KR20110049802A - 중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도 - Google Patents

중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도 Download PDF

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KR20110049802A
KR20110049802A KR1020117003495A KR20117003495A KR20110049802A KR 20110049802 A KR20110049802 A KR 20110049802A KR 1020117003495 A KR1020117003495 A KR 1020117003495A KR 20117003495 A KR20117003495 A KR 20117003495A KR 20110049802 A KR20110049802 A KR 20110049802A
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seq
antibody
antigen
influenza
binding fragment
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안토니오 란차페히아
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인스티튜트 포 리서치 인 바이오메드슨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020117003495A 2008-07-25 2009-07-27 중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도 Withdrawn KR20110049802A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8383808P 2008-07-25 2008-07-25
US61/083,838 2008-07-25
US18158209P 2009-05-27 2009-05-27
US61/181,582 2009-05-27

Publications (1)

Publication Number Publication Date
KR20110049802A true KR20110049802A (ko) 2011-05-12

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KR1020117003495A Withdrawn KR20110049802A (ko) 2008-07-25 2009-07-27 중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도
KR1020117003526A Active KR101732056B1 (ko) 2008-07-25 2009-07-27 중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도

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US (2) US8685402B2 (cg-RX-API-DMAC10.html)
EP (2) EP2313112B1 (cg-RX-API-DMAC10.html)
JP (3) JP5607620B2 (cg-RX-API-DMAC10.html)
KR (2) KR20110049802A (cg-RX-API-DMAC10.html)
CN (2) CN102216327A (cg-RX-API-DMAC10.html)
AU (2) AU2009275226B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0911699B8 (cg-RX-API-DMAC10.html)
CA (2) CA2731686C (cg-RX-API-DMAC10.html)
CO (1) CO6341572A2 (cg-RX-API-DMAC10.html)
CR (2) CR20110079A (cg-RX-API-DMAC10.html)
EC (1) ECSP11010823A (cg-RX-API-DMAC10.html)
ES (1) ES2662519T3 (cg-RX-API-DMAC10.html)
GT (1) GT201100023A (cg-RX-API-DMAC10.html)
IL (2) IL210771A0 (cg-RX-API-DMAC10.html)
MA (1) MA32577B1 (cg-RX-API-DMAC10.html)
MX (2) MX2011000767A (cg-RX-API-DMAC10.html)
NZ (2) NZ590890A (cg-RX-API-DMAC10.html)
RU (1) RU2553325C2 (cg-RX-API-DMAC10.html)
WO (2) WO2010010466A2 (cg-RX-API-DMAC10.html)
ZA (2) ZA201101113B (cg-RX-API-DMAC10.html)

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