CY1110975T1 - Κρυσταλλος ενωσεως ινδολης περιεχουσης σουλφοναμιδιο και μεθοδος παραγωγης του - Google Patents

Κρυσταλλος ενωσεως ινδολης περιεχουσης σουλφοναμιδιο και μεθοδος παραγωγης του

Info

Publication number
CY1110975T1
CY1110975T1 CY20101101136T CY101101136T CY1110975T1 CY 1110975 T1 CY1110975 T1 CY 1110975T1 CY 20101101136 T CY20101101136 T CY 20101101136T CY 101101136 T CY101101136 T CY 101101136T CY 1110975 T1 CY1110975 T1 CY 1110975T1
Authority
CY
Cyprus
Prior art keywords
crystall
united
industry
production
sulfonamide
Prior art date
Application number
CY20101101136T
Other languages
English (en)
Inventor
Keiko Takahashi
Kenji Hayashi
Taichi Abe
Takao Omae
Takashi Kato
Original Assignee
Eisai R&D Management Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co., Ltd filed Critical Eisai R&D Management Co., Ltd
Publication of CY1110975T1 publication Critical patent/CY1110975T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Κρυσταλλική μορφή του Ν-(3-κυανιο-4-μεθυλ-1Η-ινδολ-7-υλ)-3-κυανιοβενζολιοσουλφοναμιδίου έχουσα κορυφή περιθλάσεως σε γωνία περιθλάσεως (2Θ ± 0.2°) ίση με 19,1° σε μία περίθλαση ακτίνων Χ κόνεως.
CY20101101136T 2003-09-10 2010-12-10 Κρυσταλλος ενωσεως ινδολης περιεχουσης σουλφοναμιδιο και μεθοδος παραγωγης του CY1110975T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003318953 2003-09-10
EP04772605A EP1666463B1 (en) 2003-09-10 2004-09-01 Crystal of sulfonamide-containing indole compound and process for producing the same

Publications (1)

Publication Number Publication Date
CY1110975T1 true CY1110975T1 (el) 2015-06-11

Family

ID=34308544

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101101136T CY1110975T1 (el) 2003-09-10 2010-12-10 Κρυσταλλος ενωσεως ινδολης περιεχουσης σουλφοναμιδιο και μεθοδος παραγωγης του

Country Status (25)

Country Link
US (2) US7754894B2 (el)
EP (1) EP1666463B1 (el)
JP (1) JP4435090B2 (el)
KR (1) KR20060120644A (el)
CN (2) CN101165049A (el)
AT (1) ATE486849T1 (el)
AU (1) AU2004272400B2 (el)
BR (1) BRPI0414314A (el)
CA (1) CA2536995C (el)
CY (1) CY1110975T1 (el)
DE (1) DE602004029907D1 (el)
DK (1) DK1666463T3 (el)
ES (1) ES2354286T3 (el)
HK (1) HK1092796A1 (el)
HR (1) HRP20100631T1 (el)
IL (2) IL174059A0 (el)
MX (1) MXPA06002732A (el)
NO (1) NO335256B1 (el)
NZ (1) NZ546111A (el)
PL (1) PL1666463T3 (el)
PT (1) PT1666463E (el)
RU (1) RU2336269C2 (el)
SI (1) SI1666463T1 (el)
TW (1) TW200514770A (el)
WO (1) WO2005026118A1 (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004029907D1 (de) * 2003-09-10 2010-12-16 Eisai R&D Man Co Ltd Kristall einer sulfonamidhaltigen indolverbindung und verfahren zu dessen herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3868534B2 (ja) * 1996-05-24 2007-01-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド誘導体の製造法および中間体
JP2000247949A (ja) * 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
JP4039856B2 (ja) * 2000-02-03 2008-01-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 インテグリン発現阻害剤
TWI283575B (en) * 2000-10-31 2007-07-11 Eisai Co Ltd Medicinal compositions for concomitant use as anticancer agent
DE602004029907D1 (de) * 2003-09-10 2010-12-16 Eisai R&D Man Co Ltd Kristall einer sulfonamidhaltigen indolverbindung und verfahren zu dessen herstellung

Also Published As

Publication number Publication date
EP1666463A4 (en) 2007-12-12
JPWO2005026118A1 (ja) 2007-11-08
AU2004272400A1 (en) 2005-03-24
SI1666463T1 (sl) 2011-02-28
MXPA06002732A (es) 2006-06-05
PT1666463E (pt) 2011-01-17
PL1666463T3 (pl) 2011-04-29
BRPI0414314A (pt) 2006-10-31
IL196569A0 (en) 2011-07-31
ATE486849T1 (de) 2010-11-15
NZ546111A (en) 2008-11-28
KR20060120644A (ko) 2006-11-27
ES2354286T3 (es) 2011-03-11
US20090247768A1 (en) 2009-10-01
US20070082941A1 (en) 2007-04-12
HK1092796A1 (en) 2007-02-16
DK1666463T3 (da) 2010-12-20
CA2536995A1 (en) 2005-03-24
CN100406440C (zh) 2008-07-30
DE602004029907D1 (de) 2010-12-16
US7754894B2 (en) 2010-07-13
TWI349663B (el) 2011-10-01
WO2005026118A1 (ja) 2005-03-24
CA2536995C (en) 2013-12-17
IL174059A0 (en) 2006-08-01
EP1666463B1 (en) 2010-11-03
HRP20100631T1 (hr) 2010-12-31
NO335256B1 (no) 2014-10-27
CN101165049A (zh) 2008-04-23
NO20061545L (no) 2006-06-09
AU2004272400B2 (en) 2010-03-04
RU2336269C2 (ru) 2008-10-20
CN1849305A (zh) 2006-10-18
EP1666463A1 (en) 2006-06-07
RU2006111454A (ru) 2006-08-27
TW200514770A (en) 2005-05-01
JP4435090B2 (ja) 2010-03-17

Similar Documents

Publication Publication Date Title
NO2020010I1 (no) fostamatinib eller et farmasøytisk akseptabelt salt av fostamatinib, eller et hydrat, solvat eller N-oksid av fostamatinib eller det farmasøytisk akseptable saltet av fostamatinib, spesielt fostamatinib dinatrium, eventuelt på form av et hydrat
CY2016013I1 (el) Φαρμακευτικες συνθεσεις που περιλαμβανουν βαλσαρτανη και αναστολεις nep
CY1106425T1 (el) Ενωσις βενζυλαμινης και φαρμακευτικη χρησις αυτης
CY1112916T1 (el) 3-ζ-1-(4-(ν-((4-μεθυλ-πιπεραζιν-1-υλ)-μεθυλκαρβονυλ)-ν-μεθυλ-αμινο)-ανιλινο)-1-φαινυλ-μεθυλενο-6-μεθοξυκαρβονυλ-2-ινδολινονη-μονοαιθανοσουλφονικη και η χρηση αυτης ως φαρμακευτικη συνθεση
CY1108725T1 (el) Συνδυασμος ανταγωνιστου-nmda και αναστολεων ακετυλοχολινεστερασης δια την θεραπειαν της νοσου alzheimer
CY1112938T1 (el) Παραγωγα n-φαινυλ-2-πυριμιδινης-αμινης
DE60217363D1 (de) 17beta-hydroxysteroid dehydrogenase type 3 inhibitoren zur behandlung von androgen-abhängigen erkrankungen
ATE502596T1 (de) Schmales zahnimplantat und zugeordnete teile
HK1145628A1 (en) Pharmaceutical compositions having an analgesic effect and containing 1- benzyl-1-hydroxy-2, 3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino propionic acid amides or related compounds
FR2853631B1 (fr) Materiau d'emballage et procede pour sa production
PT1465864E (pt) Inibidores de factor xa e outras serina proteases envolvidos na cascata da coagulacao
WO2005038523A3 (en) Imprint lithography templates having alignment marks
CY1107913T1 (el) Πολυμορφικες και αλλες κρυσταλλικες μορφες cis-ftc
ATE458465T1 (de) Kosmetische und/oder dermatologische zusammensetzung mit bornitrid
DE602004019795D1 (de) Kombination aus n-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-ä1,3,4-oxadiazol-2-ylüphenyl)pyridin-3-sulfonamid und einem biphosphonat
CY1107696T1 (el) Συνδιασμος εταβονικης λοτεπρεδνολης και dfho για την αντιμετωπιση αναπνευστικων παθησεων, αλλεργικων παθησεων, ασθματος και copd
BRPI0614533A2 (pt) composição cosmética destinada à proteção e/ou à reparação dos materiais queratínicos, composto, processo de síntese de uma polilisina de cadeia graxa, e, utilização de uma composição cosmética
NO20062599L (no) Fremgangsmate for syntese av perindopril og farmasoytisk akseptable salter derav
DE50210584D1 (de) Sichter zum Sichten von körnigem Gut
CY1110975T1 (el) Κρυσταλλος ενωσεως ινδολης περιεχουσης σουλφοναμιδιο και μεθοδος παραγωγης του
FR2840799B1 (fr) Vis d'osteosynthese
DE60228183D1 (de) Fotopolymerisierbare Zusammensetzung und Aufzeichnungsmaterial
CY1106543T1 (el) Μεθοδος συνθεσεως υπερινδοπριλης και τα φαρμακευτικως αποδεκτα αλατα αυτης
ITBO20020034A1 (it) Macchina per la realizzazione di confezioni cosiddette "strip"
PL379628A1 (pl) Nowy sposób syntezy perindoprilu i jego farmaceutycznie dopuszczalnych soli