ATE271890T1 - Vorrichtung zur bluttrennung, insbesondere zur konzentrierung von hematopoietischen stammzellen - Google Patents

Vorrichtung zur bluttrennung, insbesondere zur konzentrierung von hematopoietischen stammzellen

Info

Publication number
ATE271890T1
ATE271890T1 AT99959629T AT99959629T ATE271890T1 AT E271890 T1 ATE271890 T1 AT E271890T1 AT 99959629 T AT99959629 T AT 99959629T AT 99959629 T AT99959629 T AT 99959629T AT E271890 T1 ATE271890 T1 AT E271890T1
Authority
AT
Austria
Prior art keywords
components
biological fluid
processing chamber
stem cells
separated
Prior art date
Application number
AT99959629T
Other languages
English (en)
Inventor
Claude Fell
Original Assignee
Biosafe Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosafe Sa filed Critical Biosafe Sa
Application granted granted Critical
Publication of ATE271890T1 publication Critical patent/ATE271890T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3698—Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT99959629T 1998-12-24 1999-12-24 Vorrichtung zur bluttrennung, insbesondere zur konzentrierung von hematopoietischen stammzellen ATE271890T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9802114 1998-12-24
PCT/IB1999/002053 WO2000038762A1 (en) 1998-12-24 1999-12-24 Blood separation system particularly for concentrating hematopoietic stem cells

Publications (1)

Publication Number Publication Date
ATE271890T1 true ATE271890T1 (de) 2004-08-15

Family

ID=11004802

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99959629T ATE271890T1 (de) 1998-12-24 1999-12-24 Vorrichtung zur bluttrennung, insbesondere zur konzentrierung von hematopoietischen stammzellen

Country Status (11)

Country Link
US (1) US6733433B1 (de)
EP (1) EP1144026B1 (de)
JP (1) JP4514338B2 (de)
CN (1) CN1182882C (de)
AT (1) ATE271890T1 (de)
AU (1) AU1675600A (de)
DE (1) DE69919029T2 (de)
ES (1) ES2224726T3 (de)
HK (1) HK1041454B (de)
PT (1) PT1144026E (de)
WO (1) WO2000038762A1 (de)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10134913C2 (de) 2001-07-18 2003-06-26 Hiberna Ag Vorrichtung und Verfahren zur Blutpräparation
US7201848B2 (en) * 2001-12-05 2007-04-10 Gambro Bct, Inc. Methods and apparatus for separation of particles
US8062837B2 (en) 2002-02-14 2011-11-22 Stemcyte, Inc. Plasma-depleted, not erythrocyte-depleted, cord blood compositions and method of making
US7241281B2 (en) 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US20040256331A1 (en) * 2002-10-04 2004-12-23 Arking E. James System and method for fractionation of a centrifuged sample
PL1641916T3 (pl) 2003-06-27 2016-08-31 Depuy Synthes Products Inc Regeneracja i naprawa tkanki nerwowej z wykorzystaniem komórek poporodowych
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
ITMI20031715A1 (it) 2003-09-05 2005-03-06 Dideco Spa Dispositivo di comando nella raccolta differenziata dei
US7060018B2 (en) 2003-09-11 2006-06-13 Cobe Cardiovascular, Inc. Centrifuge apparatus for processing blood
US7569026B2 (en) * 2003-10-02 2009-08-04 Terumo Kabushiki Kaisha Method of producing blood processing circuits and filter unit
US7261683B2 (en) * 2004-04-14 2007-08-28 Wagner Development, Inc. Conical piston solids discharge and pumping centrifugal separator
US7052451B2 (en) * 2004-04-14 2006-05-30 Wagner Development, Inc. Conical piston solids discharge centrifugal separator
DK1893253T3 (da) * 2005-03-23 2010-08-16 Biosafe Sa Integreret system til opsamling, forarbejdning og transplantation af celledelmængder, omfattende voksenstamceller til regenerativ medicin
US7364657B2 (en) * 2005-03-31 2008-04-29 Abbott Cardiovascular Systems Inc. Integrated system for on-site cell acquisition, processing, and delivery
US8048619B2 (en) 2005-06-02 2011-11-01 Stemcyte, Inc. Method of treating a hematopoietic associated disease or disorder with plasma-depleted, but not erythrocyte-depleted cord blood compositions
US20100210441A1 (en) * 2005-06-22 2010-08-19 Caridianbct, Inc. Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid
CN101227982B (zh) * 2005-06-22 2012-04-18 科安比司特公司 用于分离分立体积的复合液体的设备和方法
US7628749B2 (en) 2005-09-01 2009-12-08 Wagner Development Inc. Solids recovery using cross-flow microfilter and automatic piston discharge centrifuge
US7618361B2 (en) * 2005-09-01 2009-11-17 Wagner Development, Inc. Gas driven solids discharge and pumping piston for a centrifugal separator
US20070119508A1 (en) * 2005-11-29 2007-05-31 West Richard L Fluid Flow Diversion Valve and Blood Collection System Employing Same
US9175261B2 (en) 2005-12-16 2015-11-03 DePuy Synthes Products, Inc. Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation
CN103060263B (zh) 2005-12-29 2016-03-16 人类起源公司 胎盘干细胞群
US7998052B2 (en) * 2006-03-07 2011-08-16 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
GB0608451D0 (en) * 2006-04-28 2006-06-07 Ge Healthcare Bio Sciences Ab Centrifugal separation system
US8016736B2 (en) * 2006-10-20 2011-09-13 Caridianbct Biotechnologies, Llc Methods for washing a red blood cell component and for removing prions therefrom
US20080108955A1 (en) * 2006-11-02 2008-05-08 Blickhan Bryan J Flow Controllers
US20080108954A1 (en) * 2006-11-02 2008-05-08 Jean-Marie Mathias Flow Controllers
KR101569168B1 (ko) 2007-02-12 2015-11-13 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
JP5795476B2 (ja) 2007-09-28 2015-10-14 アンスロジェネシス コーポレーション ヒト胎盤灌流液およびヒト胎盤由来中間ナチュラルキラー細胞を使用した腫瘍抑制
DE102007059841B3 (de) * 2007-12-12 2009-04-23 Ab Skf Biokompatibles Verbindungsmodul für einen Fluidbehälter
US20090218535A1 (en) * 2008-02-27 2009-09-03 Andres Pasko Flow controllers for fluid circuits
US7976796B1 (en) * 2008-07-03 2011-07-12 Emcyte Corp. Centrifuge tube for separating and aspirating biological components
DK2330889T3 (en) 2008-08-20 2017-01-30 Anthrogenesis Corp Improved cell composition and process for making the same
DE102008047068B4 (de) 2008-09-12 2015-02-26 Walter Pobitschka Verfahren und Vorrichtung zur Trennung von Blut unter Einsatz einer Zentrifuge
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
CN102387867B (zh) 2008-12-29 2013-12-11 瓦格纳发展公司 具有一次性接触元件的固体排放离心式分离器
JP2010193879A (ja) * 2009-01-27 2010-09-09 Jms Co Ltd 臍帯血造血幹細胞の増殖制御方法およびその用途
US9272083B2 (en) 2009-05-29 2016-03-01 Endocellutions, Inc. Apparatus and methods for aspirating and separating components of different densities from a physiological fluid containing cells
WO2011005411A1 (en) * 2009-07-06 2011-01-13 Caridianbct, Inc. Apparatus and method for automatically loading washing solution in a multi-unit blood processor
DE102009040525B4 (de) * 2009-09-08 2015-02-05 Andreas Hettich Gmbh & Co. Kg Zentrifuge zum Trennen von Vollblut in Blutkomponenten, sowie fluidisch kommunizierende Behälter zum Einsetzen in die Zentrifuge, sowie Verfahren zur Gewinnung eines hochangereichten Thrombozytenkonzentrats aus Vollblut
CA2777718A1 (en) 2009-10-16 2011-04-21 University Of Medicine And Dentistry Of New Jersey Closed system separation of adherent bone marrow stem cells for regenerative medicine applications
KR101049201B1 (ko) * 2009-10-29 2011-07-14 토자이홀딩스 주식회사 말초혈액 내의 조혈 줄기세포 및 중간엽 줄기세포의 추출을 위한 바이오 디바이스
US9034280B2 (en) 2009-12-16 2015-05-19 General Electric Corporation High-throughput methods and systems for processing biological materials
KR200458000Y1 (ko) * 2010-01-07 2012-01-16 (주)아모레퍼시픽 잔량확인이 가능한 에어리스펌프를 갖는 화장품용기
ES2646750T3 (es) 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
NZ630009A (en) 2010-04-07 2016-05-27 Anthrogenesis Corp Angiogenesis using placental stem cells
EP2575925B1 (de) 2010-05-27 2014-10-15 Terumo BCT, Inc. Blutprozessor mit mehreren einheiten und temperaturmessung
EP2576073B1 (de) 2010-06-07 2018-06-13 Terumo BCT, Inc. Blutprozessor mit mehreren einheiten und volumenvorhersage
EP2593542B1 (de) 2010-07-13 2018-01-03 Anthrogenesis Corporation Verfahren zur erzeugung von natürlichen killerzellen
EP2603699A1 (de) * 2010-08-09 2013-06-19 KCI Licensing, Inc. System und verfahren zur messung des von einer piezoelektrischen pumpe angewandten drucks
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
EP2658557A1 (de) 2010-12-31 2013-11-06 Anthrogenesis Corporation Verbesserung der plazentastammzellenpotenz mit modulatorischen rna-molekülen
AU2012262273B2 (en) 2011-06-01 2017-09-14 Celularity Inc. Treatment of pain using placental stem cells
WO2013136943A1 (ja) * 2012-03-13 2013-09-19 テルモ株式会社 血液成分分離装置、及び遠心分離器
US20130252227A1 (en) * 2012-03-20 2013-09-26 Fenwal, Inc. Apparatus and Method for Providing Cryopreserved ECP-Treated Mononuclear Cells
US9022950B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
WO2014022275A1 (en) 2012-08-01 2014-02-06 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9149576B2 (en) 2012-10-11 2015-10-06 Magnolia Medical Technologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
CA2931983C (en) 2012-11-30 2021-12-07 Magnolia Medical Technologies, Inc. Syringe based fluid diversion mechanism for bodily-fluid sampling
EP3626172B1 (de) 2012-12-04 2023-03-22 Magnolia Medical Technologies, Inc. Vorrichtung zur sterilen körperflüssigkeitsentnahme
US10772548B2 (en) 2012-12-04 2020-09-15 Magnolia Medical Technologies, Inc. Sterile bodily-fluid collection device and methods
US10603665B2 (en) 2013-01-29 2020-03-31 Endocellutions, Inc. Cell concentration devices and methods that include an insert defining a lumen and a cannula assembly
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
JP2016509863A (ja) * 2013-03-15 2016-04-04 ラーソン、マルクス カーレ、トールレイフＬＡＲＳＳＯＮ， Ｍａｒｃｕｓ Ｋａｒｅ， Ｔｏｒｌｅｉｆ 細胞、臍帯血収集のための方法及び装置、並びに細胞の単離のための方法及び装置
US9427503B2 (en) * 2013-03-15 2016-08-30 Corvivo Inc. Cardiotomy suction tube system with multiple tips
ES2424272B1 (es) * 2013-07-23 2014-01-29 Riera Nadeu, S.A. Supercentrífuga con dispositivo no intrusivo de extracción de sólido y procedimiento de extracción del mismo
CN103342748B (zh) * 2013-07-26 2015-04-08 中国人民解放军第三军医大学第一附属医院 天然软骨基质主要成分-ⅱ型胶原蛋白提取专用装置
EP3660140A1 (de) 2014-01-31 2020-06-03 DSM IP Assets B.V. Zentrifuge zur behandlung von fettgewebe und verfahren zur verwendung
WO2015160320A1 (en) * 2014-04-15 2015-10-22 Promedart Biyoteknoloji Ve Ozel Saglik Hizmetleri Sanayi Ticaret Limited Sirketi A separation system
WO2015186057A1 (en) 2014-06-04 2015-12-10 Biosafe S.A. System for multi-processing and separation of biological fluids
TW202315948A (zh) 2014-11-05 2023-04-16 美商奇諾治療有限公司 用於轉導作用及細胞處理之方法
WO2016081737A1 (en) * 2014-11-19 2016-05-26 The Regents Of The University Of Colorado, A Body Corporate Apparatus, method, and system for filter based cell capture and labeling with configurable laydown area
JP6700282B2 (ja) * 2014-12-19 2020-05-27 ビオセフ エス・アー 生物学的液体の連続処理
CN104474598B (zh) * 2015-01-05 2016-06-08 浙江保尔曼生物科技有限公司 血浆分离装置
CN107635668B (zh) 2015-05-07 2019-12-03 生物安全股份有限公司 用于将生物流体连续处理并分离成组分的装置、系统和方法
EP3307359B1 (de) 2015-06-12 2020-07-01 Gregory J. Bullington Vorrichtung zum spritzenbasierten fluidtransfer zur probenahme von körperflüssigkeiten
US10010282B2 (en) 2015-07-24 2018-07-03 Kurin, Inc. Blood sample optimization system and blood contaminant sequestration device and method
WO2017041087A1 (en) 2015-09-03 2017-03-09 Bullington Gregory J Apparatus and methods for maintaining sterility of a specimen container
KR102553195B1 (ko) 2016-07-29 2023-07-07 주노 쎄러퓨티크스 인코퍼레이티드 항-cd19 항체에 대한 항-이디오타입 항체
CN106110750B (zh) * 2016-08-15 2018-10-16 鲁绍荣 一种高效血液回收机
MA46194A (fr) 2016-09-12 2019-07-17 Juno Therapeutics Inc Ensembles de poches de bioréacteur de perfusion
EP3295972B1 (de) 2016-09-14 2020-11-25 Fenwal, Inc. Zellverarbeitungssytem und -verfahren mit fülloptionen
WO2018073615A1 (en) 2016-10-21 2018-04-26 Longboat Explorers Ab Methods and compositions for generating hematopoietic cells
EP3858395A1 (de) 2016-12-01 2021-08-04 Fenwal, Inc. Füll- und endbearbeitungssysteme und -verfahren
WO2018106732A1 (en) 2016-12-05 2018-06-14 Juno Therapeutics, Inc. Production of engineered cells for adoptive cell therapy
JP6309606B1 (ja) * 2016-12-21 2018-04-11 三井電気精機株式会社 遠心分離システム
US10827964B2 (en) 2017-02-10 2020-11-10 Kurin, Inc. Blood contaminant sequestration device with one-way air valve and air-permeable blood barrier with closure mechanism
CA3053539A1 (en) 2017-02-27 2018-08-30 Juno Therapeutics, Inc. Compositions, articles of manufacture and methods related to dosing in cell therapy
KR102657962B1 (ko) * 2017-05-12 2024-04-16 싸이노지 프로덕츠 피티와이 엘티디 소형 역류 원심 분리기 시스템
US10449555B2 (en) * 2017-05-16 2019-10-22 Robert Bret Carr Centrifugal separator with annular piston for solids extrusion
WO2018227161A1 (en) * 2017-06-08 2018-12-13 Patrick Pennie Dual piston centrifuge tube
CN111246861A (zh) 2017-07-29 2020-06-05 朱诺治疗学股份有限公司 扩增表达重组受体的细胞的试剂
GB201713252D0 (en) * 2017-08-18 2017-10-04 Biosafe Sa Piston movement
GB201713981D0 (en) 2017-08-31 2017-10-18 Biosafe Sa Centrifugal separation chamber
EP3679370A1 (de) 2017-09-07 2020-07-15 Juno Therapeutics, Inc. Verfahren zur identifizierung von zellulären attributen im zusammenhang mit den ergebnissen einer zelltherapie
CN116250868A (zh) 2017-09-12 2023-06-13 木兰医药技术股份有限公司 流体控制装置及其使用方法
AU2018360801A1 (en) 2017-11-01 2020-05-14 Celgene Corporation Process for producing a T cell composition
CA3084514A1 (en) 2017-11-01 2019-05-09 Juno Therapeutics, Inc. Process for generating therapeutic compositions of engineered cells
KR20200095487A (ko) 2017-11-10 2020-08-10 주노 쎄러퓨티크스 인코퍼레이티드 폐쇄-시스템 극저온 용기
CN115553822A (zh) 2017-12-07 2023-01-03 木兰医药技术股份有限公司 流体控制装置及其使用方法
GB201720405D0 (en) 2017-12-07 2018-01-24 Biosafe Sa A bioprocessing system
EP3720874A1 (de) 2017-12-08 2020-10-14 Juno Therapeutics, Inc. Verfahren zur herstellung einer zusammensetzung von gentechnisch veränderten t-zellen
EP3720949A1 (de) 2017-12-08 2020-10-14 Juno Therapeutics, Inc. Serumfreie medienformulierung zur anzucht von zellen und verwendungsverfahren dafür
WO2019113559A2 (en) 2017-12-08 2019-06-13 Juno Therapeutics, Inc. Phenotypic markers for cell therapy and related methods
JP6425793B2 (ja) * 2017-12-12 2018-11-21 三井電気精機株式会社 遠心分離装置
US11191880B2 (en) * 2018-05-16 2021-12-07 Fenwal, Inc. Fill and finish systems and methods for small volume processing
US11911553B2 (en) * 2018-07-06 2024-02-27 Fenwal, Inc. Systems and methods for concentrating cells with a syringe and a centrifuge
AU2019316647A1 (en) 2018-08-09 2021-02-25 Juno Therapeutics, Inc. Methods for assessing integrated nucleic acids
SG11202101204TA (en) 2018-08-09 2021-03-30 Juno Therapeutics Inc Processes for generating engineered cells and compositions thereof
JP7504891B2 (ja) 2018-09-11 2024-06-24 ジュノー セラピューティクス インコーポレイテッド 操作された細胞組成物のマススペクトロメトリー分析のための方法
CN109321458B (zh) * 2018-10-17 2023-03-24 深圳市深研生物科技有限公司 一种制备细胞的方法
CN109225673B (zh) * 2018-10-24 2024-05-31 上海瑛泰医疗器械股份有限公司 一种血液离心分离机
WO2020089343A1 (en) 2018-10-31 2020-05-07 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
BR112021008289A2 (pt) 2018-11-01 2021-10-26 Juno Therapeutics, Inc. Métodos para tratamento utilizando receptores de antígeno quimérico específico para antígeno de maturação de célula b
US20210393691A1 (en) 2018-11-06 2021-12-23 Juno Therapeutics, Inc. Process for producing genetically engineered t cells
WO2020102770A1 (en) 2018-11-16 2020-05-22 Juno Therapeutics, Inc. Methods of dosing engineered t cells for the treatment of b cell malignancies
PL3886894T3 (pl) 2018-11-30 2024-07-01 Juno Therapeutics, Inc. Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej
WO2020113194A2 (en) 2018-11-30 2020-06-04 Juno Therapeutics, Inc. Methods for treatment using adoptive cell therapy
US20210220817A1 (en) * 2018-12-08 2021-07-22 Min Wei Apparatus For Manufacturing Cell Therapy Product
JP2022523153A (ja) 2019-02-08 2022-04-21 マグノリア メディカル テクノロジーズ，インコーポレイテッド 体液採取及び分配のための装置及び方法
US11857321B2 (en) 2019-03-11 2024-01-02 Magnolia Medical Technologies, Inc. Fluid control devices and methods of using the same
CN114269371A (zh) 2019-06-12 2022-04-01 朱诺治疗学股份有限公司 细胞介导的细胞毒性疗法与促存活bcl2家族蛋白的抑制剂的组合疗法
CN110456033A (zh) * 2019-07-03 2019-11-15 深圳市深研生物科技有限公司 用于调整含有细胞的液体样品的密度和或体积的系统
US11478755B2 (en) 2019-08-15 2022-10-25 Fenwal, Inc. Small volume processing systems and methods
CN114555112A (zh) 2019-08-22 2022-05-27 朱诺治疗学股份有限公司 T细胞疗法和zeste增强子同源物2(ezh2)抑制剂的组合疗法及相关方法
JP2022546396A (ja) 2019-08-30 2022-11-04 ジュノー セラピューティクス インコーポレイテッド 細胞を分類するための機械学習方法
EP4234019A3 (de) 2019-10-18 2023-09-13 Amniotics AB Verfahren und vorrichtungen zur gewinnung von mesenchymalen stammzellen aus fruchtwasser und davon abgeleitete zellen
US20210123937A1 (en) 2019-10-24 2021-04-29 Fenwal, Inc. Small volume processing systems and methods with capacitive sensing
KR20220101641A (ko) 2019-10-30 2022-07-19 주노 테라퓨틱스 게엠베하 세포 선택 및/또는 자극 장치 및 사용 방법
US20220412954A1 (en) 2019-11-05 2022-12-29 Juno Therapeutics, Inc. Methods of determining attributes of therapeutic t cell compositions
KR20220132527A (ko) 2019-12-06 2022-09-30 주노 쎄러퓨티크스 인코퍼레이티드 Ｂ 세포 악성 종양을 치료하기 위한 세포 요법과 연관된 독성 및 반응과 관련된 방법
WO2021113780A1 (en) 2019-12-06 2021-06-10 Juno Therapeutics, Inc. Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
CA3163897A1 (en) 2019-12-06 2021-06-10 Juno Therapeutics, Inc. Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
WO2021151008A1 (en) 2020-01-24 2021-07-29 Juno Therapuetics, Inc. Methods for dosing and treatment of follicular lymphoma and marginal zone lymphoma in adoptive cell therapy
CN115427550A (zh) 2020-01-28 2022-12-02 朱诺治疗学股份有限公司 T细胞转导方法
CA3170153A1 (en) 2020-02-12 2021-08-19 Juno Therapeutics, Inc. Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof
JP2023519098A (ja) 2020-02-12 2023-05-10 ジュノー セラピューティクス インコーポレイテッド Ｃｄ１９指向性キメラ抗原受容体ｔ細胞組成物ならびにその方法および使用
EP4132542A2 (de) 2020-04-10 2023-02-15 Juno Therapeutics, Inc. Verfahren und verwendungen in zusammenhang mit einer mit einem chimären antigenrezeptor gegen b-zellreifungsantigen manipulierten zelltherapie
CN115835873A (zh) 2020-05-13 2023-03-21 朱诺治疗学股份有限公司 用于产生表达重组受体的供体分批细胞的方法
JP2023528215A (ja) 2020-05-13 2023-07-04 ジュノー セラピューティクス インコーポレイテッド 臨床応答に関連する特徴量の特定方法およびその使用
EP4192868A1 (de) 2020-08-05 2023-06-14 Juno Therapeutics, Inc. Antiidiotypische antikörper gegen ror1-gerichtete bindungsdomänen und zugehörige zusammensetzungen und verfahren
WO2022133030A1 (en) 2020-12-16 2022-06-23 Juno Therapeutics, Inc. Combination therapy of a cell therapy and a bcl2 inhibitor
EP4314280A1 (de) 2021-03-22 2024-02-07 Juno Therapeutics, Inc. Verfahren zur beurteilung der wirksamkeit von virusvektorpartikeln
JP2024511418A (ja) 2021-03-22 2024-03-13 ジュノー セラピューティクス インコーポレイテッド 治療用細胞組成物の効力を決定する方法
AU2022246593A1 (en) 2021-03-29 2023-10-12 Juno Therapeutics, Inc. Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
CN113318287A (zh) * 2021-05-31 2021-08-31 衷博瑞佳生物技术(上海)有限公司 一种带内核的活塞式生物液体分离杯及其分离方法
GB2605850B (en) 2021-07-06 2023-04-26 Cellularorigins Ltd Bioprocessing system
CN113943651B (zh) * 2021-11-17 2023-08-18 北京集美生物科技有限公司 一种干细胞提取离心抽取工艺
WO2023230548A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Method for predicting response to a t cell therapy
WO2023230581A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Methods of manufacturing t cell therapies
WO2023250400A1 (en) 2022-06-22 2023-12-28 Juno Therapeutics, Inc. Treatment methods for second line therapy of cd19-targeted car t cells
WO2024032582A1 (en) * 2022-08-09 2024-02-15 Sino-Biocan (Shanghai) Biotech Ltd. Managing peripheral blood cells
WO2024124132A1 (en) 2022-12-09 2024-06-13 Juno Therapeutics, Inc. Machine learning methods for predicting cell phenotype using holographic imaging

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737096A (en) 1971-12-23 1973-06-05 Ibm Blood processing control apparatus
JPS59500340A (ja) * 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4946434A (en) 1986-07-22 1990-08-07 Haemonetics Corporation Disposable manifold and valve
US5641622A (en) 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
JP2528058B2 (ja) * 1992-05-28 1996-08-28 川澄化学工業株式会社 血液成分分離装置
JP3184052B2 (ja) * 1994-08-17 2001-07-09 川澄化学工業株式会社 血液成分分離装置
WO1997015399A1 (en) * 1996-04-24 1997-05-01 Claude Fell Cell separation system for biological fluids like blood
US6098646A (en) * 1997-02-19 2000-08-08 Ecolab Inc. Dispensing system with multi-port valve for distributing use dilution to a plurality of utilization points and position sensor for use thereon

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CN1182882C (zh) 2005-01-05
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AU1675600A (en) 2000-07-31
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US6733433B1 (en) 2004-05-11
EP1144026B1 (de) 2004-07-28
EP1144026A1 (de) 2001-10-17
JP4514338B2 (ja) 2010-07-28
DE69919029D1 (de) 2004-09-02
HK1041454A1 (en) 2002-07-12
ES2224726T3 (es) 2005-03-01
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