KR940002224A - 2-클로로-5-아미노메틸-피리딘의 제조방법 - Google Patents

2-클로로-5-아미노메틸-피리딘의 제조방법 Download PDF

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Publication number
KR940002224A
KR940002224A KR1019930012396A KR930012396A KR940002224A KR 940002224 A KR940002224 A KR 940002224A KR 1019930012396 A KR1019930012396 A KR 1019930012396A KR 930012396 A KR930012396 A KR 930012396A KR 940002224 A KR940002224 A KR 940002224A
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KR
South Korea
Prior art keywords
chloro
pyridine
aminomethyl
preparing
formula
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KR1019930012396A
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English (en)
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KR100282477B1 (ko
Inventor
디이르 한스-요하임
Original Assignee
만프레드 조벨
바이엘 악티엔게젤샤프트
클라우스 로이터
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Publication of KR940002224A publication Critical patent/KR940002224A/ko
Application granted granted Critical
Publication of KR100282477B1 publication Critical patent/KR100282477B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)

Abstract

본 발명은 구조식(Ⅱ)의 2-클로로-5-시아노-피리딘을 암모니아의 존재하 및 무수 금속 촉매의 존재하에 수소와 반응시킴으로써 구조식(Ⅰ)의 2-클로로-5-아미노메틸-피리딘을 제조하는 방법에 있어서, 반응을 20℃ 내지 150℃ 사이의 온도에서 비극성 비양자성 희석제 중에서 수행함을 특징으로 하는 방법에 관한 것이다.

Description

2-클로로-5-아미노메틸-피리딘의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 구조식(Ⅱ)의 2-클로로-5-시아노-피리딘을 암모니아의 존재하 및 무수 금속 촉매의 존재하에 수소와 반응시킴으로써 구조식(Ⅰ)의 2-클로로-5-아미노메틸-피리딘을 제조하는 방법에 있어서, 반응을 20℃ 내지 150℃ 사이의 온도에서 비극성 비양자성 희석제 중에서 수행함을 특징으로 하는 방법.
  2. 제1항에 있어서, 희석제로서 지방족 또는 방향족 탄화수소를 사용함을 특징으로 하는 방법.
  3. 제1항에 있어서, 희석제로서 톨루엔 또는 크실렌을 사용함을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930012396A 1992-07-06 1993-07-02 2-클로로-5-아미노메틸-피리딘의 제조방법 KR100282477B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4222152.8 1992-07-06
DE4222152A DE4222152A1 (de) 1992-07-06 1992-07-06 Verfahren zur Herstellung von 2-Chlor-5-aminomethyl-pyridin

Publications (2)

Publication Number Publication Date
KR940002224A true KR940002224A (ko) 1994-02-16
KR100282477B1 KR100282477B1 (ko) 2001-02-15

Family

ID=6462584

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930012396A KR100282477B1 (ko) 1992-07-06 1993-07-02 2-클로로-5-아미노메틸-피리딘의 제조방법

Country Status (12)

Country Link
US (1) US5453506A (ko)
EP (1) EP0579970B1 (ko)
JP (1) JP3205648B2 (ko)
KR (1) KR100282477B1 (ko)
CN (1) CN1036585C (ko)
AT (1) ATE190306T1 (ko)
DE (2) DE4222152A1 (ko)
ES (1) ES2142838T3 (ko)
HU (1) HU213624B (ko)
IL (1) IL106192A (ko)
MX (1) MX9303805A (ko)
TW (1) TW321637B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3031727B2 (ja) * 1991-02-04 2000-04-10 広栄化学工業株式会社 α位に塩素原子を有するアミノメチルピリジン類の製造方法
DE4423353A1 (de) 1994-07-04 1996-01-11 Bayer Ag Verfahren zur Herstellung N-acylierter 2-Chlor-5-aminomethylpyridine
WO1997009312A1 (fr) * 1995-09-08 1997-03-13 Nippon Soda Co., Ltd. Processus de production de 3-(aminomethyl)-6-chloropyridines
US6239280B1 (en) 1999-06-30 2001-05-29 Merck & Co., Inc. Process for synthesizing biaryl inhibitors of farnesyl-protein transferase
DE60125378T2 (de) 2000-08-25 2007-04-26 Bayer Cropscience S.A. Verfahren zur Herstellung von 2-AMINOMETHYL-HALOGEN-PYRIDINEN
US6873915B2 (en) * 2001-08-24 2005-03-29 Surromed, Inc. Peak selection in multidimensional data
ES2912531T3 (es) * 2016-12-21 2022-05-26 Bayer Cropscience Ag Hidrogenación de un derivado de 2-metil cianopiridilo sustituido en presencia de un catalizador de cobalto Raney

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5542989B2 (ko) * 1972-06-30 1980-11-04
JPS5422354A (en) * 1977-07-21 1979-02-20 Sagami Chem Res Center 2-chloro-2-cyano-7-aklylbicyclo-(2.2.1)heptane and its preparation
US4499097A (en) * 1983-03-10 1985-02-12 American Cyanamid Company 2-(Pyridyl)imidazolyl ketones
JPH06749B2 (ja) * 1985-04-30 1994-01-05 広栄化学工業株式会社 アミノメチルピリジンの製造法
DE3726993A1 (de) * 1987-08-13 1989-02-23 Bayer Ag Verfahren zur herstellung von 2-chlor-5-aminomethylpyridin
GB8924280D0 (en) * 1989-10-27 1989-12-13 Shell Int Research Butenone compounds,their preparation and their use as pesticides
GB2240051B (en) * 1990-01-18 1993-04-14 Pall Corp Cylindrical filters and their manufacture
JP3031727B2 (ja) * 1991-02-04 2000-04-10 広栄化学工業株式会社 α位に塩素原子を有するアミノメチルピリジン類の製造方法

Also Published As

Publication number Publication date
IL106192A0 (en) 1993-10-20
IL106192A (en) 1997-09-30
MX9303805A (es) 1994-02-28
EP0579970A2 (de) 1994-01-26
KR100282477B1 (ko) 2001-02-15
EP0579970B1 (de) 2000-03-08
CN1036585C (zh) 1997-12-03
ATE190306T1 (de) 2000-03-15
HU9301951D0 (en) 1993-09-28
HUT64519A (en) 1994-01-28
TW321637B (ko) 1997-12-01
DE59309966D1 (de) 2000-04-13
ES2142838T3 (es) 2000-05-01
CN1085213A (zh) 1994-04-13
EP0579970A3 (ko) 1994-03-16
JP3205648B2 (ja) 2001-09-04
HU213624B (en) 1997-08-28
DE4222152A1 (de) 1994-01-13
JPH0673007A (ja) 1994-03-15
US5453506A (en) 1995-09-26

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