KR20080007380A - 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 - Google Patents

지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 Download PDF

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Publication number
KR20080007380A
KR20080007380A KR1020077027301A KR20077027301A KR20080007380A KR 20080007380 A KR20080007380 A KR 20080007380A KR 1020077027301 A KR1020077027301 A KR 1020077027301A KR 20077027301 A KR20077027301 A KR 20077027301A KR 20080007380 A KR20080007380 A KR 20080007380A
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South Korea
Prior art keywords
peptide
self
composition
formulation
assembled
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Ceased
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KR1020077027301A
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English (en)
Korean (ko)
Inventor
루틀리지 엘리스-벤케
슈구앙 장
제랄드 슈나이더
궉-파이 소
데이비드 타이
유-시앙 리앙
Original Assignee
메사추세츠 인스티튜트 오브 테크놀로지
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36939225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20080007380(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 메사추세츠 인스티튜트 오브 테크놀로지 filed Critical 메사추세츠 인스티튜트 오브 테크놀로지
Publication of KR20080007380A publication Critical patent/KR20080007380A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • C01G23/04—Oxides; Hydroxides
    • C01G23/047—Titanium dioxide
    • C01G23/07—Producing by vapour phase processes, e.g. halide oxidation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/06—Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/08—Heat treatment
    • B01J37/10—Heat treatment in the presence of water, e.g. steam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00—Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
KR1020077027301A 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 Ceased KR20080007380A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67461205P 2005-04-25 2005-04-25
US60/674,612 2005-04-25
US75882706P 2006-01-13 2006-01-13
US60/758,827 2006-01-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020107019627A Division KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20080007380A true KR20080007380A (ko) 2008-01-18

Family

ID=36939225

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020077027301A Ceased KR20080007380A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법
KR1020107019627A Ceased KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020107019627A Ceased KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Country Status (11)

Country Link
US (3) US9327010B2 (OSRAM)
EP (2) EP2283851B1 (OSRAM)
JP (3) JP5204646B2 (OSRAM)
KR (2) KR20080007380A (OSRAM)
CN (1) CN101267831B (OSRAM)
AU (1) AU2006241123B2 (OSRAM)
CA (1) CA2609656C (OSRAM)
DK (1) DK1879606T3 (OSRAM)
ES (1) ES2427565T3 (OSRAM)
IL (3) IL186779A (OSRAM)
WO (1) WO2006116524A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123375A1 (ko) * 2013-02-06 2014-08-14 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3031466B1 (en) 2004-07-06 2018-11-28 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
ES2427565T3 (es) 2005-04-25 2013-10-31 Massachusetts Institute Of Technology Péptidos autoensambladores para promover la hemostasia
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
US9364412B2 (en) * 2005-11-14 2016-06-14 University Of Utah Research Foundation Electrostatically controlled hydrogels
AU2014203694B2 (en) * 2006-04-25 2016-08-11 Massachusetts Institute Of Technology Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
HUE037994T2 (hu) * 2006-04-25 2018-09-28 Massachusetts Inst Technology Készítmények és eljárások szennyezõ anyagok, testfolyadékok vagy más anyagok mozgásának befolyásolására és/vagy más fiziológiai állapotok befolyásolására
JP5496671B2 (ja) 2006-09-26 2014-05-21 マサチューセッツ インスティテュート オブ テクノロジー 修飾自己組織化ペプチド
US7696309B2 (en) 2006-10-23 2010-04-13 The Brigham And Women's Hospital, Inc. Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
US9012404B2 (en) 2006-12-11 2015-04-21 3D Matrix, Inc. Compositions and methods for cardiac tissue protection and regeneration
EP2146733B1 (en) * 2007-03-14 2020-11-25 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
EP2157937B1 (en) 2007-06-04 2017-03-22 Sequent Medical, Inc. Devices for treatment of vascular defects
US7906478B2 (en) 2007-07-20 2011-03-15 The Procter & Gamble Company Personal-care articles having self-assembling peptides
WO2009067711A2 (en) 2007-11-21 2009-05-28 T.J. Smith & Nephew, Limited Suction device and dressing
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
CN104382691B (zh) 2007-11-21 2018-08-31 史密夫及内修公开有限公司 伤口包敷物
ES2534770T3 (es) * 2007-12-05 2015-04-28 3-D Matrix, Ltd. Material para la curación de heridas y la reconstrucción de la piel
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
US20090169521A1 (en) * 2007-12-31 2009-07-02 Technion Research & Development Foundation Ltd. Vascularized cardiac tissue and methods of producing and using same
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
US8828358B2 (en) * 2008-03-11 2014-09-09 Materials Modifications, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide
US8852558B2 (en) * 2008-03-11 2014-10-07 Materials Modification, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst
WO2009123903A1 (en) * 2008-04-03 2009-10-08 Zymogenetics, Inc. Hemostatic microspheres
EP2279023B1 (en) 2008-05-02 2020-12-02 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CN101302249B (zh) * 2008-06-24 2011-08-17 四川大学 一种自组装短肽及其在制备抗肿瘤药物中的应用
EP3238749B2 (en) 2008-10-06 2025-06-04 3-D Matrix, Ltd. Tissue plug
CN101514225B (zh) * 2008-10-13 2011-09-14 西安蓝晶生物科技有限公司 自聚体多肽及其制备方法和应用
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
KR101736169B1 (ko) 2009-03-16 2017-05-16 닛산 가가쿠 고교 가부시키 가이샤 저분자 겔화제로 이루어진 스프레이용 기재
WO2010148400A1 (en) * 2009-06-19 2010-12-23 Vanderbilt University Direct visualization catheter
US20110081398A1 (en) * 2009-10-01 2011-04-07 Tyco Healthcare Group Lp Multi-mechanism surgical compositions
WO2011057002A2 (en) 2009-11-05 2011-05-12 Sequent Medical Inc. Multiple layer filamentary devices or treatment of vascular defects
WO2011072482A1 (en) * 2009-12-14 2011-06-23 The University Of Hong Kong Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells
WO2011084509A1 (en) * 2009-12-15 2011-07-14 Massachusetts Institute Of Technology Endothelial basement membrane targeting peptide ligands
US9308277B2 (en) 2010-02-25 2016-04-12 Mesoblast International Sàrl Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
US9687591B2 (en) 2010-03-31 2017-06-27 Agency For Science, Technology And Research Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes
US8999916B2 (en) 2010-03-31 2015-04-07 Agency For Science, Technology And Research Crosslinked peptide hydrogels
US9067084B2 (en) 2010-03-31 2015-06-30 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
US8741833B2 (en) 2010-07-16 2014-06-03 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
CN107033596A (zh) 2010-11-25 2017-08-11 史密夫及内修公开有限公司 组合物i – ii及其产品和用途
US8546338B2 (en) 2010-12-08 2013-10-01 Johnson & Johnson Consumer Companies, Inc. Self-assembling hydrogels based on dicephalic peptide amphiphiles
JP6084352B2 (ja) * 2010-12-24 2017-02-22 国立大学法人 岡山大学 高強度ペプチドゲル
CN103747795A (zh) 2011-06-07 2014-04-23 美索布拉斯特国际有限公司 使用基质细胞衍生因子-1的蛋白酶抵抗突变体修复组织损伤的方法
WO2013025685A1 (en) * 2011-08-14 2013-02-21 Materials Modification, Inc. Method and composition for in situ formation of an artificial blockage to control blood loss
EP2750687B1 (en) * 2011-09-02 2017-12-06 3-D Matrix, Ltd. Amphiphilic peptides for thoracic air leakage occlusion
US10905708B2 (en) 2011-09-07 2021-02-02 3-D Matrix, Ltd. MicroRNA-based methods and assays for osteocarcinoma
US11260072B2 (en) 2011-09-07 2022-03-01 3-D Matrix, Ltd. MicroRNA-based methods and assays for osteocarcinoma
GB2496654A (en) * 2011-11-18 2013-05-22 Reckitt & Colman Overseas Self-assembling peptides
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
EP3466964A1 (en) * 2012-07-06 2019-04-10 3-D Matrix Ltd. Fill-finish process for peptide solutions
JP6183831B2 (ja) * 2012-10-23 2017-08-23 義之 小山 ハイドロゲル形成材
US9241891B2 (en) 2012-10-30 2016-01-26 The Procter & Gamble Company Personal care compositions comprising self-assembling peptides
JP6376562B2 (ja) 2012-12-25 2018-08-22 扶桑薬品工業株式会社 止血剤アプリケータ
EP2958933B1 (en) * 2013-01-28 2018-08-22 Agency For Science, Technology And Research Crosslinked peptide hydrogels
KR102045030B1 (ko) * 2013-02-08 2019-11-15 재단법인 아산사회복지재단 지혈요소가 구비된 의료기구
BR112015021446A2 (pt) * 2013-03-06 2017-10-10 3D Matrix Ltd métodos cirúrgicos empregando composições de peptídeo amfifílico purificado
WO2014141160A1 (en) * 2013-03-14 2014-09-18 3-D Matrix, Ltd Treatment for bile leakage
JP6134050B2 (ja) 2013-03-14 2017-05-24 マサチューセッツ インスティテュート オブ テクノロジー ヒト抗体の長期間持続放出のための多層注射可能自己組織化ペプチドスキャホールドヒドロゲル
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
EP2968651B1 (en) * 2013-03-15 2020-10-21 Cook Medical Technologies LLC Adhesive medical products and methods for treating gastrointestinal lesions
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
EP2968647B1 (en) 2013-03-15 2022-06-29 Smith & Nephew plc Wound dressing sealant and use thereof
JP6857857B2 (ja) * 2013-04-30 2021-04-14 国立大学法人九州工業大学 ペプチドおよびその自己集合方法、その集合体、これらを用いた細胞培養基材、並びに、細胞シートの製造方法
US10765774B2 (en) * 2013-07-09 2020-09-08 Ethicon, Inc. Hemostatic pad assembly kit and method
US9078658B2 (en) 2013-08-16 2015-07-14 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US9955976B2 (en) 2013-08-16 2018-05-01 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CN105658252A (zh) * 2013-08-22 2016-06-08 阿奇生物外科有限公司 用于控制流体移动的可植入网状物
CN103656618B (zh) * 2013-10-25 2016-06-08 广东药学院 治疗皮肤创伤的多肽纳米纤维凝胶制剂、制备方法及应用
CN103665110B (zh) * 2013-12-06 2015-10-28 华南理工大学 半程电荷互补型手性自组装短肽纳米生物医药材料及应用
JP2015142720A (ja) * 2013-12-27 2015-08-06 株式会社メニコン 止血材
JP6490897B2 (ja) * 2013-12-27 2019-03-27 株式会社メニコンネクト 自己組織化ペプチドゲル
WO2015138478A1 (en) 2014-03-10 2015-09-17 3-D Matrix, Ltd. Autoassembling peptides for the treatment of pulmonary bulla
EP3628337B1 (en) 2014-03-10 2025-05-28 3-D Matrix, Ltd. Sterilization and filtration of peptide compositions
CN117138022A (zh) 2014-03-10 2023-12-01 三维矩阵有限责任公司 自组装肽组合物
WO2015145797A1 (ja) * 2014-03-28 2015-10-01 大塚化学株式会社 止血用医薬組成物
US9629635B2 (en) 2014-04-14 2017-04-25 Sequent Medical, Inc. Devices for therapeutic vascular procedures
EP3167914B1 (en) * 2014-07-11 2021-09-29 Menicon Co., Ltd. Visibility-ensuring material, and device for discharging visibility-ensuring material
DE102015000363A1 (de) 2015-01-20 2016-07-21 Emc Microcollections Gmbh Neue modular funktionalisierbare Peptid-Hydrogele
KR20180102583A (ko) * 2015-12-18 2018-09-17 가부시끼가이샤 쓰리디 매트릭스 지혈용 조성물 및 지혈용 조성물을 이용한 지혈방법
US10814038B2 (en) 2016-01-06 2020-10-27 3-D Matrix, Ltd. Combination compositions
CN109152868A (zh) * 2016-03-18 2019-01-04 立美基股份有限公司 防止生物组织粘连
EP3429645A1 (en) * 2016-03-18 2019-01-23 3-D Matrix, Ltd Cerebrospinal fluid leakage occlusion
US20200078489A1 (en) * 2016-03-18 2020-03-12 3-D Matrix, Ltd. Pancreatic fistula occlusion
US20200282100A1 (en) * 2016-06-01 2020-09-10 3-D Matrix, Ltd. Hemostatic Dressings with Self-Assembling Peptide Hydrogels
WO2017210421A1 (en) * 2016-06-01 2017-12-07 3-D Matrix, Ltd. Hemostatic powders with self-assembling peptide hydrogels
JP6912953B2 (ja) * 2016-06-27 2021-08-04 三洋化成工業株式会社 体液漏出防止剤
JP7012950B2 (ja) 2016-11-17 2022-01-31 地方独立行政法人東京都立産業技術研究センター 生体組織孔閉鎖用、潰瘍保護用及び血管塞栓療術用ゾル
US11174288B2 (en) * 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
CN106701724B (zh) * 2016-12-27 2019-10-08 江南大学 一种碱性果胶酶活性包涵体的制备及其应用
CN107529533B (zh) * 2017-09-07 2020-10-30 中国药科大学 一类可自组装成水凝胶的pH敏感多肽及其作为装载药物材料的应用
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
CN107802883B (zh) * 2017-12-09 2020-08-14 青岛市妇女儿童医院 一种伤口清洗液
EP3723726A1 (en) 2017-12-15 2020-10-21 3-D Matrix, Ltd. Surfactant peptide nanostructures and uses in drug delivery
WO2019183625A1 (en) 2018-03-23 2019-09-26 Arch Biosurgery, Inc. Sap and peptidomimetic compositions for reducing symptoms of inflammation
CN112165954A (zh) * 2018-03-23 2021-01-01 阿奇生物外科有限公司 用于治疗眼病的sap和拟肽
CN108517006B (zh) * 2018-05-10 2021-05-28 暨南大学 一种常温常压条件下改善碳纳米管在水中分散性的多肽材料及其应用
JP7142286B2 (ja) * 2018-07-13 2022-09-27 慶應義塾 セレン含有アミノ酸を含む糖鎖－ポリペプチド複合体、および、その医薬用途
EP3861115A1 (en) * 2018-10-05 2021-08-11 Basf Se Compounds stabilizing hydrolases in liquids
JP7437315B2 (ja) * 2018-10-05 2024-02-22 学校法人 久留米大学 腸管における潰瘍または瘻孔の治療または予防のための医薬組成物
CN109136165A (zh) * 2018-10-16 2019-01-04 罗忠礼 一种自组装短肽在皮肤组织创伤中快速修复的应用
CN109646711A (zh) * 2019-01-29 2019-04-19 青岛中腾生物技术有限公司 一种医用止血封闭防黏连材料
US11317921B2 (en) 2019-03-15 2022-05-03 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CN113573650B (zh) 2019-03-15 2024-05-28 后续医疗股份有限公司 用于治疗血管缺陷的具有柔性连接部的丝装置
US11559309B2 (en) 2019-03-15 2023-01-24 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CN110256572B (zh) * 2019-05-07 2022-11-01 西北大学 一种rhc-(rada)4融合蛋白
WO2020252003A1 (en) 2019-06-13 2020-12-17 Hollister Incorporated Reusable urinary catheter products
US12440644B2 (en) 2019-06-25 2025-10-14 Hollister Incorporated Reusable urinary catheter products
CN110396124B (zh) * 2019-08-21 2021-04-13 上海交通大学 自组装多肽及其作为止血剂的用途
US12390552B2 (en) 2020-01-13 2025-08-19 Arch Biosurgery, Inc. Self-assembling peptide gel formulation and methods of use
US12070220B2 (en) 2020-03-11 2024-08-27 Microvention, Inc. Devices having multiple permeable shells for treatment of vascular defects
US12023034B2 (en) 2020-03-11 2024-07-02 Microvention, Inc. Devices for treatment of vascular defects
US20210282789A1 (en) 2020-03-11 2021-09-16 Microvention, Inc. Multiple layer devices for treatment of vascular defects
CN111848736B (zh) * 2020-08-05 2021-12-31 赛克赛斯生物科技股份有限公司 自组装多肽、制备方法、自组装多肽制剂及应用
CN112386737B (zh) * 2020-11-23 2022-07-26 上海交通大学 一种限制伤口部位的体液溢出的组合物
CN113046884B (zh) * 2021-03-25 2022-06-10 台州市中心医院（台州学院附属医院） 一种抗菌可降解医用缝合线
US12446891B2 (en) 2021-08-30 2025-10-21 Microvention, Inc. Devices for treatment of vascular defects
CN114230640A (zh) * 2021-12-21 2022-03-25 西安交通大学 一种具有自组装能力的氨基酸缩合物
WO2023215479A1 (en) * 2022-05-04 2023-11-09 Massachusetts Institute Of Technology Formulations and medical devices for minimally-invasive deep tissue applications
CN115252810B (zh) * 2022-05-26 2025-06-27 安徽中医药大学 一种可变形态的喜树碱多肽纳米制剂及其制备方法和应用

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1006606A (en) 1961-05-12 1965-10-06 Fmc Corp Haemostatic wound dressing
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4272398A (en) 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4636208A (en) 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US4861627A (en) 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US5019646A (en) 1987-08-25 1991-05-28 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5843156A (en) 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US5126141A (en) 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
CA2122041A1 (en) 1989-12-04 1993-04-29 Kenneth Kensey Plug device for sealing openings and method of use
US5180375A (en) 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US5222974A (en) 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
JPH05204646A (ja) 1992-01-28 1993-08-13 Mitsubishi Electric Corp 知識処理システム
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5955343A (en) * 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
FR2715309B1 (fr) 1994-01-24 1996-08-02 Imedex Composition adhésive, à usage chirurgical, à base de collagène modifié par coupure oxydative et non réticulé.
US6413539B1 (en) 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
WO1996040033A1 (en) * 1995-06-07 1996-12-19 Clarion Pharmaceuticals Inc. Non-biological patch for hemostasis
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
ATE247494T1 (de) 1996-04-04 2003-09-15 Baxter Ag Blutstillender schwamm auf kollagenbasis
US6489446B1 (en) * 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
US6177609B1 (en) 1997-03-10 2001-01-23 Meadox Medicals, Inc. Self-aggregating protein compositions and use as sealants
US5906997A (en) 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US6368877B1 (en) 1997-06-25 2002-04-09 Massachusetts Institute Of Technology Self-assembling peptide surfaces for cell patterning and interactions
US6235340B1 (en) 1998-04-10 2001-05-22 Massachusetts Institute Of Technology Biopolymer-resistant coatings
JP4159682B2 (ja) 1998-12-22 2008-10-01 株式会社クラレ 止血材
US6333194B1 (en) * 1999-01-19 2001-12-25 The Children's Hospital Of Philadelphia Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
WO2000063079A1 (en) 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
JP4596341B2 (ja) 1999-11-11 2010-12-08 オリンパステルモバイオマテリアル株式会社 液体状創傷被覆材
US6844324B1 (en) 1999-11-12 2005-01-18 Massachusetts Institute Of Technology Modular peptide mediated intracellular delivery system and uses therefore
AU783689B2 (en) 2000-01-24 2005-11-24 Adnexus Therapeutics, Inc. Sensitive, multiplexed diagnostic assays for protein analysis
KR20030031480A (ko) 2000-04-28 2003-04-21 프지오메드, 인코포레이티드 폴리산 및 폴리알킬렌 옥사이드의 지혈 조성물 및 이들의이용 방법
US6953656B2 (en) 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of polypeptides
US6953659B2 (en) 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of nucleic acids
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
AR032517A1 (es) 2001-01-25 2003-11-12 Nycomed Pharma As Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno, y una esponja de colageno alargada
EP1367961B1 (en) 2001-02-06 2008-12-31 Massachusetts Institute Of Technology Peptide scaffold encapsulation of tissue cells and uses thereof
US7449180B2 (en) 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
JP3838882B2 (ja) 2001-02-28 2006-10-25 株式会社Ｐｈｇ 温度応答性材料およびそれを含む組成物
EP1402001A4 (en) 2001-05-04 2006-05-24 Scripps Research Inst ANTIMICROBIAL PEPTIDES AND COMPOSITIONS
IL159156A0 (en) 2001-06-22 2004-06-01 Millard Marsden Mershon A gel forming composition containing a polyacrylic acid
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
WO2003052117A2 (en) 2001-09-19 2003-06-26 Massachusetts Institute Of Technology Methods and products related to non-viral transfection
JP2003252936A (ja) 2002-02-28 2003-09-10 Sentomedo:Kk 温度応答性材料及びそれを含む組成物
AU2003222167A1 (en) 2002-04-02 2003-10-20 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
WO2003096972A2 (en) 2002-05-13 2003-11-27 Massachusetts Institute Of Technology Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof
CA2387257C (en) 2002-05-23 2009-07-28 Suncor Energy Inc. Static deaeration conditioner for processing of bitumen froth
GB0216286D0 (en) 2002-07-15 2002-08-21 Univ Leeds Network
EP1542709A2 (en) 2002-08-06 2005-06-22 EPIX Pharmaceuticals, Inc. Peptide aggregates
WO2004110964A2 (en) 2003-06-16 2004-12-23 Nuevolution A/S Encoded molecules by translation (emt)
US7713923B2 (en) 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
DK1636250T3 (en) * 2003-06-25 2016-02-22 Massachusetts Inst Technology SELF-ORGANIZING PEPTIDES, CONTAINING MODIFICATIONS, AND APPLICATIONS THEREOF
ES2564044T3 (es) * 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
JP2005074079A (ja) 2003-09-02 2005-03-24 Masao Tanihara 止血材
US7846891B2 (en) * 2003-10-17 2010-12-07 Massachusetts Institute Of Technology Self-assembling peptides for regeneration and repair of neural tissue
US20050266086A1 (en) * 2004-06-01 2005-12-01 Sawhney Amarpreet S Intrauterine applications of materials formed in situ
EP3031466B1 (en) 2004-07-06 2018-11-28 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
US7884185B2 (en) 2004-07-28 2011-02-08 University Of Delaware Hydrogels and uses thereof
US8039258B2 (en) 2004-09-28 2011-10-18 Ethicon, Inc. Tissue-engineering scaffolds containing self-assembled-peptide hydrogels
WO2006047315A2 (en) 2004-10-25 2006-05-04 The Brigham And Women's Hospital, Inc. Targeted delivery of biological factors using self-assembling peptide nanofibers
CA2592292A1 (en) 2005-01-04 2006-07-13 The Brigham And Women's Hospital, Inc. Sustained delivery of pdgf using self-assembling peptide nanofibers
ES2427565T3 (es) 2005-04-25 2013-10-31 Massachusetts Institute Of Technology Péptidos autoensambladores para promover la hemostasia
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
HUE037994T2 (hu) 2006-04-25 2018-09-28 Massachusetts Inst Technology Készítmények és eljárások szennyezõ anyagok, testfolyadékok vagy más anyagok mozgásának befolyásolására és/vagy más fiziológiai állapotok befolyásolására
US8021570B2 (en) 2006-06-13 2011-09-20 Wisconsin Alumni Research Foundation β-peptide lyotropic liquid crystals and methods of manufacture and use thereof
JP5496671B2 (ja) 2006-09-26 2014-05-21 マサチューセッツ インスティテュート オブ テクノロジー 修飾自己組織化ペプチド
EP2146733B1 (en) 2007-03-14 2020-11-25 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
US20120085262A1 (en) 2010-08-26 2012-04-12 Freudenberg Forschungsdienste Kg Production of Highly Concentrated Solutions of Self-Assembling Proteins
KR20140123597A (ko) 2012-02-22 2014-10-22 노쓰웨스턴유니버시티 암 및 기타 상태의 치료를 위한 나노구조체

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123375A1 (ko) * 2013-02-06 2014-08-14 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도
KR101432276B1 (ko) * 2013-02-06 2014-08-21 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도

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