IL174059A0 - Crystalline sulfonamide-containing indole compound and process for preparing the same - Google Patents
Crystalline sulfonamide-containing indole compound and process for preparing the sameInfo
- Publication number
- IL174059A0 IL174059A0 IL174059A IL17405906A IL174059A0 IL 174059 A0 IL174059 A0 IL 174059A0 IL 174059 A IL174059 A IL 174059A IL 17405906 A IL17405906 A IL 17405906A IL 174059 A0 IL174059 A0 IL 174059A0
- Authority
- IL
- Israel
- Prior art keywords
- preparing
- same
- indole compound
- containing indole
- crystalline
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- -1 indole compound Chemical class 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- LWGUASZLXHYWIV-UHFFFAOYSA-N 3-cyano-n-(3-cyano-4-methyl-1h-indol-7-yl)benzenesulfonamide Chemical compound C1=2NC=C(C#N)C=2C(C)=CC=C1NS(=O)(=O)C1=CC=CC(C#N)=C1 LWGUASZLXHYWIV-UHFFFAOYSA-N 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003318953 | 2003-09-10 | ||
| PCT/JP2004/012649 WO2005026118A1 (ja) | 2003-09-10 | 2004-09-01 | スルホンアミド含有インドール化合物の結晶およびその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL174059A0 true IL174059A0 (en) | 2006-08-01 |
Family
ID=34308544
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL174059A IL174059A0 (en) | 2003-09-10 | 2006-03-02 | Crystalline sulfonamide-containing indole compound and process for preparing the same |
| IL196569A IL196569A0 (en) | 2003-09-10 | 2009-01-18 | Process for preparing crystalline sulfonamide-containing indole compound |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL196569A IL196569A0 (en) | 2003-09-10 | 2009-01-18 | Process for preparing crystalline sulfonamide-containing indole compound |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7754894B2 (enExample) |
| EP (1) | EP1666463B1 (enExample) |
| JP (1) | JP4435090B2 (enExample) |
| KR (1) | KR20060120644A (enExample) |
| CN (2) | CN101165049A (enExample) |
| AT (1) | ATE486849T1 (enExample) |
| AU (1) | AU2004272400B2 (enExample) |
| BR (1) | BRPI0414314A (enExample) |
| CA (1) | CA2536995C (enExample) |
| CY (1) | CY1110975T1 (enExample) |
| DE (1) | DE602004029907D1 (enExample) |
| DK (1) | DK1666463T3 (enExample) |
| ES (1) | ES2354286T3 (enExample) |
| HR (1) | HRP20100631T1 (enExample) |
| IL (2) | IL174059A0 (enExample) |
| MX (1) | MXPA06002732A (enExample) |
| NO (1) | NO335256B1 (enExample) |
| NZ (1) | NZ546111A (enExample) |
| PL (1) | PL1666463T3 (enExample) |
| PT (1) | PT1666463E (enExample) |
| RU (1) | RU2336269C2 (enExample) |
| SI (1) | SI1666463T1 (enExample) |
| TW (1) | TW200514770A (enExample) |
| WO (1) | WO2005026118A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005026118A1 (ja) * | 2003-09-10 | 2005-03-24 | Eisai Co., Ltd. | スルホンアミド含有インドール化合物の結晶およびその製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3868534B2 (ja) * | 1996-05-24 | 2007-01-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド誘導体の製造法および中間体 |
| JP2000247949A (ja) * | 1999-02-26 | 2000-09-12 | Eisai Co Ltd | スルホンアミド含有インドール化合物 |
| ES2341843T3 (es) * | 2000-02-03 | 2010-06-29 | EISAI R&D MANAGEMENT CO., LTD. | Inhibidores de la expresion de integrina. |
| TWI283575B (en) | 2000-10-31 | 2007-07-11 | Eisai Co Ltd | Medicinal compositions for concomitant use as anticancer agent |
| WO2005026118A1 (ja) * | 2003-09-10 | 2005-03-24 | Eisai Co., Ltd. | スルホンアミド含有インドール化合物の結晶およびその製造方法 |
-
2004
- 2004-09-01 WO PCT/JP2004/012649 patent/WO2005026118A1/ja not_active Ceased
- 2004-09-01 PT PT04772605T patent/PT1666463E/pt unknown
- 2004-09-01 DE DE602004029907T patent/DE602004029907D1/de not_active Expired - Lifetime
- 2004-09-01 PL PL04772605T patent/PL1666463T3/pl unknown
- 2004-09-01 BR BRPI0414314-0A patent/BRPI0414314A/pt not_active IP Right Cessation
- 2004-09-01 DK DK04772605.4T patent/DK1666463T3/da active
- 2004-09-01 CN CNA2007101667949A patent/CN101165049A/zh active Pending
- 2004-09-01 EP EP04772605A patent/EP1666463B1/en not_active Expired - Lifetime
- 2004-09-01 CN CNB2004800260696A patent/CN100406440C/zh not_active Expired - Fee Related
- 2004-09-01 NZ NZ546111A patent/NZ546111A/en not_active IP Right Cessation
- 2004-09-01 ES ES04772605T patent/ES2354286T3/es not_active Expired - Lifetime
- 2004-09-01 MX MXPA06002732A patent/MXPA06002732A/es active IP Right Grant
- 2004-09-01 AT AT04772605T patent/ATE486849T1/de active
- 2004-09-01 CA CA2536995A patent/CA2536995C/en not_active Expired - Fee Related
- 2004-09-01 SI SI200431578T patent/SI1666463T1/sl unknown
- 2004-09-01 KR KR1020067004877A patent/KR20060120644A/ko not_active Ceased
- 2004-09-01 US US10/571,279 patent/US7754894B2/en not_active Expired - Lifetime
- 2004-09-01 HR HR20100631T patent/HRP20100631T1/hr unknown
- 2004-09-01 RU RU2006111454/04A patent/RU2336269C2/ru not_active IP Right Cessation
- 2004-09-01 JP JP2005513843A patent/JP4435090B2/ja not_active Expired - Fee Related
- 2004-09-01 AU AU2004272400A patent/AU2004272400B2/en not_active Ceased
- 2004-09-06 TW TW093126889A patent/TW200514770A/zh not_active IP Right Cessation
-
2006
- 2006-03-02 IL IL174059A patent/IL174059A0/en not_active IP Right Cessation
- 2006-04-05 NO NO20061545A patent/NO335256B1/no not_active IP Right Cessation
-
2009
- 2009-01-18 IL IL196569A patent/IL196569A0/en unknown
- 2009-06-09 US US12/480,959 patent/US20090247768A1/en not_active Abandoned
-
2010
- 2010-12-10 CY CY20101101136T patent/CY1110975T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |