KR101854926B1 - 성 호르몬 결합 글로불린 (shbg)에 대한 자연 안티센스 전사체의 저해에 의한 성 호르몬 결합 글로불린 (shbg) 관련된 질환의 치료 - Google Patents
성 호르몬 결합 글로불린 (shbg)에 대한 자연 안티센스 전사체의 저해에 의한 성 호르몬 결합 글로불린 (shbg) 관련된 질환의 치료 Download PDFInfo
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- KR101854926B1 KR101854926B1 KR1020127017861A KR20127017861A KR101854926B1 KR 101854926 B1 KR101854926 B1 KR 101854926B1 KR 1020127017861 A KR1020127017861 A KR 1020127017861A KR 20127017861 A KR20127017861 A KR 20127017861A KR 101854926 B1 KR101854926 B1 KR 101854926B1
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
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- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29373910P | 2010-01-11 | 2010-01-11 | |
| US61/293,739 | 2010-01-11 | ||
| PCT/US2011/020768 WO2011085347A2 (en) | 2010-01-11 | 2011-01-11 | Treatment of sex hormone binding globulin (shbg) related diseases by inhibition of natural antisense transcript to shbg |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120112530A KR20120112530A (ko) | 2012-10-11 |
| KR101854926B1 true KR101854926B1 (ko) | 2018-05-04 |
Family
ID=44306189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127017861A Expired - Fee Related KR101854926B1 (ko) | 2010-01-11 | 2011-01-11 | 성 호르몬 결합 글로불린 (shbg)에 대한 자연 안티센스 전사체의 저해에 의한 성 호르몬 결합 글로불린 (shbg) 관련된 질환의 치료 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9200277B2 (enExample) |
| EP (1) | EP2524039B1 (enExample) |
| JP (1) | JP6027893B2 (enExample) |
| KR (1) | KR101854926B1 (enExample) |
| CN (1) | CN102803493B (enExample) |
| CA (1) | CA2786535C (enExample) |
| DK (1) | DK2524039T3 (enExample) |
| ES (1) | ES2664866T3 (enExample) |
| NO (1) | NO2524039T3 (enExample) |
| RU (1) | RU2611191C2 (enExample) |
| WO (1) | WO2011085347A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101854926B1 (ko) | 2010-01-11 | 2018-05-04 | 큐알엔에이, 인크. | 성 호르몬 결합 글로불린 (shbg)에 대한 자연 안티센스 전사체의 저해에 의한 성 호르몬 결합 글로불린 (shbg) 관련된 질환의 치료 |
| JP5976548B2 (ja) * | 2010-02-22 | 2016-08-23 | カッパーアールエヌエー,インコーポレイテッド | Pycr1に対する天然アンチセンス転写物の阻害によるピロリン−5−カルボン酸レダクターゼ1(pycr1)関連疾患の治療 |
| US9920317B2 (en) | 2010-11-12 | 2018-03-20 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
| CA2817256A1 (en) | 2010-11-12 | 2012-05-18 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| CN115927242A (zh) | 2012-05-11 | 2023-04-07 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| CN104507489B (zh) | 2012-05-11 | 2016-07-13 | 杰姆维克斯&凯尔有限公司 | 用于预防和治疗类风湿性关节炎的组合物 |
| AU2013262699A1 (en) | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating ATP2A2 expression |
| JP2015518710A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | ヘモグロビン遺伝子ファミリー発現を調節するための組成物及び方法 |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| US20150133362A1 (en) | 2012-05-16 | 2015-05-14 | Rana Therapeutics, Inc. | Compositions and methods for modulating gene expression |
| EA201492122A1 (ru) | 2012-05-16 | 2015-10-30 | Рана Терапьютикс, Инк. | Композиции и способы для модулирования экспрессии utrn |
| US20150152410A1 (en) | 2012-05-16 | 2015-06-04 | Rana Therapeutics, Inc. | Compositions and methods for modulating mecp2 expression |
| EA201492123A1 (ru) | 2012-05-16 | 2015-10-30 | Рана Терапьютикс, Инк. | Композиции и способы для модулирования экспрессии семейства генов smn |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| CN105535931A (zh) | 2013-06-07 | 2016-05-04 | 凯尔杰姆维克斯有限公司 | 在癌症免疫疗法中有用的生物标记 |
| EP3011967B1 (en) | 2013-06-21 | 2020-06-17 | Gemvax & Kael Co., Ltd. | Hormone secretion regulator, composition containing same, and method for controlling hormone secretion using same |
| JP6553605B2 (ja) | 2013-11-22 | 2019-07-31 | ジェムバックス アンド カエル カンパニー,リミティド | 血管新生抑制活性を有するペプチド、及びそれを含む組成物 |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
| CN106456697B (zh) | 2014-04-11 | 2019-12-17 | 珍白斯凯尔有限公司 | 具有纤维化抑制活性的肽和含有其的组合物 |
| KR102232320B1 (ko) | 2014-04-30 | 2021-03-26 | 주식회사 젬백스앤카엘 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| CA2966044A1 (en) | 2014-10-30 | 2016-05-06 | The General Hospital Corporation | Methods for modulating atrx-dependent gene repression |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| CN107405380B (zh) | 2015-02-27 | 2021-04-20 | 珍白斯凯尔有限公司 | 用于预防听觉损伤的肽及其包含该肽的组合物 |
| EP3271460A4 (en) | 2015-03-17 | 2019-03-13 | The General Hospital Corporation | RNA INTERACTOM OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1) |
| EP3318265B1 (en) | 2015-07-02 | 2021-08-18 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| CN105223364B (zh) * | 2015-10-10 | 2018-02-23 | 广西医科大学 | 血清shbg蛋白作为肺结核病血清标志物及其应用 |
| ES2949697T3 (es) | 2016-04-07 | 2023-10-02 | Gemvax & Kael Co Ltd | Péptido que tiene efectos de aumento de la actividad telomerasa y de extensión de los telómeros, y composición que contienen el mismo |
| WO2018118197A1 (en) * | 2016-12-21 | 2018-06-28 | Richard Postrel | Healthier aging in domesticated animals |
| WO2021262919A2 (en) | 2020-06-26 | 2021-12-30 | The Research Foundation For The State University Of New York | 5-halouracil-modified micrornas and their use in the treatment of cancer |
| EP4649175A2 (en) * | 2023-01-11 | 2025-11-19 | Arima Genomics, Inc. | Nucleic acid probes |
| CN117959437A (zh) * | 2024-01-24 | 2024-05-03 | 江南大学 | Shbg基因作为靶点在抑制类风湿关节炎中巨噬细胞极化的应用 |
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| US5550111A (en) | 1984-07-11 | 1996-08-27 | Temple University-Of The Commonwealth System Of Higher Education | Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof |
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| Cancer Gene Therapy, Vol.7, No.12, 2000 p.S5 |
| Proceedings of the American Association for Cancer Research,2000, 41, 741 |
Also Published As
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|---|---|
| CA2786535C (en) | 2019-03-26 |
| US20120277290A1 (en) | 2012-11-01 |
| CN102803493A (zh) | 2012-11-28 |
| WO2011085347A2 (en) | 2011-07-14 |
| EP2524039A2 (en) | 2012-11-21 |
| US9200277B2 (en) | 2015-12-01 |
| RU2012127703A (ru) | 2014-02-20 |
| CA2786535A1 (en) | 2011-07-14 |
| JP2013516197A (ja) | 2013-05-13 |
| JP6027893B2 (ja) | 2016-11-16 |
| US20160046942A1 (en) | 2016-02-18 |
| DK2524039T3 (en) | 2018-03-12 |
| RU2611191C2 (ru) | 2017-02-21 |
| WO2011085347A3 (en) | 2011-12-29 |
| NO2524039T3 (enExample) | 2018-04-28 |
| KR20120112530A (ko) | 2012-10-11 |
| US10696966B2 (en) | 2020-06-30 |
| EP2524039A4 (en) | 2013-11-06 |
| ES2664866T3 (es) | 2018-04-23 |
| CN102803493B (zh) | 2018-07-31 |
| EP2524039B1 (en) | 2017-11-29 |
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