ATE504316T1 - Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin - Google Patents

Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin

Info

Publication number
ATE504316T1
ATE504316T1 AT05744579T AT05744579T ATE504316T1 AT E504316 T1 ATE504316 T1 AT E504316T1 AT 05744579 T AT05744579 T AT 05744579T AT 05744579 T AT05744579 T AT 05744579T AT E504316 T1 ATE504316 T1 AT E504316T1
Authority
AT
Austria
Prior art keywords
cyclodextrin
arginine
complexes containing
inclusion complexes
containing piroxicam
Prior art date
Application number
AT05744579T
Other languages
English (en)
Inventor
Bernard Freiss
Florence Marciacq
Hubert Lochard
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0403450A external-priority patent/FR2868315B1/fr
Priority claimed from FR0411201A external-priority patent/FR2876911B1/fr
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of ATE504316T1 publication Critical patent/ATE504316T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
AT05744579T 2004-04-01 2005-03-29 Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin ATE504316T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0403450A FR2868315B1 (fr) 2004-04-01 2004-04-01 Procede de preparation d'un compose d'inclusion soluble de substances actives dans une molecule hote avec l'aide d'un agent d'interaction par fluide supercritique
FR0411201A FR2876911B1 (fr) 2004-10-21 2004-10-21 Complexe comprenant du piroxicam, une cyclodextrine et de l'arginine
PCT/FR2005/000739 WO2005097201A2 (fr) 2004-04-01 2005-03-29 Complexes d’inclusions comprenant du piroxicam, une cyclodextrine et l’arginine

Publications (1)

Publication Number Publication Date
ATE504316T1 true ATE504316T1 (de) 2011-04-15

Family

ID=34968371

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05744579T ATE504316T1 (de) 2004-04-01 2005-03-29 Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin

Country Status (16)

Country Link
US (2) US8461133B2 (de)
EP (2) EP1729813B1 (de)
JP (1) JP5091661B2 (de)
AR (1) AR049488A1 (de)
AT (1) ATE504316T1 (de)
BR (1) BRPI0509482B1 (de)
CA (1) CA2563101C (de)
CY (1) CY1114198T1 (de)
DE (1) DE602005027333D1 (de)
DK (1) DK2260871T3 (de)
ES (1) ES2424235T3 (de)
PL (2) PL1729813T3 (de)
PT (2) PT1729813E (de)
RU (1) RU2382654C2 (de)
SI (1) SI2260871T1 (de)
WO (1) WO2005097201A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2876914A1 (fr) * 2004-10-21 2006-04-28 Pierre Fabre Medicament Sa Complexe comprenant un antibiotique, une cyclodextrine et un agent d'interaction
FR2876910B1 (fr) 2004-10-21 2007-04-13 Pierre Fabre Medicament Sa Complexe comprenant la mequitazine, une cyclodextrine et un agent d'interaction
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
US20120171184A1 (en) 2010-12-31 2012-07-05 Lajos Szente Cellular hydration compositions
KR101383941B1 (ko) 2012-03-09 2014-04-10 동아에스티 주식회사 피록시캄 또는 약제학적으로 허용되는 그의 염과 히알루론산 또는 약제학적으로 허용되는 그의 염의 안정한 액상 조성물 및 그 제조방법
US10532102B2 (en) * 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses
CN109142420B (zh) * 2018-10-12 2020-01-10 厦门大学 基于核磁共振技术探究药物在胶束内最大增溶量的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434163A (en) 1981-06-01 1984-02-28 Pfizer Inc. Water-soluble benzothiazine dioxide salts
IT1196033B (it) 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
JPS632929A (ja) * 1986-06-20 1988-01-07 Kao Corp アセチルサリチル酸製剤
CA1321192C (en) * 1988-04-20 1993-08-10 Abdul Majid Inclusion complexes of cyclodextrins by agglomeration
KR920006911B1 (ko) * 1989-06-14 1992-08-22 신풍제약 주식회사 안정한 피록시캄 주사액 조성물 및 그의 제조방법
IT1241088B (it) 1990-03-27 1993-12-29 Chiesi Farma Spa Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche
US5366961A (en) * 1990-08-13 1994-11-22 Commonwealth Scientific And Industrial Research Organisation Pesticidal products
EP0519428B1 (de) * 1991-06-21 2000-09-20 Takeda Chemical Industries, Ltd. Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate
AT400674B (de) 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
IT1293764B1 (it) 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
ATE249218T1 (de) 1999-01-06 2003-09-15 Tecnimede Sociedade Tecnico Medicinal Sa Cyclodextrin einschlusskomplexe mit aminosäuresalzen von benzimidazolderivaten, deren herstellung, sowie diese enthaltende pharmazeutische zusammensetzungen
FR2815540B1 (fr) * 2000-10-19 2005-06-10 Separex Sa Procede de fabrication de tres fines particules constituees d'un principe insere dans une molecule hote
WO2002089851A1 (fr) * 2001-03-06 2002-11-14 Separex (Societe Anonyme) Procede de fabrication de complexes hote-client
FR2830761B1 (fr) 2001-10-12 2003-12-12 Pf Medicament Procede de preparation d'un compose d'interaction d'un derive anilide avec un support poreux par fluide supercritique
FR2830760B1 (fr) * 2001-10-12 2004-06-04 Pf Medicament Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
US20050038039A1 (en) * 2002-01-15 2005-02-17 Domenico Fanara Formulations
DE60219609T2 (de) 2002-06-17 2008-01-03 Chiesi Farmaceutici S.P.A. Prozess für die Vorbereitung von Piroxicam: Beta-Cyclodextrin Einschlusskomplexe
FR2854079B1 (fr) * 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires
WO2005112637A1 (en) * 2004-05-14 2005-12-01 Decode Chemistry, Inc. Formulations for non-parenteral use including hydrophobic cyclodextrins

Also Published As

Publication number Publication date
ES2424235T3 (es) 2013-09-30
PL2260871T3 (pl) 2013-10-31
CA2563101A1 (fr) 2005-10-20
DK2260871T3 (da) 2013-08-26
PT2260871E (pt) 2013-08-01
PL1729813T3 (pl) 2011-09-30
EP1729813A2 (de) 2006-12-13
EP2260871B1 (de) 2013-05-15
US9243076B2 (en) 2016-01-26
WO2005097201A3 (fr) 2006-08-17
US8461133B2 (en) 2013-06-11
CA2563101C (fr) 2013-07-02
BRPI0509482A (pt) 2007-09-11
BRPI0509482B1 (pt) 2018-12-11
RU2382654C2 (ru) 2010-02-27
PT1729813E (pt) 2011-07-12
JP5091661B2 (ja) 2012-12-05
CY1114198T1 (el) 2016-08-31
WO2005097201A2 (fr) 2005-10-20
EP2260871A2 (de) 2010-12-15
DE602005027333D1 (de) 2011-05-19
EP1729813B1 (de) 2011-04-06
AR049488A1 (es) 2006-08-09
SI2260871T1 (sl) 2013-09-30
US20070270379A1 (en) 2007-11-22
EP2260871A3 (de) 2011-05-18
JP2007530641A (ja) 2007-11-01
US20130316975A1 (en) 2013-11-28
RU2006138488A (ru) 2008-05-10

Similar Documents

Publication Publication Date Title
ATE504316T1 (de) Einschlusskomplexe enthaltend piroxicam, ein cyklodextrin und arginin
IL187006A0 (en) Ferrocenyl ligands, production and use thereof
DE602005020457D1 (de) Master-slave-flip-flop, trigger-flip-flop und zähler
NO20063607L (no) Barnevogn
HK1102224A1 (en) Stroller and the front arm thereof
TWI372759B (en) A complex comprising mequitazine, a cyclodextrin, and an interaction agent
FI20030426A0 (fi) Syklodekstriinikompleksit
ITTO20040363A1 (it) Contenitore multiplo.
DK1890924T3 (da) Sækkevogn
DE602006017569D1 (de) Pharmazeutische kombinationen mit lamivudin, stavudin und nevirapin
ITPR20050013A1 (it) Trattenitore particolati.
ES1058072Y (es) Toalla-bolso anti-viento.
FR2876911B1 (fr) Complexe comprenant du piroxicam, une cyclodextrine et de l'arginine
ITRM20050497A1 (it) Borsa.
ES1057384Y (es) Carretilla perfeccionada.
ES1058593Y (es) Bolso reconvertible.
UA11705S (uk) Контейнер ктзв-0, 2
ES1059914Y (es) Contenedor abierto.
GB0514532D0 (en) The EFM widget
ITPR20050005U1 (it) Trattenitore particolati.
ES1059074Y (es) Contenedor.
ES1056665Y (es) Contenedor autobasculante.
ES1061002Y (es) Contenedor armable.
CL2007003634S1 (es) Envase.
ITRM20050123U1 (it) Contenitore porta-calendario e diario.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties