IT1241088B - Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche - Google Patents

Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche

Info

Publication number
IT1241088B
IT1241088B IT19829A IT1982990A IT1241088B IT 1241088 B IT1241088 B IT 1241088B IT 19829 A IT19829 A IT 19829A IT 1982990 A IT1982990 A IT 1982990A IT 1241088 B IT1241088 B IT 1241088B
Authority
IT
Italy
Prior art keywords
complexes
piroxicam
pharmaceutical compositions
products obtained
cyclodestrine
Prior art date
Application number
IT19829A
Other languages
English (en)
Other versions
IT9019829A1 (it
IT9019829A0 (it
Inventor
Fabio Carli
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of IT9019829A0 publication Critical patent/IT9019829A0/it
Priority to IT19829A priority Critical patent/IT1241088B/it
Priority to IE096991A priority patent/IE910969A1/en
Priority to MA22366A priority patent/MA22089A1/fr
Priority to ES91104649T priority patent/ES2107430T3/es
Priority to AT91104649T priority patent/ATE157883T1/de
Priority to DK91104649.8T priority patent/DK0449167T3/da
Priority to NO911216A priority patent/NO178456C/no
Priority to EP91104649A priority patent/EP0449167B1/en
Priority to DE69127566T priority patent/DE69127566T2/de
Priority to FI911448A priority patent/FI102461B/fi
Priority to CA002039052A priority patent/CA2039052C/en
Priority to AU73838/91A priority patent/AU644417B2/en
Priority to SU4895029/14A priority patent/RU2034544C1/ru
Priority to NZ237583A priority patent/NZ237583A/en
Priority to ZA912282A priority patent/ZA912282B/xx
Priority to PT97176A priority patent/PT97176B/pt
Priority to JP3085783A priority patent/JPH04221314A/ja
Priority to IL9769391A priority patent/IL97693A/en
Priority to US07/676,070 priority patent/US5164380A/en
Priority to KR1019910004755A priority patent/KR0175934B1/ko
Priority to CS91833A priority patent/CZ280164B6/cs
Priority to HU016/91A priority patent/HU217834B/hu
Priority to SK833-91A priority patent/SK279171B6/sk
Publication of IT9019829A1 publication Critical patent/IT9019829A1/it
Application granted granted Critical
Publication of IT1241088B publication Critical patent/IT1241088B/it
Priority to GR970402947T priority patent/GR3025305T3/el

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
IT19829A 1990-03-27 1990-03-27 Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche IT1241088B (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT19829A IT1241088B (it) 1990-03-27 1990-03-27 Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche
IE096991A IE910969A1 (en) 1990-03-27 1991-03-22 Process for preparing piroxicam/cyclodextrin complexes, the¹products obtained and their pharmaceutical compositions
MA22366A MA22089A1 (fr) 1990-03-27 1991-03-25 Procede de preparation de complexes de piroxicame/cyclodextrine, les produits obtenus et leurs compositions pharmaceutiques
ES91104649T ES2107430T3 (es) 1990-03-27 1991-03-25 Procedimiento para preparar complejos de piroxicam/ciclodextrina, los productos obtenidos y sus composiciones farmaceuticas.
AT91104649T ATE157883T1 (de) 1990-03-27 1991-03-25 Verfahren zur herstellung von piroxicam/cyclodextrin-komplexen, die erhaltenen produkte und ihre pharmazeutischen zusammensetzungen
DK91104649.8T DK0449167T3 (da) 1990-03-27 1991-03-25 Fremgangsmåde til fremstilling af piroxicam/cyclodextrin-komplekser, de opnåede produkter og deres farmaceutiske præparater
NO911216A NO178456C (no) 1990-03-27 1991-03-25 Fremgangsmåte for fremstilling av farmasöytisk aktive piroksikam/syklodekstrinkomplekser
EP91104649A EP0449167B1 (en) 1990-03-27 1991-03-25 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions
DE69127566T DE69127566T2 (de) 1990-03-27 1991-03-25 Verfahren zur Herstellung von Piroxicam/Cyclodextrin-Komplexen, die erhaltenen Produkte und ihre pharmazeutischen Zusammensetzungen
SU4895029/14A RU2034544C1 (ru) 1990-03-27 1991-03-26 Пироксикам-циклодекстриновый комплекс, обладающий болеутоляющим, противовоспалительным и антиревматическим действием, способ его получения и фармацевтическая композиция, обладающая болеутоляющим, противовоспалительным и антиревматическим действием
CA002039052A CA2039052C (en) 1990-03-27 1991-03-26 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions
AU73838/91A AU644417B2 (en) 1990-03-27 1991-03-26 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions
FI911448A FI102461B (fi) 1990-03-27 1991-03-26 Menetelmä piroksikaami-syklodekstriinikompleksien valmistamiseksi
NZ237583A NZ237583A (en) 1990-03-27 1991-03-26 Preparation of piroxicam - cyclodextrin complexes and pharmaceutical compositions thereof
ZA912282A ZA912282B (en) 1990-03-27 1991-03-26 Process for preparing piroxicam/cyclodextrin complexes,the products obtained and their pharmaceutical compositions
US07/676,070 US5164380A (en) 1990-03-27 1991-03-27 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions
JP3085783A JPH04221314A (ja) 1990-03-27 1991-03-27 ピロキシカム／シクロデキストリン複合体の調製方法、得られた生成物及びそれらの製薬組成物
IL9769391A IL97693A (en) 1990-03-27 1991-03-27 Preparation of cycloxemic cyclodextrin complexes, the resulting products and the pharmaceutical preparations containing them
PT97176A PT97176B (pt) 1990-03-27 1991-03-27 Processo para a preparacao de complexos de piroxicam/ciclodextrina e de composicoes farmaceuticas
KR1019910004755A KR0175934B1 (ko) 1990-03-27 1991-03-27 피록시캄/사이클로덱스트린 복합체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
CS91833A CZ280164B6 (cs) 1990-03-27 1991-03-27 Způsob výroby komplexů piroxicamu a cyklodextrinu získané komplexy a farmaceutické prostředky s jejich obsahem
HU016/91A HU217834B (hu) 1990-03-27 1991-03-27 Piroxicam/ciklodextrin komplexeket tartalmazó, gyorsan széteső tabletták és eljárás ezek előállítására
SK833-91A SK279171B6 (sk) 1990-03-27 1991-03-27 Komplex piroxicamu a cyklodextrínu, spôsob jeho vý
GR970402947T GR3025305T3 (en) 1990-03-27 1997-11-07 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19829A IT1241088B (it) 1990-03-27 1990-03-27 Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche

Publications (3)

Publication Number Publication Date
IT9019829A0 IT9019829A0 (it) 1990-03-27
IT9019829A1 IT9019829A1 (it) 1991-09-27
IT1241088B true IT1241088B (it) 1993-12-29

Family

ID=11161628

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19829A IT1241088B (it) 1990-03-27 1990-03-27 Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche

Country Status (24)

Country Link
US (1) US5164380A (it)
EP (1) EP0449167B1 (it)
JP (1) JPH04221314A (it)
KR (1) KR0175934B1 (it)
AT (1) ATE157883T1 (it)
AU (1) AU644417B2 (it)
CA (1) CA2039052C (it)
CZ (1) CZ280164B6 (it)
DE (1) DE69127566T2 (it)
DK (1) DK0449167T3 (it)
ES (1) ES2107430T3 (it)
FI (1) FI102461B (it)
GR (1) GR3025305T3 (it)
HU (1) HU217834B (it)
IE (1) IE910969A1 (it)
IL (1) IL97693A (it)
IT (1) IT1241088B (it)
MA (1) MA22089A1 (it)
NO (1) NO178456C (it)
NZ (1) NZ237583A (it)
PT (1) PT97176B (it)
RU (1) RU2034544C1 (it)
SK (1) SK279171B6 (it)
ZA (1) ZA912282B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254541A (en) * 1991-11-15 1993-10-19 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indole/cyclodextrin complex
IL111184A (en) * 1993-10-08 2000-08-13 Farmarc Nederland B V Of Cito Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin
ZA959469B (en) * 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
IT1295289B1 (it) * 1997-10-07 1999-05-04 Telos S R L Co-macinati per uso cosmetico e dermatologico
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
DE69914742T2 (de) 1998-05-29 2004-11-25 Skyepharma Canada Inc., Verdun Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
ID29270A (id) * 1998-11-20 2001-08-16 Rtp Pharma Inc Partikel-partikel mikro yang distabilkan oleh fosfolipid yang dapat menyebar
US20060073188A1 (en) * 1999-03-31 2006-04-06 Pierre Fabre Medicament Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same
ITMI20012749A1 (it) * 2001-12-21 2003-06-21 Chiesi Farma Spa Procedimento per la preparazione mediante trattamento con microonde di composti di inclusione tra farmaco e ciclodestrine e prodotti ottenut
ATE504316T1 (de) 2004-04-01 2011-04-15 Pf Medicament Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin
FR2868315B1 (fr) * 2004-04-01 2006-07-14 Pierre Fabre Medicament Sa Procede de preparation d'un compose d'inclusion soluble de substances actives dans une molecule hote avec l'aide d'un agent d'interaction par fluide supercritique
US8715731B2 (en) * 2006-03-22 2014-05-06 Isp Investments Inc. Process of reducing the bitter taste of water soluble actives by co-grinding the active with β cyclodextrin
JP5552400B2 (ja) * 2010-09-07 2014-07-16 東亜薬品株式会社 生薬類の苦味・不快味をマスキングした顆粒剤、及び口腔内速崩壊錠
CN102008450B (zh) * 2010-12-10 2013-01-30 杭州艾瑞莎生物医药科技有限公司 一种药物-环糊精纳米颗粒及其制备方法
ITMI20120092A1 (it) 2012-01-26 2013-07-27 Micro Macinazione S A Compositi di inclusione farmaco-carrier preparati con processo di attivazione meccano-chimica mediante mulini a getto di fluido ad alta energia
ITUB20161027A1 (it) * 2016-02-24 2017-08-24 Altergon Sa Preparazioni farmaceutiche oromucosali ad elevata biodisponibilita’ a base di ciclodestrina e sucralosio
US10532102B2 (en) 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses
KR102337124B1 (ko) * 2021-05-13 2021-12-10 (주)바이오제닉스 탈모 개선용 복합 파우더 및 이를 포함하는 모발용 화장료 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
JPS6165805A (ja) * 1984-09-10 1986-04-04 Nippon Ekishiyou Kk 防殺虫フイルムの製造方法
US4579846A (en) * 1984-10-11 1986-04-01 Pfizer Inc. Antiinflammatory compositions and methods
US4672061A (en) * 1985-01-28 1987-06-09 Pfizer Inc. Antiinflammatory compositions and methods
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
US4888343A (en) * 1986-09-15 1989-12-19 Bristol-Myers Company Pharmaceutical compositions for relief of dysmenorrhea and/or premenstrual syndrome and process
WO1989003682A1 (en) * 1987-10-26 1989-05-05 Pfizer Inc. Benzothiazine dioxide derivatives
US5068226A (en) * 1987-12-07 1991-11-26 Cyclex, Inc. Pharmaceutical preparations containing cyclodextrins and their use in iontophoretic therapies
IT1216686B (it) * 1988-04-01 1990-03-08 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
CA1321192C (en) * 1988-04-20 1993-08-10 Abdul Majid Inclusion complexes of cyclodextrins by agglomeration
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione

Also Published As

Publication number Publication date
FI102461B1 (fi) 1998-12-15
NO911216D0 (no) 1991-03-25
DE69127566T2 (de) 1998-02-12
NO178456C (no) 1996-04-03
NZ237583A (en) 1992-08-26
HUT60738A (en) 1992-10-28
ATE157883T1 (de) 1997-09-15
NO178456B (no) 1995-12-27
IT9019829A1 (it) 1991-09-27
ZA912282B (en) 1991-12-24
IL97693A0 (en) 1992-06-21
FI102461B (fi) 1998-12-15
IE910969A1 (en) 1991-10-09
HU217834B (hu) 2000-04-28
CA2039052A1 (en) 1991-09-28
KR0175934B1 (ko) 1999-03-20
NO911216L (no) 1991-09-30
AU644417B2 (en) 1993-12-09
KR910016333A (ko) 1991-11-05
US5164380A (en) 1992-11-17
RU2034544C1 (ru) 1995-05-10
EP0449167A1 (en) 1991-10-02
PT97176A (pt) 1991-11-29
ES2107430T3 (es) 1997-12-01
CA2039052C (en) 2002-07-30
FI911448A (fi) 1991-09-28
AU7383891A (en) 1991-10-03
SK279171B6 (sk) 1998-07-08
IT9019829A0 (it) 1990-03-27
EP0449167B1 (en) 1997-09-10
HU911016D0 (en) 1991-10-28
PT97176B (pt) 1998-07-31
GR3025305T3 (en) 1998-02-27
DK0449167T3 (da) 1998-03-09
MA22089A1 (fr) 1991-10-01
FI911448A0 (fi) 1991-03-26
DE69127566D1 (de) 1997-10-16
CS9100833A2 (en) 1991-10-15
CZ280164B6 (cs) 1995-11-15
IL97693A (en) 1995-03-30
JPH04221314A (ja) 1992-08-11

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970427