KR20230100748A - 키메라 항원 수용체 및 pd-1 억제제의 조합 요법 - Google Patents

키메라 항원 수용체 및 pd-1 억제제의 조합 요법 Download PDF

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Publication number
KR20230100748A
KR20230100748A KR1020237020747A KR20237020747A KR20230100748A KR 20230100748 A KR20230100748 A KR 20230100748A KR 1020237020747 A KR1020237020747 A KR 1020237020747A KR 20237020747 A KR20237020747 A KR 20237020747A KR 20230100748 A KR20230100748 A KR 20230100748A
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seq
car
amino acid
days
acid sequence
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KR1020237020747A
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Korean (ko)
Inventor
외즐렘 아나크
사넬라 빌릭
제니퍼 브로그돈
존 스콧 카메론
윌리엄 초우
대니 롤랜드 주니어 하워드
란디 이삭스
카를 에이치. 준
사이먼 레이시
섀넌 모드
잔 제이. 멜렌호스트
스테판 슈스터
알폰소 퀸타스-카르다마
스테판 그루프
한스 비터
Original Assignee
노파르티스 아게
더 트러스티스 오브 더 유니버시티 오브 펜실바니아
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Application filed by 노파르티스 아게, 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 filed Critical 노파르티스 아게
Priority to KR1020257012937A priority Critical patent/KR20250061769A/ko
Publication of KR20230100748A publication Critical patent/KR20230100748A/ko
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KR1020237020747A 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법 Ceased KR20230100748A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257012937A KR20250061769A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201662368100P 2016-07-28 2016-07-28
US62/368,100 2016-07-28
US201762455547P 2017-02-06 2017-02-06
US62/455,547 2017-02-06
US201762482846P 2017-04-07 2017-04-07
US62/482,846 2017-04-07
US201762514542P 2017-06-02 2017-06-02
US62/514,542 2017-06-02
KR1020197005490A KR20190034588A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법
PCT/US2017/044425 WO2018023025A1 (en) 2016-07-28 2017-07-28 Combination therapies of chimeric antigen receptors adn pd-1 inhibitors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197005490A Division KR20190034588A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법

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Application Number Title Priority Date Filing Date
KR1020257012937A Division KR20250061769A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법

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KR20230100748A true KR20230100748A (ko) 2023-07-05

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Application Number Title Priority Date Filing Date
KR1020237020747A Ceased KR20230100748A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법
KR1020257012937A Pending KR20250061769A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법
KR1020197005490A Ceased KR20190034588A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법

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KR1020257012937A Pending KR20250061769A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법
KR1020197005490A Ceased KR20190034588A (ko) 2016-07-28 2017-07-28 키메라 항원 수용체 및 pd-1 억제제의 조합 요법

Country Status (13)

Country Link
US (1) US20190151365A1 (https=)
EP (1) EP3491016A1 (https=)
JP (3) JP2019523301A (https=)
KR (3) KR20230100748A (https=)
CN (3) CN117959417A (https=)
AU (2) AU2017302668B9 (https=)
BR (1) BR112019001570A2 (https=)
CA (1) CA3032054A1 (https=)
IL (2) IL316970A (https=)
MY (1) MY205684A (https=)
SG (1) SG11201900677SA (https=)
TW (2) TW202508628A (https=)
WO (1) WO2018023025A1 (https=)

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JP6647868B2 (ja) 2013-02-20 2020-02-14 ノバルティス アーゲー ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置
US9573988B2 (en) 2013-02-20 2017-02-21 Novartis Ag Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
WO2014145252A2 (en) 2013-03-15 2014-09-18 Milone Michael C Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
WO2015112626A1 (en) 2014-01-21 2015-07-30 June Carl H Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
PE20170255A1 (es) 2014-01-24 2017-03-22 Dana Farber Cancer Inst Inc Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
KR102442436B1 (ko) * 2014-03-14 2022-09-15 노파르티스 아게 Lag-3에 대한 항체 분자 및 그의 용도
US20170335281A1 (en) * 2014-03-15 2017-11-23 Novartis Ag Treatment of cancer using chimeric antigen receptor
BR112017001183A2 (pt) 2014-07-21 2017-11-28 Novartis Ag tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
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