KR860001547B1 - d-2-(6-메톡시-2-나프틸)-프로피온산의 제조방법 - Google Patents

d-2-(6-메톡시-2-나프틸)-프로피온산의 제조방법 Download PDF

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Publication number
KR860001547B1
KR860001547B1 KR8201353A KR820001353A KR860001547B1 KR 860001547 B1 KR860001547 B1 KR 860001547B1 KR 8201353 A KR8201353 A KR 8201353A KR 820001353 A KR820001353 A KR 820001353A KR 860001547 B1 KR860001547 B1 KR 860001547B1
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KR
South Korea
Prior art keywords
methoxy
naphthyl
propionic acid
mixture
bromo
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Expired
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KR8201353A
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English (en)
Korean (ko)
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KR830008973A (ko
Inventor
깐나따 빈첸쪼
따메트라니 쥐안까르로
Original Assignee
마리오 디 마르코
알파 케미칼스 이탈리아나 에스. 피. 에이
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR8201353A 1981-04-01 1982-03-29 d-2-(6-메톡시-2-나프틸)-프로피온산의 제조방법 Expired KR860001547B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
IT3385A/81 1981-04-01

Publications (2)

Publication Number Publication Date
KR830008973A KR830008973A (ko) 1983-12-16
KR860001547B1 true KR860001547B1 (ko) 1986-10-04

Family

ID=11106122

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8201353A Expired KR860001547B1 (ko) 1981-04-01 1982-03-29 d-2-(6-메톡시-2-나프틸)-프로피온산의 제조방법

Country Status (26)

Country Link
US (1) US4423244A (https=)
JP (1) JPS57176925A (https=)
KR (1) KR860001547B1 (https=)
AR (1) AR230614A1 (https=)
AT (1) AT390253B (https=)
BE (1) BE892689A (https=)
CA (1) CA1190939A (https=)
CH (1) CH651289A5 (https=)
DE (1) DE3212170A1 (https=)
DK (2) DK157076C (https=)
ES (1) ES510931A0 (https=)
FI (1) FI78455C (https=)
FR (1) FR2504918B1 (https=)
GB (1) GB2098981B (https=)
GR (1) GR76062B (https=)
HU (1) HU186852B (https=)
IE (1) IE52378B1 (https=)
IL (1) IL65298A (https=)
IT (1) IT1168387B (https=)
LU (1) LU84044A1 (https=)
NL (1) NL8201307A (https=)
NO (1) NO157733B (https=)
PT (1) PT74677B (https=)
SE (2) SE453492C (https=)
YU (1) YU42606B (https=)
ZA (1) ZA822145B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL141326B1 (en) * 1982-05-27 1987-07-31 Syntex Pharma Int Method of obtaining /d/-2-/6-metoxy-2-naphtyl/-propionic acid or its pharmacologically admissible salts
FI831820L (fi) * 1982-05-27 1983-11-28 Syntex Pharma Int Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4814497A (en) * 1986-05-12 1989-03-21 Ethyl Corporation Dehalogenation process
IT1238008B (it) * 1990-02-08 1993-06-21 Alfa Wassermann Spa Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni
FR2686877B1 (fr) * 1992-01-31 1995-03-24 Hoechst France Procede de preparation de l'acide orthohydroxyphenylacetique.
JPH0646907U (ja) * 1992-12-10 1994-06-28 リョービ株式会社 すべり勾配面加工用治具
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
CA936171A (en) * 1970-09-09 1973-10-30 Syntex Corporation Process for preparing 2-(6-methoxy-2-naphthyl) propionic acid and 2-(6-methoxy-2-naphthyl)-1-propanol
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Also Published As

Publication number Publication date
ATA127082A (de) 1989-09-15
FI78455C (fi) 1989-08-10
DE3212170C2 (https=) 1989-03-02
NL8201307A (nl) 1982-11-01
KR830008973A (ko) 1983-12-16
YU42606B (en) 1988-10-31
DK147482A (da) 1982-10-02
DK157076C (da) 1990-04-09
FI821121A0 (fi) 1982-03-31
CA1190939A (en) 1985-07-23
PT74677B (en) 1983-10-31
US4423244B1 (https=) 1987-07-28
IL65298A0 (en) 1982-05-31
DK256589D0 (da) 1989-05-26
NO157733B (no) 1988-02-01
NO821088L (no) 1982-10-04
US4423244A (en) 1983-12-27
SE453492C (sv) 1994-10-03
SE8501744L (sv) 1985-04-09
YU72082A (en) 1985-03-20
DK157076B (da) 1989-11-06
SE8501744D0 (sv) 1985-04-09
IT8103385A0 (it) 1981-04-01
GR76062B (https=) 1984-08-03
FI78455B (fi) 1989-04-28
GB2098981B (en) 1984-10-24
AR230614A1 (es) 1984-05-31
ZA822145B (en) 1983-02-23
PT74677A (en) 1982-04-01
DE3212170A1 (de) 1982-10-21
HU186852B (en) 1985-10-28
IT1168387B (it) 1987-05-20
FI821121L (fi) 1982-10-02
SE453492B (sv) 1988-02-08
JPS57176925A (en) 1982-10-30
GB2098981A (en) 1982-12-01
IE52378B1 (en) 1987-09-30
FR2504918B1 (fr) 1985-06-14
AT390253B (de) 1990-04-10
SE466199B (sv) 1992-01-13
DK256589A (da) 1989-05-26
IL65298A (en) 1985-02-28
JPH0231704B2 (https=) 1990-07-16
ES8302622A1 (es) 1983-02-01
IE820770L (en) 1982-10-01
SE8202050L (sv) 1982-10-02
BE892689A (fr) 1982-09-30
CH651289A5 (de) 1985-09-13
ES510931A0 (es) 1983-02-01
FR2504918A1 (fr) 1982-11-05
LU84044A1 (fr) 1983-02-22

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