KR102517112B1 - 인간화 IL-4 및 IL-4Rα 동물 - Google Patents
인간화 IL-4 및 IL-4Rα 동물 Download PDFInfo
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| JP7048051B2 (ja) | 2018-07-11 | 2022-04-05 | 正徳 染井 | 痒みを軽減するアトピー性皮膚炎治療剤 |
| IL315703A (en) | 2018-07-16 | 2024-11-01 | Regeneron Pharma | Non-human animal models of DITRA disease and their uses |
| WO2020074005A1 (en) * | 2018-10-12 | 2020-04-16 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric genes |
| WO2020147829A1 (zh) * | 2019-01-17 | 2020-07-23 | 北京百奥赛图基因生物技术有限公司 | 人源化转基因动物 |
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| CN112300265B (zh) * | 2019-07-29 | 2022-09-27 | 百奥赛图(北京)医药科技股份有限公司 | Il33基因人源化的非人动物的构建方法和应用 |
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| WO2021129766A1 (zh) * | 2019-12-25 | 2021-07-01 | 江苏集萃药康生物科技股份有限公司 | 一种il-15人源化小鼠模型及其用途 |
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| CN113527485B (zh) | 2020-04-17 | 2024-11-15 | 湖南麦济生物技术股份有限公司 | 抗人白细胞介素-4受体α抗体及其制备方法和应用 |
| CN111808882B (zh) * | 2020-09-01 | 2020-12-29 | 北京百奥赛图基因生物技术有限公司 | Il7r基因人源化改造的动物模型的构建方法及其应用 |
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