KR20180051626A - Kras 발현의 조절제 - Google Patents
Kras 발현의 조절제 Download PDFInfo
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- KR20180051626A KR20180051626A KR1020187010307A KR20187010307A KR20180051626A KR 20180051626 A KR20180051626 A KR 20180051626A KR 1020187010307 A KR1020187010307 A KR 1020187010307A KR 20187010307 A KR20187010307 A KR 20187010307A KR 20180051626 A KR20180051626 A KR 20180051626A
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| EA037928B1 (ru) | 2014-03-26 | 2021-06-08 | Ф. Хоффманн-Ля Рош Аг | Бициклические соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa) |
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| JP7090099B2 (ja) | 2017-03-16 | 2022-06-23 | エフ．ホフマン－ラ ロシュ アーゲー | Ａｔｘインヒビターとしての新規二環式化合物 |
| BR112019019017A2 (pt) | 2017-03-16 | 2020-04-14 | Hoffmann La Roche | compostos heterocíclicos de utilidade como inibidores duplos de atx/ca |
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| TWI840345B (zh) * | 2018-03-02 | 2024-05-01 | 美商Ionis製藥公司 | Irf4表現之調節劑 |
| WO2019217307A1 (en) | 2018-05-07 | 2019-11-14 | Mirati Therapeutics, Inc. | Kras g12c inhibitors |
| JP7247227B2 (ja) * | 2018-05-22 | 2023-03-28 | アイオニス・ファーマシューティカルズ・インコーポレイテッド | Ａｐｏｌ１発現のモジュレーター |
| US11866705B2 (en) | 2018-07-31 | 2024-01-09 | Osaka Univerity | Small cell lung cancer therapeutic agent containing oligonucleotide |
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| CN110981943B (zh) * | 2019-12-02 | 2021-08-03 | 清华大学 | 多肽及其在制备药物中的用途和药物 |
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| JP7427227B2 (ja) * | 2020-01-21 | 2024-02-05 | 学校法人産業医科大学 | 腫瘍細胞の生存を低下させるｋｒａｓアンチセンスオリゴヌクレオチド及びその用途 |
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| WO2024155770A2 (en) * | 2023-01-18 | 2024-07-25 | Molecular Axiom, Llc | Compositions for modulating kras expression and uses thereof |
| CN119639745B (zh) * | 2024-12-12 | 2025-11-25 | 制能(北京)生物科技有限公司 | 一种靶向kras基因的反义核酸及其药物制剂和应用 |
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- 2016-09-23 JP JP2018515292A patent/JP6877414B2/ja not_active Expired - Fee Related
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| MX2018003472A (es) | 2018-07-06 |
| AR106135A1 (es) | 2017-12-13 |
| AU2016326619A1 (en) | 2018-05-10 |
| AU2020260436A1 (en) | 2020-11-26 |
| CN108513588A (zh) | 2018-09-07 |
| WO2017053722A1 (en) | 2017-03-30 |
| JP6877414B2 (ja) | 2021-05-26 |
| HK1255699A1 (zh) | 2019-08-23 |
| RU2018113709A3 (enExample) | 2020-05-29 |
| RU2018113709A (ru) | 2019-10-30 |
| IL258013A (en) | 2018-05-31 |
| CA2998382A1 (en) | 2017-03-30 |
| HK1251624A1 (zh) | 2019-02-01 |
| ZA201802663B (en) | 2019-01-30 |
| JP2018528781A (ja) | 2018-10-04 |
| CL2018000429A1 (es) | 2018-08-10 |
| CO2018003168A2 (es) | 2018-06-20 |
| BR112018004620A2 (pt) | 2018-09-25 |
| AU2016326619B2 (en) | 2020-07-30 |
| EP3353328A4 (en) | 2019-06-12 |
| US20180273577A1 (en) | 2018-09-27 |
| TW201723176A (zh) | 2017-07-01 |
| EP3353328A1 (en) | 2018-08-01 |
| SG10201913209WA (en) | 2020-02-27 |
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