KR20100111683A - 극히 지연된 시간-작용 프로필을 갖는 신규 인슐린 유도체 - Google Patents
극히 지연된 시간-작용 프로필을 갖는 신규 인슐린 유도체 Download PDFInfo
- Publication number
- KR20100111683A KR20100111683A KR1020107014964A KR20107014964A KR20100111683A KR 20100111683 A KR20100111683 A KR 20100111683A KR 1020107014964 A KR1020107014964 A KR 1020107014964A KR 20107014964 A KR20107014964 A KR 20107014964A KR 20100111683 A KR20100111683 A KR 20100111683A
- Authority
- KR
- South Korea
- Prior art keywords
- corresponds
- insulin
- arg
- insulin analogue
- glu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008003566.1 | 2008-01-09 | ||
| DE102008003566A DE102008003566A1 (de) | 2008-01-09 | 2008-01-09 | Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil |
| US4466208P | 2008-04-14 | 2008-04-14 | |
| US61/044,662 | 2008-04-14 | ||
| DE200810025007 DE102008025007A1 (de) | 2008-05-24 | 2008-05-24 | Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil |
| DE102008025007.4 | 2008-05-24 |
Publications (1)
| Publication Number | Publication Date |
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| KR20100111683A true KR20100111683A (ko) | 2010-10-15 |
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| KR1020107014964A Ceased KR20100111683A (ko) | 2008-01-09 | 2009-01-06 | 극히 지연된 시간-작용 프로필을 갖는 신규 인슐린 유도체 |
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| Country | Link |
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| US (1) | US8633156B2 (https=) |
| EP (1) | EP2229406B1 (https=) |
| JP (1) | JP5695909B2 (https=) |
| KR (1) | KR20100111683A (https=) |
| CN (1) | CN101970476B (https=) |
| AR (1) | AR070119A1 (https=) |
| AU (1) | AU2009203810B2 (https=) |
| BR (1) | BRPI0907119A2 (https=) |
| CA (1) | CA2711752A1 (https=) |
| CL (1) | CL2009000018A1 (https=) |
| CO (1) | CO6290770A2 (https=) |
| IL (1) | IL206843A0 (https=) |
| MA (1) | MA31997B1 (https=) |
| NZ (1) | NZ586589A (https=) |
| PA (1) | PA8811501A1 (https=) |
| PE (1) | PE20091305A1 (https=) |
| TW (1) | TWI433681B (https=) |
| UY (1) | UY31597A1 (https=) |
| WO (1) | WO2009087082A2 (https=) |
| ZA (1) | ZA201003927B (https=) |
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| WO2015108398A1 (ko) * | 2014-01-20 | 2015-07-23 | 한미약품 주식회사 | 지속형 인슐린 및 그 용도 |
| US10017557B2 (en) | 2015-08-28 | 2018-07-10 | Hanmi Pharm. Co., Ltd. | Insulin analogs and use thereof |
| US10159715B2 (en) | 2014-05-29 | 2018-12-25 | Hanmi Pharm. Co., Ltd | Method for treating diabetes comprising long-acting insulin analogue conjugate and long-acting insulinotropic peptide conjugate |
| US10188703B2 (en) | 2014-05-30 | 2019-01-29 | Hanmi Pharm. Co., Ltd. | Method for treating diabetes mellitus by a composition comprising insulin and a GLP-1/glucagon dual agonist |
| US11396534B2 (en) | 2016-09-23 | 2022-07-26 | Hanmi Pharm. Co., Ltd. | Insulin analogs with reduced affinity to insulin receptor and use thereof |
| US11752216B2 (en) | 2017-03-23 | 2023-09-12 | Hanmi Pharm. Co., Ltd. | Insulin analog complex with reduced affinity for insulin receptor and use thereof |
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| DE102005046113A1 (de) * | 2005-09-27 | 2007-03-29 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Amidierung von Polypetiden mit C-terminalen basischen Aminosäuren unter Verwendung spezifischer Endoproteasen |
| CN102007143B (zh) * | 2008-01-09 | 2015-08-26 | 塞诺菲-安万特德国有限公司 | 具有超延迟时效特征的新型胰岛素衍生物 |
| CN102256618A (zh) | 2008-10-17 | 2011-11-23 | 赛诺菲-安万特德国有限公司 | 胰岛素和glp-1激动剂的组合 |
| KR20110126592A (ko) | 2008-12-15 | 2011-11-23 | 질랜드 파마 에이/에스 | 글루카곤 유사체 |
| US8685919B2 (en) | 2008-12-15 | 2014-04-01 | Zealand Pharma A/S | Glucagon analogues |
| JP5635531B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
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| PL2451437T3 (pl) | 2009-07-06 | 2017-05-31 | Sanofi-Aventis Deutschland Gmbh | Wodne preparaty insuliny zawierające metioninę |
| AP3329A (en) | 2009-07-13 | 2015-06-30 | Zealand Pharma As | Acylated glucagon analogues |
| TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
| NZ599847A (en) | 2009-11-13 | 2013-09-27 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a glp-1 agonist and methionine |
| UY33462A (es) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | Analogos de glucagon |
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| KR20130093012A (ko) | 2010-06-24 | 2013-08-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
| WO2012028172A1 (en) | 2010-08-30 | 2012-03-08 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| US20120283169A1 (en) | 2010-11-08 | 2012-11-08 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| KR20140043709A (ko) | 2011-01-20 | 2014-04-10 | 질랜드 파마 에이/에스 | 아실화 글루카곤 유사체와 인슐린 유사체의 조합 |
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| UA113626C2 (xx) * | 2011-06-02 | 2017-02-27 | Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії | |
| AR087693A1 (es) | 2011-08-29 | 2014-04-09 | Sanofi Aventis Deutschland | Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
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| TWI780236B (zh) | 2013-02-04 | 2022-10-11 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
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| WO2015055801A1 (en) | 2013-10-17 | 2015-04-23 | Zealand Pharma A/S | Acylated glucagon analogues |
| MX2016005556A (es) | 2013-11-06 | 2016-07-15 | Zealand Pharma As | Compuestos agonistas duales de gip-glp-1 y procedimientos. |
| AU2014345570B2 (en) | 2013-11-06 | 2019-01-24 | Zealand Pharma A/S | Glucagon-GLP-1-GIP triple agonist compounds |
| CN105960249B (zh) | 2014-01-09 | 2021-03-16 | 赛诺菲 | 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂 |
| US9895423B2 (en) | 2014-01-09 | 2018-02-20 | Sanofi | Stabilized pharmaceutical formulations of insulin aspart |
| JP6723921B2 (ja) | 2014-01-09 | 2020-07-15 | サノフイＳａｎｏｆｉ | インスリンアナログおよび／またはインスリン誘導体の、グリセリンを含まない安定化された医薬製剤 |
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- 2009-01-06 AU AU2009203810A patent/AU2009203810B2/en not_active Ceased
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- 2009-01-06 BR BRPI0907119-9A patent/BRPI0907119A2/pt not_active Application Discontinuation
- 2009-01-06 WO PCT/EP2009/000018 patent/WO2009087082A2/de not_active Ceased
- 2009-01-07 CL CL2009000018A patent/CL2009000018A1/es unknown
- 2009-01-07 PE PE2009000010A patent/PE20091305A1/es not_active Application Discontinuation
- 2009-01-07 TW TW098100283A patent/TWI433681B/zh not_active IP Right Cessation
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015108398A1 (ko) * | 2014-01-20 | 2015-07-23 | 한미약품 주식회사 | 지속형 인슐린 및 그 용도 |
| US10253082B2 (en) | 2014-01-20 | 2019-04-09 | Hanmi Pharm. Co., Ltd | Long-acting insulin and use thereof |
| US10159715B2 (en) | 2014-05-29 | 2018-12-25 | Hanmi Pharm. Co., Ltd | Method for treating diabetes comprising long-acting insulin analogue conjugate and long-acting insulinotropic peptide conjugate |
| US10188703B2 (en) | 2014-05-30 | 2019-01-29 | Hanmi Pharm. Co., Ltd. | Method for treating diabetes mellitus by a composition comprising insulin and a GLP-1/glucagon dual agonist |
| US10017557B2 (en) | 2015-08-28 | 2018-07-10 | Hanmi Pharm. Co., Ltd. | Insulin analogs and use thereof |
| US10647753B2 (en) | 2015-08-28 | 2020-05-12 | Hanmi Pharm. Co., Ltd. | Insulin analogs and use thereof |
| US11396534B2 (en) | 2016-09-23 | 2022-07-26 | Hanmi Pharm. Co., Ltd. | Insulin analogs with reduced affinity to insulin receptor and use thereof |
| US11752216B2 (en) | 2017-03-23 | 2023-09-12 | Hanmi Pharm. Co., Ltd. | Insulin analog complex with reduced affinity for insulin receptor and use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2229406B1 (de) | 2015-04-22 |
| US8633156B2 (en) | 2014-01-21 |
| WO2009087082A2 (de) | 2009-07-16 |
| CN101970476B (zh) | 2014-08-27 |
| AU2009203810B2 (en) | 2013-07-25 |
| TWI433681B (zh) | 2014-04-11 |
| PE20091305A1 (es) | 2009-09-26 |
| EP2229406A2 (de) | 2010-09-22 |
| BRPI0907119A2 (pt) | 2015-07-14 |
| AR070119A1 (es) | 2010-03-17 |
| NZ586589A (en) | 2012-04-27 |
| WO2009087082A3 (de) | 2009-09-24 |
| ZA201003927B (en) | 2011-04-28 |
| CA2711752A1 (en) | 2009-07-16 |
| JP2011509269A (ja) | 2011-03-24 |
| AU2009203810A1 (en) | 2009-07-16 |
| MA31997B1 (fr) | 2011-01-03 |
| CO6290770A2 (es) | 2011-06-20 |
| PA8811501A1 (es) | 2009-09-17 |
| UY31597A1 (es) | 2009-08-31 |
| US20110173722A1 (en) | 2011-07-14 |
| JP5695909B2 (ja) | 2015-04-08 |
| IL206843A0 (en) | 2010-12-30 |
| TW200942257A (en) | 2009-10-16 |
| HK1148542A1 (en) | 2011-09-09 |
| CL2009000018A1 (es) | 2009-06-05 |
| CN101970476A (zh) | 2011-02-09 |
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