KR102463973B1 - ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법 - Google Patents

ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법 Download PDF

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KR102463973B1
KR102463973B1 KR1020217026982A KR20217026982A KR102463973B1 KR 102463973 B1 KR102463973 B1 KR 102463973B1 KR 1020217026982 A KR1020217026982 A KR 1020217026982A KR 20217026982 A KR20217026982 A KR 20217026982A KR 102463973 B1 KR102463973 B1 KR 102463973B1
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delete delete
rnai agent
nucleotides
strand
stranded rnai
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KR20210110397A (ko
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알피카 세갈
클라우스 채리스
브라이언 베텐코트
마틴 마이어
칼란토타틸 지. 라지브
그레고리 힌클
무티아 마노하란
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알닐람 파마슈티칼스 인코포레이티드
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KR1020217026982A 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법 Active KR102463973B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227038298A KR20220154244A (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201361826125P 2013-05-22 2013-05-22
US61/826,125 2013-05-22
US201361898695P 2013-11-01 2013-11-01
US61/898,695 2013-11-01
US201461979727P 2014-04-15 2014-04-15
US61/979,727 2014-04-15
US201461989028P 2014-05-06 2014-05-06
US61/989,028 2014-05-06
PCT/US2014/039109 WO2014190137A1 (en) 2013-05-22 2014-05-22 SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
KR1020157036053A KR102295648B1 (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법

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KR1020227038298A Division KR20220154244A (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법

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KR20210110397A KR20210110397A (ko) 2021-09-07
KR102463973B1 true KR102463973B1 (ko) 2022-11-07

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KR1020217026982A Active KR102463973B1 (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법
KR1020227038298A Withdrawn KR20220154244A (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법
KR1020157036053A Expired - Fee Related KR102295648B1 (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법

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KR1020227038298A Withdrawn KR20220154244A (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법
KR1020157036053A Expired - Fee Related KR102295648B1 (ko) 2013-05-22 2014-05-22 ＳＥＲＰＩＮＡ1 ｉＲＮＡ 조성물 및 이의 사용 방법

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US (5) US9574192B2 (https=)
EP (2) EP3412774A1 (https=)
JP (3) JP6495250B2 (https=)
KR (3) KR102463973B1 (https=)
CN (2) CN113018307A (https=)
AU (2) AU2014268509B2 (https=)
BR (1) BR112015029139B1 (https=)
CA (1) CA2912826A1 (https=)
CL (1) CL2015003441A1 (https=)
CY (1) CY1122159T1 (https=)
DK (1) DK2999785T3 (https=)
DO (1) DOP2015000288A (https=)
EA (1) EA038792B1 (https=)
ES (1) ES2676146T3 (https=)
GT (1) GT201500330A (https=)
HR (1) HRP20181030T1 (https=)
HU (1) HUE038146T2 (https=)
IL (3) IL242637B (https=)
LT (1) LT2999785T (https=)
MX (2) MX379208B (https=)
MY (1) MY176712A (https=)
PE (2) PE20210921A1 (https=)
PL (1) PL2999785T3 (https=)
PT (1) PT2999785T (https=)
RS (1) RS57418B1 (https=)
RU (1) RU2015154721A (https=)
SG (3) SG10201804472YA (https=)
SI (1) SI2999785T1 (https=)
SM (1) SMT201800403T1 (https=)
TW (2) TW201936624A (https=)
UY (2) UY35582A (https=)
WO (1) WO2014190137A1 (https=)
ZA (1) ZA201509252B (https=)

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DK3444350T3 (da) 2013-07-03 2022-02-07 Dicerna Pharmaceuticals Inc Fremgangsmåder og sammensætninger til specifik hæmning af alpha-1 antitrypsin ved dobbeltstrenget rna
CA3215908A1 (en) 2014-05-22 2015-11-26 Alnylam Pharmaceuticals, Inc. Angiotensinogen (agt) irna compositions and methods of use thereof
TW201620526A (zh) * 2014-06-17 2016-06-16 愛羅海德研究公司 用於抑制α－１抗胰蛋白酶基因表現之組合物及方法
IL316808A (en) 2014-08-20 2025-01-01 Alnylam Pharmaceuticals Inc Modified double-stranded RNA materials and their uses
AU2015311704B2 (en) 2014-09-07 2021-12-09 Selecta Biosciences, Inc. Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses
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KR102827366B1 (ko) * 2015-05-06 2025-07-03 알닐람 파마슈티칼스 인코포레이티드 인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법
FI3386518T3 (fi) 2015-12-07 2025-09-25 Genzyme Corp Menetelmiä ja koostumuksia serpinc1:een liittyvän häiriön hoitamiseksi
US10876116B2 (en) * 2016-07-15 2020-12-29 The Board Of Regents Of The University Of Oklahoma Anti-ARID3a treatments for inflammatory disorders
TW202313978A (zh) 2016-11-23 2023-04-01 美商阿尼拉製藥公司 絲胺酸蛋白酶抑制因子Ａ１ ｉＲＮＡ組成物及其使用方法
KR102645243B1 (ko) * 2016-11-23 2024-03-11 알닐람 파마슈티칼스 인코포레이티드 표적외 효과가 감소된 변형 rna 작용제
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