PT76710B - Process for the preparation of nicotinonitriles and nicotinamides and intermediates used therein - Google Patents
Process for the preparation of nicotinonitriles and nicotinamides and intermediates used thereinInfo
- Publication number
- PT76710B PT76710B PT76710A PT7671083A PT76710B PT 76710 B PT76710 B PT 76710B PT 76710 A PT76710 A PT 76710A PT 7671083 A PT7671083 A PT 7671083A PT 76710 B PT76710 B PT 76710B
- Authority
- PT
- Portugal
- Prior art keywords
- nicotinonitriles
- nicotinamides
- preparation
- intermediates used
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/381,062 US4413127A (en) | 1982-05-24 | 1982-05-24 | Preparation of 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(pyridinyl)nicotinonitriles |
| US06/381,162 US4417054A (en) | 1982-05-24 | 1982-05-24 | 2-(Lower-alkoxy)-1-(pyridinyl)ethenyl lower-alkyl ketones |
| US06/471,961 US4469871A (en) | 1982-05-24 | 1983-03-03 | Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT76710A PT76710A (en) | 1983-06-01 |
| PT76710B true PT76710B (en) | 1985-12-27 |
Family
ID=27409519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT76710A PT76710B (en) | 1982-05-24 | 1983-05-17 | Process for the preparation of nicotinonitriles and nicotinamides and intermediates used therein |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0095152B1 (en) |
| KR (2) | KR880002354B1 (en) |
| AU (1) | AU559149B2 (en) |
| DE (1) | DE3367091D1 (en) |
| DK (1) | DK157488C (en) |
| ES (2) | ES8506693A1 (en) |
| FI (1) | FI80021C (en) |
| GR (1) | GR78573B (en) |
| HK (1) | HK79591A (en) |
| IE (1) | IE55135B1 (en) |
| IL (1) | IL68671A (en) |
| NO (1) | NO163008C (en) |
| NZ (1) | NZ204175A (en) |
| PT (1) | PT76710B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4976774A (en) * | 1984-07-20 | 1990-12-11 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | 1-(4'-pyridyl)-4-pyridone, its derivatives and herbicidal use thereof |
| CN111377858B (en) * | 2018-12-30 | 2023-04-07 | 鲁南制药集团股份有限公司 | Preparation method of milrinone |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2824121A (en) * | 1954-11-04 | 1958-02-18 | Kay Fries Chemicals Inc | Process for preparation of oxy alkylidene compounds |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
| DE2909287A1 (en) * | 1979-03-09 | 1980-09-18 | Bayer Ag | 3-SUBSTITUTED PYRIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES |
| US4223149A (en) * | 1979-07-26 | 1980-09-16 | Sterling Drug Inc. | Process for producing 3-cyano-5-(pyridinyl)-2(1H)-pyridinones |
| US4313951A (en) * | 1979-11-26 | 1982-02-02 | Sterling Drug Inc. | 3-Substituted-6-(lower-alkyl)-5-(pyridinyl)-2(1H)-pyridinones, their cardiotonic use and intermediates therefor |
| US4310670A (en) * | 1980-02-26 | 1982-01-12 | Sterling Drug Inc. | Low-temperature, aqueous conversion of 4-picoline derivative to 5-cyano-[3,4'-bipyridin]-6(1H)-one |
| US4276293A (en) * | 1980-03-28 | 1981-06-30 | Sterling Drug Inc. | Compositions and their preparation |
| US4347363A (en) * | 1981-09-17 | 1982-08-31 | Sterling Drug Inc. | Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles |
-
1983
- 1983-05-09 NO NO831638A patent/NO163008C/en not_active IP Right Cessation
- 1983-05-09 NZ NZ204175A patent/NZ204175A/en unknown
- 1983-05-10 AU AU14423/83A patent/AU559149B2/en not_active Expired
- 1983-05-12 IL IL68671A patent/IL68671A/en not_active IP Right Cessation
- 1983-05-17 PT PT76710A patent/PT76710B/en unknown
- 1983-05-17 IE IE1155/83A patent/IE55135B1/en not_active IP Right Cessation
- 1983-05-17 FI FI831730A patent/FI80021C/en not_active IP Right Cessation
- 1983-05-18 GR GR71382A patent/GR78573B/el unknown
- 1983-05-18 KR KR1019830002192A patent/KR880002354B1/en not_active IP Right Cessation
- 1983-05-18 KR KR1019880012161D patent/KR890001543B1/en active
- 1983-05-18 ES ES522506A patent/ES8506693A1/en not_active Expired
- 1983-05-19 DK DK224283A patent/DK157488C/en not_active IP Right Cessation
- 1983-05-19 EP EP83104984A patent/EP0095152B1/en not_active Expired
- 1983-05-19 DE DE8383104984T patent/DE3367091D1/en not_active Expired
-
1984
- 1984-09-17 ES ES535990A patent/ES8601132A1/en not_active Expired
-
1991
- 1991-10-10 HK HK795/91A patent/HK79591A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES522506A0 (en) | 1985-08-01 |
| GR78573B (en) | 1984-09-27 |
| NO831638L (en) | 1983-11-25 |
| IE831155L (en) | 1983-11-24 |
| FI80021B (en) | 1989-12-29 |
| DK224283D0 (en) | 1983-05-19 |
| ES8506693A1 (en) | 1985-08-01 |
| DE3367091D1 (en) | 1986-11-27 |
| ES535990A0 (en) | 1985-10-16 |
| FI831730A0 (en) | 1983-05-17 |
| EP0095152B1 (en) | 1986-10-22 |
| AU559149B2 (en) | 1987-02-26 |
| PT76710A (en) | 1983-06-01 |
| HK79591A (en) | 1991-10-18 |
| AU1442383A (en) | 1983-12-01 |
| NZ204175A (en) | 1985-12-13 |
| ES8601132A1 (en) | 1985-10-16 |
| NO163008C (en) | 1990-03-21 |
| IE55135B1 (en) | 1990-06-06 |
| DK224283A (en) | 1983-11-25 |
| DK157488B (en) | 1990-01-15 |
| NO163008B (en) | 1989-12-11 |
| IL68671A0 (en) | 1983-09-30 |
| IL68671A (en) | 1986-07-31 |
| FI80021C (en) | 1990-04-10 |
| EP0095152A1 (en) | 1983-11-30 |
| KR890001543B1 (en) | 1989-05-08 |
| DK157488C (en) | 1990-06-11 |
| KR850001191A (en) | 1985-03-16 |
| FI831730L (en) | 1983-11-25 |
| KR880002354B1 (en) | 1988-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC3A | Transfer or assignment |
Free format text: 980513 SANOFI PHARMACEUTICALS, INC. US |
|
| PD3A | Change of proprietorship | ||
| PD3A | Change of proprietorship |
Owner name: SANOFI-SYNTHELABO INC. Effective date: 20000209 |