ATE358484T1 - Antidiabetische medikamente - Google Patents
Antidiabetische medikamenteInfo
- Publication number
- ATE358484T1 ATE358484T1 AT99926903T AT99926903T ATE358484T1 AT E358484 T1 ATE358484 T1 AT E358484T1 AT 99926903 T AT99926903 T AT 99926903T AT 99926903 T AT99926903 T AT 99926903T AT E358484 T1 ATE358484 T1 AT E358484T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- group
- unsubstituted
- hydrogen atom
- lower alkyl
- Prior art date
Links
- 229940127003 anti-diabetic drug Drugs 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18770598 | 1998-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE358484T1 true ATE358484T1 (de) | 2007-04-15 |
Family
ID=16210732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926903T ATE358484T1 (de) | 1998-07-02 | 1999-07-02 | Antidiabetische medikamente |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6489331B1 (de) |
| EP (1) | EP1092435B1 (de) |
| AT (1) | ATE358484T1 (de) |
| AU (1) | AU4396899A (de) |
| CA (1) | CA2336412C (de) |
| DE (1) | DE69935718T2 (de) |
| ES (1) | ES2284256T3 (de) |
| WO (1) | WO2000001388A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ527917A (en) | 1999-11-12 | 2005-03-24 | Biogen Inc | Polycycoalkylpurines as adenosine receptor antagonists |
| IL149486A0 (en) | 1999-11-12 | 2002-11-10 | Biogen Inc | Purine derivatives and pharmaceutical compositions containing the same |
| DE60018216T2 (de) | 1999-12-24 | 2006-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Kondensierte purinderivate |
| UA75625C2 (en) * | 2000-12-01 | 2006-05-15 | Biogen Inc | Condensed purine derivatives as a1 adenosine receptor antagonists |
| ES2287466T3 (es) | 2002-03-22 | 2007-12-16 | Janssen Pharmaceutica N.V. | Derivados de 2-quinolinona y quinazolina de bencilimidazolil sustituidas como inhibidores de la farnesil transferasa. |
| WO2003097064A1 (en) * | 2002-05-17 | 2003-11-27 | Kyowa Hakko Kogyo Co., Ltd. | Therapeutic agent for diabetes |
| JPWO2003097862A1 (ja) * | 2002-05-17 | 2005-09-15 | 協和醗酵工業株式会社 | 抗糖尿病作用を有する物質の探索方法 |
| AU2003252697A1 (en) * | 2002-07-26 | 2004-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Cell differentiation inductor |
| JP4571497B2 (ja) | 2002-09-19 | 2010-10-27 | 杏林製薬株式会社 | アミノアルコール誘導体とその付加塩及び免疫抑制剤 |
| CA2523763A1 (en) * | 2003-04-25 | 2004-11-11 | Kyowa Hakko Kogyo Co., Ltd. | Fused pyrimidine derivative |
| CN101905023B (zh) * | 2004-07-16 | 2012-07-11 | 杏林制药株式会社 | 有效的医药使用方法及与副作用发生的防御相关的方法 |
| PL1806338T3 (pl) * | 2004-10-12 | 2016-07-29 | Kyorin Seiyaku Kk | Sposób wytwarzania chlorowodorku 2-amino-2-[2-[4-(3-benzyloksyfenylotio)-2-chlorofenyio]etylo]-1,3-propanodioiu i jego hydratów oraz produkty pośrednie w ich wytwarzaniu |
| SI1932522T1 (sl) * | 2005-10-07 | 2012-08-31 | Kyorin Seiyaku Kk | Terapevtsko sredstvo za jetrno bolezen, ki vsebuje 2-amino-1,3- propandiolni derivat kot aktivno sestavino |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| AR061626A1 (es) * | 2006-06-23 | 2008-09-10 | Incyte Corp | Derivados de purinona como agonistas de hm74a |
| US7511050B2 (en) | 2006-06-23 | 2009-03-31 | Incyte Corporation | Purinone derivatives as HM74A agonists |
| CN101479273B (zh) * | 2006-06-23 | 2011-11-30 | 英赛特股份有限公司 | 作为hm74a激动剂的嘌呤酮衍生物 |
| CA2659599C (en) * | 2006-08-08 | 2014-06-17 | Kyorin Pharmaceutical Co., Ltd. | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
| RU2430925C2 (ru) * | 2006-08-08 | 2011-10-10 | Киорин Фармасьютикал Ко., Лтд. | Производное аминофосфата и модулятор рецептора s1p, содержащий его в качестве активного ингредиента |
| JP4337898B2 (ja) * | 2007-03-29 | 2009-09-30 | セイコーエプソン株式会社 | 半導体装置 |
| JP5452237B2 (ja) | 2008-02-07 | 2014-03-26 | 杏林製薬株式会社 | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
| EP2145621A1 (de) * | 2008-07-16 | 2010-01-20 | Stephan Lück | Verhinderung der Dehydrierung und Reduzierung der gluconeogenetischen Verluste von Aminosäuren durch Propan-1,2,3-Triol |
| WO2012136121A1 (zh) * | 2011-04-02 | 2012-10-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 氨基苯丙醇类化合物及其用于制备免疫抑制剂的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2028235C (en) | 1989-10-20 | 1997-01-21 | Fumio Suzuki | Condensed purine derivatives |
| GB9015914D0 (en) * | 1990-07-19 | 1990-09-05 | Wellcome Found | Heterocyclic compounds |
| JP3204880B2 (ja) | 1995-07-25 | 2001-09-04 | 株式会社バーテックススタンダード | デジタルフィルタ |
| EP0884318A4 (de) | 1996-10-07 | 2002-10-23 | Kyowa Hakko Kogyo Kk | Kondensierte purinderivate |
| JP4354016B2 (ja) | 1996-11-29 | 2009-10-28 | 株式会社メディサイエンスプラニング | 新規プリン誘導体およびこれを含む医薬組成物 |
-
1999
- 1999-07-02 AU AU43968/99A patent/AU4396899A/en not_active Abandoned
- 1999-07-02 DE DE69935718T patent/DE69935718T2/de not_active Expired - Fee Related
- 1999-07-02 EP EP99926903A patent/EP1092435B1/de not_active Expired - Lifetime
- 1999-07-02 ES ES99926903T patent/ES2284256T3/es not_active Expired - Lifetime
- 1999-07-02 AT AT99926903T patent/ATE358484T1/de not_active IP Right Cessation
- 1999-07-02 CA CA002336412A patent/CA2336412C/en not_active Expired - Fee Related
- 1999-07-02 US US09/719,570 patent/US6489331B1/en not_active Expired - Fee Related
- 1999-07-02 WO PCT/JP1999/003583 patent/WO2000001388A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2336412C (en) | 2007-11-27 |
| US6489331B1 (en) | 2002-12-03 |
| EP1092435B1 (de) | 2007-04-04 |
| CA2336412A1 (en) | 2000-01-13 |
| ES2284256T3 (es) | 2007-11-01 |
| AU4396899A (en) | 2000-01-24 |
| DE69935718T2 (de) | 2007-12-27 |
| EP1092435A1 (de) | 2001-04-18 |
| DE69935718D1 (de) | 2007-05-16 |
| EP1092435A4 (de) | 2004-03-17 |
| WO2000001388A1 (en) | 2000-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |