KR890015745A - 수용액으로 존재하는 피록시캄의 제약 조성물 및 그의 제조방법 - Google Patents
수용액으로 존재하는 피록시캄의 제약 조성물 및 그의 제조방법 Download PDFInfo
- Publication number
- KR890015745A KR890015745A KR1019890004209A KR890004209A KR890015745A KR 890015745 A KR890015745 A KR 890015745A KR 1019890004209 A KR1019890004209 A KR 1019890004209A KR 890004209 A KR890004209 A KR 890004209A KR 890015745 A KR890015745 A KR 890015745A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- aqueous solution
- active ingredient
- present
- pyricampum
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 5
- 239000007864 aqueous solution Substances 0.000 title claims 4
- 238000002360 preparation method Methods 0.000 title 1
- 239000004480 active ingredient Substances 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000003513 alkali Substances 0.000 claims 1
- 229910001854 alkali hydroxide Inorganic materials 0.000 claims 1
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 239000008215 water for injection Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 수용액으로 존재하는 피록시캄의 주사용 또는 눈투여용 제약 조성물.
- 제 1 항에 있어서, 즉시 사용가능한 용액 형태 또는 사용 직전 주사용수에 용해시키는 동결건조 형태로 투여량 단위 당 유효 성분 10 내지 30mg을 함유하는 주사용 제약 조성물.
- 제 1 항에 있어서, 유효 성분의 농도가 0.2 내지 1%인 눈 투여용 제약 조성물.
- (a) 유효 성분을 물 중에 1 내지 4%(중량/용적)의 농도로 분산시키고, (b) 화학량론적 양의 알칼리 금속 또는 알칼리토금속의 수산화물 수용액을 완전 용해되도록 교반하면서 상기 수용액에 첨가하고, (c) pH 안정화제로서 글리코콜을 8 내지 10%(중량/용적) 범위의 양으로 수용액에 첨가하는 것을 특징으로 하는, 제1 내지 3항중 어느 하나의 항에 의해 제약 조성물의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20073A/88 | 1988-04-01 | ||
IT8820073A IT1216686B (it) | 1988-04-01 | 1988-04-01 | Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione. |
Publications (1)
Publication Number | Publication Date |
---|---|
KR890015745A true KR890015745A (ko) | 1989-11-25 |
Family
ID=11163585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890004209A KR890015745A (ko) | 1988-04-01 | 1989-03-31 | 수용액으로 존재하는 피록시캄의 제약 조성물 및 그의 제조방법 |
Country Status (19)
Country | Link |
---|---|
US (1) | US4942167A (ko) |
EP (1) | EP0336200B1 (ko) |
JP (1) | JPH01299230A (ko) |
KR (1) | KR890015745A (ko) |
AT (1) | ATE85757T1 (ko) |
AU (1) | AU608142B2 (ko) |
CA (1) | CA1321352C (ko) |
DE (2) | DE68904922T2 (ko) |
DK (1) | DK157689A (ko) |
ES (1) | ES2011232T3 (ko) |
FI (1) | FI90202C (ko) |
GR (2) | GR890300196T1 (ko) |
IE (1) | IE63714B1 (ko) |
IT (1) | IT1216686B (ko) |
MA (1) | MA21527A1 (ko) |
NO (1) | NO175406C (ko) |
NZ (1) | NZ228576A (ko) |
PT (1) | PT90124B (ko) |
ZA (1) | ZA892399B (ko) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1241088B (it) * | 1990-03-27 | 1993-12-29 | Chiesi Farma Spa | Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche |
HU205550B (en) * | 1990-11-27 | 1992-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pyroxycam solution of increased stability, free from effects damaging tussues |
US5362758A (en) * | 1992-09-18 | 1994-11-08 | Pfizer Inc. | Ophthalmic piroxicam solution |
US5420124A (en) * | 1994-01-12 | 1995-05-30 | Kim; Young S. | Stable, painless piroxicam potassium injectable composition |
CN1047077C (zh) * | 1994-01-15 | 1999-12-08 | 金元圭 | 稳定、无痛的吡罗昔康钾可注射组合物 |
US5807568A (en) * | 1994-12-27 | 1998-09-15 | Mcneil-Ppc, Inc. | Enhanced delivery of topical compositions containing flurbiprofen |
IT1283252B1 (it) * | 1996-03-15 | 1998-04-16 | Pulitzer Italiana | Soluzioni di piroxicam iniettabili per via parenterale |
DK0909562T3 (da) * | 1996-07-03 | 2005-08-22 | Eisai Co Ltd | Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf |
US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
DE10161077A1 (de) * | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
US8992980B2 (en) * | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
JP4674162B2 (ja) * | 2003-11-14 | 2011-04-20 | 千寿製薬株式会社 | アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤 |
EP1568369A1 (en) * | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
WO2007039417A1 (en) * | 2005-09-30 | 2007-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical preparation containing meloxicam |
CN102647971B (zh) | 2009-10-12 | 2016-03-16 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 用于包含美洛昔康的组合物的容器 |
WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
US20110218191A1 (en) * | 2010-03-03 | 2011-09-08 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long term-treatment of kidney disorders in cats |
DE102010014290A1 (de) * | 2010-04-08 | 2011-10-13 | Hans Otto Meyer zu Spelbrink | Mittel zur prophylaktischen und therapeutischen Behandlung von Herpes-Infektionen |
US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
CA3132227A1 (en) * | 2019-03-01 | 2020-09-10 | Eurofarma Laboratorios S.A. | Non-steroid anti-inflammatory pharmaceutical composition |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE421792B (sv) * | 1976-01-12 | 1982-02-01 | Pfizer | Forfarande for framstellning av n-(2-pyridyl)-4-hydroxi-2-metyl-2h-1,2-benso-tiazin-3-karboxamid-1,1-dioxid |
-
1988
- 1988-04-01 IT IT8820073A patent/IT1216686B/it active Protection Beyond IP Right Term
-
1989
- 1989-03-21 AT AT89105004T patent/ATE85757T1/de not_active IP Right Cessation
- 1989-03-21 EP EP89105004A patent/EP0336200B1/en not_active Expired - Lifetime
- 1989-03-21 ES ES89105004T patent/ES2011232T3/es not_active Expired - Lifetime
- 1989-03-21 DE DE8989105004T patent/DE68904922T2/de not_active Expired - Fee Related
- 1989-03-21 DE DE198989105004T patent/DE336200T1/de active Pending
- 1989-03-28 PT PT90124A patent/PT90124B/pt not_active IP Right Cessation
- 1989-03-28 MA MA21773A patent/MA21527A1/fr unknown
- 1989-03-29 JP JP1077949A patent/JPH01299230A/ja active Pending
- 1989-03-31 IE IE103289A patent/IE63714B1/en not_active IP Right Cessation
- 1989-03-31 DK DK157689A patent/DK157689A/da not_active IP Right Cessation
- 1989-03-31 NZ NZ228576A patent/NZ228576A/en unknown
- 1989-03-31 CA CA000595421A patent/CA1321352C/en not_active Expired - Fee Related
- 1989-03-31 FI FI891570A patent/FI90202C/fi not_active IP Right Cessation
- 1989-03-31 US US07/331,457 patent/US4942167A/en not_active Expired - Fee Related
- 1989-03-31 NO NO891367A patent/NO175406C/no unknown
- 1989-03-31 AU AU32297/89A patent/AU608142B2/en not_active Ceased
- 1989-03-31 ZA ZA892399A patent/ZA892399B/xx unknown
- 1989-03-31 KR KR1019890004209A patent/KR890015745A/ko active IP Right Grant
-
1990
- 1990-11-29 GR GR89300196T patent/GR890300196T1/el unknown
-
1993
- 1993-02-18 GR GR930400298T patent/GR3007107T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI90202C (fi) | 1994-01-10 |
CA1321352C (en) | 1993-08-17 |
MA21527A1 (fr) | 1989-10-01 |
NO891367D0 (no) | 1989-03-31 |
GR3007107T3 (ko) | 1993-07-30 |
IE891032L (en) | 1989-10-01 |
EP0336200A1 (en) | 1989-10-11 |
NO175406B (no) | 1994-07-04 |
ES2011232A4 (es) | 1990-01-01 |
FI891570A (fi) | 1989-10-02 |
DK157689D0 (da) | 1989-03-31 |
DK157689A (da) | 1989-10-02 |
NO175406C (no) | 1994-10-12 |
DE68904922D1 (de) | 1993-03-25 |
NO891367L (no) | 1989-10-02 |
IE63714B1 (en) | 1995-05-31 |
DE68904922T2 (de) | 1993-06-03 |
AU3229789A (en) | 1989-10-05 |
NZ228576A (en) | 1990-10-26 |
EP0336200B1 (en) | 1993-02-17 |
IT1216686B (it) | 1990-03-08 |
ES2011232T3 (es) | 1994-01-16 |
ATE85757T1 (de) | 1993-03-15 |
AU608142B2 (en) | 1991-03-21 |
PT90124B (pt) | 1994-06-30 |
DE336200T1 (de) | 1990-03-01 |
ZA892399B (en) | 1989-11-29 |
PT90124A (pt) | 1989-11-10 |
US4942167A (en) | 1990-07-17 |
FI90202B (fi) | 1993-09-30 |
JPH01299230A (ja) | 1989-12-04 |
GR890300196T1 (en) | 1990-11-29 |
IT8820073A0 (it) | 1988-04-01 |
FI891570A0 (fi) | 1989-03-31 |
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A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
NORF | Unpaid initial registration fee |