ATE358484T1 - Antidiabetische medikamente - Google Patents

Antidiabetische medikamente

Info

Publication number
ATE358484T1
ATE358484T1 AT99926903T AT99926903T ATE358484T1 AT E358484 T1 ATE358484 T1 AT E358484T1 AT 99926903 T AT99926903 T AT 99926903T AT 99926903 T AT99926903 T AT 99926903T AT E358484 T1 ATE358484 T1 AT E358484T1
Authority
AT
Austria
Prior art keywords
substituted
group
unsubstituted
hydrogen atom
lower alkyl
Prior art date
Application number
AT99926903T
Other languages
English (en)
Inventor
Junichi Shimada
Yoshihisa Ohta
Kotaro Takasaki
Miho Suda
Hideaki Kusaka
Hiroshi Yano
Satoshi Nakanishi
Yuzuru Matsuda
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE358484T1 publication Critical patent/ATE358484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT99926903T 1998-07-02 1999-07-02 Antidiabetische medikamente ATE358484T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18770598 1998-07-02

Publications (1)

Publication Number Publication Date
ATE358484T1 true ATE358484T1 (de) 2007-04-15

Family

ID=16210732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99926903T ATE358484T1 (de) 1998-07-02 1999-07-02 Antidiabetische medikamente

Country Status (8)

Country Link
US (1) US6489331B1 (de)
EP (1) EP1092435B1 (de)
AT (1) ATE358484T1 (de)
AU (1) AU4396899A (de)
CA (1) CA2336412C (de)
DE (1) DE69935718T2 (de)
ES (1) ES2284256T3 (de)
WO (1) WO2000001388A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200201260T2 (tr) 1999-11-12 2002-09-23 Biogen, Inc. Adenosin reseptör antagonistleri olarak polisikloalkilpurinler.
GEP20043267B (en) 1999-11-12 2004-06-25 Biogen Inc Us Adenosine Receptor Antagonists, Methods of Making and Using the Same
WO2001047931A1 (en) * 1999-12-24 2001-07-05 Kyowa Hakko Kogyo Co., Ltd. Fused purine derivatives
AU2002219977B2 (en) 2000-12-01 2008-01-24 Biogen Idec Ma Inc. Condensed purine derivatives as A1 adenosine receptor antagonists
AU2003223970B2 (en) 2002-03-22 2008-03-06 Janssen Pharmaceutica N.V. Benzylimidazolyl substituted 2-quinoline and quinazoline derivatives for use as farnesyl transferase inhibitors
KR20040111636A (ko) * 2002-05-17 2004-12-31 교와 핫꼬 고교 가부시끼가이샤 항당뇨병 작용을 갖는 물질의 탐색방법
WO2003097064A1 (en) * 2002-05-17 2003-11-27 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for diabetes
AU2003252697A1 (en) * 2002-07-26 2004-02-16 Kyowa Hakko Kogyo Co., Ltd. Cell differentiation inductor
AU2003264430B2 (en) 2002-09-19 2009-03-19 Kyorin Pharmaceutical Co., Ltd. Amino alcohol derivative, addition salt thereof, and immunosuppressant
WO2004096812A1 (ja) * 2003-04-25 2004-11-11 Kyowa Hakko Kogyo Co., Ltd. 縮合ピリミジン誘導体
PL1772145T3 (pl) * 2004-07-16 2011-08-31 Kyorin Seiyaku Kk Sposób skutecznego stosowania leku i sposób dotyczący zapobiegania efektom ubocznym
PL2511262T3 (pl) * 2004-10-12 2017-08-31 Kyorin Pharmaceutical Co., Ltd. Sposób wytwarzania chlorowodorku 2-amino-2-[2-[4-(3-benzyloksyfenylotio)-2-chlorofenylo]etylo]-1,3-propanodiolu
RU2421214C2 (ru) * 2005-10-07 2011-06-20 Киорин Фармасьютикал Ко., Лтд. Терапевтическое средство для лечения гепатита и способ лечения гепатита
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
EP2049544B9 (de) * 2006-06-23 2011-07-20 Incyte Corporation Purinonderivate als hm74a-agonisten
KR20090025261A (ko) 2006-06-23 2009-03-10 인사이트 코포레이션 Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체
BRPI0713561A2 (pt) * 2006-06-23 2012-03-13 Incyte Corporation composto ou um sal ou pró-droga farmaceuticamente aceitável do mesmo, composição, e, métodos de modulação do receptor e de tratamento de uma doença
DK2058317T3 (da) * 2006-08-08 2014-01-06 Kyorin Seiyaku Kk Aminophosphorsyreesterderivat og S1P receptormodulator indeholdende samme som aktiv ingrediens
WO2008018447A1 (en) * 2006-08-08 2008-02-14 Kyorin Pharmaceutical Co., Ltd. Aminoalcohol derivative and immunosuppressant containing the same as active ingredient
JP4337898B2 (ja) * 2007-03-29 2009-09-30 セイコーエプソン株式会社 半導体装置
WO2009099174A1 (ja) 2008-02-07 2009-08-13 Kyorin Pharmaceutical Co., Ltd. アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤
EP2145621A1 (de) * 2008-07-16 2010-01-20 Stephan Lück Verhinderung der Dehydrierung und Reduzierung der gluconeogenetischen Verluste von Aminosäuren durch Propan-1,2,3-Triol
WO2012136121A1 (zh) * 2011-04-02 2012-10-11 中国人民解放军军事医学科学院毒物药物研究所 氨基苯丙醇类化合物及其用于制备免疫抑制剂的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2152207T3 (es) * 1989-10-20 2001-02-01 Kyowa Hakko Kogyo Kk Derivados condensados de la purina.
GB9015914D0 (en) * 1990-07-19 1990-09-05 Wellcome Found Heterocyclic compounds
JP3204880B2 (ja) 1995-07-25 2001-09-04 株式会社バーテックススタンダード デジタルフィルタ
EP0884318A4 (de) * 1996-10-07 2002-10-23 Kyowa Hakko Kogyo Kk Kondensierte purinderivate
JP4354016B2 (ja) 1996-11-29 2009-10-28 株式会社メディサイエンスプラニング 新規プリン誘導体およびこれを含む医薬組成物

Also Published As

Publication number Publication date
ES2284256T3 (es) 2007-11-01
DE69935718D1 (de) 2007-05-16
EP1092435A1 (de) 2001-04-18
WO2000001388A1 (en) 2000-01-13
AU4396899A (en) 2000-01-24
US6489331B1 (en) 2002-12-03
EP1092435A4 (de) 2004-03-17
CA2336412C (en) 2007-11-27
CA2336412A1 (en) 2000-01-13
EP1092435B1 (de) 2007-04-04
DE69935718T2 (de) 2007-12-27

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties