KR102545649B1 - 염 약물의 염 약물에서 중성 약물으로의 제자리 전환에 의한 저용해도 또는 불안정한 이온화되지 않은 중성 약물의 경피성 제제 및 전달 방법 - Google Patents

염 약물의 염 약물에서 중성 약물으로의 제자리 전환에 의한 저용해도 또는 불안정한 이온화되지 않은 중성 약물의 경피성 제제 및 전달 방법 Download PDF

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KR102545649B1
KR102545649B1 KR1020227018732A KR20227018732A KR102545649B1 KR 102545649 B1 KR102545649 B1 KR 102545649B1 KR 1020227018732 A KR1020227018732 A KR 1020227018732A KR 20227018732 A KR20227018732 A KR 20227018732A KR 102545649 B1 KR102545649 B1 KR 102545649B1
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drug reservoir
active agent
drug
layer
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KR20220082928A (ko
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은 수 이
아미트 케이. 제인
파르민데르 싱
아팔라 사기
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코리움, 엘엘씨
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227018732A 2016-07-27 2017-07-26 염 약물의 염 약물에서 중성 약물으로의 제자리 전환에 의한 저용해도 또는 불안정한 이온화되지 않은 중성 약물의 경피성 제제 및 전달 방법 Active KR102545649B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237020230A KR20230098349A (ko) 2016-07-27 2017-07-26 염 약물의 염 약물에서 중성 약물으로의 제자리 전환에 의한 저용해도 또는 불안정한 이온화되지 않은 중성 약물의 경피성 제제 및 전달 방법

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US201662367502P 2016-07-27 2016-07-27
US201662367542P 2016-07-27 2016-07-27
US62/367,542 2016-07-27
US62/367,502 2016-07-27
US201662423133P 2016-11-16 2016-11-16
US62/423,133 2016-11-16
US201762444763P 2017-01-10 2017-01-10
US201762444745P 2017-01-10 2017-01-10
US62/444,745 2017-01-10
US62/444,763 2017-01-10
US201762457794P 2017-02-10 2017-02-10
US62/457,794 2017-02-10
US201762504408P 2017-05-10 2017-05-10
US201762504391P 2017-05-10 2017-05-10
US62/504,408 2017-05-10
US62/504,391 2017-05-10
KR1020197005737A KR102406482B1 (ko) 2016-07-27 2017-07-26 염 약물의 염 약물에서 중성 약물으로의 제자리 전환에 의한 저용해도 또는 불안정한 이온화되지 않은 중성 약물의 경피성 제제 및 전달 방법
PCT/US2017/044048 WO2018022815A2 (en) 2016-07-27 2017-07-26 Transdermal formulation and delivery method of low solubility or unstable unionized neutral drugs by in situ salt-to-neutral drug conversion of salt drug

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