KR20180050441A - 경피용 치료학적 시스템 - Google Patents

경피용 치료학적 시스템 Download PDF

Info

Publication number
KR20180050441A
KR20180050441A KR1020187012945A KR20187012945A KR20180050441A KR 20180050441 A KR20180050441 A KR 20180050441A KR 1020187012945 A KR1020187012945 A KR 1020187012945A KR 20187012945 A KR20187012945 A KR 20187012945A KR 20180050441 A KR20180050441 A KR 20180050441A
Authority
KR
South Korea
Prior art keywords
tts
active ingredient
ribastigmine
layer
preferred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020187012945A
Other languages
English (en)
Korean (ko)
Inventor
폴 엠. 자르지울로
로저 마이클 레인
베아트릭스 플라트
프랑크 테오발트
베티나 발
Original Assignee
노파르티스 아게
에르테에스 로만 테라피-시스테메 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37716856&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20180050441(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게, 에르테에스 로만 테라피-시스테메 아게 filed Critical 노파르티스 아게
Publication of KR20180050441A publication Critical patent/KR20180050441A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020187012945A 2005-12-01 2006-10-10 경피용 치료학적 시스템 Ceased KR20180050441A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74151105P 2005-12-01 2005-12-01
US60/741,511 2005-12-01
PCT/US2006/039557 WO2007064407A1 (en) 2005-12-01 2006-10-10 Transdermal therapeutic system

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020177006994A Division KR20170033449A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020217001087A Division KR20210008440A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템

Publications (1)

Publication Number Publication Date
KR20180050441A true KR20180050441A (ko) 2018-05-14

Family

ID=37716856

Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020187012945A Ceased KR20180050441A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020217001087A Ceased KR20210008440A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020177006994A Ceased KR20170033449A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020227039266A Ceased KR20220156666A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020147010333A Withdrawn KR20140072108A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020087013112A Ceased KR20080071581A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020137031255A Ceased KR20130143729A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템

Family Applications After (6)

Application Number Title Priority Date Filing Date
KR1020217001087A Ceased KR20210008440A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020177006994A Ceased KR20170033449A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020227039266A Ceased KR20220156666A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020147010333A Withdrawn KR20140072108A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020087013112A Ceased KR20080071581A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템
KR1020137031255A Ceased KR20130143729A (ko) 2005-12-01 2006-10-10 경피용 치료학적 시스템

Country Status (31)

Country Link
US (3) US20070128263A1 (enExample)
EP (5) EP1959937A1 (enExample)
JP (3) JP2009517468A (enExample)
KR (7) KR20180050441A (enExample)
CN (2) CN102048713A (enExample)
AR (2) AR057152A1 (enExample)
AT (1) AT11185U1 (enExample)
AU (1) AU2006320919B2 (enExample)
BR (2) BR122013013162A2 (enExample)
CA (1) CA2563110A1 (enExample)
DE (2) DE202006021172U1 (enExample)
DK (5) DK2292219T3 (enExample)
EC (1) ECSP088469A (enExample)
ES (1) ES2414455T3 (enExample)
FI (1) FI10268U1 (enExample)
GT (1) GT200800075A (enExample)
IL (4) IL191311A (enExample)
MA (1) MA30022B1 (enExample)
MY (2) MY151020A (enExample)
NO (1) NO20082753L (enExample)
NZ (1) NZ568273A (enExample)
PH (2) PH12013500772B1 (enExample)
PL (1) PL2292219T4 (enExample)
PT (1) PT2292219E (enExample)
RU (1) RU2450805C2 (enExample)
SG (1) SG2014014989A (enExample)
SI (1) SI2292219T1 (enExample)
TN (1) TNSN08238A1 (enExample)
TW (1) TWI389709B (enExample)
WO (1) WO2007064407A1 (enExample)
ZA (1) ZA200803882B (enExample)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
US9248104B2 (en) * 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
TWI630208B (zh) 2008-12-08 2018-07-21 歐陸斯迪公司 二氫羥戊甲嗎啡
GB0823554D0 (en) 2008-12-24 2009-01-28 Novartis Ag Process for the preparation of optically active compounds using transfer hydrogenation
EP2419485B1 (en) * 2009-04-17 2018-05-23 3M Innovative Properties Company Silicone gel adhesive construction
WO2010129689A1 (en) * 2009-05-05 2010-11-11 Forest Laboratories Holdings Limited Milnacipran formulations
EP2493457B1 (en) 2009-10-30 2017-08-09 IX Biopharma Ltd Fast dissolving solid dosage form
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
WO2011073362A1 (en) 2009-12-18 2011-06-23 Novartis Ag Process for the preparation of optically active compounds using pressure hydrogenation
US10076502B2 (en) 2009-12-22 2018-09-18 Luye Pharma Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US8962014B2 (en) * 2009-12-22 2015-02-24 Acino Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
DE102010024105A1 (de) * 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
RU2578971C2 (ru) * 2010-06-17 2016-03-27 Лтс Ломанн Терапи-Системе Аг Трансдермальное введение мемантина
DE102010026903A1 (de) 2010-07-12 2012-01-12 Amw Gmbh Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff
EP3517105B8 (en) 2010-07-21 2021-06-23 Kindeva Drug Delivery L.P. Transdermal adhesive compositions, devices, and methods
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US20120046383A1 (en) * 2010-08-19 2012-02-23 Terumo Kabushiki Kaisha Silicone rubber composition
EP3431485B2 (en) 2010-10-01 2024-09-04 ModernaTX, Inc. Engineered nucleic acids and methods of use thereof
RS54173B1 (sr) * 2010-12-14 2015-12-31 Acino Ag Transdermalni terapijski sistem za davanje aktivne supstance
KR101788802B1 (ko) * 2010-12-24 2017-10-20 주식회사 삼양바이오팜 리바스티그민을 함유하는 경피흡수제제
KR101054317B1 (ko) * 2011-01-28 2011-08-08 신신제약 주식회사 리바스티그민을 함유하는 경피흡수제제
KR101317158B1 (ko) 2011-02-18 2013-10-15 조선대학교산학협력단 갈란타민 또는 그의 염을 함유하는 경피흡수제제
WO2012135805A2 (en) 2011-03-31 2012-10-04 modeRNA Therapeutics Delivery and formulation of engineered nucleic acids
BR112013029945A2 (pt) * 2011-05-20 2017-01-31 Sk Chemicals Co Ltd emplastro contendo rivastigmina
KR20120130073A (ko) * 2011-05-20 2012-11-28 에스케이케미칼주식회사 리바스티그민 함유 패취
CN103796645B (zh) 2011-08-31 2017-06-20 东洋油墨Sc控股株式会社 贴剂
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2763701B1 (en) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
KR20140102759A (ko) 2011-12-16 2014-08-22 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
KR101399035B1 (ko) * 2011-12-22 2014-05-28 주식회사 트랜스덤 리바스티그민을 함유하는 경피흡수제제
DE102012000369A1 (de) 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
CN107441069A (zh) 2012-02-28 2017-12-08 日绊株式会社 贴附剂
WO2013142339A1 (en) 2012-03-23 2013-09-26 Novartis Ag Transdermal therapeutic system and method
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
DE18200782T1 (de) 2012-04-02 2021-10-21 Modernatx, Inc. Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
US20150051559A1 (en) * 2012-04-05 2015-02-19 Sparsha Pharma International Private Limited Transdermal patch for treatment of dementia or alzheimer type dementia
PL2859892T3 (pl) * 2012-06-12 2023-10-16 KM Transderm Ltd. Plaster
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2014028049A1 (en) * 2012-08-15 2014-02-20 Dow Corning Corporation Multi - layer transdermal drug delivery system
EP2893927A4 (en) * 2012-09-03 2016-03-09 Nipro Patch Co Ltd SKIN PATCH
KR20140038237A (ko) * 2012-09-20 2014-03-28 에스케이케미칼주식회사 리바스티그민의 안정성이 개선된 의약품
US20140083878A1 (en) * 2012-09-21 2014-03-27 Mylan Inc. Transdermal drug delivery device
WO2014051128A1 (ja) * 2012-09-28 2014-04-03 株式会社 ケイ・エム トランスダーム 貼付剤
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
CA2892529C (en) 2012-11-26 2023-04-25 Moderna Therapeutics, Inc. Terminally modified rna
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2014111790A2 (en) 2013-01-15 2014-07-24 Zydus Technologies Limited Stable transdermal pharmaceutical drug delivery system comprising rivastigmine
RU2560668C2 (ru) * 2013-03-04 2015-08-20 Общество с ограниченной ответственностью Научно-производственное объединение "Клеточные технологии" Трансдермальный седативный фармацевтический гель для лечения психоэмоциальных расстройств
AR095259A1 (es) * 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CA2906796A1 (en) * 2013-03-15 2014-09-25 Nal Pharmaceuticals Ltd. Transdermal drug delivery system containing rivastigmine
GB201309654D0 (en) 2013-05-30 2013-07-17 Euro Celtique Sa Method
TWI745577B (zh) * 2013-06-12 2021-11-11 日商Ｋｍ特蘭斯達股份有限公司 經皮吸收製劑
PL3040068T3 (pl) 2013-06-12 2022-01-10 KM Transderm Ltd. Arkusz samoprzylepny do zastosowania na skórę i kompozycja o absorpcji przezskórnej zastosowana w nim
CA2916183C (en) 2013-07-03 2022-03-29 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with electronic component
EA201690675A1 (ru) 2013-10-03 2016-08-31 Модерна Терапьютикс, Инк. Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
TWI704933B (zh) 2013-10-07 2020-09-21 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
CN105764496B (zh) 2013-10-07 2020-09-25 帝国制药美国公司 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物
TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
US20160374956A1 (en) 2013-12-12 2016-12-29 Hisamitsu Pharmaceutical Co., Inc. Multilayer type patch
CN103877063A (zh) * 2014-03-24 2014-06-25 张绪伟 一种重酒石酸卡巴拉汀胶囊及其制备方法
CN106413695B (zh) 2014-04-08 2019-12-10 帝国制药美国公司 利伐斯的明透皮组合物及其使用方法
WO2015174502A1 (ja) 2014-05-15 2015-11-19 ニチバン株式会社 リバスチグミンを含有する貼付剤のための包装体
CA2948219C (en) 2014-05-20 2023-04-04 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
JP6573913B2 (ja) 2014-05-20 2019-09-11 エルテーエス ローマン テラピー−ジステーメ アーゲー ロチゴチンを含む経皮送達システム
US11752110B2 (en) 2014-05-20 2023-09-12 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
CN204119542U (zh) 2014-09-24 2015-01-21 上海荣威塑胶工业有限公司 一种ptc加热器
CN104523656A (zh) * 2014-11-20 2015-04-22 美吉斯制药（厦门）有限公司 一种卡巴拉汀缓释透皮贴剂及其制备方法
ES3009434T3 (en) 2014-12-05 2025-03-26 Km Transderm Ltd Adhesive sheet for attachment to skin and percutaneous absorption preparation using same
DE102015107743A1 (de) 2015-05-18 2016-11-24 Bsn Medical Gmbh Silikongelbeschichtete adhäsive Schichtstruktur
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9980921B2 (en) * 2016-06-30 2018-05-29 Taho Pharmaceuticals Ltd. Transdermal delivery system containing methylphenidate or its salts and methods thereof
WO2018038022A1 (ja) 2016-08-22 2018-03-01 救急薬品工業株式会社 貼付剤
KR102506333B1 (ko) * 2016-12-20 2023-03-06 에르테에스 로만 테라피-시스테메 아게 아세나핀을 함유하는 경피흡수 치료 시스템
CN110087641B (zh) 2016-12-20 2024-03-12 罗曼治疗系统股份公司 含有阿塞那平和聚硅氧烷或聚异丁烯的透皮治疗系统
KR102033686B1 (ko) 2017-05-19 2019-10-18 보령제약 주식회사 도네페질을 함유하는 마이크로니들 경피 패치
WO2019048425A1 (en) 2017-09-05 2019-03-14 Lts Lohmann Therapie-Systeme Ag TRANSDERMAL THERAPEUTIC SYSTEM FOR TRANSDERMAL DELIVERY OF RIVASTIGMINE
EP3764997A1 (en) * 2018-03-13 2021-01-20 LTS Lohmann Therapie-Systeme AG Transdermal therapeutic system comprising a silicone acrylic hybrid polymer
WO2019175101A1 (en) * 2018-03-13 2019-09-19 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising a silicone acrylic hybrid polymer
BR112020018300A2 (pt) * 2018-03-13 2020-12-22 Lts Lohmann Therapie-Systeme Ag Sistema terapêutico transdérmico compreendendo um polímero híbrido de silicone e acrílico
CA3101418A1 (en) * 2018-06-19 2019-12-26 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing rivastigmine
CN112533593A (zh) 2018-06-20 2021-03-19 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
CN112704672A (zh) 2018-06-20 2021-04-27 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
US12151030B2 (en) 2019-01-31 2024-11-26 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
JP7549641B2 (ja) * 2019-07-09 2024-09-11 エルテーエス ローマン テラピー－ジステーメ アーゲー シリコーン含有ポリマーを含む活性剤含有層及びシリコーンゲル接着剤を含む皮膚接触層を含む経皮治療システム
WO2021005118A1 (en) * 2019-07-09 2021-01-14 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising an active agent-containing layer comprising an acrylic polymer and a skin contact layer comprising a silicone gel adhesive
CN113616625B (zh) * 2021-08-26 2023-05-30 大连科翔科技开发有限公司 一种卡巴拉汀的长效透皮贴剂
DE112024000733T5 (de) * 2023-02-01 2025-11-13 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system zur transdermalen verabreichung von huperzin a

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201906B (en) 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
US5059426A (en) * 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5252335A (en) * 1989-07-12 1993-10-12 Cygnus Therapeutic Systems Transdermal administration of lisuride
DE4301783C1 (de) * 1993-01-23 1994-02-03 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil
US6316023B1 (en) 1998-01-12 2001-11-13 Novartis Ag TTS containing an antioxidant
GB9800526D0 (en) * 1998-01-12 1998-03-11 Ciba Geigy Ag Organic compounds
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
DE19922662C1 (de) * 1999-05-18 2000-12-28 Sanol Arznei Schwarz Gmbh Transdermales therapeutisches System (TTS) Tolterodin enthaltend
AU1585601A (en) * 1999-11-04 2001-05-14 Xel Herbaceuticals Transdermal administration of huperzine
US20020192243A1 (en) * 1999-12-16 2002-12-19 Tsung-Min Hsu Transdermal and topical administration of drugs for the treatment of Alzheimer's disease using basic enhancers
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
AU2002235155A1 (en) * 2000-12-05 2002-06-18 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
DE10103860B4 (de) 2001-01-30 2004-12-23 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung
US20030060423A1 (en) * 2001-08-30 2003-03-27 Plata-Salaman Carlos R. Co-therapy for the treatment of dementia and associated behavioral manifestations comprising anticonvulsant derivatives and acetylcholinesterase inhibitors
DE10159745A1 (de) * 2001-12-05 2003-07-03 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit verbessertem Langzeittragekomfort
DE60324788D1 (de) * 2002-05-31 2009-01-02 Lundbeck & Co As H Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit
CN100339070C (zh) * 2002-10-24 2007-09-26 莫茨药物股份两合公司 包含1－氨基环己烷衍生物类和乙酰胆碱酯酶抑制剂类的药物组合物
CA2555386A1 (en) 2004-02-19 2005-09-01 Novartis Ag Use of cholinesterase inhibitors for treating vascular depression
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
EP2596889B1 (en) * 2011-11-23 2017-04-26 Sandvik Intellectual Property AB A cutting insert and a milling tool

Also Published As

Publication number Publication date
PH12013500772B1 (en) 2018-04-20
DK201300059U3 (da) 2013-05-13
DK201300014U1 (da) 2013-02-08
PT2292219E (pt) 2013-06-24
EP2292219A1 (en) 2011-03-09
KR20140072108A (ko) 2014-06-12
JP2016104737A (ja) 2016-06-09
DK201600113U1 (da) 2017-01-13
DK201300015U1 (en) 2013-02-08
IL191311A (en) 2015-02-26
SI2292219T1 (sl) 2013-08-30
PH12013500772A1 (en) 2016-01-18
BRPI0619758A2 (pt) 2011-10-18
EP2786748A1 (en) 2014-10-08
AT11185U1 (de) 2010-06-15
PL2292219T4 (pl) 2014-03-31
EP2286802A1 (en) 2011-02-23
RU2450805C2 (ru) 2012-05-20
WO2007064407A1 (en) 2007-06-07
MA30022B1 (fr) 2008-12-01
ZA200803882B (en) 2009-03-25
DE202006021172U1 (de) 2013-05-07
MY151020A (en) 2014-03-31
IL234364A (en) 2016-06-30
JP2013177419A (ja) 2013-09-09
CN101312717A (zh) 2008-11-26
TNSN08238A1 (en) 2009-10-30
US20140134230A1 (en) 2014-05-15
EP2292219B9 (en) 2015-02-18
JP2009517468A (ja) 2009-04-30
NZ568273A (en) 2011-06-30
KR20080071581A (ko) 2008-08-04
KR20210008440A (ko) 2021-01-21
EP3235495A1 (en) 2017-10-25
SG2014014989A (en) 2014-06-27
ES2414455T3 (es) 2013-07-19
DK2292219T3 (da) 2013-06-24
TWI389709B (zh) 2013-03-21
CN102048713A (zh) 2011-05-11
TW200732001A (en) 2007-09-01
US20130266633A1 (en) 2013-10-10
DK201300059U1 (da) 2013-04-29
GT200800075A (es) 2010-06-01
KR20130143729A (ko) 2013-12-31
BR122013013162A2 (pt) 2015-06-30
KR20220156666A (ko) 2022-11-25
AU2006320919A1 (en) 2007-06-07
PL2292219T3 (pl) 2013-09-30
FI10268U1 (fi) 2013-10-18
HK1153646A1 (en) 2012-04-05
DK201300015Y4 (da) 2016-02-12
IL250734A0 (en) 2017-04-30
IL234291A (en) 2017-02-28
DK201600113Y4 (da) 2017-06-09
NO20082753L (no) 2008-08-19
JP6298034B2 (ja) 2018-03-20
MY162986A (en) 2017-07-31
KR20170033449A (ko) 2017-03-24
AR057152A1 (es) 2007-11-21
DK201300014U3 (da) 2013-05-13
JP5938612B2 (ja) 2016-06-22
CA2563110A1 (en) 2007-06-01
DE14163637T1 (de) 2015-06-03
PH12013500771A1 (en) 2016-01-18
AR097045A2 (es) 2016-02-17
AU2006320919B2 (en) 2011-04-28
EP1959937A1 (en) 2008-08-27
US20070128263A1 (en) 2007-06-07
EP2292219B1 (en) 2013-06-12
ECSP088469A (es) 2008-07-30
RU2008126459A (ru) 2010-01-20

Similar Documents

Publication Publication Date Title
KR20180050441A (ko) 경피용 치료학적 시스템
US9248104B2 (en) Transdermal methods and systems for treating Alzheimer's disease
TWI621448B (zh) 里曼提明（ｒｉｖａｓｔｉｇｍｉｎｅ）經皮組成物及使用其之方法
MX2008006956A (es) Sistema terapeutico transdermico
HK1153646B (en) Transdermal therapeutic system for the administration of rivastigmine
HK1151740A (en) Transdermal therapeutic system

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20180504

Application number text: 1020177006994

Filing date: 20170314

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20180604

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20180814

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20200914

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20180814

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20201214

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20200914

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20220128

Appeal identifier: 2020101003031

Request date: 20201214

A107 Divisional application of patent
AMND Amendment
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20210113

Application number text: 1020177006994

Filing date: 20170314

PB0901 Examination by re-examination before a trial

Comment text: Amendment to Specification, etc.

Patent event date: 20210113

Patent event code: PB09011R02I

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20201214

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20200529

Patent event code: PB09011R02I

PB0601 Maintenance of original decision after re-examination before a trial
J301 Trial decision

Free format text: TRIAL NUMBER: 2020101003031; TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20201214

Effective date: 20211202

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20211202

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 20201214

Decision date: 20220128

Appeal identifier: 2020101003031

J121 Written withdrawal of request for trial
PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20220128

PJ1201 Withdrawal of trial

Patent event code: PJ12011R01D

Patent event date: 20220128

Comment text: Written Withdrawal of Request for Trial

Appeal identifier: 2020101003031

Request date: 20201214

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20220128