KR20060120644A - 술폰아미드 함유 인돌 화합물의 결정 및 그 제조방법 - Google Patents

술폰아미드 함유 인돌 화합물의 결정 및 그 제조방법 Download PDF

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Publication number
KR20060120644A
KR20060120644A KR1020067004877A KR20067004877A KR20060120644A KR 20060120644 A KR20060120644 A KR 20060120644A KR 1020067004877 A KR1020067004877 A KR 1020067004877A KR 20067004877 A KR20067004877 A KR 20067004877A KR 20060120644 A KR20060120644 A KR 20060120644A
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KR
South Korea
Prior art keywords
crystal
methyl
cyano
indol
cyanobenzenesulfonamide
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Ceased
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KR1020067004877A
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English (en)
Korean (ko)
Inventor
케이코 타카하시
켄지 하야시
타이치 아베
타카오 오마에
타카시 카토
Original Assignee
에자이 가부시키가이샤
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Publication date
Application filed by 에자이 가부시키가이샤 filed Critical 에자이 가부시키가이샤
Publication of KR20060120644A publication Critical patent/KR20060120644A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020067004877A 2003-09-10 2004-09-01 술폰아미드 함유 인돌 화합물의 결정 및 그 제조방법 Ceased KR20060120644A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003318953 2003-09-10
JPJP-P-2003-00318953 2003-09-10

Publications (1)

Publication Number Publication Date
KR20060120644A true KR20060120644A (ko) 2006-11-27

Family

ID=34308544

Family Applications (1)

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KR1020067004877A Ceased KR20060120644A (ko) 2003-09-10 2004-09-01 술폰아미드 함유 인돌 화합물의 결정 및 그 제조방법

Country Status (24)

Country Link
US (2) US7754894B2 (enExample)
EP (1) EP1666463B1 (enExample)
JP (1) JP4435090B2 (enExample)
KR (1) KR20060120644A (enExample)
CN (2) CN101165049A (enExample)
AT (1) ATE486849T1 (enExample)
AU (1) AU2004272400B2 (enExample)
BR (1) BRPI0414314A (enExample)
CA (1) CA2536995C (enExample)
CY (1) CY1110975T1 (enExample)
DE (1) DE602004029907D1 (enExample)
DK (1) DK1666463T3 (enExample)
ES (1) ES2354286T3 (enExample)
HR (1) HRP20100631T1 (enExample)
IL (2) IL174059A0 (enExample)
MX (1) MXPA06002732A (enExample)
NO (1) NO335256B1 (enExample)
NZ (1) NZ546111A (enExample)
PL (1) PL1666463T3 (enExample)
PT (1) PT1666463E (enExample)
RU (1) RU2336269C2 (enExample)
SI (1) SI1666463T1 (enExample)
TW (1) TW200514770A (enExample)
WO (1) WO2005026118A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005026118A1 (ja) * 2003-09-10 2005-03-24 Eisai Co., Ltd. スルホンアミド含有インドール化合物の結晶およびその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3868534B2 (ja) * 1996-05-24 2007-01-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド誘導体の製造法および中間体
JP2000247949A (ja) * 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
ES2341843T3 (es) * 2000-02-03 2010-06-29 EISAI R&D MANAGEMENT CO., LTD. Inhibidores de la expresion de integrina.
TWI283575B (en) 2000-10-31 2007-07-11 Eisai Co Ltd Medicinal compositions for concomitant use as anticancer agent
WO2005026118A1 (ja) * 2003-09-10 2005-03-24 Eisai Co., Ltd. スルホンアミド含有インドール化合物の結晶およびその製造方法

Also Published As

Publication number Publication date
WO2005026118A1 (ja) 2005-03-24
CN100406440C (zh) 2008-07-30
DK1666463T3 (da) 2010-12-20
TWI349663B (enExample) 2011-10-01
CY1110975T1 (el) 2015-06-11
NO20061545L (no) 2006-06-09
EP1666463B1 (en) 2010-11-03
HRP20100631T1 (hr) 2010-12-31
CA2536995C (en) 2013-12-17
EP1666463A1 (en) 2006-06-07
TW200514770A (en) 2005-05-01
AU2004272400A1 (en) 2005-03-24
ATE486849T1 (de) 2010-11-15
PL1666463T3 (pl) 2011-04-29
BRPI0414314A (pt) 2006-10-31
NO335256B1 (no) 2014-10-27
RU2006111454A (ru) 2006-08-27
JPWO2005026118A1 (ja) 2007-11-08
DE602004029907D1 (de) 2010-12-16
PT1666463E (pt) 2011-01-17
IL174059A0 (en) 2006-08-01
US7754894B2 (en) 2010-07-13
US20090247768A1 (en) 2009-10-01
AU2004272400B2 (en) 2010-03-04
US20070082941A1 (en) 2007-04-12
CN1849305A (zh) 2006-10-18
IL196569A0 (en) 2011-07-31
EP1666463A4 (en) 2007-12-12
HK1092796A1 (en) 2007-02-16
MXPA06002732A (es) 2006-06-05
CA2536995A1 (en) 2005-03-24
NZ546111A (en) 2008-11-28
JP4435090B2 (ja) 2010-03-17
CN101165049A (zh) 2008-04-23
SI1666463T1 (sl) 2011-02-28
ES2354286T3 (es) 2011-03-11
RU2336269C2 (ru) 2008-10-20

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