KR960703002A - 주입액으로 충전시킨 용기, 주입제제, 및 바이타민을 포함하는 고칼고리 주입제제(Transfusion container, transfusion preparation, and comprehensive vitamin-containing high-calorie transfusion preparation) - Google Patents

주입액으로 충전시킨 용기, 주입제제, 및 바이타민을 포함하는 고칼고리 주입제제(Transfusion container, transfusion preparation, and comprehensive vitamin-containing high-calorie transfusion preparation) Download PDF

Info

Publication number
KR960703002A
KR960703002A KR1019950705786A KR19950705786A KR960703002A KR 960703002 A KR960703002 A KR 960703002A KR 1019950705786 A KR1019950705786 A KR 1019950705786A KR 19950705786 A KR19950705786 A KR 19950705786A KR 960703002 A KR960703002 A KR 960703002A
Authority
KR
South Korea
Prior art keywords
vitamin
meq
infusion
infusions
injection liquid
Prior art date
Application number
KR1019950705786A
Other languages
English (en)
Other versions
KR100426153B1 (ko
Inventor
다카에 기도
히데토 고다이라
고지 무네치카
슌이치 아베
시게오 이이
가즈마사 요코야마
Original Assignee
가와노 다케히코
가부시키가이샤 미도리쥬지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14425035&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR960703002(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 가와노 다케히코, 가부시키가이샤 미도리쥬지 filed Critical 가와노 다케히코
Publication of KR960703002A publication Critical patent/KR960703002A/ko
Application granted granted Critical
Publication of KR100426153B1 publication Critical patent/KR100426153B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2034—Separating means having separation clips

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 당, 아미노산, 전해질, 지방 유액 및 바이타민을 함유하는주입제제를 제조하는데 유용한 주입액으로 충전시킨 용기에 관한 것이다. 용기는 격리 수단에 의해 서로 격리되어 있는 2개의 구획을 지니고 있으며, 지방 유액, 당 및 특정의 바이타민을 포함하는 주입액을 함유하는 제1구획과 아미노산, 전해질 및 기타 특정의 바이타민을 포함하는 주입액을 함유하는 제2구획을 갖는다. 당, 아미노산, 전해질, 지방 유액 및 바이타민을 함유하는 주입 제제는, 사용하기 전에 단순히 격리 수단을 제거한 다음, 2개의 구획내에 함유된 주입액을 함께 혼합함으로써 용이하고 무균적으로 제조될 수 있다.

Description

주입액으로 충전시킨 용기, 주입제제, 및 바이타민을 포함하는 고칼고리 주입제제(Transfusion container transfusion preparation, and comprehensive vitamin-containing high-calorie transfusion preparation)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 서로가 격리 수단에 의해 격리되어 있는 두개의 구획을 가지며 제1구획내에 지방 유액, 당, 바이타민 B1, 바이타민 B2, 바이타민 B12, 바이타민 A, 바이타민 D, 바이타민 E 및 바이타민 K를 포함하는 주입액과 제2구획내에 아미노산, 전해질, 바이타민 C 및 폴산을 포함하는 주입액을 함유함을 특징으로 하는, 주입액으로 충전시킨 용기.
  2. 제1항에 있어서, 제1구획내의 주입액이 0.1 내지 30(w/v)%의 지방, 0.01 내지 10(w/v)%의 유화제, 5 내지 60(w/v)%의 당, 1 내지 30mg/ℓ의 바이타민 B1, 1 내지 20mg/ℓ의 바이타민 B2, 1 내지 50㎍/ℓ의 바이타민 B12, 1000 내지 8000IU/ℓ의 바이타민 A, 100 내지 1500IU/ℓ의 바이타민 D, 5 내지 60mg/ℓ의 바이타민 E 및 0.2 내지 10mg/ℓ의 바이타민 K를 함유하는 주입액으로 충전시킨 용기.
  3. 제1항 또는 제2항에 있어서, 제2구획내에 주입액이 전체적으로 1 내지 15(w/v)%의 아미노산; 전해질로서, 50 내지 180mEq/ℓ의 Na, 40 내지 135mEq/ℓ의 K, 10 내지 50mEq/ℓ의 Ca, 5 내지 30mEq/ℓ의 Mg, 0 내지 225mEq/ℓ의 Cl, 3 내지 40mEq/ℓ의 P 및 0 내지 100μmol/ℓ의 Zn; 50 내지 500mg/ℓ의 바이타민 C 및 0.1 내지 2mg/ℓ의 폴산을 함유하는 주입액으로 충전시킨 용기.
  4. 제1항 내지 제3항중 어느 한 항에 있어서, 제1구획과 제2구획중 하나 이상이 바이타민 B6, 판토텐산, 니코틴산 및 바이오틴을 함유하는 주입액으로 충전시킨 용기.
  5. 지방 유액, 당, 바이타민 B1, 바이타민 B2, 바이타민 B12, 바이타민 A, 바이타민 D, 바이타민 E 및 바이타민 K를 포함하는 주입제제.
  6. 제5항에 있어서, 주입액이 0.1 내지 30(w/v)%의 지방, 0.01 내지 10(w/v)%의 유화제, 5내지 60(w/v)%의 당, 1 내지 30mg/ℓ의 바이타민 B1, 1 내지 20mg/ℓ의 바이타민 B2, 1 내지 50㎍/ℓ의 바이타민 B12, 1000 내지 8000IU/ℓ의 바이타민 A, 100 내지 1500IU/ℓ의 바이타민 D, 5 내지 60mg/ℓ의 바이타민 E 및 0.2 내지 10mg/ℓ의 바이타민 K를 함유하는 주입제제.
  7. 아미노산, 전해질, 바이타민 C 및 폴산을 포함하는 주입제제.
  8. 제7항에 있어서, 주입액이 전체적으로 1 내지 15(w/v)%의 아미노산; 전해질로서; 50 내지 180mEq/ℓ의 Na, 40 내지 135msq/ℓ의 K, 10 내지 50mEq/ℓ의 Ca, 5 내지 30mEq/ℓ의 Mg, 0 내지 225mEq/ℓ의 Cl, 3 내지 40mEq/ℓ의 P 및 0 내지 100μmol/ℓ의 Zn; 50 내지 500mg/ℓ의 바이타민 C 및 0.1 내지 2mg/ℓ의 폴산을 함유하는 주입제제.
  9. 제1항 내지 제4항중 어느 한 항에 따른 주입액을 충전시킨 용기내의 격리 수단을 제거하여 제1구획과 제2구획내에 포함된 주입액을 혼합시켜 제조한, 지방 유액, 당, 아미노산, 전해질 및 바이타민을 포함하는 고칼로리 주입 제제.
  10. 제9항에 있어서, 다음의 성분들을 함유하는 고칼고리 주입제제 :
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950705786A 1994-04-20 1995-04-20 주입액으로충전시킨용기,주입제제및바이타민을포함하는고칼로리주입제제 KR100426153B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP94-106097 1994-04-20
JP10609794 1994-04-20
JP94-106,097 1994-04-20

Publications (2)

Publication Number Publication Date
KR960703002A true KR960703002A (ko) 1996-06-19
KR100426153B1 KR100426153B1 (ko) 2004-06-16

Family

ID=14425035

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950705786A KR100426153B1 (ko) 1994-04-20 1995-04-20 주입액으로충전시킨용기,주입제제및바이타민을포함하는고칼로리주입제제

Country Status (9)

Country Link
US (1) US5728681A (ko)
EP (1) EP0704199B1 (ko)
KR (1) KR100426153B1 (ko)
CN (1) CN1128946A (ko)
CA (1) CA2165209A1 (ko)
DE (1) DE69529952T2 (ko)
DK (1) DK0704199T3 (ko)
ES (1) ES2189827T3 (ko)
WO (1) WO1995028906A1 (ko)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19503190A1 (de) * 1995-02-01 1996-08-08 Dietl Hans Mittel zur Beeinflussung von Störungen der Knochenbildung
JPH0987177A (ja) * 1995-09-20 1997-03-31 Green Cross Corp:The 安定なビタミンｃ製剤
ZA978002B (en) 1996-09-11 1998-03-02 Baxter Int Containers and methods for storing and admixing medical solutions.
DE19911777A1 (de) * 1999-03-17 2000-09-21 Merck Patent Gmbh Verfahren zur Herstellung von kosmetischen Formulierungen
US8105258B2 (en) * 1999-04-26 2012-01-31 Baxter International Inc. Citrate anticoagulation system for extracorporeal blood treatments
US7186420B2 (en) * 1999-04-26 2007-03-06 Edwards Lifesciences Corporation Multi-part substitution infusion fluids and matching anticoagulants
US7678097B1 (en) 1999-11-12 2010-03-16 Baxter International Inc. Containers and methods for manufacturing same
US20050194060A1 (en) * 2004-03-03 2005-09-08 Vincent Houwaert Peelable seal closure assembly
WO2001070591A1 (en) 2000-03-21 2001-09-27 Suzanne Jaffe Stillman Infusion packet with useful and decorative elements, support member, delivery system and method
US8642051B2 (en) * 2000-03-21 2014-02-04 Suzanne Jaffe Stillman Method of hydration; infusion packet system(s), support member(s), delivery system(s), and method(s); with business model(s) and Method(s)
EP1275369A1 (en) * 2001-07-10 2003-01-15 Goldschmidt AG Folic acid containing personal care product
US7175614B2 (en) * 2002-10-17 2007-02-13 Baxter International Inc. Peelable seal
TWI319984B (en) * 2003-06-06 2010-02-01 Sterile combined preparation
KR101231965B1 (ko) * 2005-04-28 2013-02-08 가부시키가이샤 오츠까 세이야꾸 고죠 약액 용기 수용체 및 그 제조 방법
US9004761B2 (en) 2006-05-01 2015-04-14 Baxter International Inc. Multiple chamber container with mistake proof administration system
PT2080501E (pt) * 2006-10-27 2015-07-31 Otsuka Pharma Co Ltd Solução de fármaco tendo um teor reduzido de oxigénio dissolvido, método de produção da mesma e unidade para conter a solução de fármaco tendo um teor reduzido de oxigénio dissolvido
DE102007028733A1 (de) * 2007-06-21 2008-12-24 Fresenius Kabi Deutschland Gmbh Behältnis zur Verwendung in der enteralen Ernährung
US9139456B2 (en) 2008-04-16 2015-09-22 The Curators Of The University Of Missouri Chelating compounds and immobilized tethered chelators
US9259670B2 (en) 2008-04-16 2016-02-16 The University Of Kentucky Research Foundation Flow-through filter to remove aluminum from medical solutions
US7932326B2 (en) * 2008-04-16 2011-04-26 The University Of Kentucky Research Foundation Chelating compounds and immobilized tethered chelators
WO2010011927A1 (en) 2008-07-25 2010-01-28 Noventis, Inc. Compositions and methods for the prevention and treatment of cardiovascular diseases
MX2010000660A (es) * 2009-12-11 2011-06-14 Abbott Lab Soluciones de rehidratacion oral que comprenden dextrosa.
CN106924181A (zh) * 2010-05-07 2017-07-07 Ea制药株式会社 混合有维生素的外周静脉给药用营养输液
CA2806208C (en) * 2010-07-22 2018-02-13 Zishan Haroon Methods of treating or ameliorating diseases and enhancing performance comprising the use of a magnetic dipole stabilized solution
AU2015268572B2 (en) * 2010-11-29 2017-09-07 Otsuka Pharmaceutical Factory, Inc. Infusion preparation
EP2647370B1 (en) 2010-11-29 2019-02-27 Otsuka Pharmaceutical Factory, Inc. Infusion preparation
CN102526032B (zh) * 2011-12-27 2013-02-13 贵州扬生医用器材有限公司 含复方氨基酸的脂质体制剂配方及其制备方法
US9392814B2 (en) 2014-06-06 2016-07-19 Nicholas J. Singer Delivery system for drinks
NO20150142A1 (en) * 2015-01-30 2016-08-01 Pronova Biopharma Norge As Enteral feeding device
WO2016128235A1 (en) * 2015-02-11 2016-08-18 Nestec S.A. Vitamin a composition
USD773313S1 (en) 2015-06-23 2016-12-06 Nicholas J. Singer Package
CN111526730B (zh) 2017-12-29 2024-02-23 卡夫食品集团品牌有限责任公司 使用天然稳定剂改善的水包油乳液的氧化稳定性
JP7370343B2 (ja) 2018-05-18 2023-10-27 バクスター・インターナショナル・インコーポレイテッド 二重チャンバ可撓性容器、作製方法、およびそれを使用する薬物製品
EP3973950A1 (en) * 2020-09-25 2022-03-30 Baxter International Inc Parenteral nutrition formulation comprising vitamin b12

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB162005A (en) * 1919-10-16 1921-04-18 Gerard John Phillips Improvements relating to the method of stowing, transporting and lowering ships boats
GB1464797A (en) * 1973-08-02 1977-02-16 American Cyanamid Co Injectable liquid vitamin preparation
DE2433173C3 (de) * 1974-07-10 1980-02-07 J. Pfrimmer & Co, 8520 Erlangen Verwendung von Cholansaurederivaten
JPS5677222A (en) * 1979-07-02 1981-06-25 Hiroe Kishi Vitamin preparation
JPS58162515A (ja) * 1982-03-19 1983-09-27 Tanabe Seiyaku Co Ltd 末梢静脈注入用加電解質アミノ酸輸液
JPS58162517A (ja) * 1982-03-19 1983-09-27 Green Cross Corp:The 脂溶性ビタミン含有脂肪乳剤
JPH0748991B2 (ja) * 1984-08-29 1995-05-31 日本油脂株式会社 経管栄養組成物
JPH0680008B2 (ja) * 1985-12-09 1994-10-12 森夫 葛西 癌用アミノ酸輸液
JP3049280B2 (ja) * 1990-10-05 2000-06-05 味の素ファルマ株式会社 栄養輸液入りバッグ
JP3364932B2 (ja) * 1991-07-26 2003-01-08 三菱ウェルファーマ株式会社 輸液入り容器
ES2188704T3 (es) * 1991-04-26 2003-07-01 Mitsubishi Pharma Corp Recipiente relleno con liquidos de infusion.
DE69328794T2 (de) * 1992-10-22 2000-11-09 Yoshitomi Pharmaceutical Behälter mit transfusionsflüssigkeit und verbereitete transfusionsflüssigkeit

Also Published As

Publication number Publication date
DE69529952T2 (de) 2003-12-11
ES2189827T3 (es) 2003-07-16
WO1995028906A1 (fr) 1995-11-02
EP0704199A1 (en) 1996-04-03
DK0704199T3 (da) 2003-04-28
KR100426153B1 (ko) 2004-06-16
EP0704199A4 (en) 1998-04-22
US5728681A (en) 1998-03-17
CN1128946A (zh) 1996-08-14
EP0704199B1 (en) 2003-03-19
CA2165209A1 (en) 1995-11-02
DE69529952D1 (de) 2003-04-24

Similar Documents

Publication Publication Date Title
KR960703002A (ko) 주입액으로 충전시킨 용기, 주입제제, 및 바이타민을 포함하는 고칼고리 주입제제(Transfusion container, transfusion preparation, and comprehensive vitamin-containing high-calorie transfusion preparation)
AU777410B2 (en) Preserved pharmaceutical formulations
Vanrenterghem et al. DOUBLE-BLIND COMPARISON OF TWO CORTICOSTEROID REGIMENS PLUS MYCOPHENOLATE MOFETIL AND CYCLOSPORINE FOR PREVENTION OF ACUTE RENAL ALLOGRAFT REJECTION1
KR950703922A (ko) 주입액으로 충전시킨 용기 및 주입제제 (Transfusion liquid-containing holder and prepared transfusion liquid)
Smith et al. Effects of oral contraceptive steroids on vitamin and lipid levels in serum
DE60019239D1 (de) Fettlösliche Vitamine enthaltende Zusammensetzungen
Srikantia et al. Effect of a single massive dose of vitamin A on serum and liver levels of the vitamin
EP0191489B1 (en) Stabilized active forms of vitamin d3
Kirkemo et al. Serum vitamin level maintenance in cancer patients on total parenteral nutrition
Horrobin et al. Water-losing action of antidiuretic hormone in the presence of excess cortisol: restoration of normal action by prolactin or by oxytocin
JP2939082B2 (ja) 安定なビタミンａパルミテート及びビタミンｅ類可溶化点眼剤
Chan Adaptation of urinary nitrogen excretion in infants to changes in protein intake
EP0199992A1 (en) Adsorption-resistant peptide composition and use of benzalkonium or benzethonium chloride in the preparation thereof
JPS58162517A (ja) 脂溶性ビタミン含有脂肪乳剤
Hardy et al. The stability and comparative clearance of TPN mixtures with lipid
Jones et al. Pernicious anemia and related anemias treated with vitamin B12
JPH01143826A (ja) 微粒子脂肪乳剤
JPH0133087B2 (ko)
Butler et al. Leucocyte and thymus changes in the pyridoxine-deficient young and adult male rat.
JPS631923B2 (ko)
Borch-Iohnsen et al. The effect of daily low-dose iron supplements in female blood donors with depleted iron stores: comparison with female non-donors
JP3155312B2 (ja) 安定な静脈注射用総合ビタミン剤
JP2614956B2 (ja) ビタミン凍結乾燥製剤
JPH062664B2 (ja) 安定な総合ビタミン凍結乾燥製剤
GB2105589A (en) Injectable suspensions containing maleic acid or a salt thereof as a stabilising agent

Legal Events

Date Code Title Description
N231 Notification of change of applicant
A201 Request for examination
E902 Notification of reason for refusal
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee