KR20140136934A - 알부민 변이체 - Google Patents

알부민 변이체 Download PDF

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Publication number
KR20140136934A
KR20140136934A KR1020147024412A KR20147024412A KR20140136934A KR 20140136934 A KR20140136934 A KR 20140136934A KR 1020147024412 A KR1020147024412 A KR 1020147024412A KR 20147024412 A KR20147024412 A KR 20147024412A KR 20140136934 A KR20140136934 A KR 20140136934A
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KR
South Korea
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glu
leu
lys
ala
val
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KR1020147024412A
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English (en)
Korean (ko)
Inventor
카렌 앤 델라헤이
Original Assignee
노보자임스 바이오파마 디케이 에이/에스
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Priority claimed from PCT/EP2012/058206 external-priority patent/WO2012150319A1/en
Application filed by 노보자임스 바이오파마 디케이 에이/에스 filed Critical 노보자임스 바이오파마 디케이 에이/에스
Publication of KR20140136934A publication Critical patent/KR20140136934A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147024412A 2012-03-16 2013-03-15 알부민 변이체 Ceased KR20140136934A (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP12160007.6 2012-03-16
EP12160007 2012-03-16
PCT/EP2012/058206 WO2012150319A1 (en) 2011-05-05 2012-05-04 Albumin variants
EPPCT/EP2012/058206 2012-05-04
EP12187326 2012-10-05
EP12187326.9 2012-10-05
EP12191086 2012-11-02
EP12191086.3 2012-11-02
EP12191854.4 2012-11-08
EP12191854 2012-11-08
PCT/EP2013/055487 WO2013135896A1 (en) 2012-03-16 2013-03-15 Albumin variants

Publications (1)

Publication Number Publication Date
KR20140136934A true KR20140136934A (ko) 2014-12-01

Family

ID=49160283

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147024412A Ceased KR20140136934A (ko) 2012-03-16 2013-03-15 알부민 변이체

Country Status (14)

Country Link
US (3) US9944691B2 (enExample)
EP (2) EP3330283A3 (enExample)
JP (2) JP6441682B2 (enExample)
KR (1) KR20140136934A (enExample)
CN (1) CN104736559B (enExample)
AU (2) AU2013234299B2 (enExample)
BR (1) BR112014018679A2 (enExample)
CA (1) CA2861592A1 (enExample)
DK (1) DK2825556T3 (enExample)
ES (1) ES2664328T3 (enExample)
IL (1) IL233689A0 (enExample)
MX (1) MX2014010278A (enExample)
PL (1) PL2825556T3 (enExample)
WO (1) WO2013135896A1 (enExample)

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JP6749312B2 (ja) 2014-07-31 2020-09-02 アムゲン リサーチ （ミュンヘン） ゲーエムベーハーＡＭＧＥＮ Ｒｅｓｅａｒｃｈ（Ｍｕｎｉｃｈ）ＧｍｂＨ 最適化された種間特異的二重特異性単鎖抗体コンストラクト
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