KR950003273A - 클로로메틸피리딘의 제조방법 - Google Patents
클로로메틸피리딘의 제조방법 Download PDFInfo
- Publication number
- KR950003273A KR950003273A KR1019940015243A KR19940015243A KR950003273A KR 950003273 A KR950003273 A KR 950003273A KR 1019940015243 A KR1019940015243 A KR 1019940015243A KR 19940015243 A KR19940015243 A KR 19940015243A KR 950003273 A KR950003273 A KR 950003273A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- chloromethylpyridine
- halogen
- preparing
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
본 발명은 하기 일반식(Ⅱ)이 아미노메틸피리딘을 희석제의 존재하, 및 임의로 염화수소의 존재하에 -20℃ 내지 +50℃의 온도에서 니트로소화제 또는 디아조화제와 반응시킨 후, 통상적인 방법으로 후처리함을 특징으로 하여, 하기 일반식(Ⅰ)의 클로로메틸피리딘을 제조하는 방법에 관한 것이다.
상기식에서, n은 0,1,2 또는 3의 수를 나타내고, 일반식(Ⅰ)에서 X는 할로겐을 나타내며, 일반식(Ⅱ)에서 X는 아미노 또는 할로겐을 나타낸다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 일반식(Ⅱ)의 아미노메틸피리딘을 희석제의 존재하, 및 임의로 염화수소의 존재하에 -20℃ 내지 +50℃의 온도에서 니트로소화제 또는 디아조화제와 반응시킴을 특징으로 하여, 일반식(Ⅰ)의 클로로메틸피리딘을 제조하는 방법.상기식에서, n은 0,1,2 또는 3의 수를 나타내고, 일반식(Ⅰ)에서 X는 할로겐을 나타내며, 일반식(Ⅱ)에서 X는 아미노 또는 할로겐을 나타낸다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4322054A DE4322054A1 (de) | 1993-07-02 | 1993-07-02 | Verfahren zur Herstellung von Chlormethylpyridinen |
DEP4322054.1 | 1993-07-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950003273A true KR950003273A (ko) | 1995-02-16 |
KR100329100B1 KR100329100B1 (ko) | 2002-08-13 |
Family
ID=6491797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940015243A KR100329100B1 (ko) | 1993-07-02 | 1994-06-29 | 클로로메틸피리딘의제조방법 |
Country Status (10)
Country | Link |
---|---|
US (1) | US5442072A (ko) |
EP (1) | EP0632025B1 (ko) |
JP (1) | JP3488930B2 (ko) |
KR (1) | KR100329100B1 (ko) |
CN (1) | CN1085662C (ko) |
BR (1) | BR9402614A (ko) |
DE (2) | DE4322054A1 (ko) |
ES (1) | ES2150960T3 (ko) |
HU (1) | HU213626B (ko) |
TW (1) | TW253884B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2512344C1 (ru) | 2010-03-12 | 2014-04-10 | Ниппон Сода Ко., Лтд. | Соединение, содержащие кольцо пиридина, и способ получения галогенированного производного пиколина и производного тетразолилоксима |
CN102603620B (zh) * | 2012-01-13 | 2014-10-29 | 江苏中邦制药有限公司 | 一种氯甲基吡啶或其吡啶衍生物盐酸盐的合成方法 |
CN105622494B (zh) * | 2015-10-15 | 2019-01-15 | 南京红太阳生物化学有限责任公司 | 一种2-氯-5-甲基吡啶的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4111215A1 (de) * | 1991-04-06 | 1992-10-08 | Bayer Ag | Verfahren zur herstellung von 2-chlorpyridinen |
JP3078631B2 (ja) * | 1991-12-26 | 2000-08-21 | 広栄化学工業株式会社 | クロロメチルハロゲノピリジン類の製造方法 |
-
1993
- 1993-07-02 DE DE4322054A patent/DE4322054A1/de not_active Withdrawn
-
1994
- 1994-06-01 TW TW083105001A patent/TW253884B/zh active
- 1994-06-21 DE DE59409558T patent/DE59409558D1/de not_active Expired - Fee Related
- 1994-06-21 ES ES94109544T patent/ES2150960T3/es not_active Expired - Lifetime
- 1994-06-21 EP EP94109544A patent/EP0632025B1/de not_active Expired - Lifetime
- 1994-06-24 US US08/265,526 patent/US5442072A/en not_active Expired - Lifetime
- 1994-06-27 JP JP16575694A patent/JP3488930B2/ja not_active Expired - Fee Related
- 1994-06-29 KR KR1019940015243A patent/KR100329100B1/ko not_active IP Right Cessation
- 1994-07-01 HU HU9401981A patent/HU213626B/hu not_active IP Right Cessation
- 1994-07-01 BR BR9402614A patent/BR9402614A/pt not_active IP Right Cessation
- 1994-07-02 CN CN94108119A patent/CN1085662C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0717948A (ja) | 1995-01-20 |
DE59409558D1 (de) | 2000-11-30 |
US5442072A (en) | 1995-08-15 |
DE4322054A1 (de) | 1995-01-12 |
BR9402614A (pt) | 1995-04-04 |
JP3488930B2 (ja) | 2004-01-19 |
EP0632025A1 (de) | 1995-01-04 |
HU9401981D0 (en) | 1994-09-28 |
TW253884B (ko) | 1995-08-11 |
ES2150960T3 (es) | 2000-12-16 |
HU213626B (en) | 1997-08-28 |
HUT67669A (en) | 1995-04-28 |
KR100329100B1 (ko) | 2002-08-13 |
CN1098405A (zh) | 1995-02-08 |
CN1085662C (zh) | 2002-05-29 |
EP0632025B1 (de) | 2000-10-25 |
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