EP3986890B1 (zh)
JP (2) JP7352662B2 (zh)
KR (1) KR20220024671A (zh)
CN (1) CN114364672A (zh)
AU (2) AU2020296361A1 (zh)
BR (1) BR112021025528A2 (zh)
CA (1) CA3143666C (zh)
CL (1) CL2021003372A1 (zh)
CO (1) CO2021017504A2 (zh)
CR (1) CR20210627A (zh)
DK (1) DK3986890T3 (zh)
EC (1) ECSP21091615A (zh)
ES (1) ES2969616T3 (zh)
FI (1) FI3986890T3 (zh)
HR (1) HRP20231501T1 (zh)
HU (1) HUE064683T2 (zh)
IL (1) IL288802A (zh)
LT (1) LT3986890T (zh)
MD (1) MD3986890T2 (zh)
MX (1) MX2021016085A (zh)
PE (1) PE20220808A1 (zh)
PL (1) PL3986890T3 (zh)
PT (1) PT3986890T (zh)
RS (1) RS64931B1 (zh)
SI (1) SI3986890T1 (zh)
TW (1) TWI787620B (zh)
UY (1) UY38752A (zh)
WO (1) WO2020254946A1 (zh)

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GB201810092D0 (en) * 2018-06-20 2018-08-08 Ctxt Pty Ltd Compounds
MX2021014441A (es) 2019-05-31 2022-01-06 Ikena Oncology Inc Inhibidores del dominio asociado mejorador de la transcripcion (tead) y usos de los mismos.
EP3986890B1 (en) * 2019-06-18 2023-11-15 Pfizer Inc. Benzisoxazole sulfonamide derivatives
AU2021308406A1 (en) * 2020-07-15 2023-02-23 Ctxt Pty Ltd KAT6 inhibitor methods and combinations for cancer treatment
WO2022187688A1 (en) * 2021-03-05 2022-09-09 Umbra Therapeutics Inc. Covalent kras-binding compounds for therapeutic purposes
WO2022187693A1 (en) * 2021-03-05 2022-09-09 Umbra Therapeutics Inc. Covalent cdk2-binding compounds for therapeutic purposes
CA3221048A1 (en) * 2021-05-21 2022-11-24 Aurigene Oncology Limited Fused isoxazolyl compounds as kat6a inhibitors
CN118382622A (zh) 2021-07-05 2024-07-23 杭州英创医药科技有限公司 作为kat6抑制剂的化合物
TW202321263A (zh) 2021-08-10 2023-06-01 大陸商江蘇恆瑞醫藥股份有限公司 磺醯胺衍生物、其製備方法及其在醫藥上的應用
TW202334163A (zh) * 2021-11-16 2023-09-01 香港商英矽智能科技知識產權有限公司 離胺酸乙醯基轉移酶6a (kat6a)抑制劑及其用途
CA3241874A1 (en) * 2021-12-13 2023-06-22 Aurigene Oncology Limited Fused benzoisoxazolyl compounds as kat6a inhibitors
WO2023192817A1 (en) 2022-03-28 2023-10-05 Isosterix, Inc. Inhibitors of the myst family of lysine acetyl transferases
WO2023245150A1 (en) * 2022-06-16 2023-12-21 Prelude Therapeutics Incorporated Kat6 targeting compounds with ubiquitin ligase binding moiety
WO2024023703A1 (en) 2022-07-29 2024-02-01 Pfizer Inc. Dosing regimens comprising a kat6 inhibitor for the treatment of cancer
WO2024131772A1 (zh) * 2022-12-20 2024-06-27 杭州中美华东制药有限公司 具有sting抑制作用的含肟化合物及其药物组合物和用途
WO2024165035A1 (zh) * 2023-02-10 2024-08-15 江苏恒瑞医药股份有限公司 一种磺酰胺衍生物结晶形式及其制备方法

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Also Published As

Publication number Publication date
US20230174522A1 (en) 2023-06-08
US11492346B2 (en) 2022-11-08
WO2020254946A1 (en) 2020-12-24
IL288802A (en) 2022-02-01
MX2021016085A (es) 2022-04-20
EP3986890A1 (en) 2022-04-27
JP7352662B2 (ja) 2023-09-28
JP2023175821A (ja) 2023-12-12
AU2023274178A1 (en) 2024-02-15
CA3143666C (en) 2024-06-11
BR112021025528A2 (pt) 2022-04-19
CA3143666A1 (en) 2020-12-24
ECSP21091615A (es) 2022-01-31
CN114364672A (zh) 2022-04-15
JP2022537285A (ja) 2022-08-25
EP3986890B1 (en) 2023-11-15
TW202115048A (zh) 2021-04-16
CR20210627A (es) 2022-02-08
CL2021003372A1 (es) 2022-10-07
FI3986890T3 (fi) 2024-01-15
CO2021017504A2 (es) 2022-01-17
SI3986890T1 (sl) 2024-03-29
HUE064683T2 (hu) 2024-04-28
EP4299135A3 (en) 2024-02-28
AU2020296361A1 (en) 2022-01-06
RS64931B1 (sr) 2023-12-29
DK3986890T3 (da) 2023-12-18
PT3986890T (pt) 2024-01-17
HRP20231501T1 (hr) 2024-03-01
PE20220808A1 (es) 2022-05-20
MD3986890T2 (ro) 2024-04-30
US20200399258A1 (en) 2020-12-24
KR20220024671A (ko) 2022-03-03
ES2969616T3 (es) 2024-05-21
UY38752A (es) 2021-01-29
PL3986890T3 (pl) 2024-03-11
EP4299135A2 (en) 2024-01-03
TWI787620B (zh) 2022-12-21

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