DE3587928T2 - N-Acetylneuraminsäure und deren Salze enthaltende Expektorantien. - Google Patents

N-Acetylneuraminsäure und deren Salze enthaltende Expektorantien.

Info

Publication number
DE3587928T2
DE3587928T2 DE3587928T DE3587928T DE3587928T2 DE 3587928 T2 DE3587928 T2 DE 3587928T2 DE 3587928 T DE3587928 T DE 3587928T DE 3587928 T DE3587928 T DE 3587928T DE 3587928 T2 DE3587928 T2 DE 3587928T2
Authority
DE
Germany
Prior art keywords
expectorants
salts
acetylneuraminic acid
expectorant
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3587928T
Other languages
English (en)
Other versions
DE3587928D1 (de
Inventor
Sadanori Ogasawara
Takashi Hanafusa
Katsuhide Kariya
Masayoshi Ito
Yoshiyasu Shitori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Original Assignee
KANTO ISHI PHARMA CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd filed Critical KANTO ISHI PHARMA CO Ltd
Application granted granted Critical
Publication of DE3587928D1 publication Critical patent/DE3587928D1/de
Publication of DE3587928T2 publication Critical patent/DE3587928T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE3587928T 1984-09-11 1985-09-10 N-Acetylneuraminsäure und deren Salze enthaltende Expektorantien. Expired - Fee Related DE3587928T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59189950A JPS6168418A (ja) 1984-09-11 1984-09-11 去痰薬

Publications (2)

Publication Number Publication Date
DE3587928D1 DE3587928D1 (de) 1994-10-27
DE3587928T2 true DE3587928T2 (de) 1995-01-26

Family

ID=16249907

Family Applications (2)

Application Number Title Priority Date Filing Date
DE91100080T Expired - Fee Related DE3587587T2 (de) 1984-09-11 1985-09-10 N-Acetylneuraminsäure enthaltende Expektorantien.
DE3587928T Expired - Fee Related DE3587928T2 (de) 1984-09-11 1985-09-10 N-Acetylneuraminsäure und deren Salze enthaltende Expektorantien.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE91100080T Expired - Fee Related DE3587587T2 (de) 1984-09-11 1985-09-10 N-Acetylneuraminsäure enthaltende Expektorantien.

Country Status (14)

Country Link
US (1) US4698332A (de)
EP (2) EP0429430B1 (de)
JP (1) JPS6168418A (de)
KR (1) KR880001234B1 (de)
CN (1) CN85108388B (de)
AT (2) ATE94396T1 (de)
AU (1) AU582584B2 (de)
CA (1) CA1246452A (de)
DE (2) DE3587587T2 (de)
DK (1) DK165046C (de)
ES (1) ES8606323A1 (de)
FI (1) FI83963C (de)
HU (2) HU197515B (de)
ZA (1) ZA856905B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61289037A (ja) * 1985-06-14 1986-12-19 Mect Corp 新規去痰薬
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
JPH0530649Y2 (de) * 1986-08-28 1993-08-05
JP2573594B2 (ja) * 1987-03-06 1997-01-22 メクト株式会社 Nーアセチルー3ーフルオローノイラミン酸誘導体およびその製造方法
US5843445A (en) * 1987-06-24 1998-12-01 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
JP2517293B2 (ja) * 1987-06-25 1996-07-24 メクト株式会社 細胞、組織修復剤
US5393742A (en) * 1990-08-30 1995-02-28 Mect Corporation Preparation for treating renal disease
US5514665A (en) * 1993-12-30 1996-05-07 University Of British Columbia Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
AUPQ275799A0 (en) 1999-09-10 1999-10-07 Luminis Pty Limited Recombinant bacterium expressing an oligosaccharide receptor mimic
JP4005115B1 (ja) 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US9241896B2 (en) * 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
UA110325C2 (en) * 2009-07-03 2015-12-25 Australian Biomedical Company Pty Ltd Medicinal carbohydrates for treating respiratory conditions
EP2593109A4 (de) 2010-07-13 2014-01-08 Ultragenyx Pharmaceutical Inc Verfahren und formulierungen zur behandlung von sialinsäuremangel
WO2013063149A1 (en) 2011-10-24 2013-05-02 Ultragenyx Pharmaceutical, Inc. Sialic acid analogs
US11246878B2 (en) * 2013-03-15 2022-02-15 B&H Biotechnologies, Llc Compositions and products for infectious or inflammatory diseases or conditions
WO2014151526A1 (en) 2013-03-15 2014-09-25 Huiru Wang Biological therapeutics for infection-relating disorders or conditions
WO2016017677A1 (ja) * 2014-07-30 2016-02-04 協和発酵バイオ株式会社 N-アセチルノイラミン酸アルカリ金属塩・無水和物の結晶及びその製造方法
WO2016121810A1 (ja) * 2015-01-28 2016-08-04 協和発酵バイオ株式会社 N-アセチルノイラミン酸アンモニウム塩・無水和物の結晶及びその製造方法
WO2017048817A1 (en) 2015-09-14 2017-03-23 Ultragenyx Pharmaceutical Inc. Crystal forms of sialic acid or salt or solvate thereof
CN109771316B (zh) * 2018-12-29 2022-02-25 中国科学院合肥物质科学研究院 一种提高n-乙酰神经氨酸水溶液稳定性的方法及其应用
CN110606864B (zh) * 2019-10-08 2023-10-10 中国科学院合肥物质科学研究院 一种n-乙酰神经氨酸钙盐晶体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Also Published As

Publication number Publication date
ATE111738T1 (de) 1994-10-15
ATE94396T1 (de) 1993-10-15
EP0429430A3 (en) 1991-10-23
DE3587587T2 (de) 1994-03-31
FI853456L (fi) 1986-03-12
FI83963C (fi) 1991-09-25
CA1246452A (en) 1988-12-13
DE3587587D1 (de) 1993-10-21
CN85108388B (zh) 1988-08-24
EP0177783A2 (de) 1986-04-16
DE3587928D1 (de) 1994-10-27
JPS6168418A (ja) 1986-04-08
DK413785D0 (da) 1985-09-11
FI83963B (fi) 1991-06-14
KR860002525A (ko) 1986-04-26
FI853456A0 (fi) 1985-09-10
CN85108388A (zh) 1987-06-03
AU4719985A (en) 1986-03-20
ES8606323A1 (es) 1986-04-16
KR880001234B1 (ko) 1988-07-12
DK413785A (da) 1986-03-12
EP0177783B1 (de) 1994-09-21
HU197515B (en) 1989-04-28
HUT40804A (en) 1987-02-27
DK165046B (da) 1992-10-05
ES546840A0 (es) 1986-04-16
EP0177783A3 (en) 1989-02-22
JPS6328411B2 (de) 1988-06-08
HU198733B (en) 1989-11-28
EP0429430A2 (de) 1991-05-29
EP0429430B1 (de) 1993-09-15
US4698332A (en) 1987-10-06
ZA856905B (en) 1986-06-25
DK165046C (da) 1993-02-22
AU582584B2 (en) 1989-04-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee