KR880005948A - 약물의 경피 투여구 - Google Patents
약물의 경피 투여구 Download PDFInfo
- Publication number
- KR880005948A KR880005948A KR870013295A KR870013295A KR880005948A KR 880005948 A KR880005948 A KR 880005948A KR 870013295 A KR870013295 A KR 870013295A KR 870013295 A KR870013295 A KR 870013295A KR 880005948 A KR880005948 A KR 880005948A
- Authority
- KR
- South Korea
- Prior art keywords
- drug
- type
- oscillator
- ultrasonic
- percutaneous administration
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title claims abstract description 13
- 239000003814 drug Substances 0.000 title claims abstract description 13
- 230000010355 oscillation Effects 0.000 claims 3
- 238000010521 absorption reaction Methods 0.000 abstract 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 10
- 102000004877 Insulin Human genes 0.000 description 5
- 108090001061 Insulin Proteins 0.000 description 5
- 229940125396 insulin Drugs 0.000 description 5
- 238000002604 ultrasonography Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 238000001647 drug administration Methods 0.000 description 2
- 239000012790 adhesive layer Substances 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
- A61H23/0245—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with ultrasonic transducers, e.g. piezoelectric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
- A61H2201/105—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy with means for delivering media, e.g. drugs or cosmetics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Rehabilitation Therapy (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Coating Apparatus (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 본 발명의 정지형 약물 투여구의 단면도.
제 2 도는 동 휴대형 약물 투여구의 단면도.
제 3 도는 동 상용형 약물 투여구의 단면도.
* 도면의 주요부분에 대한 부호의 설명
1 : 초음파발진기 2 : 초음파 발진소자
3 : 약물층 4 : 전지
5 : 접착층 6 : 보호필름
7 : 단자 8 : 초음과 진동 집파구
9 : 스폰지형상 완충재 a : 물에만 침지했을 경우
b : 초음파(5000∼7000Pa)부여로 물에 침지했을 경우
c : 초음파(3000~ 5000Pa)부여로 물에 침지했을 경우
d : 인슐린 20U/m1에 침지했을 경우
e : 초음파(3000∼5000Pa) 부여로 인슐린 20U/m1용액에 침지했을 경우
f : 초음파(5000∼7000Pa) 부여로 인슐린 20U/ml 용액에 침지했을 경우
A : 인슐린 겔 초음파(1750Pa)를 부여했을 경우
B : 인슐린 겔/초음파를 부여하지 않았을 경우
Claims (3)
- 초음파 발진소자에 근접하여 약물층을 설치하여 이루어진 것을 특징으로 하는 약물의 경피 투여구.
- 제 1 항에 있어서, 통상 용기에 초음파 발진기 및 초음파 발진소자를 내장하고, 그 선단에 약물층을 설치하여 이루어진 것을 특징으로 하는 약물의 경피 투여구.
- 제 1 항에 있어서, 편평형 용기에 IC초음파 발진기 및 초음파 발진소자를 내장하고, 그 하면에 약물층을 설치하여 이루어진 것을 특징으로 하는 약물의 경피 투여구.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61-282703 | 1986-11-26 | ||
JP61282703A JPS63135179A (ja) | 1986-11-26 | 1986-11-26 | 薬物の経皮投与具 |
JP282703 | 1986-11-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880005948A true KR880005948A (ko) | 1988-07-21 |
KR900004318B1 KR900004318B1 (ko) | 1990-06-22 |
Family
ID=17655952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870013295A KR900004318B1 (ko) | 1986-11-26 | 1987-11-25 | 약물의 경피 투여구 |
Country Status (8)
Country | Link |
---|---|
US (3) | US4821740A (ko) |
EP (2) | EP0495531B1 (ko) |
JP (1) | JPS63135179A (ko) |
KR (1) | KR900004318B1 (ko) |
AT (2) | ATE88100T1 (ko) |
DE (2) | DE3751121T2 (ko) |
ES (1) | ES2039409T3 (ko) |
GR (1) | GR3008251T3 (ko) |
Families Citing this family (640)
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SU614788A1 (ru) * | 1975-12-25 | 1978-07-15 | Центральный Ордена Трудового Красного Знамени Научно-Исследовательский Институт Травматологии И Ортопедии Имени Н.Н.Приорова | Способ проведени гемостаза |
CA1083040A (en) * | 1976-02-09 | 1980-08-05 | Mostafa Fahim | Topical application of medication by ultrasound with coupling agent |
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-
1986
- 1986-11-26 JP JP61282703A patent/JPS63135179A/ja active Granted
-
1987
- 1987-11-13 US US07/120,555 patent/US4821740A/en not_active Expired - Lifetime
- 1987-11-23 AT AT87117242T patent/ATE88100T1/de not_active IP Right Cessation
- 1987-11-23 EP EP92104802A patent/EP0495531B1/en not_active Expired - Lifetime
- 1987-11-23 ES ES198787117242T patent/ES2039409T3/es not_active Expired - Lifetime
- 1987-11-23 AT AT92104802T patent/ATE119021T1/de not_active IP Right Cessation
- 1987-11-23 DE DE3751121T patent/DE3751121T2/de not_active Expired - Fee Related
- 1987-11-23 EP EP87117242A patent/EP0278074B1/en not_active Expired - Lifetime
- 1987-11-23 DE DE8787117242T patent/DE3785442T2/de not_active Expired - Fee Related
- 1987-11-25 KR KR1019870013295A patent/KR900004318B1/ko not_active IP Right Cessation
-
1989
- 1989-03-28 US US07/329,913 patent/US4953565A/en not_active Expired - Lifetime
- 1989-03-28 US US07/329,914 patent/US5007438A/en not_active Expired - Lifetime
-
1993
- 1993-06-24 GR GR920403203T patent/GR3008251T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0363913B2 (ko) | 1991-10-03 |
EP0278074A2 (en) | 1988-08-17 |
EP0278074B1 (en) | 1993-04-14 |
KR900004318B1 (ko) | 1990-06-22 |
ES2039409T3 (es) | 1993-10-01 |
US4821740A (en) | 1989-04-18 |
DE3785442T2 (de) | 1993-09-16 |
EP0278074A3 (en) | 1989-07-26 |
EP0495531A1 (en) | 1992-07-22 |
GR3008251T3 (ko) | 1993-09-30 |
DE3751121T2 (de) | 1995-06-22 |
DE3785442D1 (de) | 1993-05-19 |
US4953565A (en) | 1990-09-04 |
ATE119021T1 (de) | 1995-03-15 |
ATE88100T1 (de) | 1993-04-15 |
US5007438A (en) | 1991-04-16 |
EP0495531B1 (en) | 1995-03-01 |
DE3751121D1 (de) | 1995-04-06 |
JPS63135179A (ja) | 1988-06-07 |
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