KR20220038362A - 재조합 ad35 벡터 및 관련 유전자 요법 개선 - Google Patents

재조합 ad35 벡터 및 관련 유전자 요법 개선 Download PDF

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KR20220038362A
KR20220038362A KR1020227003415A KR20227003415A KR20220038362A KR 20220038362 A KR20220038362 A KR 20220038362A KR 1020227003415 A KR1020227003415 A KR 1020227003415A KR 20227003415 A KR20227003415 A KR 20227003415A KR 20220038362 A KR20220038362 A KR 20220038362A
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vector
genome
helper
nucleic acid
globin
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Korean (ko)
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한스-피터 키엠
안드레 리버
창 리
홍지에 왕
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프레드 헛친슨 켄서 리서치 센터
유니버시티 오브 워싱톤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/14—Hydrolases (3)
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
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    • C12N2800/50—Vectors for producing vectors
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
    • C12N2810/6018—Adenoviridae
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    • C12N2999/00—Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
    • C12N2999/007—Technological advancements, e.g. new system for producing known virus, cre-lox system for production of transgenic animals

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  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020227003415A 2019-07-02 2020-07-02 재조합 ad35 벡터 및 관련 유전자 요법 개선 Pending KR20220038362A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962869907P 2019-07-02 2019-07-02
US62/869,907 2019-07-02
US201962935507P 2019-11-14 2019-11-14
US62/935,507 2019-11-14
US202063009385P 2020-04-13 2020-04-13
US63/009,385 2020-04-13
PCT/US2020/040756 WO2021003432A1 (en) 2019-07-02 2020-07-02 Recombinant ad35 vectors and related gene therapy improvements

Publications (1)

Publication Number Publication Date
KR20220038362A true KR20220038362A (ko) 2022-03-28

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KR1020227003415A Pending KR20220038362A (ko) 2019-07-02 2020-07-02 재조합 ad35 벡터 및 관련 유전자 요법 개선

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US (1) US20220257796A1 (https=)
EP (1) EP3994270A1 (https=)
JP (1) JP2022539248A (https=)
KR (1) KR20220038362A (https=)
CN (1) CN114729383A (https=)
AU (1) AU2020298572A1 (https=)
BR (1) BR112021026832A2 (https=)
CA (1) CA3138188A1 (https=)
IL (1) IL289518A (https=)
MX (1) MX2021015433A (https=)
SG (1) SG11202111943UA (https=)
WO (1) WO2021003432A1 (https=)

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T11 Administrative time limit extension requested

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T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000