KR930703292A - 신규 퀴놀론 유도체 또는 그의 염 및 이 화합물을 함유하는 항균제 - Google Patents
신규 퀴놀론 유도체 또는 그의 염 및 이 화합물을 함유하는 항균제Info
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- KR930703292A KR930703292A KR1019930702531A KR930702531A KR930703292A KR 930703292 A KR930703292 A KR 930703292A KR 1019930702531 A KR1019930702531 A KR 1019930702531A KR 930702531 A KR930702531 A KR 930702531A KR 930703292 A KR930703292 A KR 930703292A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
하기 일반식(1)
〔식중, R1은 수소 원자, 할로겐 원자, 또는 카르복시 보호기를 나타내며, R2는 수소 원자, 할로겐 원자, 또는 저급 알킬기를 나타내며, X는 수소 원자 또는 할로겐 원자를 나타내고, Y는 할로겐 원자, 치환기를 가져도 좋은 환상 아미노기, 치환기를 가져도 좋은 시클로 저급 알케닐기 또는 식 R3-(CH2)m-A(여기서, R3는 수소 원자 또는 치환기 아미노기를 나타내고, A는 탄소원자 또는 유황원자를 나타내고, m은 0~3의 수를 나타낸다)로 표시되는 기를 나타내고, Z는 질소 원자 또는 C-R4(여기서, R4는 수소 원자 또는 할로겐 원자를 나타낸다)를 나타내고, W는 3개 이상의 헤테로 원자를 가지며, 그 중 적어도 2개의 헤테로 원자가 질소 원자인 치환기를 가져도 좋은 5원 복소환식 기를 나타내고, n은 0~2의 수를 나타낸다〕로 표시되는 퀴놀린 유도체 또는 그의 염 및 이 화합물을 유효성분으로 하는 항균제.
상기 화합물은 강한 항균 작용을 나타내며, 또한 안전성도 높기 때문에 인체 및 동물용 의약품, 어병약(魚病藥), 농약, 식품보존제등에 유용하다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 하기 일반식(1)〔식중, R1은 수소 원자, 할로겐 원자, 또는 카르복시 보호기를 나타내며, R2는 수소 원자, 할로겐 원자, 또는 저급 알킬기를 나타내며, X는 수소 원자 또는 할로겐 원자를 나타내고, Y는 할로겐 원자, 치환기를 가져도 좋은 환상 아미노기, 치환기를 가져도 좋은 시클로 저급 알케닐기 또는 식 R3-(CH2)m-A(여기서, R3는 수소 원자 또는 치환기 아미노기를 나타내고, A는 탄소원자 또는 유황원자를 나타내고, m은 0~3의 수를 나타낸다)로 표시되는 기를 나타내고, Z는 질소 원자 또는 C-R4(여기서, R4는 수소 원자 또는 할로겐 원자를 나타낸다)를 나타내고, W는 3개 이상의 헤테로 원자를 가지며, 그 중 적어도 2개의 헤테로 원자가 질소 원자인 치환기를 가져도 좋은 5원 복소환식 기를 나타내고, n은 0~2의 수를 나타낸다〕으로 표시되는 퀴놀론유도체 또는 그의 염.
- Y로 표시되는 치환기를 가져도 좋은 환상아미노기가 질소원자 1개를 갖는 포화 또는 불포화 단환식 3~7원의 환상아미노기, 질소원자 2개를 갖는 포화 또는 불포화의 단환식 3~7원의 환상아미노기 또는 산소원자 및 유황원자로 부터 선택된 할로겐원자를 갖는 포화 또는 불포화의 단환식 3~7원의 환상아미노기인 청구범위 제1항 기재의 퀴놀론유도체 또는 그의 염.
- W가 각각 치환기를 가져도 좋은 티아디아졸릴기, 트리아졸릴기, 옥사디아졸릴기, 또는 테트라졸릴기인 청구범위 제1항 기재의 퀴놀론 유도체 또는 그의 염.
- 청구범위 제1항 기재의 퀴놀론유도체 또는 그의 염을 유효성분으로 하는 항균제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP34657791 | 1991-12-27 | ||
JP91-346577 | 1991-12-27 | ||
PCT/JP1992/001712 WO1993013091A1 (en) | 1991-12-27 | 1992-12-25 | Novel quinolone derivative or salt thereof and antibacterial containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
KR930703292A true KR930703292A (ko) | 1993-11-29 |
Family
ID=18384366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019930702531A KR930703292A (ko) | 1991-12-27 | 1992-12-25 | 신규 퀴놀론 유도체 또는 그의 염 및 이 화합물을 함유하는 항균제 |
Country Status (4)
Country | Link |
---|---|
US (1) | US5412098A (ko) |
EP (1) | EP0596126A4 (ko) |
KR (1) | KR930703292A (ko) |
WO (1) | WO1993013091A1 (ko) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4121214A1 (de) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
DE4431122A1 (de) * | 1994-09-01 | 1996-03-07 | Bayer Ag | Neue Thiazolo[3,2-a]chinolin- und -naphthyridinderivate |
SK286420B6 (sk) * | 1997-09-15 | 2008-09-05 | The Procter & Gamble Company | Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie |
AU2001253418A1 (en) * | 2000-04-12 | 2001-10-30 | Smith Kline Beecham Corporation | Compounds and methods |
SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
JP2004515548A (ja) * | 2000-12-14 | 2004-05-27 | ザ プロクター アンド ギャンブル カンパニー | 抗微生物キノロン |
AU3089302A (en) | 2000-12-14 | 2002-06-24 | Procter & Gamble | Antimicrobial 2-pyridones, their compositions and uses |
US8163769B2 (en) * | 2002-03-12 | 2012-04-24 | Abbott Laboratories | Antibacterial compounds |
WO2004091627A2 (en) * | 2003-04-07 | 2004-10-28 | Cylene Pharmaceuticals, Inc. | Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs |
WO2005100349A2 (en) * | 2004-04-13 | 2005-10-27 | Icagen, Inc. | Polycyclic pyridines as potassium ion channel modulators |
EP1742904B1 (en) * | 2004-05-06 | 2012-10-31 | The Regents of The University of California | Substituted enaminones, their derivatives and uses thereof |
US7412791B2 (en) * | 2004-12-20 | 2008-08-19 | Lsi Industries, Inc. | Adjustable menu panel |
US7563805B2 (en) | 2005-05-19 | 2009-07-21 | Daiichi Pharmaceutical Co., Ltd. | Tri-, tetra-substituted-3-aminopyrrolidine derivative |
BRPI0709772B8 (pt) * | 2006-03-28 | 2021-05-25 | The Protecter & Gamble Company | sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico |
CA2647454A1 (en) * | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | A coupling process for preparing quinolone intermediates |
CN102627630A (zh) * | 2012-03-16 | 2012-08-08 | 西南大学 | 喹诺酮类化合物及其制备方法和应用 |
US11286255B2 (en) | 2017-03-24 | 2022-03-29 | Wakunaga Pharmaceutical Co., Ltd. | Pyridone carboxylic acid derivative or salt thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2808070A1 (de) * | 1978-02-24 | 1979-08-30 | Bayer Ag | Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten |
US4617308A (en) * | 1985-01-25 | 1986-10-14 | Warner-Lambert Company | 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents |
JPS61251667A (ja) * | 1985-04-30 | 1986-11-08 | Otsuka Pharmaceut Co Ltd | ベンゾヘテロ環化合物 |
JPS6233176A (ja) * | 1985-08-05 | 1987-02-13 | Toyama Chem Co Ltd | 1,4−ジヒドロ−4−オキソナフチリジン誘導体およびその塩 |
JP2704428B2 (ja) * | 1988-06-15 | 1998-01-26 | 富山化学工業株式会社 | キノロンカルボン酸誘導体またはその塩 |
EP0390215B1 (en) * | 1989-03-30 | 1995-06-07 | Wakunaga Seiyaku Kabushiki Kaisha | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same |
CA2012681A1 (en) * | 1989-03-31 | 1990-09-30 | Masayasu Okuhira | Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same |
US5137892A (en) * | 1990-12-12 | 1992-08-11 | Abbott Laboratories | Quinoline, naphthyridine and pyridobenzoxazine derivatives |
-
1992
- 1992-12-25 US US08/104,137 patent/US5412098A/en not_active Expired - Fee Related
- 1992-12-25 KR KR1019930702531A patent/KR930703292A/ko not_active Application Discontinuation
- 1992-12-25 EP EP19930900445 patent/EP0596126A4/en not_active Withdrawn
- 1992-12-25 WO PCT/JP1992/001712 patent/WO1993013091A1/ja not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US5412098A (en) | 1995-05-02 |
WO1993013091A1 (en) | 1993-07-08 |
EP0596126A1 (en) | 1994-05-11 |
EP0596126A4 (en) | 1994-06-08 |
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