KR880002354B1 - 1,2-디하이드로-6-(저급알킬)-2-옥소-5-(피리디닐)니코티노니트릴류 및 니코틴아미드류의 제조방법 - Google Patents

1,2-디하이드로-6-(저급알킬)-2-옥소-5-(피리디닐)니코티노니트릴류 및 니코틴아미드류의 제조방법 Download PDF

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Publication number
KR880002354B1
KR880002354B1 KR1019830002192A KR830002192A KR880002354B1 KR 880002354 B1 KR880002354 B1 KR 880002354B1 KR 1019830002192 A KR1019830002192 A KR 1019830002192A KR 830002192 A KR830002192 A KR 830002192A KR 880002354 B1 KR880002354 B1 KR 880002354B1
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South Korea
Prior art keywords
pyridinyl
dihydro
oxo
methyl
ethoxy
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Expired
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KR1019830002192A
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English (en)
Korean (ko)
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KR850001191A (ko
Inventor
올라프 젤롯트 칼
싱 발데브
Original Assignee
스터어링 드럭그 인코포레이팃드
원본미기재
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Filing date
Publication date
Priority claimed from US06/381,162 external-priority patent/US4417054A/en
Priority claimed from US06/381,062 external-priority patent/US4413127A/en
Priority claimed from US06/471,961 external-priority patent/US4469871A/en
Application filed by 스터어링 드럭그 인코포레이팃드, 원본미기재 filed Critical 스터어링 드럭그 인코포레이팃드
Publication of KR850001191A publication Critical patent/KR850001191A/ko
Application granted granted Critical
Publication of KR880002354B1 publication Critical patent/KR880002354B1/ko
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019830002192A 1982-05-24 1983-05-18 1,2-디하이드로-6-(저급알킬)-2-옥소-5-(피리디닐)니코티노니트릴류 및 니코틴아미드류의 제조방법 Expired KR880002354B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US381062 1982-05-24
US06/381,162 US4417054A (en) 1982-05-24 1982-05-24 2-(Lower-alkoxy)-1-(pyridinyl)ethenyl lower-alkyl ketones
US381.162 1982-05-24
US06/381,062 US4413127A (en) 1982-05-24 1982-05-24 Preparation of 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(pyridinyl)nicotinonitriles
US381.062 1982-05-24
US381162 1982-05-24
US06/471,961 US4469871A (en) 1982-05-24 1983-03-03 Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones
US471961 1983-03-03
US471.961 1983-03-03

Publications (2)

Publication Number Publication Date
KR850001191A KR850001191A (ko) 1985-03-16
KR880002354B1 true KR880002354B1 (ko) 1988-10-29

Family

ID=27409519

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019830002192A Expired KR880002354B1 (ko) 1982-05-24 1983-05-18 1,2-디하이드로-6-(저급알킬)-2-옥소-5-(피리디닐)니코티노니트릴류 및 니코틴아미드류의 제조방법
KR1019880012161D Expired KR890001543B1 (ko) 1982-05-24 1983-05-18 2-(저급알콕시)-1-(피리디닐)에테닐 저급알킬케톤 및 그 제조방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019880012161D Expired KR890001543B1 (ko) 1982-05-24 1983-05-18 2-(저급알콕시)-1-(피리디닐)에테닐 저급알킬케톤 및 그 제조방법

Country Status (14)

Country Link
EP (1) EP0095152B1 (https=)
KR (2) KR880002354B1 (https=)
AU (1) AU559149B2 (https=)
DE (1) DE3367091D1 (https=)
DK (1) DK157488C (https=)
ES (2) ES522506A0 (https=)
FI (1) FI80021C (https=)
GR (1) GR78573B (https=)
HK (1) HK79591A (https=)
IE (1) IE55135B1 (https=)
IL (1) IL68671A (https=)
NO (1) NO163008C (https=)
NZ (1) NZ204175A (https=)
PT (1) PT76710B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4976774A (en) * 1984-07-20 1990-12-11 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations 1-(4'-pyridyl)-4-pyridone, its derivatives and herbicidal use thereof
CN111377858B (zh) * 2018-12-30 2023-04-07 鲁南制药集团股份有限公司 一种米力农的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824121A (en) * 1954-11-04 1958-02-18 Kay Fries Chemicals Inc Process for preparation of oxy alkylidene compounds
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones
DE2909287A1 (de) * 1979-03-09 1980-09-18 Bayer Ag 3-substituierte pyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
US4223149A (en) * 1979-07-26 1980-09-16 Sterling Drug Inc. Process for producing 3-cyano-5-(pyridinyl)-2(1H)-pyridinones
US4313951A (en) * 1979-11-26 1982-02-02 Sterling Drug Inc. 3-Substituted-6-(lower-alkyl)-5-(pyridinyl)-2(1H)-pyridinones, their cardiotonic use and intermediates therefor
US4310670A (en) * 1980-02-26 1982-01-12 Sterling Drug Inc. Low-temperature, aqueous conversion of 4-picoline derivative to 5-cyano-[3,4'-bipyridin]-6(1H)-one
US4276293A (en) * 1980-03-28 1981-06-30 Sterling Drug Inc. Compositions and their preparation
US4347363A (en) * 1981-09-17 1982-08-31 Sterling Drug Inc. Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles

Also Published As

Publication number Publication date
FI80021C (fi) 1990-04-10
DK157488C (da) 1990-06-11
DK224283A (da) 1983-11-25
DK224283D0 (da) 1983-05-19
IL68671A0 (en) 1983-09-30
ES8601132A1 (es) 1985-10-16
AU559149B2 (en) 1987-02-26
DK157488B (da) 1990-01-15
EP0095152B1 (en) 1986-10-22
FI831730L (fi) 1983-11-25
KR850001191A (ko) 1985-03-16
NO163008B (no) 1989-12-11
HK79591A (en) 1991-10-18
ES8506693A1 (es) 1985-08-01
ES522506A0 (es) 1985-08-01
FI831730A0 (fi) 1983-05-17
NO163008C (no) 1990-03-21
AU1442383A (en) 1983-12-01
EP0095152A1 (en) 1983-11-30
FI80021B (fi) 1989-12-29
PT76710B (en) 1985-12-27
NO831638L (no) 1983-11-25
PT76710A (en) 1983-06-01
IE55135B1 (en) 1990-06-06
GR78573B (https=) 1984-09-27
IE831155L (en) 1983-11-24
ES535990A0 (es) 1985-10-16
DE3367091D1 (en) 1986-11-27
KR890001543B1 (ko) 1989-05-08
NZ204175A (en) 1985-12-13
IL68671A (en) 1986-07-31

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