ATE358484T1 - Antidiabetische medikamente - Google Patents

Antidiabetische medikamente

Info

Publication number
ATE358484T1
ATE358484T1 AT99926903T AT99926903T ATE358484T1 AT E358484 T1 ATE358484 T1 AT E358484T1 AT 99926903 T AT99926903 T AT 99926903T AT 99926903 T AT99926903 T AT 99926903T AT E358484 T1 ATE358484 T1 AT E358484T1
Authority
AT
Austria
Prior art keywords
substituted
group
unsubstituted
hydrogen atom
lower alkyl
Prior art date
Application number
AT99926903T
Other languages
English (en)
Inventor
Junichi Shimada
Yoshihisa Ohta
Kotaro Takasaki
Miho Suda
Hideaki Kusaka
Hiroshi Yano
Satoshi Nakanishi
Yuzuru Matsuda
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE358484T1 publication Critical patent/ATE358484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99926903T 1998-07-02 1999-07-02 Antidiabetische medikamente ATE358484T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18770598 1998-07-02

Publications (1)

Publication Number Publication Date
ATE358484T1 true ATE358484T1 (de) 2007-04-15

Family

ID=16210732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99926903T ATE358484T1 (de) 1998-07-02 1999-07-02 Antidiabetische medikamente

Country Status (8)

Country Link
US (1) US6489331B1 (de)
EP (1) EP1092435B1 (de)
AT (1) ATE358484T1 (de)
AU (1) AU4396899A (de)
CA (1) CA2336412C (de)
DE (1) DE69935718T2 (de)
ES (1) ES2284256T3 (de)
WO (1) WO2000001388A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL149487A0 (en) 1999-11-12 2002-11-10 Biogen Inc Polycycloalkylpurine derivatives and pharmaceutical compositions containing the same
DK1230241T3 (da) 1999-11-12 2007-06-04 Biogen Idec Inc Adenosinreceptorantagonister og fremgangsmåder til fremstilling og anvendelse af samme
ATE289311T1 (de) * 1999-12-24 2005-03-15 Kyowa Hakko Kogyo Kk Kondensierte purinderivate
UA75625C2 (en) * 2000-12-01 2006-05-15 Biogen Inc Condensed purine derivatives as a1 adenosine receptor antagonists
JP4450628B2 (ja) 2002-03-22 2010-04-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルトランスフェラーゼインヒビターとして使用するためのベンジルイミダゾリル置換２−キノリンおよびキナゾリン誘導体
AU2003231538A1 (en) * 2002-05-17 2003-12-02 Kyowa Hakko Kogyo Co., Ltd. Method of searching substane having antidiabetic activity
AU2003234929A1 (en) * 2002-05-17 2003-12-02 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for diabetes
WO2004011469A1 (ja) * 2002-07-26 2004-02-05 Kyowa Hakko Kogyo Co., Ltd. 細胞分化誘導剤
CA2498944C (en) 2002-09-19 2011-05-17 Yasushi Kohno Amino alcohol derivatives, salts thereof and immunosuppressive agents
CN1777608A (zh) * 2003-04-25 2006-05-24 协和发酵工业株式会社 稠合嘧啶衍生物
BRPI0513110A (pt) * 2004-07-16 2008-04-29 Kyorin Seiyaku Kk medicamento compreendendo composto sulfeto diaril ou composto éter diaril tendo uma estrutura 2-amina-1, 3-propanediol tendo uma atividade de redução de linfócitos perifericamente circulante, em combinação com um agente imunosupressivo e/ou um agente antiinflamatório e método de expressão de prevenção do efeito secundário
RU2376285C2 (ru) * 2004-10-12 2009-12-20 Киорин Фармасьютикал Ко., Лтд. Процесс получения гидрохлорида 2-амино-2-[2-[4-(3-бензилоксифенилтио)-2-хлорфенилэтил]-1,3-пропандиола] и его гидратов, а также промежуточные продукты их получения
BRPI0617077A2 (pt) * 2005-10-07 2015-01-06 Kyorin Seiyaku Kk Agente terapêutico para tratamento de doenças do fígado contendo 2-amina-1, 3-propanediol derivativo como ingrediente ativo, e método para tratamento de doenças do fígado
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
KR20090025262A (ko) * 2006-06-23 2009-03-10 인사이트 코포레이션 Ｈｍ７４ａ 아고니스트로서 푸리논 유도체
CN101479273B (zh) * 2006-06-23 2011-11-30 英赛特股份有限公司 作为hm74a激动剂的嘌呤酮衍生物
CN101466714B (zh) 2006-06-23 2013-02-06 英赛特股份有限公司 作为hm74a激动剂的嘌呤酮衍生物
SG174029A1 (en) * 2006-08-08 2011-09-29 Kyorin Seiyaku Kk Aminoalcohol derivative and immunosuppressant containing the same as active ingredient
US8232319B2 (en) * 2006-08-08 2012-07-31 Kyorin Pharmaceutical Co., Ltd. Amino phosphate derivative and S1P receptor modulator having same as an active ingredient
JP4337898B2 (ja) * 2007-03-29 2009-09-30 セイコーエプソン株式会社 半導体装置
WO2009099174A1 (ja) 2008-02-07 2009-08-13 Kyorin Pharmaceutical Co., Ltd. アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤
EP2145621A1 (de) * 2008-07-16 2010-01-20 Stephan Lück Verhinderung der Dehydrierung und Reduzierung der gluconeogenetischen Verluste von Aminosäuren durch Propan-1,2,3-Triol
CN103492359B (zh) * 2011-04-02 2015-11-25 中国人民解放军军事医学科学院毒物药物研究所 氨基苯丙醇类化合物及其用于制备免疫抑制剂的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2028235C (en) 1989-10-20 1997-01-21 Fumio Suzuki Condensed purine derivatives
GB9015914D0 (en) * 1990-07-19 1990-09-05 Wellcome Found Heterocyclic compounds
JP3204880B2 (ja) 1995-07-25 2001-09-04 株式会社バーテックススタンダード デジタルフィルタ
WO1998015555A1 (en) * 1996-10-07 1998-04-16 Kyowa Hakko Kogyo Co., Ltd. Fused purine derivatives
JP4354016B2 (ja) * 1996-11-29 2009-10-28 株式会社メディサイエンスプラニング 新規プリン誘導体およびこれを含む医薬組成物

Also Published As

Publication number Publication date
CA2336412C (en) 2007-11-27
US6489331B1 (en) 2002-12-03
ES2284256T3 (es) 2007-11-01
DE69935718D1 (de) 2007-05-16
EP1092435A4 (de) 2004-03-17
EP1092435B1 (de) 2007-04-04
WO2000001388A1 (en) 2000-01-13
AU4396899A (en) 2000-01-24
DE69935718T2 (de) 2007-12-27
CA2336412A1 (en) 2000-01-13
EP1092435A1 (de) 2001-04-18

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties