KR101943490B1 - 피리다지논 화합물 및 낭성 섬유증을 치료하는 방법 - Google Patents
피리다지논 화합물 및 낭성 섬유증을 치료하는 방법 Download PDFInfo
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- KR101943490B1 KR101943490B1 KR1020157027647A KR20157027647A KR101943490B1 KR 101943490 B1 KR101943490 B1 KR 101943490B1 KR 1020157027647 A KR1020157027647 A KR 1020157027647A KR 20157027647 A KR20157027647 A KR 20157027647A KR 101943490 B1 KR101943490 B1 KR 101943490B1
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- 0 Cc1ccccc1* Chemical compound Cc1ccccc1* 0.000 description 11
- VFHYCHYTIVAZPE-UHFFFAOYSA-N CCN(C(CN1N=Cc([n](Cc2ccccn2)c2ccccc22)c2C1=O)=O)c(cc1)cc(O2)c1OC2(F)F Chemical compound CCN(C(CN1N=Cc([n](Cc2ccccn2)c2ccccc22)c2C1=O)=O)c(cc1)cc(O2)c1OC2(F)F VFHYCHYTIVAZPE-UHFFFAOYSA-N 0.000 description 1
- BWCMHDPNNHNODV-UHFFFAOYSA-N CCOC(C(c1c(C(OCC)=O)[n](C)c2c1[s]c(C)c2)=O)=O Chemical compound CCOC(C(c1c(C(OCC)=O)[n](C)c2c1[s]c(C)c2)=O)=O BWCMHDPNNHNODV-UHFFFAOYSA-N 0.000 description 1
- XSRPXHCZHJMVFL-UHFFFAOYSA-N CCOC(C(c1c2[n](C)c3ccccc13)=NN(c1ccc(C)cc1)C2=O)=O Chemical compound CCOC(C(c1c2[n](C)c3ccccc13)=NN(c1ccc(C)cc1)C2=O)=O XSRPXHCZHJMVFL-UHFFFAOYSA-N 0.000 description 1
- ACWHBROOZGSOCL-UHFFFAOYSA-N CCc(cc1)ccc1N(CC)C(CN1N=C(Cc2cccnc2)c2cc(C)ccc2C1=O)=O Chemical compound CCc(cc1)ccc1N(CC)C(CN1N=C(Cc2cccnc2)c2cc(C)ccc2C1=O)=O ACWHBROOZGSOCL-UHFFFAOYSA-N 0.000 description 1
- FRXORJVDQUVAMA-UHFFFAOYSA-N CCc(cc1)ccc1N(CC)C(CN1N=C(Cc2cccnc2)c2ccc(C)cc2C1=O)=O Chemical compound CCc(cc1)ccc1N(CC)C(CN1N=C(Cc2cccnc2)c2ccc(C)cc2C1=O)=O FRXORJVDQUVAMA-UHFFFAOYSA-N 0.000 description 1
- YWKBHVXGALEDRE-UHFFFAOYSA-N CCc(cc1)ccc1N(CC)C(CN1N=C(c2ccccc2)c2ccccc2C1=O)=O Chemical compound CCc(cc1)ccc1N(CC)C(CN1N=C(c2ccccc2)c2ccccc2C1=O)=O YWKBHVXGALEDRE-UHFFFAOYSA-N 0.000 description 1
- NFOLYLKNIZNZCJ-UHFFFAOYSA-N CN(C(CN(C(c1c2)=O)N=C(c3cc(C#N)ccc3)c1ccc2OC)=O)c(cc1)cc(O2)c1OC2(F)F Chemical compound CN(C(CN(C(c1c2)=O)N=C(c3cc(C#N)ccc3)c1ccc2OC)=O)c(cc1)cc(O2)c1OC2(F)F NFOLYLKNIZNZCJ-UHFFFAOYSA-N 0.000 description 1
- YONBGKKMAICRSA-UHFFFAOYSA-N COc(cc12)ccc1C(c1cc(Cl)ccc1)=NN(CC(C1(CC1)c(cc1O3)ccc1OC3(F)F)=O)C2=O Chemical compound COc(cc12)ccc1C(c1cc(Cl)ccc1)=NN(CC(C1(CC1)c(cc1O3)ccc1OC3(F)F)=O)C2=O YONBGKKMAICRSA-UHFFFAOYSA-N 0.000 description 1
- KMOWLHZEFCOFSK-UHFFFAOYSA-N Cc1nc(ccc(N(C)C(CN(C(c2c3)=O)N=C(c4cccc(F)c4)c2ccc3O)=O)c2)c2[o]1 Chemical compound Cc1nc(ccc(N(C)C(CN(C(c2c3)=O)N=C(c4cccc(F)c4)c2ccc3O)=O)c2)c2[o]1 KMOWLHZEFCOFSK-UHFFFAOYSA-N 0.000 description 1
- RWQXWOCSCNDWCZ-UHFFFAOYSA-N O=C(CBr)C1(CC1)c(cc1)cc(O2)c1OC2(F)F Chemical compound O=C(CBr)C1(CC1)c(cc1)cc(O2)c1OC2(F)F RWQXWOCSCNDWCZ-UHFFFAOYSA-N 0.000 description 1
- FXXJJBDOKNNGQF-UHFFFAOYSA-N OC(c(cc1)cc(C(NN2)=O)c1C2=O)=O Chemical compound OC(c(cc1)cc(C(NN2)=O)c1C2=O)=O FXXJJBDOKNNGQF-UHFFFAOYSA-N 0.000 description 1
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| PCT/US2014/026623 WO2014160440A1 (en) | 2013-03-13 | 2014-03-13 | Pyridazinone compounds and methods for the treatment of cystic fibrosis |
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- 2014-03-13 CN CN201480021457.9A patent/CN105307655B/zh not_active Expired - Fee Related
- 2014-03-13 WO PCT/US2014/026623 patent/WO2014160440A1/en not_active Ceased
- 2014-03-13 HK HK16108633.8A patent/HK1220610A1/zh unknown
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- 2014-03-13 BR BR112015023328A patent/BR112015023328A2/pt not_active Application Discontinuation
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