KR20210070232A - 크로몰린 나트륨 및 이부프로펜의 분말화된 제형 - Google Patents
크로몰린 나트륨 및 이부프로펜의 분말화된 제형 Download PDFInfo
- Publication number
- KR20210070232A KR20210070232A KR1020207004292A KR20207004292A KR20210070232A KR 20210070232 A KR20210070232 A KR 20210070232A KR 1020207004292 A KR1020207004292 A KR 1020207004292A KR 20207004292 A KR20207004292 A KR 20207004292A KR 20210070232 A KR20210070232 A KR 20210070232A
- Authority
- KR
- South Korea
- Prior art keywords
- ibuprofen
- sodium
- cromolin
- sieve
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762534848P | 2017-07-20 | 2017-07-20 | |
| US62/534,848 | 2017-07-20 | ||
| PCT/US2017/065727 WO2019017995A1 (en) | 2017-07-20 | 2017-12-12 | FORMULATIONS OF CROMOLYNE SODIUM POWDER AND IBUPROFEN |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210070232A true KR20210070232A (ko) | 2021-06-14 |
Family
ID=65014583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207004292A Ceased KR20210070232A (ko) | 2017-07-20 | 2017-12-12 | 크로몰린 나트륨 및 이부프로펜의 분말화된 제형 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10561612B2 (https=) |
| EP (1) | EP3654946A4 (https=) |
| JP (1) | JP7202376B2 (https=) |
| KR (1) | KR20210070232A (https=) |
| CN (1) | CN111565711B (https=) |
| AU (1) | AU2017423862A1 (https=) |
| CA (1) | CA3070386A1 (https=) |
| MX (1) | MX2020000577A (https=) |
| WO (1) | WO2019017995A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| EP3563849A3 (en) | 2012-10-25 | 2020-02-12 | The General Hospital Corporation | Combination therapies for the treatment of alzheimer's disease and related disorders |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| CN110305095A (zh) | 2013-10-22 | 2019-10-08 | 综合医院公司 | 色甘酸衍生物以及成像和治疗的相关方法 |
| JP2019524865A (ja) | 2016-08-31 | 2019-09-05 | ザ ジェネラル ホスピタル コーポレイション | 神経変性疾患と関連する神経炎症におけるマクロファージ/ミクログリア |
| AU2019299347A1 (en) | 2018-07-02 | 2021-01-21 | Aztherapies, Inc. | Powdered formulations of cromolyn sodium and alpha-lactose |
| MX2021006869A (es) | 2018-12-10 | 2021-07-02 | Massachusetts Gen Hospital | Esteres de cromolin y usos de los mismos. |
| WO2021207060A1 (en) | 2020-04-06 | 2021-10-14 | The General Hospital Corporation | Methods of treatment of coronavirus-induced inflammation conditions |
| WO2022146914A1 (en) | 2020-12-28 | 2022-07-07 | The General Hospital Corporation | Cromolyn derivatives and uses thereof |
Family Cites Families (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1144905A (en) | 1965-03-25 | 1969-03-12 | Fisons Pharmaceuticals Ltd | Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof |
| US3686412A (en) | 1965-03-25 | 1972-08-22 | Colin Fitzmaurice | Compositions containing bis-chromonyl compounds for inhibiting antigen-antibody reactions |
| US3957965A (en) | 1967-08-08 | 1976-05-18 | Fisons Limited | Sodium chromoglycate inhalation medicament |
| GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
| GB1257162A (https=) | 1968-02-16 | 1971-12-15 | ||
| US4120285A (en) | 1976-11-01 | 1978-10-17 | Owens-Illinois, Inc. | Modular tubular solar energy collector apparatus |
| DE3104294A1 (de) | 1981-02-07 | 1982-08-19 | Hoechst Ag, 6000 Frankfurt | Substituierte diazaspirodecane, ihre herstellung, ihre verwendung als stabilisatoren fuer organische polymere, sowie die so stabilisierten polymeren |
| US4429545A (en) | 1981-08-03 | 1984-02-07 | Ocean & Atmospheric Science, Inc. | Solar heating system |
| BE897058A (fr) | 1982-06-25 | 1983-12-16 | Sandoz Sa | Utilisation d'un derive du spiro-succinimide dans le traitement de la demence du type alzheimer |
| US4996296A (en) | 1983-07-27 | 1991-02-26 | Yeda Research & Development Co., Ltd. | Cromolyn binding protein in highly purifed form, and methods for the isolation thereof |
| US4919915A (en) | 1987-03-03 | 1990-04-24 | Paul Averback | Method for detecting the ability to prevent red-to-green congophilic birefringence |
| US5231170A (en) | 1986-08-27 | 1993-07-27 | Paul Averback | Antibodies to dense microspheres |
| CA2058764A1 (en) | 1989-04-28 | 1990-10-29 | Peter D. Hodson | Dry powder inhalation device |
| DE4405387A1 (de) | 1994-02-19 | 1995-08-24 | Hoechst Ag | Verfahren zur Herstellung von Polyalkyl-1-oxa-diazaspirodecan-Verbindungen |
| US6168776B1 (en) | 1994-07-19 | 2001-01-02 | University Of Pittsburgh | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| TR199600329A2 (tr) | 1995-05-05 | 1997-03-21 | Hoffmann La Roche | Seker alkollerin yeni sülfürik asit esterleri. |
| US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| AU756693B2 (en) | 1997-09-29 | 2003-01-23 | Novartis Ag | Stabilized bioactive preparations and methods of use |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US5904937A (en) | 1997-10-03 | 1999-05-18 | Fmc Corporation | Taste masked pharmaceutical compositions |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US6197963B1 (en) | 1998-08-13 | 2001-03-06 | The Trustees Of The University Of Pennsylvania | Non-peptide peptidomimetics |
| US6458338B1 (en) * | 1998-09-22 | 2002-10-01 | Aeropharm Technology Incorporated | Amino acid stabilized medicinal aerosol formulations |
| AU775914B2 (en) | 1998-12-24 | 2004-08-19 | Janssen Pharmaceutica N.V. | Controlled release galantamine composition |
| JP2001151673A (ja) | 1999-09-06 | 2001-06-05 | Nikken Chem Co Ltd | 吸入用粉末製剤の製造方法 |
| US20020107173A1 (en) | 1999-11-04 | 2002-08-08 | Lawrence Friedhoff | Method of treating amyloid beta precursor disorders |
| US20020009491A1 (en) | 2000-02-14 | 2002-01-24 | Rothbard Jonathan B. | Compositions and methods for enhancing drug delivery across biological membranes and tissues |
| JP5025871B2 (ja) | 2000-02-21 | 2012-09-12 | エイチ.リュンドベック エイ/エス | アミロイドの新規なダウン−レギュレート方法 |
| US20080021085A1 (en) | 2000-04-13 | 2008-01-24 | Mayo Foundation For Medical Education And Research | Method of reducing abeta42 and treating diseases |
| JP2003530437A (ja) | 2000-04-13 | 2003-10-14 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | Aβ42低下物質 |
| MY120279A (en) | 2000-05-26 | 2005-09-30 | Pharmacia Corp | Use of a celecoxib composition for fast pain relief |
| US20020016359A1 (en) | 2000-06-29 | 2002-02-07 | Hellberg Mark R. | Compositions and methods of treating neurodegenerative diseases |
| US8519005B2 (en) | 2000-07-27 | 2013-08-27 | Thomas N. Thomas | Compositions and methods to prevent toxicity of antiinflammatory agents and enhance their efficacy |
| FR2815030A1 (fr) | 2000-10-05 | 2002-04-12 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant et leur utilisation pour la preparation de medicaments |
| US6511960B2 (en) | 2001-01-05 | 2003-01-28 | Alphamed Pharmaceuticals Corp | Cromolyn for eye and ear infections |
| CA2444214A1 (en) | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| CA2466863A1 (en) | 2001-11-29 | 2003-06-05 | Emisphere Technologies, Inc. | Oral pharmaceutical compositions comprising cromolyn sodium and an acylated amino acid |
| EP1601380A1 (en) | 2003-02-13 | 2005-12-07 | Licentia OY | Use of a mast cell activation or degranulation blocking agent in the manufacture of a medicament for the treatment of cerebral ischemia |
| JP2006522634A (ja) * | 2003-04-14 | 2006-10-05 | ベクトゥラ・リミテッド | 投与効率を向上させるデバイス及び製薬組成 |
| US20040223918A1 (en) | 2003-05-07 | 2004-11-11 | Chrysalis Technologies Incorporated | Aerosolization of cromolyn sodium using a capillary aerosol generator |
| GB0321607D0 (en) | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
| JP4471340B2 (ja) | 2003-10-07 | 2010-06-02 | 芦森工業株式会社 | バックル装置 |
| DE10355559A1 (de) | 2003-11-21 | 2005-06-23 | Orthogen Ag | Transskin |
| US8088935B2 (en) | 2003-12-23 | 2012-01-03 | Ironwood Pharmaceuticals, Inc. | Compounds and methods for the treatment of asthma |
| WO2005077394A1 (en) | 2004-02-11 | 2005-08-25 | Ramot At Tel-Aviv University Ltd | Compositions for treatment of cancer and inflammation with curcumin and at least one nsaid |
| WO2006001877A2 (en) | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| CN101098678A (zh) | 2004-04-23 | 2008-01-02 | 锡德克斯公司 | 含有磺基烷基醚环糊精的dpi制剂 |
| DE602005019582D1 (de) | 2004-08-30 | 2010-04-08 | Seo Hong Yoo | Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell |
| ZA200708857B (en) | 2005-04-22 | 2009-01-28 | Genentech Inc | Method for treating dementia or alzheimer's disease with a CD30 antibody |
| CA2609980C (en) | 2005-05-27 | 2015-10-13 | Queen's University At Kingston | Treatment of protein folding disorders |
| CA2631493A1 (en) | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
| US8263645B2 (en) | 2006-02-03 | 2012-09-11 | Pari Pharma Gmbh | Disodium cromoglycate compositions and methods for administering same |
| AR059356A1 (es) | 2006-02-14 | 2008-03-26 | Astrazeneca Ab | Nuevos radioligandos |
| DE602007009807D1 (de) | 2006-03-06 | 2010-11-25 | Raqualia Pharma Inc | Sulfonylbenzimidazolderivate |
| CN103054837A (zh) | 2006-03-09 | 2013-04-24 | 瓦拉塔药品公司 | 用于治疗蛋白积聚病症的环己烷多元醇制剂 |
| WO2008118122A2 (en) | 2006-05-08 | 2008-10-02 | Molecular Neuroimaging, Llc | Compounds and amyloid probes thereof for therapeutic and imaging uses |
| US8445437B2 (en) | 2006-07-27 | 2013-05-21 | The Brigham And Women's Hospital, Inc. | Treatment and prevention of cardiovascular disease using mast cell stabilizers |
| US20100173960A1 (en) | 2006-09-21 | 2010-07-08 | Antonio Cruz | The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases |
| WO2008061373A1 (en) | 2006-11-24 | 2008-05-29 | Waratah Pharmaceuticals Inc. | Combination treatments for alzheimer's disease and similar diseases |
| US20080292625A1 (en) | 2007-04-18 | 2008-11-27 | Sally Schroeter | Prevention and treatment of cerebral amyloid angiopathy |
| ES2468551T3 (es) | 2007-04-18 | 2014-06-16 | Probiodrug Ag | Derivados de nitrovinil-diamina como inhibidores de la glutaminil ciclasa |
| US7858803B2 (en) | 2007-04-27 | 2010-12-28 | The General Hospital Corporation | Imaging tracers for early detection and treatment of amyloid plaques caused by Alzheimer's disease and related disorders |
| JP2010533181A (ja) | 2007-07-13 | 2010-10-21 | アボツト・バイオテクノロジー・リミテツド | TNFα阻害剤の肺投与のための方法及び組成物 |
| GB0714134D0 (en) | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
| DK2182983T3 (da) | 2007-07-27 | 2014-07-14 | Janssen Alzheimer Immunotherap | Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| EP3231804B1 (en) | 2008-03-21 | 2021-03-03 | The General Hospital Corporation | Compounds and compositions for the detection and treatment of alzheimer's disease and related disorders |
| WO2009133128A1 (en) | 2008-04-29 | 2009-11-05 | Pharnext | Combination compositions for treating alzheimer disease and related disorders with zonisamide and acamprosate |
| CA2747801A1 (en) | 2009-01-22 | 2010-07-29 | Raqualia Pharma Inc. | N-substituted saturated heterocyclic sulfone compounds with cb2 receptor agonistic activity |
| US8381454B1 (en) | 2009-01-23 | 2013-02-26 | Markus R. Robinson | Segmented, elongated, expandable, 4-season, double-walled, low-cost, rigid extruded plastic panel structures |
| US8617517B2 (en) | 2009-01-29 | 2013-12-31 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| TWI541021B (zh) | 2009-03-05 | 2016-07-11 | 艾伯維有限公司 | Il-17結合蛋白 |
| AU2010224184A1 (en) | 2009-03-11 | 2011-09-29 | Plexxikon, Inc. | Pyrrolo [2, 3-b] pyridine derivatives for the inhibition of Raf kinases |
| WO2010107702A1 (en) | 2009-03-16 | 2010-09-23 | Ipintl, Llc | Treating alzheimer's disease and osteoporosis and reducing aging |
| PL2248517T3 (pl) | 2009-05-08 | 2014-08-29 | Pari Pharma Gmbh | Stężone formulacje farmaceutyczne stabilizujące komórki tuczne |
| BR112012002333A2 (pt) | 2009-08-06 | 2017-07-18 | Neuraltus Pharmaceuticals Inc | método de reduzir os efeitos colaterais e método de potencializar o efeito de um imunomodulador administrado a um sujeito que dele necessita; métodos para tratar doença associada com excesso de ativação de monócitos para macrófagos ativados, diabetes tipo ii ou complicações relacionadas, doença associada com a migração de monócitos ou macrófagos ativados, doença associada a excesso de produção de scd14 e/ou scd163 por macrófagos ativados; composto de cloreto de sódio; composição farmacêutica; método para diagnosticar uma doença relacionada com macrófagos em um sujeito; e método para determinar a eficácia do tratamento com um agente oxidante para uma doença relacionada a macrófagos em um sujeito. |
| WO2011032164A2 (en) | 2009-09-14 | 2011-03-17 | Kmetovicz Ronald E | Solar heat pipe heat exchanger |
| MX355627B (es) | 2009-09-24 | 2018-04-25 | Wista Lab Ltd | Clorhidratos de metiltioninio (azul de metileno) cristalinos. |
| EP2322163A1 (en) | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| WO2011057199A1 (en) | 2009-11-06 | 2011-05-12 | Adenios, Inc. | Compositions for treating cns disorders |
| MX337603B (es) * | 2009-11-30 | 2016-03-10 | Adare Pharmaceuticals Inc | Composiciones y tabletas farmaceuticas con recubrimiento compresible y metodos de fabricacion. |
| US8455755B2 (en) | 2009-12-07 | 2013-06-04 | Electrotherm | Concentrated photovoltaic and thermal solar energy collector |
| EP2377860A1 (en) | 2010-04-16 | 2011-10-19 | AC Immune S.A. | Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins |
| WO2011136754A1 (en) | 2010-04-26 | 2011-11-03 | Mahmut Bilgic | A medicament developed for the treatment of respiratory diseases |
| RU2580890C2 (ru) | 2010-09-30 | 2016-04-10 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Применение стеарата магния в составах сухого порошка для ингаляции |
| US20120121656A1 (en) | 2010-11-15 | 2012-05-17 | Revalesio Corporation | Methods and compositions for protecting against neurotoxicity of a neurotoxic agent, and improving motor coordination associated with a neurodegenerative condition or disease |
| JP5898701B2 (ja) | 2011-02-11 | 2016-04-13 | ウィスタ ラボラトリーズ リミテッド | フェノチアジンジアミニウム塩およびそれらの使用 |
| JP2015518006A (ja) | 2012-05-25 | 2015-06-25 | エクスクリア インコーポレイテッド | キシリトール系の抗粘膜組成物及び関連する方法並びに組成物 |
| EP3563849A3 (en) | 2012-10-25 | 2020-02-12 | The General Hospital Corporation | Combination therapies for the treatment of alzheimer's disease and related disorders |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| WO2015002703A1 (en) | 2013-05-23 | 2015-01-08 | Aztherapies, Inc | Methods for delivering cromolyn |
| CN110305095A (zh) | 2013-10-22 | 2019-10-08 | 综合医院公司 | 色甘酸衍生物以及成像和治疗的相关方法 |
| ES2792682T3 (es) | 2014-02-10 | 2020-11-11 | Respivant Sciences Gmbh | Métodos para el tratamiento de enfermedades pulmonares con estabilizadores de mastocitos |
| PL3104853T3 (pl) | 2014-02-10 | 2020-05-18 | Respivant Sciences Gmbh | Leczenie stabilizatorami komórek tucznych zaburzeń ogólnoustrojowych |
| US11723864B2 (en) * | 2015-05-29 | 2023-08-15 | The Texas A&M University System | Antimicrobial and anti-inflammatory compositions |
| MX2018006247A (es) * | 2015-11-19 | 2018-11-29 | Aztherapies Inc | Metodos para tratar la enfermedad de alzheimer y trastornos relacionados. |
| US20180344682A1 (en) | 2015-11-23 | 2018-12-06 | Aztherapies, Inc. | Compositions and methods for treating ischemic stroke |
| JP2019524865A (ja) | 2016-08-31 | 2019-09-05 | ザ ジェネラル ホスピタル コーポレイション | 神経変性疾患と関連する神経炎症におけるマクロファージ/ミクログリア |
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2017
- 2017-12-12 JP JP2020524710A patent/JP7202376B2/ja active Active
- 2017-12-12 CA CA3070386A patent/CA3070386A1/en active Pending
- 2017-12-12 US US15/838,753 patent/US10561612B2/en active Active
- 2017-12-12 WO PCT/US2017/065727 patent/WO2019017995A1/en not_active Ceased
- 2017-12-12 AU AU2017423862A patent/AU2017423862A1/en not_active Abandoned
- 2017-12-12 KR KR1020207004292A patent/KR20210070232A/ko not_active Ceased
- 2017-12-12 MX MX2020000577A patent/MX2020000577A/es unknown
- 2017-12-12 CN CN201780093378.2A patent/CN111565711B/zh not_active Expired - Fee Related
- 2017-12-12 EP EP17918310.8A patent/EP3654946A4/en not_active Withdrawn
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2020
- 2020-02-13 US US16/789,775 patent/US20210023010A1/en not_active Abandoned
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2022
- 2022-09-07 US US17/939,396 patent/US20230248650A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019017995A1 (en) | 2019-01-24 |
| JP2020528453A (ja) | 2020-09-24 |
| JP7202376B2 (ja) | 2023-01-11 |
| MX2020000577A (es) | 2020-09-10 |
| US20190022006A1 (en) | 2019-01-24 |
| CA3070386A1 (en) | 2019-01-24 |
| AU2017423862A1 (en) | 2020-02-06 |
| CN111565711A (zh) | 2020-08-21 |
| EP3654946A1 (en) | 2020-05-27 |
| CN111565711B (zh) | 2023-01-03 |
| US10561612B2 (en) | 2020-02-18 |
| US20230248650A1 (en) | 2023-08-10 |
| EP3654946A4 (en) | 2021-04-21 |
| US20210023010A1 (en) | 2021-01-28 |
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