KR890012960A - 결정성 β-락탐 용매화물 - Google Patents
결정성 β-락탐 용매화물 Download PDFInfo
- Publication number
- KR890012960A KR890012960A KR1019890001185A KR890001185A KR890012960A KR 890012960 A KR890012960 A KR 890012960A KR 1019890001185 A KR1019890001185 A KR 1019890001185A KR 890001185 A KR890001185 A KR 890001185A KR 890012960 A KR890012960 A KR 890012960A
- Authority
- KR
- South Korea
- Prior art keywords
- crystalline
- compound
- formula
- hydrate
- lactam
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 하기 구조식(Ⅰ) 화합물의 결정성 2.5 수화물.
- 활성 성분으로서 제1항에서 청구된 구조식(Ⅰ) 화합물의 결정성 2.5 수화물을 하나 이상의 약제학적으로 허용되는 담체, 비히클 또는 부형제와의 혼합물 형태로 함유함을 특징으로 하는 약제학적 제형.
- 구조식(Ⅰ)의 화합물을 함유하는 수용액을 동결 건조시키고 그 결과 생성된 고체를 물로 결정화 시킴을 특징으로 하여, 제1항에서 청구한 구조식(Ⅰ) 화합물의 결정성 2.5 수화물을 제조하는 방법.
- 제3항의 방법에 의해 제조되는, 제1항에서 청구된 구조식(Ⅰ) 화합물의 결정성 2.5 수화물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15277788A | 1988-02-05 | 1988-02-05 | |
| US07/152777 | 1988-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR890012960A true KR890012960A (ko) | 1989-09-20 |
Family
ID=22544405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019890001185A KR890012960A (ko) | 1988-02-05 | 1989-02-02 | 결정성 β-락탐 용매화물 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0327364A1 (ko) |
| JP (1) | JPH021489A (ko) |
| KR (1) | KR890012960A (ko) |
| CN (1) | CN1034929A (ko) |
| AU (1) | AU615026B2 (ko) |
| DK (1) | DK49989A (ko) |
| HU (1) | HU204271B (ko) |
| IL (1) | IL89150A0 (ko) |
| NZ (1) | NZ227842A (ko) |
| PT (1) | PT89612A (ko) |
| SU (1) | SU1750429A3 (ko) |
| ZA (1) | ZA89829B (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
| CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
| AU1234999A (en) * | 1997-11-10 | 1999-05-31 | Gist-Brocades B.V. | Crystallization of beta-lactam compounds |
| US7378408B2 (en) | 2001-11-30 | 2008-05-27 | Pfizer Inc. | Methods of treatment and formulations of cephalosporin |
| CN100334061C (zh) * | 2002-11-05 | 2007-08-29 | 立德化学株式会社 | 紫外线防御化合物 |
| JP2013510097A (ja) * | 2009-11-03 | 2013-03-21 | リウ、リー | タンシノンｉｉａスルホン酸ナトリウム水和物、並びにその調製方法及び使用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
| NZ222015A (en) * | 1986-10-03 | 1989-10-27 | Lilly Co Eli | 7-(meta-substituted phenylglycine)-1-carba-1-dethiacephalsporins and pharmaceutical compositions |
-
1989
- 1989-02-02 ZA ZA89829A patent/ZA89829B/xx unknown
- 1989-02-02 IL IL89150A patent/IL89150A0/xx unknown
- 1989-02-02 HU HU89527A patent/HU204271B/hu not_active IP Right Cessation
- 1989-02-02 EP EP89301011A patent/EP0327364A1/en not_active Withdrawn
- 1989-02-02 NZ NZ227842A patent/NZ227842A/en unknown
- 1989-02-02 KR KR1019890001185A patent/KR890012960A/ko not_active Application Discontinuation
- 1989-02-02 SU SU894613379A patent/SU1750429A3/ru active
- 1989-02-03 AU AU29619/89A patent/AU615026B2/en not_active Expired - Fee Related
- 1989-02-03 PT PT89612A patent/PT89612A/pt not_active Application Discontinuation
- 1989-02-03 JP JP1026523A patent/JPH021489A/ja active Pending
- 1989-02-03 DK DK049989A patent/DK49989A/da not_active Application Discontinuation
- 1989-02-03 CN CN89100760A patent/CN1034929A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2961989A (en) | 1989-08-10 |
| HU204271B (en) | 1991-12-30 |
| DK49989A (da) | 1989-08-07 |
| SU1750429A3 (ru) | 1992-07-23 |
| HUT49616A (en) | 1989-10-30 |
| DK49989D0 (da) | 1989-02-03 |
| PT89612A (pt) | 1989-10-04 |
| IL89150A0 (en) | 1989-09-10 |
| AU615026B2 (en) | 1991-09-19 |
| CN1034929A (zh) | 1989-08-23 |
| EP0327364A1 (en) | 1989-08-09 |
| NZ227842A (en) | 1990-12-21 |
| ZA89829B (en) | 1990-10-31 |
| JPH021489A (ja) | 1990-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |