KR101993254B1 - 태반 줄기 세포를 사용한 혈관신생 - Google Patents
태반 줄기 세포를 사용한 혈관신생 Download PDFInfo
- Publication number
- KR101993254B1 KR101993254B1 KR1020127029076A KR20127029076A KR101993254B1 KR 101993254 B1 KR101993254 B1 KR 101993254B1 KR 1020127029076 A KR1020127029076 A KR 1020127029076A KR 20127029076 A KR20127029076 A KR 20127029076A KR 101993254 B1 KR101993254 B1 KR 101993254B1
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- KR
- South Korea
- Prior art keywords
- cells
- isolated
- placental
- placental cells
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Botany (AREA)
- Transplantation (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pregnancy & Childbirth (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32182210P | 2010-04-07 | 2010-04-07 | |
| US61/321,822 | 2010-04-07 | ||
| PCT/US2011/031335 WO2011127117A1 (en) | 2010-04-07 | 2011-04-06 | Angiogenesis using placental stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197017761A Division KR20190076060A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20130100053A KR20130100053A (ko) | 2013-09-09 |
| KR101993254B1 true KR101993254B1 (ko) | 2019-06-26 |
Family
ID=44761079
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127029076A Expired - Fee Related KR101993254B1 (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020207012469A Ceased KR20200047797A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020217007036A Ceased KR20210029310A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020197017761A Ceased KR20190076060A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020227001782A Ceased KR20220015489A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020237012529A Ceased KR20230054905A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020247018667A Withdrawn KR20240096688A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207012469A Ceased KR20200047797A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020217007036A Ceased KR20210029310A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020197017761A Ceased KR20190076060A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020227001782A Ceased KR20220015489A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020237012529A Ceased KR20230054905A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
| KR1020247018667A Withdrawn KR20240096688A (ko) | 2010-04-07 | 2011-04-06 | 태반 줄기 세포를 사용한 혈관신생 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US9254302B2 (enExample) |
| EP (2) | EP3088512B1 (enExample) |
| JP (5) | JP6097684B2 (enExample) |
| KR (7) | KR101993254B1 (enExample) |
| CN (2) | CN107699541A (enExample) |
| AR (2) | AR081166A1 (enExample) |
| AU (1) | AU2011237747B2 (enExample) |
| CA (1) | CA2795518C (enExample) |
| CY (1) | CY1118105T1 (enExample) |
| DK (2) | DK2556145T3 (enExample) |
| ES (1) | ES2602474T3 (enExample) |
| HR (1) | HRP20161350T1 (enExample) |
| HU (1) | HUE029144T2 (enExample) |
| IL (2) | IL250234B2 (enExample) |
| LT (1) | LT2556145T (enExample) |
| MX (3) | MX337172B (enExample) |
| NZ (2) | NZ602808A (enExample) |
| PL (1) | PL2556145T3 (enExample) |
| PT (1) | PT2556145T (enExample) |
| RS (1) | RS55287B1 (enExample) |
| SI (1) | SI2556145T1 (enExample) |
| SM (1) | SMT201600377B (enExample) |
| TW (5) | TW201703777A (enExample) |
| WO (1) | WO2011127117A1 (enExample) |
| ZA (1) | ZA201606733B (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002046373A1 (en) | 2000-12-06 | 2002-06-13 | Hariri Robert J | Method of collecting placental stem cells |
| NZ528035A (en) | 2001-02-14 | 2005-07-29 | Robert J Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| US9119899B2 (en) * | 2006-01-18 | 2015-09-01 | Cormatrix Cardiovascular, Inc. | Method and system for treatment of cardiovascular disorders |
| NZ597304A (en) | 2005-10-13 | 2013-06-28 | Anthrogenesis Corp | Immunomodulation using placental stem cells |
| DK2471904T3 (en) | 2005-12-29 | 2019-02-18 | Celularity Inc | Placenta stem cell populations |
| CN101688177A (zh) | 2007-02-12 | 2010-03-31 | 人类起源公司 | 来自贴壁胎盘干细胞的肝细胞和软骨细胞;以及cd34+、cd45-胎盘干细胞富集的细胞群 |
| US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
| AU2008307633C1 (en) | 2007-09-28 | 2015-04-30 | Celularity Inc. | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| MX339624B (es) | 2008-08-20 | 2016-06-02 | Anthrogenesis Corp | Composiciones mejoradas de celulas y metodos para preparar las mismas. |
| EP2331109B1 (en) | 2008-08-22 | 2013-05-29 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| MX353489B (es) | 2009-07-02 | 2018-01-16 | Anthrogenesis Corp | Metodo para producir eritrocitos sin celulas alimentadoras. |
| DK3284818T3 (da) | 2010-01-26 | 2022-06-20 | Celularity Inc | Behandling af knoglerelateret kræft ved hjælp af placenta stamceller |
| TW201703777A (zh) * | 2010-04-07 | 2017-02-01 | 安瑟吉納西斯公司 | 利用胎盤幹細胞之血管新生 |
| NZ602798A (en) | 2010-04-08 | 2014-10-31 | Anthrogenesis Corp | Treatment of sarcoidosis using placental stem cells |
| WO2012009422A1 (en) | 2010-07-13 | 2012-01-19 | Anthrogenesis Corporation | Methods of generating natural killer cells |
| AR093183A1 (es) | 2010-12-31 | 2015-05-27 | Anthrogenesis Corp | Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras |
| US20120264215A1 (en) * | 2011-04-18 | 2012-10-18 | Korea University Research And Business Foudation Of Korea University | Placenta-derived cell-conditioned culture media and animal-free, feeder-free method for culturing stem cells using the same |
| CN104220081A (zh) | 2011-06-01 | 2014-12-17 | 人类起源公司 | 利用胎盘干细胞治疗疼痛 |
| WO2013055476A1 (en) | 2011-09-09 | 2013-04-18 | Anthrogenesis Corporation | Treatment of amyotrophic lateral sclerosis using placental stem cells |
| WO2013082417A1 (en) * | 2011-11-30 | 2013-06-06 | Anthrogenesis Corporation | Treatment using placental stem cells |
| CN104822384A (zh) * | 2012-03-30 | 2015-08-05 | 南加州大学 | 用于间充质干细胞诱导的免疫调节的组合物和治疗方法 |
| CA2869163A1 (en) * | 2012-03-30 | 2013-10-03 | University Of Central Florida Research Foundation, Inc. | Methods and compositions using fgf-8 to enhance cardiac regeneration and attenuate adverse cardiac remodeling |
| US9943551B2 (en) | 2012-08-15 | 2018-04-17 | Mimedx Group, Inc. | Tissue grafts composed of micronized placental tissue and methods of making and using the same |
| US9180145B2 (en) | 2012-10-12 | 2015-11-10 | Mimedx Group, Inc. | Compositions and methods for recruiting and localizing stem cells |
| EP3556215A1 (en) | 2012-12-14 | 2019-10-23 | Celularity, Inc. | Anoikis resistant placental stem cells and uses thereof |
| US10206977B1 (en) | 2013-01-18 | 2019-02-19 | Mimedx Group, Inc. | Isolated placental stem cell recruiting factors |
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2017
- 2017-11-16 US US15/815,668 patent/US20180071343A1/en not_active Abandoned
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2018
- 2018-04-26 AR ARP180101085A patent/AR111656A2/es unknown
- 2018-06-05 JP JP2018107325A patent/JP2018161133A/ja active Pending
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2020
- 2020-09-11 JP JP2020152481A patent/JP2021006041A/ja active Pending
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2022
- 2022-07-14 JP JP2022112809A patent/JP2022160449A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010021715A1 (en) * | 2008-08-20 | 2010-02-25 | Anthrogenesis Corporation | Treatment of stroke using isolated placental cells |
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