KR930000514A - 7-아자이소인돌리닐-퀴놀론- 및 -나프티리돈카르복실산 유도체 - Google Patents
7-아자이소인돌리닐-퀴놀론- 및 -나프티리돈카르복실산 유도체 Download PDFInfo
- Publication number
- KR930000514A KR930000514A KR1019920011212A KR920011212A KR930000514A KR 930000514 A KR930000514 A KR 930000514A KR 1019920011212 A KR1019920011212 A KR 1019920011212A KR 920011212 A KR920011212 A KR 920011212A KR 930000514 A KR930000514 A KR 930000514A
- Authority
- KR
- South Korea
- Prior art keywords
- methyl
- carbon atoms
- represents hydrogen
- alkyl
- hydroxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002253 acid Substances 0.000 title claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 18
- 239000001257 hydrogen Substances 0.000 claims 18
- 125000004432 carbon atom Chemical group C* 0.000 claims 14
- -1 alkali metal salts Chemical class 0.000 claims 13
- 150000002431 hydrogen Chemical class 0.000 claims 10
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 8
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 6
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 5
- 229910052731 fluorine Inorganic materials 0.000 claims 5
- 239000011737 fluorine Substances 0.000 claims 5
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 229910052801 chlorine Inorganic materials 0.000 claims 4
- 239000000460 chlorine Substances 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical class NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims 3
- 229910052783 alkali metal Inorganic materials 0.000 claims 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 3
- 229910052794 bromium Inorganic materials 0.000 claims 3
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 150000004677 hydrates Chemical class 0.000 claims 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000004777 2-fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 150000003378 silver Chemical class 0.000 claims 2
- PXEWHFYYGISVCY-UHFFFAOYSA-N 2,3-dihydro-1h-pyrrolo[3,4-b]pyrazine Chemical compound N1CCN=C2C=NC=C21 PXEWHFYYGISVCY-UHFFFAOYSA-N 0.000 claims 1
- 125000004215 2,4-difluorophenyl group Chemical group [H]C1=C([H])C(*)=C(F)C([H])=C1F 0.000 claims 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
- SJMNQXLXIIXDDS-UHFFFAOYSA-N 6,7-dihydro-5h-pyrrolo[3,4-b]pyridine Chemical compound C1=CC=C2CNCC2=N1 SJMNQXLXIIXDDS-UHFFFAOYSA-N 0.000 claims 1
- YKOHISXKVNHKPQ-UHFFFAOYSA-N 8-chloro-1-cyclopropyl-6-fluoro-7-(5-methyl-3,4,6,7-tetrahydro-1h-pyrrolo[3,4-c]pyridin-2-yl)-4-oxoquinoline-3-carboxylic acid Chemical compound C1N(C)CCC(C2)=C1CN2C(C=1Cl)=C(F)C=C(C(C(C(O)=O)=C2)=O)C=1N2C1CC1 YKOHISXKVNHKPQ-UHFFFAOYSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000004663 dialkyl amino group Chemical group 0.000 claims 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims 1
- PCBKEVNPKSZQFU-UHFFFAOYSA-N ethyl 5,7-dihydropyrrolo[3,4-b]pyridine-6-carboxylate Chemical compound C1=CN=C2CN(C(=O)OCC)CC2=C1 PCBKEVNPKSZQFU-UHFFFAOYSA-N 0.000 claims 1
- HPYCOEHAQNLFFP-UHFFFAOYSA-N ethyl n-prop-2-ynyl-n-(pyrazin-2-ylmethyl)carbamate Chemical compound CCOC(=O)N(CC#C)CC1=CN=CC=N1 HPYCOEHAQNLFFP-UHFFFAOYSA-N 0.000 claims 1
- UOVGEMRIXFIRSE-UHFFFAOYSA-N ethyl n-prop-2-ynyl-n-(pyrimidin-2-ylmethyl)carbamate Chemical compound CCOC(=O)N(CC#C)CC1=NC=CC=N1 UOVGEMRIXFIRSE-UHFFFAOYSA-N 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- XMSZANIMCDLNKA-UHFFFAOYSA-N methyl hypofluorite Chemical compound COF XMSZANIMCDLNKA-UHFFFAOYSA-N 0.000 claims 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 claims 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4121214.2 | 1991-06-27 | ||
| DE4121214A DE4121214A1 (de) | 1991-06-27 | 1991-06-27 | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR930000514A true KR930000514A (ko) | 1993-01-15 |
Family
ID=6434855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920011212A Withdrawn KR930000514A (ko) | 1991-06-27 | 1992-06-26 | 7-아자이소인돌리닐-퀴놀론- 및 -나프티리돈카르복실산 유도체 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5312823A (enExample) |
| EP (1) | EP0520277A3 (enExample) |
| JP (1) | JPH05213947A (enExample) |
| KR (1) | KR930000514A (enExample) |
| CN (1) | CN1068114A (enExample) |
| AU (2) | AU647627B2 (enExample) |
| CA (1) | CA2072207A1 (enExample) |
| CZ (1) | CZ192892A3 (enExample) |
| DE (1) | DE4121214A1 (enExample) |
| FI (1) | FI922953A7 (enExample) |
| HU (1) | HUT61545A (enExample) |
| IE (1) | IE922099A1 (enExample) |
| IL (1) | IL102288A0 (enExample) |
| MX (1) | MX9203228A (enExample) |
| NO (1) | NO922291L (enExample) |
| TW (1) | TW209218B (enExample) |
| ZA (1) | ZA924743B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100371883B1 (ko) * | 1994-10-04 | 2003-03-29 | 바이엘 악티엔게젤샤프트 | 퀴놀론-및나프티리돈카르복실산유도체 |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4121214A1 (de) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
| AU4272793A (en) * | 1993-04-24 | 1994-11-21 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and process for preparing the same |
| DE4339134A1 (de) * | 1993-11-16 | 1995-05-18 | Bayer Ag | 1-(2-Fluorcyclopropyl)-chinolon- und -naphthyridoncarbonsäure-Derivate |
| KR950018003A (ko) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | 신규한 퀴놀론 유도체 및 그의 제조 방법 |
| DE4427530A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäure-Derivate |
| DE19500792A1 (de) * | 1995-01-13 | 1996-07-18 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäure-Derivate |
| US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| CA2405532A1 (en) | 2001-02-07 | 2002-08-22 | Ortho-Mcneil Pharmaceutical, Inc. | Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods |
| KR101294467B1 (ko) | 2005-07-25 | 2013-09-09 | 인터뮨, 인크. | Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제 |
| FR2891274B1 (fr) * | 2005-09-27 | 2007-11-23 | Pierre Fabre Medicament Sa | Procede de preparation du (3-chloro-4-fluoro-phenyl)-(4- fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone et nouveaux derives pyrimidiniques intermediaires. |
| CN102443015A (zh) * | 2010-10-13 | 2012-05-09 | 南京明生医药技术有限公司 | 一种7-取代喹啉羧酸衍生物及其制备方法和在抗菌抗结核上的应用 |
| AR095079A1 (es) | 2013-03-12 | 2015-09-16 | Hoffmann La Roche | Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo |
| CN103351348A (zh) * | 2013-07-15 | 2013-10-16 | 黄河三角洲京博化工研究院有限公司 | 一种2-甲胺基嘧啶盐酸盐的合成方法 |
| KR20160087900A (ko) | 2013-11-26 | 2016-07-22 | 에프. 호프만-라 로슈 아게 | 신규한 옥타하이드로-사이클로부타[1,2-c；3,4-c'']다이피롤-2-일 |
| SI3102576T1 (sl) | 2014-02-03 | 2019-08-30 | Vitae Pharmaceuticals, Llc | Inhibitorji dihidropirolopiridina ROR-gama |
| SI3122750T1 (sl) | 2014-03-26 | 2019-12-31 | F. Hoffmann-La Roche Ag | Biciklične spojine kot zaviralci proizvodnje avtotaksina (ATX) in lizofosfatidne kisline (LPA) |
| WO2016046837A1 (en) * | 2014-09-22 | 2016-03-31 | Cadila Healthcare Limited | An improved process for preparation of pyrrolo[3,4- c] pyrrole compounds and intermediates thereof |
| BR112017007460A2 (pt) | 2014-10-14 | 2017-12-19 | Vitae Pharmaceuticals Inc | inibidores de di-hidropirrolopiridina de ror-gama |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
| WO2016183741A1 (en) | 2015-05-15 | 2016-11-24 | Merck Sharp & Dohme Corp. | Pyrimidinone amide compounds as pde2 inhibitors |
| ES2856931T3 (es) | 2015-08-05 | 2021-09-28 | Vitae Pharmaceuticals Llc | Moduladores de ROR-gamma |
| JP6886967B2 (ja) | 2015-09-04 | 2021-06-16 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | フェノキシメチル誘導体 |
| CN107635995B (zh) | 2015-09-24 | 2022-08-19 | 豪夫迈·罗氏有限公司 | 作为atx抑制剂的二环化合物 |
| AU2016328365B2 (en) | 2015-09-24 | 2020-04-23 | F. Hoffmann-La Roche Ag | New bicyclic compounds as dual ATX/CA inhibitors |
| JP6877413B2 (ja) * | 2015-09-24 | 2021-05-26 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 二重ａｔｘ／ｃａ阻害剤としての新規な二環式化合物 |
| WO2017087608A1 (en) | 2015-11-20 | 2017-05-26 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| WO2018167113A1 (en) | 2017-03-16 | 2018-09-20 | F. Hoffmann-La Roche Ag | New bicyclic compounds as atx inhibitors |
| EP3596059B1 (en) | 2017-03-16 | 2024-04-24 | F. Hoffmann-La Roche AG | Heterocyclic compounds useful as dual atx/ca inhibitors |
| PT3448859T (pt) | 2017-03-20 | 2019-10-25 | Forma Therapeutics Inc | Composições de pirrolopirrole como ativadores de piruvato quinase (pkr). |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| KR20200053481A (ko) | 2017-07-24 | 2020-05-18 | 비타이 파마슈티컬즈, 엘엘씨 | RORγ의 억제제 |
| US12053458B2 (en) | 2018-09-19 | 2024-08-06 | Novo Nordisk Health Care Ag | Treating sickle cell disease with a pyruvate kinase R activating compound |
| ES2989438T3 (es) | 2018-09-19 | 2024-11-26 | Novo Nordisk Healthcare Ag | Activación de la piruvato cinasa R |
| CN109942488A (zh) * | 2019-04-04 | 2019-06-28 | 山东省联合农药工业有限公司 | 一种喹啉羧酸酯类化合物及其制备方法与用途 |
| CN114615977B (zh) | 2019-09-19 | 2025-01-14 | 诺沃挪第克健康护理股份公司 | 丙酮酸激酶r(pkr)活化组合物 |
| US12128035B2 (en) | 2021-03-19 | 2024-10-29 | Novo Nordisk Health Care Ag | Activating pyruvate kinase R |
| CN115251064B (zh) * | 2021-04-29 | 2023-08-29 | 山东省联合农药工业有限公司 | 一种杀菌杀虫组合物及其应用 |
| CN113307768B (zh) * | 2021-04-29 | 2023-12-12 | 中国农业科学院兰州畜牧与兽药研究所 | 喹诺酮类衍生物及其制备方法和用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| NZ208470A (en) * | 1983-07-18 | 1988-06-30 | Abbott Lab | 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such |
| EP0154780B1 (en) * | 1984-01-26 | 1990-04-11 | Abbott Laboratories | Quinoline antibacterial compounds |
| NZ210847A (en) * | 1984-01-26 | 1988-02-29 | Abbott Lab | Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions |
| DE3420743A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| WO1989005643A1 (en) * | 1987-12-18 | 1989-06-29 | Pfizer Inc. | Heterocyclic-substituted quinoline-carboxylic acids |
| JPH0262875A (ja) * | 1988-05-23 | 1990-03-02 | Wakunaga Pharmaceut Co Ltd | 新規イソインドリン誘導体 |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| KR910009333B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| KR910009330B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| DE4121214A1 (de) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
| DE4123918A1 (de) * | 1991-07-19 | 1993-01-21 | Bayer Ag | 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren |
| KR930703292A (ko) * | 1991-12-27 | 1993-11-29 | 쿠사이 요시히로 | 신규 퀴놀론 유도체 또는 그의 염 및 이 화합물을 함유하는 항균제 |
| TW209865B (enExample) * | 1992-01-10 | 1993-07-21 | Bayer Ag |
-
1991
- 1991-06-27 DE DE4121214A patent/DE4121214A1/de not_active Withdrawn
-
1992
- 1992-05-23 TW TW081104032A patent/TW209218B/zh active
- 1992-06-04 AU AU18030/92A patent/AU647627B2/en not_active Ceased
- 1992-06-08 CN CN92104542A patent/CN1068114A/zh active Pending
- 1992-06-11 NO NO92922291A patent/NO922291L/no unknown
- 1992-06-15 EP EP19920110043 patent/EP0520277A3/de not_active Withdrawn
- 1992-06-19 US US07/901,056 patent/US5312823A/en not_active Expired - Fee Related
- 1992-06-23 CZ CS921928A patent/CZ192892A3/cs unknown
- 1992-06-24 CA CA002072207A patent/CA2072207A1/en not_active Abandoned
- 1992-06-24 MX MX9203228A patent/MX9203228A/es unknown
- 1992-06-24 IL IL102288A patent/IL102288A0/xx unknown
- 1992-06-25 JP JP4190249A patent/JPH05213947A/ja active Pending
- 1992-06-25 FI FI922953A patent/FI922953A7/fi unknown
- 1992-06-26 KR KR1019920011212A patent/KR930000514A/ko not_active Withdrawn
- 1992-06-26 ZA ZA924743A patent/ZA924743B/xx unknown
- 1992-06-26 HU HU9202145A patent/HUT61545A/hu unknown
- 1992-07-01 IE IE209992A patent/IE922099A1/en not_active Application Discontinuation
-
1994
- 1994-01-06 AU AU53040/94A patent/AU5304094A/en not_active Abandoned
- 1994-02-18 US US08/199,371 patent/US5371090A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100371883B1 (ko) * | 1994-10-04 | 2003-03-29 | 바이엘 악티엔게젤샤프트 | 퀴놀론-및나프티리돈카르복실산유도체 |
Also Published As
| Publication number | Publication date |
|---|---|
| HUT61545A (en) | 1993-01-28 |
| IE922099A1 (en) | 1992-12-30 |
| NO922291D0 (no) | 1992-06-11 |
| CN1068114A (zh) | 1993-01-20 |
| US5371090A (en) | 1994-12-06 |
| ZA924743B (en) | 1993-03-31 |
| NO922291L (no) | 1992-12-28 |
| AU1803092A (en) | 1993-01-07 |
| DE4121214A1 (de) | 1993-01-14 |
| TW209218B (enExample) | 1993-07-11 |
| HU9202145D0 (en) | 1992-10-28 |
| CZ192892A3 (en) | 1993-01-13 |
| AU5304094A (en) | 1994-03-03 |
| EP0520277A3 (en) | 1993-01-13 |
| EP0520277A2 (de) | 1992-12-30 |
| FI922953A0 (fi) | 1992-06-25 |
| FI922953A7 (fi) | 1992-12-28 |
| IL102288A0 (en) | 1993-01-14 |
| AU647627B2 (en) | 1994-03-24 |
| CA2072207A1 (en) | 1992-12-28 |
| MX9203228A (es) | 1992-12-01 |
| JPH05213947A (ja) | 1993-08-24 |
| US5312823A (en) | 1994-05-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR930000514A (ko) | 7-아자이소인돌리닐-퀴놀론- 및 -나프티리돈카르복실산 유도체 | |
| KR950014108A (ko) | 복소환 화합물, 그의 제조방법 및 용도 | |
| UA19304A (uk) | Фуhгіцидhий засіб | |
| KR940018380A (ko) | 퀴놀론-및 나프티리돈카르복실산 유도체 | |
| KR870003100A (ko) | 벤즈이미다졸 유도체 | |
| IE811085L (en) | Pyridoxine derivatives | |
| IE812683L (en) | Thieno-pyridine derivatives | |
| SE7710873L (sv) | Nya 1h-pyrazolo(3,4-b)pyridiner | |
| KR850001198A (ko) | 카복실산 유도체의 제조방법 | |
| KR860001808A (ko) | 이미다조〔1,5-a〕피리미딘 유도체의 제조방법 | |
| ES2063058T3 (es) | N,n'-carbonil-bis-(4-etil-2,3-dioxo)-piperazina, proceso para su preparacion y uso de la misma. | |
| AU579869B2 (en) | 4-amino-8-alkylthio-2-piperazino-pyrimido ``5,4-d`` pyrimidines | |
| ATE29721T1 (de) | 5-(4-vinyl- oder 4-ethynylbenzoyl)-1,2-dihydro-3h-pyrrolo-(1,2-a -pyrrol-1-carbosaeure und deren derivate. | |
| AU556922B2 (en) | Pyridobenzodiazepinone derivatives | |
| KR930021641A (ko) | 7-옥소-7H-피리도[1,2,3-d,e][1,4]벤족사진-6-카르복실산 및 에스테르 | |
| AU562629B2 (en) | Terrahydro thiophen - and tetrahydrothiopyran-derivatives | |
| KR850002094A (ko) | 나프탈레닐 이미다조피리딘 및 그의 유도체의 제조방법 | |
| KR950014114A (ko) | 1-(2-플루오로시클로프로필)-퀴놀론카르복실산 및 1-(2-플루오로시클로프로필)-나프티리돈카르복실산 유도체 | |
| IE791184L (en) | IMIDAZO £1,2-a| IMIDAZOLE DERIVATIVES | |
| AU551901B2 (en) | Substituted thienobenzodiazepinones | |
| GB2112774B (en) | Imidazole derivatives | |
| SE8703494D0 (sv) | Mellanprodukter anvendbara vid framstellning av 2-tiofen-ettiksyraderivat | |
| HUT50833A (en) | Process for producing indolo/3,2-1-de/ /1,4/-oxazino/2,3,4-ij/ /1,5/-naphthyridine derivatives | |
| JPS52122391A (en) | Novel penicillins | |
| JPS56135488A (en) | Novel preparative method of cephalosporanic acid derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19920626 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |