KR850002978A - 화학적 방법 - Google Patents

화학적 방법 Download PDF

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Publication number
KR850002978A
KR850002978A KR1019840006500A KR840006500A KR850002978A KR 850002978 A KR850002978 A KR 850002978A KR 1019840006500 A KR1019840006500 A KR 1019840006500A KR 840006500 A KR840006500 A KR 840006500A KR 850002978 A KR850002978 A KR 850002978A
Authority
KR
South Korea
Prior art keywords
compound
formula
chemical method
process according
dimethyl
Prior art date
Application number
KR1019840006500A
Other languages
English (en)
Inventor
미카엘 에드거 브리언 (외 1)
Original Assignee
데비드 마틴 워터스
스미스 클라인 앤드 프렌취 라보라토리스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데비드 마틴 워터스, 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 filed Critical 데비드 마틴 워터스
Publication of KR850002978A publication Critical patent/KR850002978A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

내용 없음

Description

화학적 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 일반식(Ⅶ)의 화합물을
    약 1.3 내지 약 2.5의 pH에서 비스(디메틸 아미노) 메탄의 유기용매와 반응시키는 것으로 구성된 일반식(Ⅵ)의 화합물을 제조하는 방법.
  2. pH 범위가 1.7 내지 2.3인 청구범위 제1항에 따른 방법.
  3. 디 클로로메탄에서 수행한 청구범위 제1항이나 제2항에 따른 방법.
  4. 염화수소 가스의 첨가로서 필요한 pH를 달성하는 청구범위 제1항 내지 제3항중의 어느 하나에 따른 방법.
  5. 일반식(Ⅵ)의 화합물 탈보호시켜 2-(2-(5-디메틸-아미노메틸푸란-2-일메틸티오)에틸아미노)-5-(2-하이드록시피리드-4-일메틸) 피리미딘-4-온에나 이들의 약제학상 허용가능한 염을 형성하는 청구범위 제1항에 따른 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840006500A 1983-10-21 1984-10-19 화학적 방법 KR850002978A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838328240A GB8328240D0 (en) 1983-10-21 1983-10-21 Chemical process
GB8328240 1983-10-21

Publications (1)

Publication Number Publication Date
KR850002978A true KR850002978A (ko) 1985-05-28

Family

ID=10550572

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840006500A KR850002978A (ko) 1983-10-21 1984-10-19 화학적 방법

Country Status (14)

Country Link
EP (1) EP0141560B1 (ko)
JP (1) JPS60109588A (ko)
KR (1) KR850002978A (ko)
AT (1) ATE40364T1 (ko)
AU (1) AU3424184A (ko)
CA (1) CA1261838A (ko)
DE (1) DE3476390D1 (ko)
DK (1) DK498684A (ko)
ES (1) ES536899A0 (ko)
GB (1) GB8328240D0 (ko)
GR (1) GR80702B (ko)
HU (1) HUT37422A (ko)
PT (1) PT79384B (ko)
ZA (1) ZA848180B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (ko) * 1978-02-13 1983-03-05 Smith Kline French Lab
ATE18045T1 (de) * 1982-07-20 1986-03-15 Smith Kline French Lab Verfahren zur herstellung von 2-(2-((5-dimethylaminomethyl)furan-2-ylmethylthio)|thylamino)-56-methylpyrid-3-yl-methyl)pyrimid-4-on.

Also Published As

Publication number Publication date
DE3476390D1 (en) 1989-03-02
ATE40364T1 (de) 1989-02-15
EP0141560A3 (en) 1986-02-05
ES8506305A1 (es) 1985-07-01
EP0141560B1 (en) 1989-01-25
ES536899A0 (es) 1985-07-01
ZA848180B (en) 1985-08-28
CA1261838A (en) 1989-09-26
AU3424184A (en) 1985-04-26
PT79384B (en) 1986-11-14
DK498684A (da) 1985-04-22
GB8328240D0 (en) 1983-11-23
JPS60109588A (ja) 1985-06-15
EP0141560A2 (en) 1985-05-15
DK498684D0 (da) 1984-10-18
HUT37422A (en) 1985-12-28
PT79384A (en) 1984-11-01
GR80702B (en) 1985-02-18

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