KR880007060A - 제약 조성물 - Google Patents
제약 조성물 Download PDFInfo
- Publication number
- KR880007060A KR880007060A KR870014136A KR870014136A KR880007060A KR 880007060 A KR880007060 A KR 880007060A KR 870014136 A KR870014136 A KR 870014136A KR 870014136 A KR870014136 A KR 870014136A KR 880007060 A KR880007060 A KR 880007060A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- composition according
- ranitidine
- formulation
- ethanol
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 claims 5
- 229960000620 ranitidine Drugs 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000012458 free base Substances 0.000 claims 3
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical class N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000000337 buffer salt Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Furan Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (12)
- 라니티딘 및(또는) 하나 이상의 그의 생리학적으로 허용되는 염의 수용액 제제물로서, 제제물이 또한 에탄올을 함유하는 것을 특징으로 하는 제약 조성물.
- 제1항에 있어서, 완전한 제제물에 기초해서 에탄올을 2.5% 내지 10중량%/용적% 함유하는 제약 조성물.
- 제1항에 있어서, 완전한 제제물에 기초해서 에탄올을 7% 내지 8중량/용적% 함유하는 제약 조성물.
- 제1항 내지 3항 중 어느 하나의 항에 있어서, pH6.5 내지 7.5를 갖는 제약 조성물.
- 제1항 내지 3항 중 어느 하나의 항에 있어서, pH6.8 내지 7.4를 갖는 제약 조성물.
- 제1항 내지 3항 중 어느 하나의 항에 있어서, pH7.0 내지 7.3를 갖는 제약 조성물.
- 제4항 내지 6항 중 어느 하나의 항에 있어서, pH를 완충염의 사용에 의해 얻는 것을 특징으로 하는 제약 조성물.
- 제1항 내지 7항 중 어느 하나의 항에 있어서, 경구 투여에 적합한 제약 조성물.
- 제8항에 있어서, 유리 염기로 표시되는 복용량 10ml당 라니티딘 20-400mg을 함유하는 제약 조성물.
- 제8항에 있어서, 유리 염기로 표시되는 복용량 10ml당 라니티딘 20-200mg을 함유하는 제약 조성물.
- 제8항에 있어서, 유리 염기로 표시되는 복용량 10ml당 라니티딘 150mg을 함유하는 제약 조성물.
- 제1항 내지 11항 중 어느 하나의 항에 있어서, 라니티딘을 염산염 염의 형태로 사용해서 제조한 제약 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629781A GB8629781D0 (en) | 1986-12-12 | 1986-12-12 | Pharmaceutical compositions |
GB8629781 | 1986-12-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880007060A true KR880007060A (ko) | 1988-08-26 |
KR960008228B1 KR960008228B1 (ko) | 1996-06-21 |
Family
ID=10608930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870014136A KR960008228B1 (ko) | 1986-12-12 | 1987-12-11 | 라니티딘 제약 조성물 |
Country Status (23)
Country | Link |
---|---|
US (1) | US5068249A (ko) |
JP (1) | JP2590156B2 (ko) |
KR (1) | KR960008228B1 (ko) |
AT (1) | AT395373B (ko) |
AU (1) | AU607451B2 (ko) |
BE (1) | BE1000624A5 (ko) |
CA (1) | CA1303993C (ko) |
CH (1) | CH675207A5 (ko) |
CZ (1) | CZ281599B6 (ko) |
DE (1) | DE3742127C2 (ko) |
DK (1) | DK167842B1 (ko) |
FR (1) | FR2608921B1 (ko) |
GB (2) | GB8629781D0 (ko) |
HK (1) | HK19095A (ko) |
IE (1) | IE60618B1 (ko) |
IL (1) | IL84795A0 (ko) |
IT (1) | IT1211967B (ko) |
NL (1) | NL194431C (ko) |
NZ (1) | NZ222879A (ko) |
PH (1) | PH25390A (ko) |
SE (1) | SE504333C2 (ko) |
YU (1) | YU46561B (ko) |
ZA (1) | ZA879338B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100412290B1 (ko) * | 2001-11-27 | 2003-12-31 | 주식회사 동구제약 | 라니티딘 함유 현탁제 조성물 및 그의 제조방법 |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8925484D0 (en) * | 1989-11-10 | 1989-12-28 | Glaxo Group Ltd | Process |
GB9019875D0 (en) * | 1990-09-11 | 1990-10-24 | Glaxo Group Ltd | Pharmaceutical compositions |
US5169864A (en) * | 1991-11-15 | 1992-12-08 | Baxter International Inc. | Unbuffered premixed ranitidine formulation |
WO1995010274A1 (en) * | 1993-10-14 | 1995-04-20 | F.H. Faulding & Co. Limited | Aqueous pharmaceutical composition |
US5407687A (en) * | 1994-02-22 | 1995-04-18 | Glaxo Inc. | Ranitidine solid dosage form |
WO1996001129A1 (en) * | 1994-07-06 | 1996-01-18 | Farmarc Nederland B.V. | Inclusion complexes of ranitidine |
HU213598B (en) * | 1994-10-18 | 1997-08-28 | Ge Lighting Tungsram Rt | One-side socketed discharge lamp |
US5538737A (en) * | 1994-11-30 | 1996-07-23 | Applied Analytical Industries, Inc. | Oral compositions of H2 -antagonists |
US5976578A (en) * | 1996-10-10 | 1999-11-02 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
GB9715423D0 (en) | 1997-07-23 | 1997-09-24 | Glaxo Group Ltd | Aqueous compositions |
US20060100271A1 (en) * | 2004-11-08 | 2006-05-11 | Keith Whitehead | Stabilized aqueous ranitidine compositions |
ES2382993T3 (es) | 2006-07-21 | 2012-06-15 | Lyne Laboratories, Inc. | Composición líquida de acetato de calcio |
GR1009069B (el) * | 2015-01-05 | 2017-07-07 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας & Αναπτυξης Α.Ε. | Ποσιμα διαλυματα υψηλης συγκεντρωσης που περιεχουν υδροχλωρικη ρανιτιδινη |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2735587A1 (de) * | 1977-08-06 | 1979-02-15 | Sandoz Ag | Stabile loesungen und verfahren zu deren herstellung |
GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
DE3108753A1 (de) * | 1981-03-07 | 1982-09-16 | Degussa Ag, 6000 Frankfurt | Neue substituierte alkyl-phenylsulfonylguanidine miteinem heterocyclischen rest |
CA1211374A (en) * | 1982-05-14 | 1986-09-16 | Eszter Cholnoky | Pharmaceutical compositions containing more active ingredients |
JPS59101478A (ja) * | 1982-11-29 | 1984-06-12 | Sunstar Inc | リグスチライドを安定に配合した水系組成物 |
GB8313217D0 (en) * | 1983-05-13 | 1983-06-22 | Glaxo Group Ltd | Pharmaceutical compositions |
SE8704436D0 (sv) * | 1987-11-13 | 1987-11-13 | Pm Konsult Handelsbolag | Anvendning av antisekretoriska substanser for nya indikationer |
-
1986
- 1986-12-12 GB GB868629781A patent/GB8629781D0/en active Pending
-
1987
- 1987-12-11 AU AU82444/87A patent/AU607451B2/en not_active Expired
- 1987-12-11 PH PH36204A patent/PH25390A/en unknown
- 1987-12-11 JP JP62312419A patent/JP2590156B2/ja not_active Expired - Fee Related
- 1987-12-11 FR FR878717295A patent/FR2608921B1/fr not_active Expired - Lifetime
- 1987-12-11 ZA ZA879338A patent/ZA879338B/xx unknown
- 1987-12-11 SE SE8704952A patent/SE504333C2/sv not_active IP Right Cessation
- 1987-12-11 IE IE336787A patent/IE60618B1/en not_active IP Right Cessation
- 1987-12-11 CA CA000554086A patent/CA1303993C/en not_active Expired - Lifetime
- 1987-12-11 GB GB8728957A patent/GB2198352B/en not_active Expired - Lifetime
- 1987-12-11 NZ NZ222879A patent/NZ222879A/xx unknown
- 1987-12-11 IT IT8748698A patent/IT1211967B/it active
- 1987-12-11 IL IL84795A patent/IL84795A0/xx not_active IP Right Cessation
- 1987-12-11 NL NL8703000A patent/NL194431C/nl not_active IP Right Cessation
- 1987-12-11 DE DE3742127A patent/DE3742127C2/de not_active Expired - Lifetime
- 1987-12-11 YU YU224587A patent/YU46561B/sh unknown
- 1987-12-11 AT AT0327387A patent/AT395373B/de not_active IP Right Cessation
- 1987-12-11 KR KR1019870014136A patent/KR960008228B1/ko not_active IP Right Cessation
- 1987-12-11 CH CH4842/87A patent/CH675207A5/fr not_active IP Right Cessation
- 1987-12-11 DK DK652787A patent/DK167842B1/da not_active IP Right Cessation
- 1987-12-11 BE BE8701417A patent/BE1000624A5/fr not_active IP Right Cessation
-
1990
- 1990-03-14 US US07/494,804 patent/US5068249A/en not_active Expired - Lifetime
-
1991
- 1991-12-23 CZ CS914037A patent/CZ281599B6/cs not_active IP Right Cessation
-
1995
- 1995-02-09 HK HK19095A patent/HK19095A/xx not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100412290B1 (ko) * | 2001-11-27 | 2003-12-31 | 주식회사 동구제약 | 라니티딘 함유 현탁제 조성물 및 그의 제조방법 |
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Payment date: 20100531 Year of fee payment: 15 |
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