KR860002525A - 거 담 약 - Google Patents

거 담 약 Download PDF

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Publication number
KR860002525A
KR860002525A KR1019850006606A KR850006606A KR860002525A KR 860002525 A KR860002525 A KR 860002525A KR 1019850006606 A KR1019850006606 A KR 1019850006606A KR 850006606 A KR850006606 A KR 850006606A KR 860002525 A KR860002525 A KR 860002525A
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KR
South Korea
Prior art keywords
expectorant
giant
pills
wall
directly
Prior art date
Application number
KR1019850006606A
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English (en)
Other versions
KR880001234B1 (ko
Inventor
사다노리 오가사와라
Original Assignee
곤도오 야스누리
간도오이시 세이야꾸 가부시기 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 곤도오 야스누리, 간도오이시 세이야꾸 가부시기 가이샤 filed Critical 곤도오 야스누리
Publication of KR860002525A publication Critical patent/KR860002525A/ko
Application granted granted Critical
Publication of KR880001234B1 publication Critical patent/KR880001234B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

거담약
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1,2도는 N-아세틸뉴라민산의 선모세포의 회전운동에 대한 작용을 나타내는 그라프, 제3,4도는, 각각 테르부탈린 및 아세틸콜린의 선모세포의 회전운동에 대한 작용을 나타내는 그래프.

Claims (3)

  1. 기도의 섬모세포에 직접 작용할 수 있고 담의 유동성에 직접 작용할 수 있으며, 다음의 일반식으로 나타나는 거담약:
    단, n=1 일때 z는 수소, 리튬, 칼륨, 나트륨, 암모늄, 유기암모늄 또는 유기아민이고, n=2 일때 z는 칼슘, 바륨 또는 마그네슘을 나타낸다.
  2. 제1항에 있어서, 에러졸 흡입으로 투약되는 것을 특징으로 하는 거담약.
  3. 제2항에 있어서, 거담약의 투여량이 0.5~5㎎/희 인 거담약.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850006606A 1984-09-11 1985-09-10 N-아세틸뉴라민산염의 제조 방법 KR880001234B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59-189950 1984-09-11
JP59189950A JPS6168418A (ja) 1984-09-11 1984-09-11 去痰薬

Publications (2)

Publication Number Publication Date
KR860002525A true KR860002525A (ko) 1986-04-26
KR880001234B1 KR880001234B1 (ko) 1988-07-12

Family

ID=16249907

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850006606A KR880001234B1 (ko) 1984-09-11 1985-09-10 N-아세틸뉴라민산염의 제조 방법

Country Status (14)

Country Link
US (1) US4698332A (ko)
EP (2) EP0429430B1 (ko)
JP (1) JPS6168418A (ko)
KR (1) KR880001234B1 (ko)
CN (1) CN85108388B (ko)
AT (2) ATE111738T1 (ko)
AU (1) AU582584B2 (ko)
CA (1) CA1246452A (ko)
DE (2) DE3587928T2 (ko)
DK (1) DK165046C (ko)
ES (1) ES8606323A1 (ko)
FI (1) FI83963C (ko)
HU (2) HU198733B (ko)
ZA (1) ZA856905B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61289037A (ja) * 1985-06-14 1986-12-19 Mect Corp 新規去痰薬
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
JPH0530649Y2 (ko) * 1986-08-28 1993-08-05
JP2573594B2 (ja) * 1987-03-06 1997-01-22 メクト株式会社 Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法
US5843445A (en) * 1987-06-24 1998-12-01 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
JP2517293B2 (ja) * 1987-06-25 1996-07-24 メクト株式会社 細胞、組織修復剤
US5393742A (en) * 1990-08-30 1995-02-28 Mect Corporation Preparation for treating renal disease
US5514665A (en) * 1993-12-30 1996-05-07 University Of British Columbia Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
AUPQ275799A0 (en) * 1999-09-10 1999-10-07 Luminis Pty Limited Recombinant bacterium expressing an oligosaccharide receptor mimic
JP4005115B1 (ja) 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US9241896B2 (en) * 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
UA110325C2 (en) * 2009-07-03 2015-12-25 Australian Biomedical Company Pty Ltd Medicinal carbohydrates for treating respiratory conditions
KR20140003380A (ko) 2010-07-13 2014-01-09 울트라제닉스 파마수티컬 인코포레이티드 시알산 결함 치료용 방법들 및 제형들
MX347541B (es) 2011-10-24 2017-04-28 Ultragenyx Pharmaceutical Inc Analogos de acido sialico.
US11246878B2 (en) * 2013-03-15 2022-02-15 B&H Biotechnologies, Llc Compositions and products for infectious or inflammatory diseases or conditions
WO2014151526A1 (en) 2013-03-15 2014-09-25 Huiru Wang Biological therapeutics for infection-relating disorders or conditions
ES2710330T3 (es) 2014-07-30 2019-04-24 Kyowa Hakko Bio Co Ltd Cristal de anhidrato de N-acetilneuraminato de metal alcalino, y método para producir el mismo
JP6671305B2 (ja) 2015-01-28 2020-03-25 協和発酵バイオ株式会社 Ｎ−アセチルノイラミン酸アンモニウム塩・無水和物の結晶及びその製造方法
WO2017048817A1 (en) 2015-09-14 2017-03-23 Ultragenyx Pharmaceutical Inc. Crystal forms of sialic acid or salt or solvate thereof
CN109771316B (zh) * 2018-12-29 2022-02-25 中国科学院合肥物质科学研究院 一种提高n-乙酰神经氨酸水溶液稳定性的方法及其应用
CN110606864B (zh) * 2019-10-08 2023-10-10 中国科学院合肥物质科学研究院 一种n-乙酰神经氨酸钙盐晶体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Also Published As

Publication number Publication date
EP0429430A3 (en) 1991-10-23
DE3587587D1 (de) 1993-10-21
FI853456L (fi) 1986-03-12
EP0429430A2 (en) 1991-05-29
EP0177783A2 (en) 1986-04-16
EP0177783A3 (en) 1989-02-22
JPS6168418A (ja) 1986-04-08
EP0177783B1 (en) 1994-09-21
HU198733B (en) 1989-11-28
EP0429430B1 (en) 1993-09-15
DK165046B (da) 1992-10-05
FI83963B (fi) 1991-06-14
ATE94396T1 (de) 1993-10-15
DE3587587T2 (de) 1994-03-31
JPS6328411B2 (ko) 1988-06-08
DE3587928D1 (de) 1994-10-27
US4698332A (en) 1987-10-06
KR880001234B1 (ko) 1988-07-12
ATE111738T1 (de) 1994-10-15
AU582584B2 (en) 1989-04-06
HU197515B (en) 1989-04-28
ES8606323A1 (es) 1986-04-16
DK165046C (da) 1993-02-22
FI853456A0 (fi) 1985-09-10
AU4719985A (en) 1986-03-20
CN85108388A (zh) 1987-06-03
ES546840A0 (es) 1986-04-16
ZA856905B (en) 1986-06-25
FI83963C (fi) 1991-09-25
DK413785A (da) 1986-03-12
HUT40804A (en) 1987-02-27
DK413785D0 (da) 1985-09-11
CA1246452A (en) 1988-12-13
CN85108388B (zh) 1988-08-24
DE3587928T2 (de) 1995-01-26

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