ES8506305A1 - Un procedimiento para preparar 2-(2-5-dimetilaminometilfuran-2-ilmetiltio)etilamino)-5-(2-metoxipirid-4-ilmetil)pirimidin-4-ona - Google Patents

Un procedimiento para preparar 2-(2-5-dimetilaminometilfuran-2-ilmetiltio)etilamino)-5-(2-metoxipirid-4-ilmetil)pirimidin-4-ona

Info

Publication number
ES8506305A1
ES8506305A1 ES536899A ES536899A ES8506305A1 ES 8506305 A1 ES8506305 A1 ES 8506305A1 ES 536899 A ES536899 A ES 536899A ES 536899 A ES536899 A ES 536899A ES 8506305 A1 ES8506305 A1 ES 8506305A1
Authority
ES
Spain
Prior art keywords
ethylamino
ylmethyl
dimethylaminomethylfuran
ylmethylthio
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536899A
Other languages
English (en)
Other versions
ES536899A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES536899A0 publication Critical patent/ES536899A0/es
Publication of ES8506305A1 publication Critical patent/ES8506305A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR 2-2-(5-DIMETILAMINOMETILFURAN-2-ILMETILTIO)ETILAMINO-5-(2-METOXIPIRID-4-ILMETIL)PIRIMIDIN-4-ONA.COMPRENDE HACER REACCIONAR 2-2-(FURAN-2-ILMETILTIO)ETILAMINO-5-(2-METOXIPIRID-4-ILMETIL)PIRIMIDIN-4-ONA CON UNA SOLUCION ORGANICA DE BIS(DIMETILAMINO)METANO A UN PH DE APROXIMADAMENTE 1,3 A APROXIMADAMENTE 2,5. EL PRODUCTO ES UN ANTAGONISTA DEL RECEPTOR H2 Y TAMBIEN ES VALIOSO PARA FORMAR 2-2-(5-DIMETILAMINOMETILFURAN-2-ILMETILTIO)ETILAMINO-5-(2-HIDROXIPIRID-4-ILMETIL)-PIRIMIDIN-4-ONA POR DESPROTECCION.
ES536899A 1983-10-21 1984-10-19 Un procedimiento para preparar 2-(2-5-dimetilaminometilfuran-2-ilmetiltio)etilamino)-5-(2-metoxipirid-4-ilmetil)pirimidin-4-ona Expired ES8506305A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838328240A GB8328240D0 (en) 1983-10-21 1983-10-21 Chemical process

Publications (2)

Publication Number Publication Date
ES536899A0 ES536899A0 (es) 1985-07-01
ES8506305A1 true ES8506305A1 (es) 1985-07-01

Family

ID=10550572

Family Applications (1)

Application Number Title Priority Date Filing Date
ES536899A Expired ES8506305A1 (es) 1983-10-21 1984-10-19 Un procedimiento para preparar 2-(2-5-dimetilaminometilfuran-2-ilmetiltio)etilamino)-5-(2-metoxipirid-4-ilmetil)pirimidin-4-ona

Country Status (14)

Country Link
EP (1) EP0141560B1 (es)
JP (1) JPS60109588A (es)
KR (1) KR850002978A (es)
AT (1) ATE40364T1 (es)
AU (1) AU3424184A (es)
CA (1) CA1261838A (es)
DE (1) DE3476390D1 (es)
DK (1) DK498684A (es)
ES (1) ES8506305A1 (es)
GB (1) GB8328240D0 (es)
GR (1) GR80702B (es)
HU (1) HUT37422A (es)
PT (1) PT79384B (es)
ZA (1) ZA848180B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (es) * 1978-02-13 1983-03-05 Smith Kline French Lab
ATE18045T1 (de) * 1982-07-20 1986-03-15 Smith Kline French Lab Verfahren zur herstellung von 2-(2-((5-dimethylaminomethyl)furan-2-ylmethylthio)|thylamino)-56-methylpyrid-3-yl-methyl)pyrimid-4-on.

Also Published As

Publication number Publication date
EP0141560B1 (en) 1989-01-25
DK498684D0 (da) 1984-10-18
ES536899A0 (es) 1985-07-01
KR850002978A (ko) 1985-05-28
HUT37422A (en) 1985-12-28
GR80702B (en) 1985-02-18
EP0141560A2 (en) 1985-05-15
DE3476390D1 (en) 1989-03-02
JPS60109588A (ja) 1985-06-15
CA1261838A (en) 1989-09-26
ZA848180B (en) 1985-08-28
ATE40364T1 (de) 1989-02-15
GB8328240D0 (en) 1983-11-23
AU3424184A (en) 1985-04-26
EP0141560A3 (en) 1986-02-05
PT79384B (en) 1986-11-14
DK498684A (da) 1985-04-22
PT79384A (en) 1984-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603