KR20100032886A - 키나제 억제제로서의 5-헤테로아릴 치환된 인다졸 - Google Patents

키나제 억제제로서의 5-헤테로아릴 치환된 인다졸 Download PDF

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Publication number
KR20100032886A
KR20100032886A KR1020107000409A KR20107000409A KR20100032886A KR 20100032886 A KR20100032886 A KR 20100032886A KR 1020107000409 A KR1020107000409 A KR 1020107000409A KR 20107000409 A KR20107000409 A KR 20107000409A KR 20100032886 A KR20100032886 A KR 20100032886A
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South Korea
Prior art keywords
indazol
triazol
benzyl
carboxamide
indazole
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KR1020107000409A
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English (en)
Korean (ko)
Inventor
이리니 아크리토폴루-잔제
브라이언 디 웨이크필드
헬무트 마크
제안 씨 투르너
알란 에프 가시키
비자야 제이 그라시아스
케시 새리스
더글라스 엠 캘빈
멜리사 제이 미츠머휴젠
치 솨이
죠티 알 파텔
마가레타 바커
니콜레 토이슈
에릭 에프. 존슨
피터 제이 코바
스티반 더블유 드주릭
앤드류 제이 롱
아닐 바수데반
아드리안 홉슨
존 무어 니겔 세인트.
루 왕
던 조지
비킨 리
크리스틴 프랑크
Original Assignee
아보트 러보러터리즈
애보트 게엠베하 운트 콤파니 카게
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Publication of KR20100032886A publication Critical patent/KR20100032886A/ko

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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
KR1020107000409A 2007-06-08 2008-06-04 키나제 억제제로서의 5-헤테로아릴 치환된 인다졸 KR20100032886A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93396007P 2007-06-08 2007-06-08
US60/933,960 2007-06-08

Publications (1)

Publication Number Publication Date
KR20100032886A true KR20100032886A (ko) 2010-03-26

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ID=39951673

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KR1020107000409A KR20100032886A (ko) 2007-06-08 2008-06-04 키나제 억제제로서의 5-헤테로아릴 치환된 인다졸

Country Status (13)

Country Link
EP (1) EP2167491A1 (ja)
JP (2) JP5451602B2 (ja)
KR (1) KR20100032886A (ja)
CN (1) CN101790526A (ja)
AU (1) AU2008262038A1 (ja)
BR (1) BRPI0811065A2 (ja)
CA (1) CA2689117A1 (ja)
IL (1) IL202318A0 (ja)
MX (1) MX2009013213A (ja)
RU (1) RU2487873C2 (ja)
SG (1) SG182187A1 (ja)
WO (1) WO2008154241A1 (ja)
ZA (1) ZA200908624B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
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WO2023068835A1 (ko) * 2021-10-20 2023-04-27 전북대학교산학협력단 Ｐａｋ4 저해제 및 그의 용도
KR102607237B1 (ko) * 2023-06-07 2023-11-30 주식회사 젠센 신규한 트리아졸이 치환된 인다졸 유도체 및 이의 용도

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MY152271A (en) 2008-02-21 2014-09-15 Merck Sharp & Dohme Novel compounds that are erk inhibitors
AR071780A1 (es) * 2008-05-15 2010-07-14 Nerviano Medical Sciences Srl Derivados de carbamoilo de carbonilamino-pirazoles biciclicos como profarmacos
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HUE028259T2 (en) 2009-08-10 2016-12-28 Samumed Llc Inhibitors of Wnt signaling signal indazole and their therapeutic use
CN104546846B (zh) 2009-12-21 2017-04-12 萨穆梅德有限公司 1H‑吡唑并[3,4‑b]吡啶及其治疗应用
UY33213A (es) * 2010-02-18 2011-09-30 Almirall Sa Derivados de pirazol como inhibidores de jak
KR101233082B1 (ko) 2010-02-25 2013-02-14 주식회사 이큐스앤자루 신규한 이미다졸피라진 유도체 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스 치료용 약학적 조성물
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